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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8628 productos de "Metabolismo"

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  • UCPH-102

    CAS:
    <p>UCPH-102: Selective EAAT1 inhibitor, IC50 0.43 μM, treats Alzheimer's, ALS, chronic pain, OCD; crosses blood-brain barrier, targets T-ALL cells.</p>
    Fórmula:C21H18N2O2
    Forma y color:Solid
    Peso molecular:330.38
  • Phenylpyropene C

    CAS:
    <p>Phenylpyropene C inhibits JAK/STAT and IFN-γ expression (IC50: 5.4-10.8 μM), also blocks acyl CoA (IC50: 16.0 μM).</p>
    Fórmula:C28H34O5
    Forma y color:Solid
    Peso molecular:450.57
  • ICMT-IN-36

    CAS:
    <p>ICMT-IN-36 (compound 40) serves as an ICMT inhibitor, with an IC50 value of 0.181 μM [1].</p>
    Fórmula:C21H25Cl2NO
    Forma y color:Solid
    Peso molecular:378.34
  • CM-10-18

    CAS:
    <p>CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.</p>
    Fórmula:C17H35NO5
    Forma y color:Solid
    Peso molecular:333.46
  • FM26

    CAS:
    FM26, an isoxazole-based RORγt inverse agonist, cuts EL4 IL-17a mRNA; potent with 264 nM IC50.
    Fórmula:C22H15ClF3N3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:461.82
  • 6β-hydroxy Testosterone

    CAS:
    <p>6β-hydroxy Testosterone (4-Androsten-6β,17β-diol-3-one) is a 17β-hydroxy steroid, an androgen and endogenous metabolite.</p>
    Fórmula:C19H28O3
    Forma y color:Soild
    Peso molecular:304.42
  • Dioleyldimethylammonium chloride

    CAS:
    <p>Dioleyldimethylammonium chloride (DODAC) is a cationic lipid utilized as a transfection reagent [1].</p>
    Fórmula:C38H76ClN
    Forma y color:Solid
    Peso molecular:582.47
  • ICMT-IN-19

    CAS:
    <p>ICMT-IN-19 (compound 53) serves as a potent inhibitor of ICMT, demonstrating an IC50 value of 0.026 μM [1].</p>
    Fórmula:C21H26N2O3
    Forma y color:Solid
    Peso molecular:354.44
  • AKB-6899

    CAS:
    <p>AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated</p>
    Fórmula:C14H11FN2O4
    Pureza:97.87%
    Forma y color:Solid
    Peso molecular:290.25
  • AMC Arachidonoyl Amide

    CAS:
    <p>Arachidonoyl amide (AMC-AA) is a fatty acid amide among several that serve to quantify fatty acid amide hydrolase (FAAH) activity. FAAH, with its relative lack of selectivity, processes various amide head groups beyond ethanolamine, the head group of its primary endogenous substrate, anandamide (AEA). The interaction of AMC-AA with FAAH leads to the liberation of fluorescent aminomethyl coumarin, which has an absorption peak at 360 nm and emission at 465 nm. This fluorescence release facilitates the rapid and efficient assessment of FAAH activity through the utilization of either a standard cuvette or a microplate fluorometer.</p>
    Fórmula:C30H39NO3
    Forma y color:Solid
    Peso molecular:461.6
  • LY-338979

    CAS:
    <p>LY-338979 is an impurity of pemetrexedone.</p>
    Fórmula:C20H21N5O7
    Pureza:98%
    Forma y color:Solid
    Peso molecular:443.41
  • PPAR agonist 1

    CAS:
    <p>PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.</p>
    Fórmula:C20H25NO6S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:407.48
  • PDE5-IN-2

    CAS:
    <p>PDE5-IN-2 is a potent, highly selective, and orally active inhibitor of PDE5(IC50 of 0.31 nM)</p>
    Fórmula:C25H21N3O6S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:491.52
  • Mal-Pc

    CAS:
    <p>Mal-Pc, a maleimide phthalocyanine, depletes GSH to reduce aggregation and boost ROS, improving PDT against cancer.</p>
    Fórmula:C46H28N10O8Si
    Pureza:98%
    Forma y color:Solid
    Peso molecular:876.86
  • Lp-PLA2-IN-13

    CAS:
    <p>Lp-PLA2-IN-13 (compound 15), a potent Lp-PLA2 inhibitor, holds potential for research in neurodegenerative-related diseases [1].</p>
    Fórmula:C22H17F5N4O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:496.39
  • L-690488

    CAS:
    <p>L-690488 has more effective cell penetration than L-690330. L-690488 is a prodrug of L-690330 and is a selective inositol monophosphatase (IMPase) inhibitor.</p>
    Fórmula:C32H52O16P2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:754.69
  • GLUT4 activator 1

