Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(270 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(97 productos)
- Lípido(59 productos)
- Lipoxigenasa(125 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8625 productos de "Metabolismo"
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IDH889
CAS:<p>IDH889: Brain-penetrant, mutant-specific IDH1 inhibitor; selective for IDH1 R132* mutations. IC50: 0.02μM (R132H), 0.072μM (R132C), 1.38μM (wild-type).</p>Fórmula:C23H25FN6O2Pureza:≥98%Forma y color:SolidPeso molecular:436.48PPARδ agonist 9
CAS:<p>PPARδ agonist 9 (compound 21), with an EC50 of 3.6 nM, is effective in vivo, decreasing serum MCP-1 concentrations in mice and markedly reducing atherosclerotic</p>Fórmula:C26H28ClF3N4O3SPureza:98%Forma y color:SolidPeso molecular:569.04Adibendan
CAS:<p>Adibendan (Adibendanum) is a selective inhibitor of PDE3 with an IC50 of 2.0 μM.</p>Fórmula:C16H14N4OPureza:99.52% - >99.99%Forma y color:SolidPeso molecular:278.31MLS000545091
CAS:<p>MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.</p>Fórmula:C14H15ClN2OPureza:99.84%Forma y color:SolidPeso molecular:262.73PPAR agonist 1
CAS:<p>PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.</p>Fórmula:C20H25NO6SPureza:98%Forma y color:SolidPeso molecular:407.48ICMT-IN-43
CAS:<p>ICMT-IN-43 (compound 22) acts as a potent inhibitor of the enzyme ICMT, exhibiting an inhibitory concentration (IC50) value of 0.04 μM [1].</p>Fórmula:C23H31NOForma y color:SolidPeso molecular:337.5DSTAP chloride
CAS:<p>DSTAP chloride (CDESA), a cationic lipid, is utilized in the formation of lipid nanoparticles (LNPs) and exhibits high transfection efficiency [1].</p>Fórmula:C42H84ClNO4Forma y color:SolidPeso molecular:702.57CL4H6
CAS:<p>CL4H6, a pH-sensitive cationic lipid, serves as the primary constituent of lipid nanoparticles (LNPs). These LNPs are instrumental in targeting and delivering siRNA, leading to a potent gene-silencing response [1] [2].</p>Fórmula:C59H113NO5Forma y color:SolidPeso molecular:916.53CYP3A4-IN-2
CAS:<p>CYP3A4-IN-2, a potent CYP3A4 inhibitor (IC50: 0.055 μM), is a hydrophobic ritonavir analog with immunosuppressive and antiviral properties.</p>Fórmula:C33H38N4O3SForma y color:SolidPeso molecular:570.74Quizalofop-P
CAS:<p>Quizalofop-P, a selective herbicide, is absorbed by weed stems and leaves before translocating both upward and downward within the plant, concentrating in</p>Fórmula:C17H13ClN2O4Pureza:98%Forma y color:SolidPeso molecular:344.75CAY10435
CAS:<p>CAY10435, a β-ketooxazapyridine and selective FAAH inhibitor, exhibits antimicrobial properties. It binds non-competitively to the FAAH of Dictyostelium discoideum, demonstrating a Kd value of 0.57 nM [1] [2].</p>Fórmula:C18H26N2O2Forma y color:SolidPeso molecular:302.41Sch59498
CAS:<p>Sch59498 is a potent phosphodiesterase 1c (Pde1c) inhibitor.</p>Fórmula:C17H25N5OPureza:98%Forma y color:SolidPeso molecular:315.41PHD-IN-2
CAS:<p>PHD-IN-2 (Compound 91), a potent PHD antagonist with an IC50 of less than 5 nM, effectively stimulates erythropoietin synthesis in HEP3B cells with an EC50 of</p>Fórmula:C26H27N7O4Pureza:98%Forma y color:SolidPeso molecular:501.54CYP17-IN-1
CAS:<p>CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.</p>Fórmula:C18H17FN2SPureza:99.14% - 99.83%Forma y color:SolidPeso molecular:312.4CI-1044
CAS:<p>CI-1044 is an inhibitor of PDE4 (IC50s: 0.29, 0.08, 0.56, 0.09 μM for PDE4A5, PDE4B2, PDE4C2 and PDE4D3).</p>Fórmula:C23H19N5O2Forma y color:SolidPeso molecular:397.43Difamilast
