Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(270 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(97 productos)
- Lípido(59 productos)
- Lipoxigenasa(125 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8626 productos de "Metabolismo"
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Adibendan
CAS:<p>Adibendan (Adibendanum) is a selective inhibitor of PDE3 with an IC50 of 2.0 μM.</p>Fórmula:C16H14N4OPureza:99.52% - >99.99%Forma y color:SolidPeso molecular:278.31SHP394
CAS:<p>SHP394 is an orally efficacious inhibitor of protein tyrosine phosphatase SHP2 (IC50: 23 nM).</p>Fórmula:C20H25F3N6O2SPureza:98%Forma y color:SolidPeso molecular:470.51S-(p-Nitrobenzyl)glutathione
CAS:<p>S-(p-Nitrobenzyl)glutathione acts as a competitive inhibitor of glutathionase.</p>Fórmula:C17H22N4O8SForma y color:SolidPeso molecular:442.441,2-Dimyristoyl-3-palmitoyl-rac-glycerol
CAS:<p>1,2-Dimyristoyl-3-palmitoyl-rac-glycerol (MMP) is a triacylglycerol comprising myristic acid and palmitic acid [1].</p>Fórmula:C47H90O6Forma y color:SolidPeso molecular:751.21Glycosidase-IN-1
CAS:<p>Glycosidase-IN-1, a D-mannose-derived inhibitor, has hypoglycemic effects and aids in creating immunosuppressants and β-glucosidase blockers.</p>Fórmula:C13H23NO5Pureza:98%Forma y color:SolidPeso molecular:273.33Quercetin 7-glucuronide
CAS:<p>Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a Quercetin metabolite found in Madagascarian Uncarina species, has the capability to inhibit LDL</p>Fórmula:C21H18O13Pureza:98%Forma y color:SolidPeso molecular:478.36CoPoP
CAS:<p>CoPoP, a liposome-based vaccine adjuvant, holds potential for application in cancer research [1].</p>Fórmula:C57H80CoN5O9PForma y color:SolidPeso molecular:1069.18LFHP-1c
CAS:<p>LFHP-1c, a neuroprotective PGAM5 inhibitor, demonstrates efficacy in preserving blood-brain barrier integrity following ischemic stroke.</p>Fórmula:C55H64N6O4Pureza:98.07%Forma y color:SolidPeso molecular:873.13HIF-2α-IN-13
CAS:<p>HIF-2α-IN-13 (18) acts as a HIF-2α inhibitor and exhibits an IC 50 value of 2.7 μM.</p>Fórmula:C15H14ClF4NO2Forma y color:SolidPeso molecular:351.72α-Glucosidase-IN-29
CAS:<p>α-Glucosidase-IN-29 (compound 19) is an inhibitor of α-glucosidases, exhibiting an IC50 value of 1.21 μM and a Ki of 1.80 μM.</p>Fórmula:C33H30Br2O7Pureza:98%Forma y color:SolidPeso molecular:698.411-dehydro Thromboxane B3
CAS:<p>11-Dehydro Thromboxane B3 (11-dehydro TXB3) serves as a urinary metabolite of TXA3 in humans following an increased dietary intake of EPA.</p>Fórmula:C20H30O6Forma y color:SolidPeso molecular:366.5RP 70676
CAS:RP 70676 is a potent ACAT inhibitor(rat and rabbit ACAT with IC50 of 25 and 44 nM ).Fórmula:C25H28N4SPureza:99.92%Forma y color:SolidPeso molecular:416.584′-DTMP
CAS:<p>4′-DTMP (4-Demethyltrimethoprim) is a DHFR inhibitor with antimicrobial activity against Escherichia coli.</p>Fórmula:C13H16N4O3Pureza:98%Forma y color:SolidPeso molecular:276.2911-Dehydro-2,3-Dinor Thromboxane B2
CAS:<p>11-Dehydro-2,3-Dinor Thromboxane B2 is a metabolite of Thromboxane B2 (TXB2), formed by the oxidation of TXB2 via 11-Hydroxy Thromboxane Dehydrogenase.</p>Fórmula:C18H28O6Forma y color:SolidPeso molecular:340.41AZD-1656
CAS:<p>AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2</p>Fórmula:C24H26N6O5Pureza:97.07% - 99.37%Forma y color:SolidPeso molecular:478.5Ac-VDVAD-CHO
CAS:<p>Ac-VDVAD-CHO is an inhibitor of caspase-2 and caspase-3 (IC50: 46 nM for caspase-2 and 15 nM for caspase-3) [1].</p>Fórmula:C23H37N5O10Pureza:98%Forma y color:SolidPeso molecular:543.57Z-Pro-Pro-CHO
CAS:<p>Z-Pro-Pro-CHO acts as a prolyl oligopeptidase inhibitor with half-maximal inhibitory concentrations (IC50) of 0.16 μM for human prolyl oligopeptidase and 0.01</p>Fórmula:C18H22N2O4Pureza:98%Forma y color:SolidPeso molecular:330.38BIO-32546
