Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(271 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(98 productos)
- Lípido(58 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(165 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8628 productos de "Metabolismo"
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Dieicosanoin
CAS:<p>Dieicosanoin is a diacylglycerol that incorporates arachidic acid, a saturated long-chain fatty acid featuring a 20-carbon backbone. This acid is derivable from sources such as peanut butter and anaerobic fungi [1] [2].</p>Fórmula:C43H84O5Forma y color:SolidPeso molecular:681.12 (Monomer)ATX inhibitor 15
CAS:<p>ATX inhibitor 15, an indole-based carbamate, has a 2.17 nM IC50 against ATX, suppresses pro-fibrotic genes, and protects against mouse lung fibrosis.</p>Fórmula:C27H32ClN5O4SForma y color:SolidPeso molecular:558.09ICMT-IN-8
CAS:<p>ICMT-IN-8 (compound 30) serves as an inhibitor of ICMT, exhibiting an IC50 value of 0.652 μM [1].</p>Fórmula:C23H31NO3Forma y color:SolidPeso molecular:369.5Dendrogenin A
CAS:<p>Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic</p>Fórmula:C32H55N3O2Forma y color:SolidPeso molecular:513.80Mitochondria degrader-1
CAS:<p>Mitochondria degrader-1, a potent autophagy inducer, aids in neurodegenerative, cancer, and aging disease research.</p>Fórmula:C33H49ClFN7O8SForma y color:SolidPeso molecular:758.3H2-003
CAS:<p>H2-003 is a selective inhibitor of diacylglycerol acyltransferase 2 (DGAT2).</p>Fórmula:C25H26N4O4Forma y color:SolidPeso molecular:446.5ICMT-IN-25
CAS:<p>ICMT-IN-25 (compound 37) serves as a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.025 μM [1].</p>Fórmula:C21H26ClNOForma y color:SolidPeso molecular:343.89AZD7687
CAS:<p>AZD7687: Selective DGAT1 inhibitor, IC50 of 80 nM. In vitro reduces postprandial TAG. In vivo significant GI side effects at >5 mg/day dose.</p>Fórmula:C21H25N3O3Forma y color:SolidPeso molecular:367.449-OxoODE
CAS:<p>9-OxoODE, formed through the oxidation of the allylic hydroxyl group in both 9(S)-HODE and 9(R)-HODE, is present in rabbit reticulocyte plasma and mitochondrial membranes as both 9- and 13-oxoODEs, constituting approximately 2% of the total linoleate residues. The majority of these oxidized linoleate residues are esterified to membrane lipids.</p>Fórmula:C18H30O3Forma y color:SolidPeso molecular:294.4Bemoradan
CAS:<p>Bemoradan is an inhibitor of the rolipram-insensitive cyclic AMP phosphodiesterase from canine heart tissue</p>Fórmula:C13H13N3O3Forma y color:SolidPeso molecular:259.26Monoacylglycerol lipase inhibitor 1
CAS:<p>Monoacylglycerol lipase inhibitor 1, also known as compound 13 [1], is a potent inhibitor of monoacylglycerol lipase.</p>Fórmula:C21H28N2O3Forma y color:SolidPeso molecular:356.46S-2E
CAS:<p>S-2E, an oral inhibitor of HMG-CoA reductase/acetyl-CoA carboxylase, treats hyperlipidemia.</p>Fórmula:C22H25NO4Forma y color:SolidPeso molecular:367.44GLX481304
CAS:<p>GLX481304 is a selective Nox-2 and Nox-4 inhibitor, exhibiting IC50 values of 1.25 μM.</p>Fórmula:C23H29N7OForma y color:SolidPeso molecular:419.52DHODH-IN-22
CAS:<p>DHODH-IN-22: potent, selective DHODH inhibitor, orally active, IC50: 0.3 nM, for AML research.</p>Fórmula:C21H21ClF4N6O5Forma y color:SolidPeso molecular:548.88Edaglitazone
CAS:<p>Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.</p>Fórmula:C24H20N2O4S2Pureza:98%Forma y color:SolidPeso molecular:464.56Quizalofop-P
CAS:<p>Quizalofop-P, a selective herbicide, is absorbed by weed stems and leaves before translocating both upward and downward within the plant, concentrating in</p>Fórmula:C17H13ClN2O4Pureza:98%Forma y color:SolidPeso molecular:344.75Glyoxalase I inhibitor 3