CAS:<p>Difamilast is a selective inhibitor of phosphodiesterase-4 (PDE4) with particularly efficient inhibition of subtype B (IC50=11.2 nM).</p>Fórmula:C23H24F2N2O5Pureza:99.64%Forma y color:SolidPeso molecular:446.44IDH1 Inhibitor 5
CAS:<p>IDH1 Inhibitor 5 targets MOG cells (IC50: 64.4 nM) and R132H mutant IDH1 gliomas (IC50: 34.9 nM).</p>Fórmula:C26H34N4O3Forma y color:SolidPeso molecular:450.57Dioleyldimethylammonium chloride
CAS:<p>Dioleyldimethylammonium chloride (DODAC) is a cationic lipid utilized as a transfection reagent [1].</p>Fórmula:C38H76ClNForma y color:SolidPeso molecular:582.47Kelatorphan
CAS:<p>Kelatorphan is an enkephalin degrading enzyme full inhibitor.</p>Fórmula:C14H18N2O5Pureza:98%Forma y color:SolidPeso molecular:294.39(Z),11(E)-Conjugated Linoleic Acid methyl ester
CAS:<p>9(Z),11(E)-Conjugated Linoleic Acid Methyl Ester, identified in lemon grass (C. flexuosus), serves as a standard for quantifying conjugated linoleic acids in thermally stressed olive oil and trans fats in bakery products. [Matreya, LLC. Catalog No. 1255]</p>Fórmula:C19H34O2Forma y color:SolidPeso molecular:294.4792-Myristyldipalmitin
CAS:<p>2-Myristyl dipalmitin (PMP), a triglyceride of palmitic acid, shows potential as a lipid marker for Wilson's disease (WD) [1] [2].</p>Fórmula:C49H94O6Forma y color:SolidPeso molecular:779.27FM26
CAS:FM26, an isoxazole-based RORγt inverse agonist, cuts EL4 IL-17a mRNA; potent with 264 nM IC50.Fórmula:C22H15ClF3N3O3Pureza:98%Forma y color:SolidPeso molecular:461.82LNP Lipid-8
CAS:<p>LNP Lipid-8 (11-A-M), an ionizable lipid, is utilized in lipid nanoparticles (LNP) for siRNA delivery to T cells without ligand targeting. When loaded with GFP siRNA (siGFP), it significantly silences the GFP gene in a mouse model [1].</p>Fórmula:C42H71NO7Forma y color:SolidPeso molecular:702.02FXa-IN-1
CAS:<p>FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.</p>Fórmula:C24H18F5N5OForma y color:SolidPeso molecular:487.42(Rac)-Lonafarnib
CAS:<p>(Rac)-Lonafarnib is a racemic FTase inhibitor, effective against H-ras, K-ras, N-ras (IC50: 1.9, 5.2, 2.8 nM), and has anti-HDV properties.</p>Fórmula:C27H31Br2ClN4O2Forma y color:SolidPeso molecular:638.82Gisadenafil
CAS:<p>Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.</p>Fórmula:C23H33N7O5SPureza:98.82% - 99.50%Forma y color:SolidPeso molecular:519.62Iomazenil
CAS:<p>Iomazenil is an antagonist and partial inverse agonist of benzodiazepine and potential therapy for alcohol abuse.</p>Fórmula:C15H14IN3O3Pureza:98%Forma y color:SolidPeso molecular:411.19sPLA2 inhibitor 1
CAS:<p>KH064 is a sPLA2-IIA inhibitor of oral activity.</p>Fórmula:C31H37NO4Forma y color:SolidPeso molecular:487.63Rilapladib
CAS:<p>Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activating</p>Fórmula:C40H38F5N3O3SPureza:99.92%Forma y color:SolidPeso molecular:735.8RS 8359
CAS:<p>RS 8359 is a selective MAO-A reversible inhibitor with a 2200:1 A:B ratio, exhibiting antidepressant effects.</p>Fórmula:C14H12N4OPureza:99.3%Forma y color:SolidPeso molecular:252.27Cudetaxestat
CAS:<p>Cudetaxestat (BLD-0409) is a potent inhibitor of orally active autotaxin.</p>Fórmula:C21H15Cl2F2N3O2SPureza:99.9%Forma y color:SolidPeso molecular:482.33TPN171
CAS:<p>TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6, which has the potential for the treatment of pulmonary</p>Fórmula:C24H35N5O3Pureza:>99.99%Forma y color:SolidPeso molecular:441.57PDE9-IN-(S)-C33
