Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(271 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(98 productos)
- Lípido(58 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(165 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
Mostrar 34 subcategorías más
Se han encontrado 8628 productos de "Metabolismo"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Niraxostat
CAS:<p>Niraxostat (Y-700) is one of the isocytosine derivatives as xanthine oxidase inhibitors.</p>Fórmula:C16H17N3O3Pureza:98.13%Forma y color:SolidPeso molecular:299.32AZD-1656
CAS:AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2Fórmula:C24H26N6O5Pureza:97.07% - 99.37%Forma y color:SolidPeso molecular:478.58-Hydroxyguanine hydrochloride
CAS:<p>8-Hydroxyguanine, generated through the oxidative degradation of DNA by the hydroxyl radical, serves as an indicator of oxidative stress in biological systems.</p>Fórmula:C5H5N5O2HClForma y color:SolidPeso molecular:203.62-Myristyldistearin
CAS:<p>2-Myristyldistearin (SMS), a triacylglycerol comprising myristic acid and stearic acid [1], showcases its intricate structural composition.</p>Fórmula:C53H102O6Forma y color:SolidPeso molecular:835.37Gisadenafil
CAS:<p>Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.</p>Fórmula:C23H33N7O5SPureza:98.82% - 99.50%Forma y color:SolidPeso molecular:519.62hCAIX-IN-15
CAS:<p>hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer</p>Fórmula:C18H14FN7O2SPureza:98%Forma y color:SolidPeso molecular:411.41α-Glucosidase-IN-28
CAS:<p>α-Glucosidase-IN-28 (Compound 18) is an α-glucosidase inhibitor with an IC50 of 0.62 μM and Ki value of 3.93 μM.</p>Fórmula:C29H22Br2O7Pureza:98%Forma y color:SolidPeso molecular:642.29AZD-6605
CAS:<p>AZD6605 is a potent, reversible inhibitor of, MMP2, MMP9, MMP12 and MMP13.</p>Fórmula:C18H21F4N3O6SForma y color:SolidPeso molecular:483.43SH-BC-893
CAS:<p>SH-BC-893: Oral anti-cancer sphingolipid analog, prevents ceramide-related mitochondrial issues, and tackles diet-related obesity.</p>Fórmula:C19H32ClNOForma y color:SolidPeso molecular:325.92KCL-286
CAS:KCL-286 is an available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).Fórmula:C19H14N2O4Pureza:99.93%Forma y color:SolidPeso molecular:334.33Prostaglandin F2α-1-glyceryl ester
CAS:<p>Prostaglandin F2α-1-glyceryl ester undergoes oxidation via 15-hydroxyprostaglandin dehydrogenase (15-HPGDH) [1].</p>Fórmula:C23H40O7Forma y color:SolidPeso molecular:428.566hCAIX/XII-IN-8
CAS:<p>hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.</p>Fórmula:C16H13Cl2N5O3SPureza:98%Forma y color:SolidPeso molecular:426.28Cav 3.2 inhibitor 4
CAS:<p>Cav 3.2 Inhibitor 4 (Compound 21) is a selective and potent inhibitor of the T-type calcium channel (Ca v 3.2), demonstrating peripheral restriction with an</p>Fórmula:C21H32Cl2N4O3Pureza:98%Forma y color:SolidPeso molecular:459.41(Rac)-Lonafarnib
CAS:<p>(Rac)-Lonafarnib is a racemic FTase inhibitor, effective against H-ras, K-ras, N-ras (IC50: 1.9, 5.2, 2.8 nM), and has anti-HDV properties.</p>Fórmula:C27H31Br2ClN4O2Forma y color:SolidPeso molecular:638.82BMS-654457
CAS:<p>BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).</p>Fórmula:C36H37N5O4Pureza:98%Forma y color:SolidPeso molecular:603.711-Linoleoyl-3-α-Linolenoyl-rac-glycerol