    CAS:
    <p>GLUT4 activator 1 is a potent glucose transporter type 4 (GLUT4) translocation activator (EC50: 0.14 μM).</p>
    Fórmula:C23H21FN4O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:452.5
  • RORγt Inverse agonist 6

    CAS:
    <p>RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can be used in research on Th17-driven autoimmune diseases.</p>
    Fórmula:C28H29ClN6O5
    Pureza:99.52%
    Forma y color:Solid
    Peso molecular:565.02
  • S-Benzylglutathione

    CAS:
    <p>S-Benzylglutathione acts as a competitive inhibitor of glutathionase and undergoes conversion by rat kidney microsomes into its cysteine derivatives.</p>
    Fórmula:C17H23N3O6S
    Forma y color:Solid
    Peso molecular:397.45
  • Prostaglandin F2α-1-glyceryl ester

    CAS:
    <p>Prostaglandin F2α-1-glyceryl ester undergoes oxidation via 15-hydroxyprostaglandin dehydrogenase (15-HPGDH) [1].</p>
    Fórmula:C23H40O7
    Forma y color:Solid
    Peso molecular:428.566
  • Quizalofop-P

    CAS:
    <p>Quizalofop-P, a selective herbicide, is absorbed by weed stems and leaves before translocating both upward and downward within the plant, concentrating in</p>
    Fórmula:C17H13ClN2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:344.75
  • Benzyl-α-GalNAc

    CAS:
    <p>Benzyl-α-GalNAc (O-glycosylation-IN-1) is a potent inhibitor of O-glycosylation and is used to reduce mucin on cell surfaces.</p>
    Fórmula:C15H21NO6
    Pureza:99.84%
    Forma y color:Solid
    Peso molecular:311.33
  • DORI

    CAS:
    <p>DORI, a cationic lipid, efficiently delivers plasmid DNA in vitro, exhibiting lower cytotoxicity and high transfection efficiency [1].</p>
    Fórmula:C43H82BrNO5
    Forma y color:Solid
    Peso molecular:773.02
  • 1,2-Dilauroyl-sn-glycero-3-phospho-(2R)-glycerol sodium

    CAS:
    <p>1,2-Dilauroyl-sn-glycero-3-phospho-(2R)-glycerol is a type of phosphoglycerol characterized by the presence of lauric acid at the sn-1 and sn-2 positions. [Matreya, LLC. Catalog No. 1443]</p>
    Fórmula:C30H58O10PNa
    Forma y color:Solid
    Peso molecular:632.74
  • Safinamide Acid

    CAS:
    <p>Safinamide acid, a potential impurity in commercial safinamide preparations and a degradation product of safinamide under thermal and oxidative stress, is encountered in the pharmaceutical formulation process.</p>
    Fórmula:C17H18FNO3
    Forma y color:Solid
    Peso molecular:303.33
  • DNCA

    CAS:
    <p>DNCA, a neutral lipid, facilitates the creation of lipid nanoparticles (LNPs) and is instrumental in [nucleic acid delivery](1).</p>
    Fórmula:C45H82N4O4
    Forma y color:Solid
    Peso molecular:743.16
  • 3-Hydroxycarbofuran

    CAS:
    <p>3-Hydroxycarbofuran, a principal metabolite of Carbofuran, acts as a reversible inhibitor of acetylcholinesterase (AChE) [1].</p>
    Fórmula:C12H15NO4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:237.25
  • ICMT-IN-20

    CAS:
    <p>ICMT-IN-20 (compound 54) serves as an ICMT inhibitor with an IC50 value of 0.682 μM [1].</p>
    Fórmula:C21H26N2O3
    Forma y color:Solid
    Peso molecular:354.44
  • Frunexian

    CAS:
    <p>Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.</p>
    Fórmula:C19H26N4O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:374.43
  • h15-LOX-2 inhibitor 1

    CAS:
    <p>Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].</p>
    Fórmula:C17H13F3N2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:334.36
  • UK 357903

    CAS:
    <p>UK 357903, a phosphodiesterase 5A (PDE5A) inhibitor, is used potentially for the treatment of erectile dysfunction.</p>
    Fórmula:C27H34N8O5S
    Forma y color:Solid
    Peso molecular:582.67
  • RXPA 380

    CAS:
    <p>RXPA 380: C-terminal ACE inhibitor, Ki=3nM; IC50=2.5nM for C-domain ACE mutants.</p>
    Fórmula:C33H36N3O7P
    Forma y color:Solid
    Peso molecular:617.63
  • 1,2,3-Tritricosanoyl Glycerol

    CAS:
    <p>1,2,3-Tritricosanoyl glycerol, a triacylglycerol containing tricosanoic acid at the sn-1, sn-2, and sn-3 positions, serves as an internal standard for the quantification of fatty acids within the triglyceride component of human aortic endothelial cells (HAECs) cultured in media supplemented with stearic and/or oleic acid.</p>
    Fórmula:C72H140O6
    Forma y color:Solid
    Peso molecular:1101.88
  • A 79175

