Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(270 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(97 productos)
- Lípido(59 productos)
- Lipoxigenasa(125 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8626 productos de "Metabolismo"
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C12-113
CAS:<p>C12-113, a lipidoid delivery agent, effectively transfects siRNA into cells and, when combined with additional lipids, forms lipid nanoparticles (LNPs). These LNPs facilitate the delivery of mRNA encoding the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in mice [1] [2].</p>Fórmula:C53H111N3O4Forma y color:SolidPeso molecular:854.47cis-8-Octadecenoic Acid
CAS:<p>Cis-8-Octadecenoic acid, a monounsaturated fatty acid and isomer of oleic acid, trans-vaccenic acid, trans-petroselinic acid, and cis-petroselinic acid, is present in partially hydrogenated vegetable oil and milk fat.</p>Fórmula:C18H34O2Forma y color:SolidPeso molecular:282.46h-NTPDase-IN-5
CAS:<p>h-NTPDase-IN-5 (compound 3b) serves as a pan-inhibitor of NTPDase, exhibiting inhibitory concentration 50 (IC50) values of 1.10 μM (h-NTPDase1), 44.73 μM (h-</p>Fórmula:C23H21N3O2SPureza:98%Forma y color:SolidPeso molecular:403.511-dehydro Thromboxane B3
CAS:<p>11-Dehydro Thromboxane B3 (11-dehydro TXB3) serves as a urinary metabolite of TXA3 in humans following an increased dietary intake of EPA.</p>Fórmula:C20H30O6Forma y color:SolidPeso molecular:366.5AZD 4017
CAS:<p>AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).</p>Fórmula:C22H33N3O3SPureza:99.61%Forma y color:SolidPeso molecular:419.58FM26
CAS:FM26, an isoxazole-based RORγt inverse agonist, cuts EL4 IL-17a mRNA; potent with 264 nM IC50.Fórmula:C22H15ClF3N3O3Pureza:98%Forma y color:SolidPeso molecular:461.82Cholesterol 24-hydroxylase-IN-2
CAS:<p>Cholesterol 24-hydroxylase-IN-2 is a potent inhibitor of cholesterol 24-hydroxylase (CH24H or CYP46A1), exhibiting an IC50 value of 5.4 nM, and has potential</p>Fórmula:C20H23FN4OForma y color:SolidPeso molecular:354.42HIF-2α-IN-9
CAS:<p>HIF-2α-IN-9 (compound 35r) serves as an HIF-2α inhibitor, effectively suppressing VEGF-A with an IC50 of 305 nM, and modulating growth-promoting genes within</p>Fórmula:C12H13F5O4S2Pureza:98%Forma y color:SolidPeso molecular:380.35Monoacylglycerol lipase inhibitor 1
CAS:<p>Monoacylglycerol lipase inhibitor 1, also known as compound 13 [1], is a potent inhibitor of monoacylglycerol lipase.</p>Fórmula:C21H28N2O3Forma y color:SolidPeso molecular:356.46AZD1092
CAS:<p>AZD1092 is the glucokinase enzyme activator.</p>Fórmula:C24H26N4O5Pureza:98%Forma y color:SolidPeso molecular:450.49Desacetyl bisacodyl
CAS:<p>Desacetyl bisacodyl, the active metabolite of the laxative bisacodyl, evokes epithelial Cl(-) secretion in the rat colon and rectum, in addition to increasing</p>Fórmula:C18H15NO2Pureza:98%Forma y color:SolidPeso molecular:277.32DPM-1001 trihydrochloride
<p>DPM-1001 trihydrochloride: Potent PTP1B inhibitor, IC50 100 nM, oral, non-competitive, anti-diabetic.</p>Fórmula:C35H60Cl3N3O3Forma y color:SolidPeso molecular:677.23Methyl γ-Linolenyl Fluorophosphonate
CAS:<p>MγLnFP, an analog of methyl arachidonyl fluozophosphonate (MAFP), holds significance in pharmacological research due to its potential as an inhibitor of phospholipases, FAAH, and its role as a CB receptor ligand. However, the properties and effects of the γ-linolenyl variant of MAFP remain to be fully explored.</p>Fórmula:C19H34FO2PForma y color:SolidPeso molecular:344.451ICMT-IN-28
CAS:<p>ICMT-IN-28 (compound 65) serves as an inhibitor of ICMT, exhibiting significant potency with an IC50 value of 0.008 μM [1].</p>Fórmula:C22H28FNO2Forma y color:SolidPeso molecular:357.46Quetiapine sulfoxide dihydrochloride
CAS:<p>Quetiapine sulfoxide dihydrochloride, a major metabolite of second-gen antipsychotic Quetiapine, modulates 5-HT and dopamine receptors.</p>Fórmula:C21H27Cl2N3O3SPureza:98%Forma y color:SolidPeso molecular:472.43Hemipyocyanine
