Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(75 productos)
- CETP(20 productos)
- Anhídrido carbónico(188 productos)
- Caseína quinasa(137 productos)
- DHFR(34 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(296 productos)
- FAAH(65 productos)
- FXR(59 productos)
- Factor Xa(85 productos)
- Ácido graso sintasa(37 productos)
- Ferroptosis(221 productos)
- GR(3 productos)
- GSNOR(4 productos)
- Glucoquinasa(56 productos)
- HIF / HIF Prolilhidroxilasa(146 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(35 productos)
- IDO(84 productos)
- LDL(8 productos)
- Lipasa(105 productos)
- Lípido(62 productos)
- Lipoxigenasa(133 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(40 productos)
- P450(6 productos)
- PAI-1(26 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(169 productos)
- Fosfolipasa(82 productos)
- ROR(45 productos)
- Receptor de retinoides(28 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(29 productos)
- Transportador(46 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 9132 productos de "Metabolismo"
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FABP-IN-2
CAS:FABP-IN-2, a novel ligand for FABP3, demonstrates inhibition of both FABP3 and FABP4 with IC50 values of 1.16 μM and 4.27 μM, respectively.Fórmula:C25H21ClN2O3Forma y color:SolidPeso molecular:432.9hCAXII-IN-1
CAS:hCAXII-IN-1 selectively inhibits HCA IX/XII, promising for new cancer drug development.Fórmula:C20H17NO5Forma y color:SolidPeso molecular:351.35ENPP1 inhibitor 43
CAS:ENPP1 inhibitor 43 is a novel small molecule for cancer immunotherapy.Fórmula:C16H18N6O3SForma y color:SolidPeso molecular:374.42PDE4-IN-11
CAS:<p>PDE4-IN-11: Potent PDE4 inhibitor with strong bronchodilatory and anti-inflammatory effects for airway disease research.</p>Fórmula:C21H19FN2O2Forma y color:SolidPeso molecular:350.39Xanthine oxidase-IN-4
CAS:Xanthine oxidase-IN-4: an oral XO inhibitor with 0.039 μM IC50, useful for hyperuricemia/gout research.Fórmula:C15H13N5O2Forma y color:SolidPeso molecular:295.3PRRSV/CD163-IN-1
CAS:PRRSV/CD163-IN-1 blocks PRRSV GP2a/GP4 and CD163-SRCR5, aiding PRRS research.Fórmula:C25H24FN5O5S2Forma y color:SolidPeso molecular:557.62ICI 153110
CAS:ICI 153110: Oral phosphodiesterase inhibitor for treating congestive heart failure, has inotropic, vasodilator effects.Fórmula:C11H11N3OPureza:98%Forma y color:SolidPeso molecular:201.22Xanthine oxidase-IN-5
CAS:Xanthine oxidase-IN-5: oral XO inhibitor, IC50 = 0.70 μM, LE = 0.33, LLE = 3.41, reduces uric acid in rats.Fórmula:C18H16FN3O3Forma y color:SolidPeso molecular:341.34Lp-PLA2-IN-3
CAS:<p>Lp-PLA2-IN-3: Potent oral inhibitor of human Lp-PLA2 with a 14 nM IC50.</p>Fórmula:C20H13ClF3N3O3SPureza:99.65%Forma y color:SolidPeso molecular:467.85Hydroxychlorodenafil
CAS:Hydroxychlorodenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil.Fórmula:C19H23ClN4O3Forma y color:SolidPeso molecular:390.86HS79
CAS:HS-79, a Fasnall enantiomer, selectively inhibits FASN with an IC50 of 1.57 μM, blocking tritiated acetate lipid incorporation.Fórmula:C19H22N4SPureza:98%Forma y color:SolidPeso molecular:338.47Boc-Glu(OBzl)-OSu
CAS:Boc-Glu(OBzl)-OSu can be used for the synthesis of solid phase peptides containing benzyl glutamate residues.Fórmula:C21H26N2O8Forma y color:SolidPeso molecular:434.44PDE5-IN-4
CAS:PDE5-IN-4, a phosphodiesterase 5 (PDE5) inhibitor, is utilized in research concerning acute myocardial infarction and reperfusion-related damage,Fórmula:C21H27N5O5SForma y color:SolidPeso molecular:461.53Oxagrelate