CAS:<p>1-Linoleoyl-3-α-linolenoyl-rac-glycerol, a diacylglycerol, features linoleic acid at the sn-1 position and α-linolenic acid at the sn-3 position. This compound is identified in olive oil that has undergone lipase-catalyzed glycerolysis, utilizing immobilized lipase B derived from C. antarctica.</p>Fórmula:C39H66O5Forma y color:SolidPeso molecular:614.94RXPA 380
CAS:<p>RXPA 380: C-terminal ACE inhibitor, Ki=3nM; IC50=2.5nM for C-domain ACE mutants.</p>Fórmula:C33H36N3O7PForma y color:SolidPeso molecular:617.63AS 183
CAS:<p>AS 183 is an inhibitor of cholesterol acyltransferase (ACAT).</p>Fórmula:C19H34O3Forma y color:SolidPeso molecular:310.47AR453588 hydrochloride
CAS:<p>AR453588 hydrochloride is an orally bioavailable anti-diabetic glucokinase activator (EC50: 42 nM) with anti-hyperglycemic activity.</p>Fórmula:C25H26ClN7O2S2Pureza:98%Forma y color:SolidPeso molecular:556.1Kelatorphan
CAS:<p>Kelatorphan is an enkephalin degrading enzyme full inhibitor.</p>Fórmula:C14H18N2O5Pureza:98%Forma y color:SolidPeso molecular:294.3244cis
CAS:<p>244cis, an ionizable cationic lipid incorporating a piperazine structure, facilitates the creation of lipid nanoparticles (LNPs). These LNPs, when formulated with 244cis and coated with an mRNA reporter gene, exhibit preferential accumulation in the lungs of mice, in contrast to those formulated with SM-102. Additionally, it leads to a reduction in the levels of serum chemokine (C-C motif) ligand 2 (CCL2) [1].</p>Fórmula:C60H111N3O6Forma y color:SolidPeso molecular:970.54Diethyl-pythiDC
CAS:<p>Diethyl-pythiDC is an collagen prolyl 4-hydroxylase inhibitor.</p>Fórmula:C14H14N2O4SPureza:99.98%Forma y color:SolidPeso molecular:306.34CM-10-18
CAS:<p>CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.</p>Fórmula:C17H35NO5Forma y color:SolidPeso molecular:333.46Lp-PLA2-IN-9
CAS:<p>Lp-PLA2-IN-9, a tetracyclic pyrimidinone, inhibits rhLp-PLA2 (pIC50: 10.1), promising for neurodegenerative research.</p>Fórmula:C25H19ClF5N3O4Forma y color:SolidPeso molecular:555.88IDH1 Inhibitor 2
CAS:<p>IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).</p>Fórmula:C26H22N4OPureza:98%Forma y color:SolidPeso molecular:406.48BMS-962212
CAS:<p>BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.</p>Fórmula:C32H28ClFN8O5Pureza:98%Forma y color:SolidPeso molecular:659.07cis-ent-Tadalafil
CAS:<p>cis-ent-Tadalafil (cis-ent-IC-351) is a potent and selective PDE5 inhibitor that lowers blood pressure.</p>Fórmula:C22H19N3O4Pureza:99.86%Forma y color:SolidPeso molecular:389.4HIF-2α-IN-6
CAS:<p>HIF-2α-IN-6 (117) is a HIF-2α inhibitor [1].</p>Fórmula:C15H13F4NO3SForma y color:SolidPeso molecular:363.33ICMT-IN-20
CAS:<p>ICMT-IN-20 (compound 54) serves as an ICMT inhibitor with an IC50 value of 0.682 μM [1].</p>Fórmula:C21H26N2O3Forma y color:SolidPeso molecular:354.44ICMT-IN-9
CAS:<p>ICMT-IN-9 (compound 47) is a potent ICMT inhibitor with an IC50 value of 0.16 μM [1].</p>Fórmula:C22H28FNO2Forma y color:SolidPeso molecular:357.46ICMT-IN-46
CAS:<p>ICMT-IN-46 (compound 25) is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting an IC50 value of 0.556 μM [1].</p>Fórmula:C25H35NOForma y color:SolidPeso molecular:365.55S-2E
CAS:<p>S-2E, an oral inhibitor of HMG-CoA reductase/acetyl-CoA carboxylase, treats hyperlipidemia.</p>Fórmula:C22H25NO4Forma y color:SolidPeso molecular:367.44NTE-122
CAS:<p>NTE-122 is a competitive Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor.</p>Fórmula:C38H59ClN6O2Pureza:98%Forma y color:SolidPeso molecular:667.38CKD-519