CAS:<p>Hemipyocyanine (528-71-2) is the virulence factor of Gram-negative, aerobic rod bacterium Pseudomonas aeruginosa. Hemipyocyanine is an α-Amylase inhibitor.</p>Fórmula:C12H8N2OPureza:99.02% - 99.75%Forma y color:SolidPeso molecular:196.25J-4
CAS:<p>5J-4 is a potent a blocker of calcium release-activated calcium (CRAC) channel and store-operated calcium entry (SOCE).</p>Fórmula:C16H12N2O3SPureza:96.12%Forma y color:SolidPeso molecular:312.34113-O16B
CAS:<p>113-O16B, an ionizable cationic lipidoid featuring a disulfide bond, is utilized in producing lipid nanoparticles (LNPs) for mRNA delivery [1].</p>Fórmula:C73H143N3O8S8Forma y color:SolidPeso molecular:1447.45PDE5-IN-42
CAS:<p>PDE5-IN-42 is a selective inhibitor of second-generation phosphodiesterase type 5 (PDE5).</p>Fórmula:C23H31N7O3Pureza:98%Forma y color:SolidPeso molecular:453.54Glycolithocholic acid
CAS:<p>Glycolithocholic acid (Lithocholic acid glycine conjugate) is a glycine conjugate of lithocholic acid.</p>Fórmula:C26H43NO4Pureza:99.75%Forma y color:SolidPeso molecular:433.62Difamilast
CAS:<p>Difamilast is a selective inhibitor of phosphodiesterase-4 (PDE4) with particularly efficient inhibition of subtype B (IC50=11.2 nM).</p>Fórmula:C23H24F2N2O5Pureza:99.64%Forma y color:SolidPeso molecular:446.44PPAR agonist 1
CAS:<p>PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.</p>Fórmula:C20H25NO6SPureza:98%Forma y color:SolidPeso molecular:407.48Glyoxalase I inhibitor 3
CAS:<p>Compound 22g: potent GLO1 inhibitor; IC50=0.011 μM; potential for depression, anxiety research.</p>Fórmula:C22H21N3O3Forma y color:SolidPeso molecular:375.42AA 863
CAS:<p>AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.</p>Fórmula:C21H26O5Pureza:98%Forma y color:SolidPeso molecular:358.43FASN-IN-1
CAS:<p>FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme</p>Fórmula:C18H25N3O3S2Pureza:99.92% - >99.99%Forma y color:SolidPeso molecular:395.54Quetiapine sulfoxide hydrochloride
<p>Quetiapine sulfoxide hydrochloride is a main metabolite of Quetiapinem. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist.</p>Fórmula:C21H26ClN3O3SPureza:98%Forma y color:SolidPeso molecular:435.97AKB-6899
CAS:<p>AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated</p>Fórmula:C14H11FN2O4Pureza:97.87%Forma y color:SolidPeso molecular:290.25PDE7-IN-3
CAS:<p>PDE7-IN-3 (Example 2) serves as an inhibitor of phosphodiesterase PDE7 and exhibits potential analgesic properties.</p>Fórmula:C18H21ClN2O4Forma y color:SolidPeso molecular:364.8214,15-Epoxyeicosatrienoic acid
CAS:<p>14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances</p>Fórmula:C20H32O3Forma y color:SolidPeso molecular:320.47R1498
CAS:<p>R1498 inhibits CDK2, targets angiogenesis and mitosis, and is an oral treatment for liver and stomach cancer.</p>Fórmula:C18H15ClN4OPureza:98%Forma y color:SolidPeso molecular:338.79SH-BC-893
CAS:<p>SH-BC-893: Oral anti-cancer sphingolipid analog, prevents ceramide-related mitochondrial issues, and tackles diet-related obesity.</p>Fórmula:C19H32ClNOForma y color:SolidPeso molecular:325.923,5-Dinitrocatechol
CAS:<p>OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- 3,5-Dinitrocatechol complex.</p>Fórmula:C6H4N2O6Pureza:99.8%Forma y color:SolidPeso molecular:200.11α-Glucosidase-IN-29
CAS:<p>α-Glucosidase-IN-29 (compound 19) is an inhibitor of α-glucosidases, exhibiting an IC50 value of 1.21 μM and a Ki of 1.80 μM.</p>Fórmula:C33H30Br2O7Pureza:98%Forma y color:SolidPeso molecular:698.4FR-186054
CAS:<p>FR-186054, a potent ACAT inhibitor with high oral efficacy, outperforms others in vitro regardless of dosage.</p>Fórmula:C26H27N5OS2Pureza:98%Forma y color:SolidPeso molecular:489.66C24:1 dihydro 1-Deoxyceramide (m18:0/24:1)