CAS:Oxagrelate inhibits cAMP phosphodiesterase and reduces platelet aggregation by collagen and ADP.Fórmula:C14H16N2O4Forma y color:SolidPeso molecular:276.29Andolast
CAS:Andolast (CR-2039) is an anti-allergic for asthma and COPD, inhibiting IgE synthesis and improving airflow.Fórmula:C15H11N9OForma y color:SolidPeso molecular:333.31sEH inhibitor-14
CAS:sEH inhibitor-14, a benzoxazolone-5-urea analogue, acts as an efficient soluble Epoxide Hydrolase (sEH) inhibitor, demonstrating significant activity with anFórmula:C16H12F3N3O4Forma y color:SoildPeso molecular:367.28Deltazinone
CAS:Deltazinone selectively inhibits PDEδ with low cytotoxicity, mimicking PDEδ knockdown in human pancreatic cancer cells.Fórmula:C27H31N5O2Pureza:98%Forma y color:SolidPeso molecular:457.57SGK1 inhibitor
CAS:SGK1 inhibitor targets SGK1/2 over SGK3, blocks GSK3β phosphorylation, lowers HCC1954 cell viability with BYL719, and reduces tumor growth in mice.Fórmula:C17H12Cl2N6O2SForma y color:SolidPeso molecular:435.29CAY10485
CAS:CAY10485 blocks human ACAT-1 & ACAT-2 (IC50: 95 & 81 μM) and hinders oxidation of LDL by 91% at 2 μM, possibly impacting atherosclerosis development.Fórmula:C27H27NO7Forma y color:SolidPeso molecular:477.51Dapaconazole
CAS:Dapaconazole is used as a drug candidate for antifungals.Fórmula:C19H15Cl2F3N2OForma y color:SolidPeso molecular:415.24Enpp-1-IN-5
CAS:<p>Enpp-1-IN-5 is a potent enpp-1 inhibitor with potential in cancer and infectious disease research.</p>Fórmula:C17H26N6O4SForma y color:SolidPeso molecular:410.49Acetaldophosphamide
CAS:Acetaldophosphamide is a novel stable aldophosphamide analog.Fórmula:C11H21Cl2N2O6PForma y color:SolidPeso molecular:379.17mIDH1-IN-1
CAS:mIDH1-IN-1 is a selective mIDH1 inhibitor (IC50: 961.5 nM), blocks 2-HG production, and hinders IDH1 mutant cell growth (IC50: 41.8 nM).Fórmula:C25H27N3O5Forma y color:SolidPeso molecular:449.5UK-414,495
CAS:UK-414,495 is a potent, selective inhibitor of the neutral endopeptidase, the enzyme normally serves to break down the neuropeptide VIP.Fórmula:C16H25N3O3SForma y color:SolidPeso molecular:339.45Xanthine oxidoreductase-IN-2
CAS:<p>Xanthine oxidoreductase-IN-2 inhibits XOR with 7.2 nM IC50 and shows hypouricemic effects in mice.</p>Fórmula:C21H19N3O2Forma y color:SolidPeso molecular:345.39Glucokinase activator 3
CAS:Glucokinase activator 3: potent GK activator, AC50=38 nM, potential for type 2 diabetes research.Fórmula:C26H33N2O9PS2Forma y color:SolidPeso molecular:612.65α-Glucosidase-IN-8
CAS:α-Glucosidase-IN-8 (Compound 4k) is a potent, competitive inhibitor of α-glucosidase. It displays an impressive IC50 value of 0.18 μg/mL [1].Fórmula:C19H20FN3O2Forma y color:SolidPeso molecular:341.38Eggmanone
CAS:EGM1: potent PDE4D3 inhibitor, IC50=72 nM, 40-50x selectivity over other PDEs, activates PKA, blocks Hh.Fórmula:C20H20N2O2S3Forma y color:SolidPeso molecular:416.58hCAIX-IN-6
CAS:6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.Fórmula:C18H12N2O4SForma y color:SolidPeso molecular:352.36Carbonic anhydrase inhibitor 13
CAS:Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).Fórmula:C17H15N5O3S2Forma y color:SolidPeso molecular:401.46IDO1-IN-17
CAS:IDO1-IN-17 (I-4) is an IDO1 inhibitor, with an IC 50 of 0.44 μM in hela cells .Fórmula:C28H32BrClFN5O2Forma y color:SolidPeso molecular:604.94FAAH-IN-5