    CAS:
    <p>A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.</p>
    Fórmula:C15H13FN2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:304.27
  • Efipladib

    CAS:
    <p>Efipladib is a phospholipase inhibitor. Efipladib decreases nociceptive responses without affecting PGE2 levels in the cerebral spinal fluid.</p>
    Fórmula:C40H35Cl3N2O4S
    Forma y color:Solid
    Peso molecular:746.14
  • SCD1/5-IN-1

    CAS:
    <p>SCD1/5-IN-1 (Compound 10), a selective SCD1/5 inhibitor, is utilized in the research of neurological diseases [1].</p>
    Fórmula:C12H10N4O3
    Forma y color:Solid
    Peso molecular:258.237
  • GCase modulator-1

    CAS:
    <p>GCase Modulator-1 (Compound 9g), a quinazoline derivative, functions as a glucosidase modulator with an AC50 value of 2.23 µM [1].</p>
    Fórmula:C22H18N4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:338.41
  • ICMT-IN-27

    CAS:
    <p>ICMT-IN-27, also known as compound 64, is an inhibitor of the enzyme ICMT, demonstrating potent activity with an IC50 value of 0.1 µM [1].</p>
    Fórmula:C22H28FNO2
    Forma y color:Solid
    Peso molecular:357.46
  • FAAH/cPLA2α-IN-1

    CAS:
    <p>FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with half-maximal inhibitory concentrations (</p>
    Fórmula:C19H26N4O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:390.43
  • AS1468240

    CAS:
    <p>AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.</p>
    Fórmula:C25H25Cl2N5O3
    Forma y color:Solid
    Peso molecular:514.4
  • CETP-IN-3

    CAS:
    <p>CETP-IN-3 is an inhibitor of the plasma glycoprotein cholesterol ester transfer protein (CETP), elevating HDL-C through inhibition of CETP.</p>
    Fórmula:C30H24F12N2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:704.5
  • JNJ-42259152

    CAS:
    <p>JNJ-42259152 is a phosphodiesterase 10A PET tracer.</p>
    Fórmula:C24H23FN4O
    Forma y color:Solid
    Peso molecular:402.46
  • NC1

    CAS:
    <p>NC1 is a potent allosteric inhibitor of lymphoid-specific PTPN22, a protein tyrosine phosphatase.</p>
    Fórmula:C29H26N2O7S
    Forma y color:Solid
    Peso molecular:546.59
  • GLX481304

    CAS:
    <p>GLX481304 is a selective Nox-2 and Nox-4 inhibitor, exhibiting IC50 values of 1.25 μM.</p>
    Fórmula:C23H29N7O
    Forma y color:Solid
    Peso molecular:419.52
  • Inz-1

    CAS:
    Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.
    Fórmula:C16H14N2O2
    Pureza:99.55% - 99.88%
    Forma y color:Solid
    Peso molecular:266.29
  • PD 109488

    CAS:
    <p>PD 109488 is a metabolite of quinapril and is a derivative of Quinapril that acts as an ACE inhibitor.</p>
    Fórmula:C25H28N2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:420.5
  • G1-OC2-K3-E10

    CAS:
    <p>G1-OC2-K3-E10, an ionizable lipid, facilitates mRNA delivery through lipid nanoparticles (LNPs) [1].</p>
    Fórmula:C54H111N5O7
    Forma y color:Solid
    Peso molecular:942.49
  • Anticancer agent 144

    CAS:
    <p>Compound 144 (also known as Anticancer Agent 144) is a potent inhibitor of both PTPN2 and PTP1B, exhibiting IC50 values of less than 2.5 nM, making it suitable</p>
    Fórmula:C19H15BrF2N3O6PS2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:594.34
  • 11-Hexadecenoic Acid

    CAS:
    <p>11-Hexadecenoic acid, a monounsaturated fatty acid, comprises both 11-cis-hexadecenoic acid and 11-trans-hexadecenoic acid. These isoforms are present in ewe milk fat and their concentrations increase when the diet is supplemented with lipids from linseed, sunflower, olive, or fish oils. Additionally, 11-trans-hexadecenoic acid is found in intramuscular fat of both male and female foals. The product is a blend of the 11-cis and 11-trans forms. [Matreya, LLC. Catalog No. 1208]</p>
    Fórmula:C16H30O2
    Forma y color:Solid
    Peso molecular:254.41
  • Biliverdin

    CAS:
    <p>Biliverdin, produced through the oxidation of bilirubin, can also be synthesized through a non-protoporphyrin pathway in Corynebacterium glutamicum [1].</p>
    Fórmula:C33H34N4O6
    Forma y color:Solid
    Peso molecular:582.65