CAS:<p>C24:1 dihydro 1-Deoxyceramide (m18:0/24:1) is a lipid molecule that can be used in life science related research. The CAS number of C24:1 dihydro 1-Deoxyceramide (m18:0/24:1) is 1246298-60-1.</p>Fórmula:C42H83NO2Forma y color:SolidPeso molecular:634.11LNP Lipid-8
CAS:<p>LNP Lipid-8 (11-A-M), an ionizable lipid, is utilized in lipid nanoparticles (LNP) for siRNA delivery to T cells without ligand targeting. When loaded with GFP siRNA (siGFP), it significantly silences the GFP gene in a mouse model [1].</p>Fórmula:C42H71NO7Forma y color:SolidPeso molecular:702.021,2-Dilauroyl-sn-glycero-3-phospho-(2R)-glycerol sodium
CAS:<p>1,2-Dilauroyl-sn-glycero-3-phospho-(2R)-glycerol is a type of phosphoglycerol characterized by the presence of lauric acid at the sn-1 and sn-2 positions. [Matreya, LLC. Catalog No. 1443]</p>Fórmula:C30H58O10PNaForma y color:SolidPeso molecular:632.74MT-3014
CAS:<p>MT-3014: Strong, selective brain-penetrating PDE 10A inhibitor; IC50 0.062 nM (human), 0.09 nM (bovine).</p>Fórmula:C23H25F2N7OPureza:98%Forma y color:SolidPeso molecular:453.49LX-1031
CAS:<p>LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.</p>Fórmula:C28H25F3N4O4Pureza:97.123% - 98.97%Forma y color:SolidPeso molecular:538.528(Z)-Eicosenoic Acid
CAS:<p>8(Z)-Eicosenoic acid, a cis-unsaturated free fatty acid featuring a 20-carbon chain, enhances acetylcholine (ACh) receptor channel currents without causing depression and augments PCKε phosphorylation of a substrate peptide in Xenopus oocytes. This acid comprises 6% of the fatty acid composition in seed oil extracted from B. collina.</p>Fórmula:C20H38O2Forma y color:SolidPeso molecular:310.5221-Myristoyl-2-Linoleoyl-3-Oleoyl-rac-glycerol
CAS:<p>1-Myristoyl-2-linoleoyl-3-oleoyl-rac-glycerol, a triacylglycerol, features myristic acid, linoleic acid, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. This compound is prevalent in mature human milk, infant formula fats, and butterfat.</p>Fórmula:C53H96O6Forma y color:SolidPeso molecular:829.33DHODH-IN-22
CAS:<p>DHODH-IN-22: potent, selective DHODH inhibitor, orally active, IC50: 0.3 nM, for AML research.</p>Fórmula:C21H21ClF4N6O5Forma y color:SolidPeso molecular:548.88DNCA
CAS:<p>DNCA, a neutral lipid, facilitates the creation of lipid nanoparticles (LNPs) and is instrumental in [nucleic acid delivery](1).</p>Fórmula:C45H82N4O4Forma y color:SolidPeso molecular:743.16FR-234938
CAS:<p>FR-234938 is a non-nucleoside adenosine deaminase inhibitor with anti-inflammatory activity.</p>Fórmula:C19H21N3O2Pureza:98%Forma y color:SolidPeso molecular:323.39Celgosivir
CAS:<p>Celgosivir (6 O-butanoyl castanospermine) is an inhibitor of α-glucosidase I. In vitro assay, it inhibits bovine viral diarrhoea virus (BVDV) ( IC50: 1.27 μM ).</p>Fórmula:C12H21NO5Pureza:98.03%Forma y color:SolidPeso molecular:259.32-Stearoyl-sn-glycero-3-PC
CAS:<p>2-Stearoyl-sn-glycero-3-phosphatidylcholine (2-Stearoyl-sn-glycero-3-PC) is a lysophospholipid characterized by the presence of stearic acid at the sn-2 position. This compound has been identified in the myocardium of rabbits.</p>Fórmula:C26H54NO7PForma y color:SolidPeso molecular:523.68GW-6604
CAS:<p>GW-6604 is an ALK5 inhibitor and shows clear antifibrotic effects resulting in liver function improvement.</p>Fórmula:C19H14N4Pureza:99.6%Forma y color:SolidPeso molecular:298.34C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0)
CAS:<p>C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) is a lipid molecule that can be used in life science related research. The CAS number of C18 ((±)-2'-hydroxy) Ceramide (d18:1/18:0) is 34249-41-7.</p>Fórmula:C36H71NO4Forma y color:SolidPeso molecular:581.967Kelatorphan
CAS:<p>Kelatorphan is an enkephalin degrading enzyme full inhibitor.</p>Fórmula:C14H18N2O5Pureza:98%Forma y color:SolidPeso molecular:294.3Homonojirimycin
CAS:<p>Homonojirimycin is an alpha-glucosidase inhibitor.</p>Fórmula:C7H15NO5Pureza:98%Forma y color:SolidPeso molecular:193.2