CAS:<p>BIO-32546 (S-isomer) is a highly potent regulator of autotaxin (ATX) with an IC50 value of 1 nM.</p>Fórmula:C28H31F6NO3Pureza:98.03%Forma y color:SolidPeso molecular:543.54IDH1 Inhibitor 2
CAS:<p>IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).</p>Fórmula:C26H22N4OPureza:98%Forma y color:SolidPeso molecular:406.4812,15-epoxy-13-methyl-12,14-Eicosadienoic Acid
CAS:<p>12,15-Epoxy-13-methyl-12,14-eicosadienoic acid, a furan fatty acid first identified in northern pike (E. lucius), exhibits elevated levels in the liver of starving cod.</p>Fórmula:C21H36O3Forma y color:SolidPeso molecular:336.51Edaglitazone
CAS:<p>Edaglitazone (R-483) is a PPARγ agonist with antiplatelet activity that can be used in studies of diabetes and obesity.</p>Fórmula:C24H20N2O4S2Pureza:98%Forma y color:SolidPeso molecular:464.56ICMT-IN-2
CAS:<p>ICMT-IN-2 (compound 45) serves as an ICMT inhibitor with an IC50 value of 0.168 μM [1].</p>Fórmula:C21H26FNOForma y color:SolidPeso molecular:327.44ICMT-IN-24
CAS:<p>ICMT-IN-24 (compound 63) is an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), exhibiting potent activity with an IC50 value of 0.19 μM [1].</p>Fórmula:C22H28ClNO2Forma y color:SolidPeso molecular:373.921-Myristoyl-2-Palmitoyl-3-Butyryl-rac-glycerol
CAS:<p>1-Myristoyl-2-palmitoyl-3-butyryl-rac-glycerol, a triacylglycerol with myristic acid (at the sn-1 position), palmitic acid (at the sn-2 position), and butyric acid (at the sn-3 position), has been detected in human breast milk.</p>Fórmula:C37H70O6Forma y color:SolidPeso molecular:6111,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine
CAS:<p>1,2-Diheptadecanoyl-sn-glycero-3-phosphorylcholine (DHPC) is a derivative of phosphatidylcholine (PC) that exhibits biological activity, functioning as a</p>Fórmula:C42H84NO8PForma y color:SolidPeso molecular:762.09ICMT-IN-40
CAS:<p>ICMT-IN-40 (compound 19) is a potent inhibitor of ICMT, exhibiting an IC50 value of 0.031 μM [1].</p>Fórmula:C22H29NOForma y color:SolidPeso molecular:323.47Leramistat
CAS:<p>Leramistat is a mitochondrial complex I (NIC1) inhibitor that alters cellular metabolism and reduces proliferation in human primary lung fibroblasts.</p>Fórmula:C20H21ClN2O3SPureza:98.51%Forma y color:SolidPeso molecular:404.91EMD638683 R-Form
CAS:<p>EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. EMD638683 R-Form is the R-form of EMD638683.</p>Fórmula:C18H18F2N2O4Forma y color:SolidPeso molecular:364.34SCD1/5-IN-1
CAS:<p>SCD1/5-IN-1 (Compound 10), a selective SCD1/5 inhibitor, is utilized in the research of neurological diseases [1].</p>Fórmula:C12H10N4O3Forma y color:SolidPeso molecular:258.237Oxalomalic acid trisodium
CAS:<p>Oxalomalic acid (Oxalomalate) trisodium, an inhibitor of aconitase and NADP-dependent isocitrate dehydrogenase, suppresses nitrite production and inducible nitric oxide synthase (iNOS) protein expression in lipopolysaccharide-activated J774 macrophages [1].</p>Fórmula:C6H3Na3O8Forma y color:SolidPeso molecular:272.05Taurohyocholic Acid sodium
CAS:<p>Taurohyocholic acid (THCA), a taurine-conjugated form of porcine-specific primary bile acid hyocholic acid, inhibits cholesterol crystal precipitation by stabilizing cholesterol in the liquid-crystalline phase and prevents cholestasis and cellular necrosis in isolated rat livers induced by taurolithocholic acid. Additionally, THCA levels rise in the urine of patients with hepatitis B-induced cirrhosis.</p>Fórmula:C26H44NO7SNaForma y color:SolidPeso molecular:537.69XL041
CAS:<p>XL041 (BMS-852927) is an agonist of LXRβ-selective.</p>Fórmula:C29H28Cl2F2N2O4SPureza:98%Forma y color:SolidPeso molecular:609.51FTI-2153