CAS:<p>Compound 22g: potent GLO1 inhibitor; IC50=0.011 μM; potential for depression, anxiety research.</p>Fórmula:C22H21N3O3Forma y color:SolidPeso molecular:375.42(S)-(-)-Bay-K-8644
CAS:<p>(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.</p>Fórmula:C16H15F3N2O4Pureza:98.28% - 99.37%Forma y color:SolidPeso molecular:356.3sPLA2 inhibitor 1
CAS:<p>KH064 is a sPLA2-IIA inhibitor of oral activity.</p>Fórmula:C31H37NO4Forma y color:SolidPeso molecular:487.63PHD-IN-2
CAS:<p>PHD-IN-2 (Compound 91), a potent PHD antagonist with an IC50 of less than 5 nM, effectively stimulates erythropoietin synthesis in HEP3B cells with an EC50 of</p>Fórmula:C26H27N7O4Pureza:98%Forma y color:SolidPeso molecular:501.54CAY10502
CAS:<p>CAY10502 inhibits cPLA2α (85 kDa), crucial in inflammation/arachidonic cascade, with 4.3 nM IC50, reducing arachidonic acid in human platelets.</p>Fórmula:C30H37NO7Forma y color:SolidPeso molecular:523.62Ilepatril
CAS:<p>Ilepatril, also known as AVE-7688, is a vasopeptidase inhibitor for the treatment of hypertension.</p>Fórmula:C22H28N2O5SForma y color:SolidPeso molecular:432.53BMS-795311
CAS:<p>Potent CETP inhibitor, boosts HDL-C levels, orally active; IC50=4nM.</p>Fórmula:C33H23F10NO3Forma y color:SolidPeso molecular:671.521-Stearoyl-2-hydroxy-sn-glycero-3-PG sodium
CAS:<p>1-Stearoyl-2-hydroxy-sn-glycero-3-PG, a lysophospholipid characterized by the presence of stearic acid (18:0) at the sn-1 position, finds application in the creation of micelles, liposomes, and various artificial membranes, including those utilized in lipid-based drug delivery systems.</p>Fórmula:C24H48NaO9PForma y color:SolidPeso molecular:534.60315-PGDH-IN-2
CAS:<p>15-PGDH-IN-2 (Compound 2) is an inhibitor of 15-PGDH with an IC50 value of 0.274 nM. This compound is useful for research into hair loss, bone formation, gastric ulcer healing, and dermal wound healing [1].</p>Fórmula:C16H13NO3S2Forma y color:SolidPeso molecular:331.411-Linoleoyl-3-α-Linolenoyl-rac-glycerol
CAS:<p>1-Linoleoyl-3-α-linolenoyl-rac-glycerol, a diacylglycerol, features linoleic acid at the sn-1 position and α-linolenic acid at the sn-3 position. This compound is identified in olive oil that has undergone lipase-catalyzed glycerolysis, utilizing immobilized lipase B derived from C. antarctica.</p>Fórmula:C39H66O5Forma y color:SolidPeso molecular:614.94N-Methyl Palbociclib
CAS:<p>N-Methyl Palbociclib is an impurity of the orally active selective CDK4 and CDK6 inhibitor Palbociclib (PD 0332991).</p>Fórmula:C25H31N7O2Pureza:98%Forma y color:SolidPeso molecular:461.56hMAO-B-IN-32
CAS:<p>hMAO-B-IN-32 is a potent hMAO-B selective inhibitor with an IC50 of 45.52 μM.</p>Fórmula:C16H19NO4Pureza:99.65%Forma y color:SolidPeso molecular:289.33BMS-962212
CAS:<p>BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.</p>Fórmula:C32H28ClFN8O5Pureza:98%Forma y color:SolidPeso molecular:659.074′-DTMP
CAS:<p>4′-DTMP (4-Demethyltrimethoprim) is a DHFR inhibitor with antimicrobial activity against Escherichia coli.</p>Fórmula:C13H16N4O3Pureza:98%Forma y color:SolidPeso molecular:276.29Sulforhodamine 101 DHPE
CAS:<p>Sulforhodamine 101 DHPE, a fluorescent probe, results from the conjugation of sulforhodamine 101, a red fluorescent dye with excitation/emission spectra of 586/605 nm, to the phospholipid 1,2-dipalmitoyl-sn-glycero-3-PE. It effectively integrates into phospholipid bilayers and is utilized for imaging solid supported lipid bilayers, detecting protein-ligand interactions on bilayers, and monitoring lipid probe colocalization in liposomes through resonance energy transfer (RET).</p>Fórmula:C74H117N4O14PS2Forma y color:SolidPeso molecular:1381.86sEH/AChE-IN-4