CAS:FAAH-IN-5 (Compound 7) selectively, irreversibly inhibits FAAH (IC50: 10.5 nM) with low PAMPA permeability.Fórmula:C21H19N3O6SForma y color:SolidPeso molecular:441.46IDH2R140Q-IN-1
CAS:IDH2R140Q-IN-1 is a potent inhibitor of IDH2R140Q (IC50: 6.1 nM) and can be used in studies of acute myeloid leukemia.Fórmula:C22H20F6N6Forma y color:SolidPeso molecular:482.42SHP2-IN-13
CAS:<p>SHP2-IN-13 is an orally active, highly selective allosteric inhibitor targeting the SHP2 “tunnel site,” exhibiting an IC50 of 83.0 nM.</p>Fórmula:C16H21N7OForma y color:SolidPeso molecular:327.38RORγt Inverse agonist 8
CAS:RORγt Inverse agonist 8 is a potent, selective, orally bioavailable RORγt inverse agonist(human RORγt-LBD with an IC50 of 19 nM).Fórmula:C26H33N7O2Pureza:98%Forma y color:SolidPeso molecular:475.59PKR activator 2
CAS:PKR activator 2 is a potent activator of pyruvate kinase-R (PKR).Fórmula:C18H16N8OSPureza:98%Forma y color:SolidPeso molecular:392.44CK2-IN-6
CAS:CK2-IN-6: Potent CK2 inhibitor for cancer, inflammation, pain, and immune research.Fórmula:C19H16ClN7O2Forma y color:SolidPeso molecular:409.83RORγt modulator 2
CAS:RORγt modulator 2 is a modulator of retinol-related orphan receptor γt (RORyt) (IC50<50 nM) and can be used in the study of RORγt-mediated diseases such as painFórmula:C28H29ClN2O4SForma y color:SolidPeso molecular:525.06KCN1
CAS:KCN1: a synthetic sulfonamide, nanomolar HIF inhibitor with preclinical anti-glioma and anti-pancreatic cancer effects.Fórmula:C26H27NO5SForma y color:SolidPeso molecular:465.56F-1394
CAS:F-1394 is an ACAT inhibitor that reduces atherosclerosis and neointimal thickening without changing serum cholesterol.Fórmula:C33H61N3O6Forma y color:SolidPeso molecular:595.85SCH-42354
CAS:SCH-42354: potent oral NEP inhibitor, activates ANP & leu-enkephalin, has anti-hypertensive properties, IC50s of 8.3 & 10.0 nM.Fórmula:C16H23NO3S2Forma y color:SolidPeso molecular:341.49ICI 211965
CAS:ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).Fórmula:C24H23NO2SPureza:98%Forma y color:SolidPeso molecular:389.51CM39
CAS:CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.Fórmula:C19H15FN4OSForma y color:SolidPeso molecular:366.41Oxythiamine diphosphate
CAS:Oxythiamine diphosphate is a competitivethiamine pyrophosphate inhibitor(Ki of 30 nM).Fórmula:C12H17N3O8P2SPureza:98%Forma y color:SolidPeso molecular:425.29(S)-Bromoenol lactone
CAS:(S)-BEL, a chiral inhibitor of iPLA2β, blocks vasopressin-induced arachidonate release in A10 cells; IC50 = 2μM.Fórmula:C16H13BrO2Forma y color:SolidPeso molecular:317.18PTP1B-IN-15
CAS:PTP1B-IN-15 is a potent and selective protein tyrosine phosphatase 1B (PTP1B) inhibitor that has shown research potential in type II diabetes and obesity.Fórmula:C19H17Br2NO5SForma y color:SolidPeso molecular:531.22Carbonic anhydrase inhibitor 11
CAS:Potent carbonic anhydrase inhibitor VI targets CA II, IX, XII with Ki: 40, 39, 900 nM respectively.Fórmula:C19H15F3N4O3S2Forma y color:SolidPeso molecular:468.47hCAIX/XII-IN-4
CAS:hCAIX/XII-IN-4 inhibits CAIX/XII with Ki: 4.5 nM (CAXII), 23.6 nM (CAIX), and >10000 nM (CAI/CAII).Fórmula:C20H16N2O5Forma y color:SolidPeso molecular:364.3511β-HSD1-IN-6
CAS:11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).Fórmula:C21H19ClN4OForma y color:SolidPeso molecular:378.86MB-07729
CAS:<p>MB-07729 inhibits fructose-1,6-bisphosphate with IC50: 189 nM (rat), 121 nM (monkey), 31 nM (human) for diabetes research.</p>Fórmula:C12H15N2O5PSPureza:99.54% - 99.64%Forma y color:SolidPeso molecular:330.3