CAS:<p>PDE9-IN-(S)-C33: potent PDE9 inhibitor with 11 nM IC50, for CNS diseases and diabetes study.</p>Fórmula:C18H20ClN5OPureza:98.75%Forma y color:SolidPeso molecular:357.84WAY-297848
CAS:<p>WAY-297848 is a novel glucokinase activator for the prevention or treatment of hyperglycemia, diabetes mellitus, obesity, dyslipidemia, and metabolic syndrome.</p>Fórmula:C13H13ClN2O2SPureza:98.19%Forma y color:SolidPeso molecular:296.77DGAT-1 inhibitor 2
CAS:<p>DGAT-1 inhibitor 2: effective against obesity, targets enzyme in triglyceride synthesis for diabetes treatment.</p>Fórmula:C24H28N4O3Pureza:98.36%Forma y color:SolidPeso molecular:420.5KB-74935
CAS:<p>KB-74935: enzyme inhibitor, mineralocorticoid blocker, treats cholesterol, hypolipidemia, neurological issues, Alzheimer's.</p>Fórmula:C19H18ClF4N3O3SPureza:99.4%Forma y color:SolidPeso molecular:479.887-BIA
CAS:<p>7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties and can be used in the study of neuropathic pain.</p>Fórmula:C15H18O6Pureza:≥98% - ≥98%Forma y color:SolidPeso molecular:294.3TP-10
CAS:<p>TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.</p>Fórmula:C26H19F3N4OPureza:99.21%Forma y color:SolidPeso molecular:460.45NEP-IN-1
CAS:<p>NEP-IN-1 is an inhibitor of neutral endopeptidase (NEP, IC50 = 2 nM) and can be used in studies about female sexual arousal disorders.</p>Fórmula:C21H30ClNO4Pureza:99.69%Forma y color:SolidPeso molecular:395.92CCT365623
CAS:<p>CCT365623: oral Lysyl Oxidase inhibitor, potent, selective, good pharmacokinetics, anti-metastatic.</p>Fórmula:C18H17NO4S3Pureza:97.299% - 99.49%Forma y color:SolidPeso molecular:407.53ALDH2 modulator 1
CAS:<p>ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.</p>Fórmula:C18H18ClFN2O3Pureza:99.68%Forma y color:SoildPeso molecular:364.8ML400
CAS:<p>ML400 (CID73050863) is an allosteric inhibitor of LMPTP with an EC50 of 1μM. ML400 displays good cell-based activity and rodent pharmacokinetics.</p>Fórmula:C24H29N3OPureza:99.95%Forma y color:SolidPeso molecular:375.51Cis-22a
CAS:<p>Cis-22a: selective TRPV6 inhibitor (IC50=0.32μM), halts T47D breast cancer cell growth.</p>Fórmula:C24H30F3N3O2Pureza:99.07%Forma y color:SolidPeso molecular:449.51CB29
CAS:<p>CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).</p>Fórmula:C15H15N3O5SPureza:99.36%Forma y color:SolidPeso molecular:349.36NPAS3-IN-1
CAS:<p>NPAS3-IN-1 is an NPAS3-ARNT heterodimerization inhibitor that regulates NPAS3 transcription by modulating the heterodimerization of NPAS3 with ARNT.</p>Fórmula:C10H5N3O2S3Pureza:99.56%Forma y color:SolidPeso molecular:295.36Ranirestat
CAS:<p>Ranirestat (AS-3201) is an AR inhibitor with neuroprotective properties that improves peripheral nerve dysfunction in rats with advanced diabetic polyneuropathy</p>Fórmula:C17H11BrFN3O4Pureza:98.83% - 99.44%Forma y color:SolidPeso molecular:420.19OGT 2115
CAS:<p>OGT 2115 blocks heparanase (IC50=0.4µM), cleaving heparan sulfate; antiangiogenic (IC50=1µM).</p>Fórmula:C24H16BrFN2O4Pureza:97.17%Forma y color:SolidPeso molecular:495.3AMG 579
CAS:<p>AMG 579 is an efficacious and selective inhibitor of PDE10A (IC50 = 0.1 nM).</p>Fórmula:C25H23N5O3Pureza:99.87%Forma y color:SolidPeso molecular:441.48Calcium channel-modulator-1
CAS:<p>Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.</p>Fórmula:C26H24Cl2N2O7SPureza:99.95%Forma y color:SolidPeso molecular:579.45Ecopladib
CAS:<p>Ecopladib inhibits cPLA2α with IC50 of 0.15 μM (micelles) & 0.11 μM (rat blood).</p>Fórmula:C39H33Cl3N2O5SPureza:95.15%Forma y color:SolidPeso molecular:748.11