CAS:<p>sEH/AChE-IN-4-15 is a dual sEH and AChE inhibitor crossing the BBB, with IC50s: 3.1 nM (hsEH), 1660 nM (hAChE), 179 nM (hBChE), 14.5 nM (msEH), 102 nM (mAChE).</p>Fórmula:C35H39ClF3N5O3Forma y color:SolidPeso molecular:670.16AR453588 hydrochloride
CAS:<p>AR453588 hydrochloride is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.</p>Fórmula:C25H26ClN7O2S2Pureza:98%Forma y color:SolidPeso molecular:556.1BMS-654457
CAS:<p>BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).</p>Fórmula:C36H37N5O4Pureza:98%Forma y color:SolidPeso molecular:603.715-Lipoxygenase-In-1
CAS:5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.Fórmula:C23H28N4O2SForma y color:SolidPeso molecular:424.56EMD638683 R-Form
CAS:<p>EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. EMD638683 R-Form is the R-form of EMD638683.</p>Fórmula:C18H18F2N2O4Forma y color:SolidPeso molecular:364.34XL041
CAS:<p>XL041 (BMS-852927) is an agonist of LXRβ-selective.</p>Fórmula:C29H28Cl2F2N2O4SPureza:98%Forma y color:SolidPeso molecular:609.51RB 101
CAS:<p>RB 101 suppresses enkephalinase and aminopeptidases; biologically cleaved at disulfide to produce inhibitors of both aminopeptidase N and neutral endopeptidase.</p>Fórmula:C31H38N2O3S3Pureza:98%Forma y color:SolidPeso molecular:582.84ICMT-IN-36
CAS:<p>ICMT-IN-36 (compound 40) serves as an ICMT inhibitor, with an IC50 value of 0.181 μM [1].</p>Fórmula:C21H25Cl2NOForma y color:SolidPeso molecular:378.34MLS000545091
CAS:<p>MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.</p>Fórmula:C14H15ClN2OPureza:99.84%Forma y color:SolidPeso molecular:262.73SHP2-IN-18
CAS:<p>SHP2-IN-18 (compound 183) is a potent SHP2 inhibitor, exhibiting an IC50 of 3 nM and applicable to glioblastoma research [1].</p>Fórmula:C26H27FN6Forma y color:SolidPeso molecular:442.531-Palmitoyl-2-Oleoyl-3-Stearoyl-rac-glycerol
CAS:<p>1-Palmitoyl-2-oleoyl-3-stearoyl-rac-glycerol, a primary triacylglycerol in cocoa butter, features palmitic acid (at the sn-1 position), oleic acid (at the sn-2 position), and stearic acid (at the sn-3 position).</p>Fórmula:C55H104O6Forma y color:SolidPeso molecular:861.41ICMT-IN-31
CAS:<p>ICMT-IN-31 (compound 68) serves as an ICMT inhibitor, demonstrating significant potency with an IC50 value of 0.0038 μM [1].</p>Fórmula:C19H24ClNOSForma y color:SolidPeso molecular:349.92113-O16B
CAS:<p>113-O16B, an ionizable cationic lipidoid featuring a disulfide bond, is utilized in producing lipid nanoparticles (LNPs) for mRNA delivery [1].</p>Fórmula:C73H143N3O8S8Forma y color:SolidPeso molecular:1447.455,6-dehydro Arachidonic Acid
CAS:<p>5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.</p>Fórmula:C20H30O2Forma y color:SolidPeso molecular:302.45ICMT-IN-12
CAS:<p>ICMT-IN-12 (compound 78) serves as an ICMT inhibitor, demonstrating an IC50 value of 0.42 μM [1].</p>Fórmula:C24H33NOSForma y color:SolidPeso molecular:383.59ICMT-IN-50
CAS:<p>ICMT-IN-50 (compound 3) serves as an inhibitor of ICMT with an IC50 value of 0.31 µM [1].</p>Fórmula:C27H31NO3Forma y color:SolidPeso molecular:417.54C2 Dihydro Ceramide (d18:0/2:0)
CAS:<p>C2 Dihydro Ceramide (d18:0/2:0) (C2 Dihydroceramide) is a ceramide that is a precursor of ceramide synthesis and stimulates ABCA1-mediated cholesterol efflux.</p>Fórmula:C20H41NO3Pureza:98%Forma y color:SolidPeso molecular:343.54α-Glucosidase-IN-29
CAS:<p>α-Glucosidase-IN-29 (compound 19) is an inhibitor of α-glucosidases, exhibiting an IC50 value of 1.21 μM and a Ki of 1.80 μM.</p>Fórmula:C33H30Br2O7Pureza:98%Forma y color:SolidPeso molecular:698.4UK-157147
CAS:<p>UK-157147 is a substrate for UGT1A1(Km: 105 μM).</p>Fórmula:C23H24N2O7SPureza:98%Forma y color:SolidPeso molecular:472.51