CAS:<p>FTI-2153 inhibits farnesyltransferase with 1.4 nM IC50, >3000x more effective on H-Ras than Rap1A.</p>Fórmula:C25H30N4O3SForma y color:SolidPeso molecular:466.6(R)-IDO/TDO-IN-1
CAS:<p>(R)-IDO/TDO-IN-1 (compound 25), an indoleamine-2,3-dioxygenase (IDO) inhibitor, demonstrates good pharmacokinetic properties and exerts anti-tumor effects in the MC38 xenograft model. This compound exhibits synergy when combined with the anti-PD-1 monoclonal antibody (SHR-1210) [1].</p>Fórmula:C25H24FN5Forma y color:SolidPeso molecular:413.49Biliverdin
CAS:<p>Biliverdin, produced through the oxidation of bilirubin, can also be synthesized through a non-protoporphyrin pathway in Corynebacterium glutamicum [1].</p>Fórmula:C33H34N4O6Forma y color:SolidPeso molecular:582.65ICMT-IN-21
CAS:<p>ICMT-IN-21 (compound 6ag) is an ICMT inhibitor with an IC50 value of 8.8 µM, featuring sulfonamide-modified farnesyl cysteine (SMFC).</p>Fórmula:C22H33NO4S3Forma y color:SolidPeso molecular:471.7AalphaC
CAS:<p>AalphaC (2-Amino-alpha-carboline) is a potential carcinogen.</p>Fórmula:C11H9N3Pureza:99.32%Forma y color:Crystalline SolidPeso molecular:183.21(R)-Azasetron besylate
CAS:<p>(R)-Azasetron besylate (SENS-401), an orally active calcineurin inhibitor, has been shown to mitigate cisplatin-induced hearing loss and cochlear damage [1][2].</p>Fórmula:C23H26ClN3O6SPureza:98%Forma y color:SolidPeso molecular:507.99RORγt inverse agonist 26
CAS:<p>RORγt inverse agonist 26, a potent reverse agonist of RORγt, effectively modulates Th17 cell differentiation and suppresses IL-17 production.</p>Fórmula:C27H21F7N2O5SForma y color:SolidPeso molecular:618.52C2 Dihydro Ceramide (d18:0/2:0)
CAS:<p>C2 Dihydro Ceramide (d18:0/2:0) (C2 Dihydroceramide) is a ceramide that is a precursor of ceramide synthesis and stimulates ABCA1-mediated cholesterol efflux.</p>Fórmula:C20H41NO3Pureza:98%Forma y color:SolidPeso molecular:343.54(S,R)-WT IDH1 Inhibitor 2
CAS:<p>(S,R)-WT IDH1 Inhibitor 2: selectively targets mutant IDH1; IC50 - R132G: 2.9 nM, R132C: 3.8 nM, R132H: 4.6 nM, WT: 46 nM; potential for AML treatment.</p>Fórmula:C28H28FN5O3Forma y color:SolidPeso molecular:501.55RORγt inverse agonist 14
CAS:<p>RORγt inverse agonist 14 (8e) is a potent, selective, and orally active compound with an EC50 of 2.5 nM, exhibiting anti-inflammatory activity.</p>Fórmula:C26H26F8N2O6S2Pureza:98%Forma y color:SolidPeso molecular:678.61L-690488
CAS:<p>L-690488 has more effective cell penetration than L-690330. L-690488 is a prodrug of L-690330 and is a selective inositol monophosphatase (IMPase) inhibitor.</p>Fórmula:C32H52O16P2Pureza:98%Forma y color:SolidPeso molecular:754.69GSK2256294A
CAS:<p>GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively.</p>Fórmula:C21H24F3N7OPureza:99.86% - 99.86%Forma y color:SolidPeso molecular:447.46DPM-1001 trihydrochloride
<p>DPM-1001 trihydrochloride: Potent PTP1B inhibitor, IC50 100 nM, oral, non-competitive, anti-diabetic.</p>Fórmula:C35H60Cl3N3O3Forma y color:SolidPeso molecular:677.23OSMI-2
CAS:<p>OSMI-2 is a cell-permeable inhibitor of O-linked N-acetylglucosamine transferase (OGT).</p>Fórmula:C26H25N3O7S2Pureza:98%Forma y color:SolidPeso molecular:555.62ICMT-IN-9
CAS:<p>ICMT-IN-9 (compound 47) is a potent ICMT inhibitor with an IC50 value of 0.16 μM [1].</p>Fórmula:C22H28FNO2Forma y color:SolidPeso molecular:357.46GPi 688
CAS:<p>glycogen phosphorylase inhibitor</p>Fórmula:C19H18ClN3O4SPureza:98%Forma y color:SolidPeso molecular:419.88Bemfivastatin hemicalcium
CAS:<p>Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent.</p>Fórmula:C34H36FN2O6CaForma y color:SolidPeso molecular:607.67SMS1-IN-1
CAS:<p>SMS1-IN-1 is a potent inhibitor of sphingomyelin synthase 1 (SMS1, IC50 = 2.1 μM), and can be used in the atherosclerosis studies.</p>Fórmula:C23H23BrN2O4SPureza:99.81%Forma y color:SolidPeso molecular:503.41