CAS:<p>CKD-519: A CETP inhibitor with an IC50 of 2.3 nM, blocking cholesteryl ester transfer in serum.</p>Fórmula:C31H34F7NO3Forma y color:SolidPeso molecular:601.6CYP17-IN-1
CAS:<p>CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.</p>Fórmula:C18H17FN2SPureza:99.14% - 99.83%Forma y color:SolidPeso molecular:312.4SHP2-IN-17
CAS:<p>SHP2-IN-17 (compound 192) is a potent inhibitor of SHP2, exhibiting an IC50 of 2 nM and holds potential for use in glioblastoma research [1].</p>Fórmula:C25H24Cl2N6Forma y color:SolidPeso molecular:479.43-Hydroxycarbofuran
CAS:<p>3-Hydroxycarbofuran, a principal metabolite of Carbofuran, acts as a reversible inhibitor of acetylcholinesterase (AChE) [1].</p>Fórmula:C12H15NO4Pureza:98%Forma y color:SolidPeso molecular:237.25SMS1-IN-1
CAS:<p>SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies.</p>Fórmula:C23H23BrN2O4SPureza:99.81%Forma y color:SolidPeso molecular:503.415,6-dehydro Arachidonic Acid
CAS:<p>5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.</p>Fórmula:C20H30O2Forma y color:SolidPeso molecular:302.453-Oxo-5β-cholanoic acid
CAS:<p>3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid) (Dehydrolithocholic acid) is a bile acid metabolite and inhibits the differentiation of TH17 cells by directly</p>Fórmula:C24H38O3Pureza:98.01% - 99.86%Forma y color:SolidPeso molecular:374.56RB 101
CAS:<p>RB 101 suppresses enkephalinase and aminopeptidases; biologically cleaved at disulfide to produce inhibitors of both aminopeptidase N and neutral endopeptidase.</p>Fórmula:C31H38N2O3S3Pureza:98%Forma y color:SolidPeso molecular:582.84(S)-(-)-Bay-K-8644
CAS:<p>(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.</p>Fórmula:C16H15F3N2O4Pureza:98.28% - 99.37%Forma y color:SolidPeso molecular:356.31,2-Dioleoyl-3-Stearoyl-rac-glycerol
CAS:<p>1,2-Dioleoyl-3-stearoyl-rac-glycerol, a triacylglycerol, features oleic acid at the sn-1 and sn-2 positions and stearic acid at the sn-3 position. This compound is present in sunflower, corn, and soybean oils, as well as in ostrich oil.</p>Fórmula:C57H106O6Forma y color:SolidPeso molecular:887.45GNE-618
CAS:<p>GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM).</p>Fórmula:C21H15F3N4O3SForma y color:SolidPeso molecular:460.43ICMT-IN-5
CAS:<p>ICMT-IN-5 (compound 46) is an ICMT inhibitor with an IC50 value of 0.3 μM [1].</p>Fórmula:C22H28FNOForma y color:SolidPeso molecular:341.46AA 863
CAS:<p>AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.</p>Fórmula:C21H26O5Pureza:98%Forma y color:SolidPeso molecular:358.43MT-3014
CAS:<p>MT-3014: Strong, selective brain-penetrating PDE 10A inhibitor; IC50 0.062 nM (human), 0.09 nM (bovine).</p>Fórmula:C23H25F2N7OPureza:98%Forma y color:SolidPeso molecular:453.49XL041
CAS:<p>XL041 (BMS-852927) is an agonist of LXRβ-selective.</p>Fórmula:C29H28Cl2F2N2O4SPureza:98%Forma y color:SolidPeso molecular:609.51Monoacylglycerol lipase inhibitor 1
CAS:<p>Monoacylglycerol lipase inhibitor 1, also known as compound 13 [1], is a potent inhibitor of monoacylglycerol lipase.</p>Fórmula:C21H28N2O3Forma y color:SolidPeso molecular:356.46(R)-IDO/TDO-IN-1
CAS:<p>(R)-IDO/TDO-IN-1 (compound 25), an indoleamine-2,3-dioxygenase (IDO) inhibitor, demonstrates good pharmacokinetic properties and exerts anti-tumor effects in the MC38 xenograft model. This compound exhibits synergy when combined with the anti-PD-1 monoclonal antibody (SHR-1210) [1].</p>Fórmula:C25H24FN5Forma y color:SolidPeso molecular:413.49
