Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(177 productos)
- Caseína quinasa(130 productos)
- DHFR(32 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(267 productos)
- FAAH(63 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(32 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(53 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(32 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(96 productos)
- Lípido(59 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(165 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8597 productos de "Metabolismo"
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JTT-553
CAS:<p>JTT-553 is a DGAT1 inhibitor with an IC50 of 2.38 nM. It effectively reduces plasma levels of glucose, insulin, non-esterified fatty acids (NEFA), total cholesterol (TC), and liver triglycerides (TG). JTT-553 enhances insulin-dependent glucose absorption and glucose intolerance in the adipose tissue of diet-induced obese (DIO) mice. In KK-Ay mice, it lowers TNF-α mRNA levels and elevates GLUT4 mRNA levels in adipose tissue. By contributing to weight loss, JTT-553 improves insulin resistance in adipose tissue and overall glucose metabolism. This compound is useful for research on obesity and type 2 diabetes mellitus (T2DM).</p>Fórmula:C25H27F3N4O3Forma y color:SolidPeso molecular:488.507-Hydroxy-4-phenylcoumarin
CAS:<p>7-Hydroxy-4-phenylcoumarin is a dual inhibitor of ALDH-2 and MAO, with IC50 values of 1.5 µM and 0.5 µM, respectively.</p>Fórmula:C15H10O3Forma y color:SolidPeso molecular:238.238LEQ803
CAS:<p>LEQ803 (N-DesmethylRibociclib) is a metabolite of the CDK4/6 inhibitor Ribociclib, produced through metabolism by CYP3A4. This compound holds potential applications in the field of oncology.</p>Fórmula:C22H28N8OForma y color:SolidPeso molecular:420.511Casein kinase 1δ-IN-19
CAS:<p>Casein kinase1δ-IN-19 (compound 492) is a potent inhibitor of casein kinase 1δ. It is utilized in research related to neurodegenerative disorders, such as Alzheimer's disease.</p>Fórmula:C21H19N5O3Forma y color:SolidPeso molecular:389.407Squalestatin 3
CAS:<p>Squalestatin 3 is an inhibitor of squalene synthase.</p>Fórmula:C25H30O13Pureza:98%Forma y color:SolidPeso molecular:538.5Magnesium ionophore III
CAS:<p>Magnesium ionophore III (ETH 4030) is an ion carrier that regulates intracellular magnesium ion concentrations. It enhances cellular functions and metabolic activities by increasing the permeability of cell membranes to magnesium ions. Additionally, Magnesium ionophore III is utilized in research to explore the significance of magnesium ions in biological processes and their impact on cellular physiology.</p>Fórmula:C30H58N4O4Forma y color:SolidPeso molecular:538.81LRAT-IN-1
CAS:<p>LRAT-IN-1 (compound 1) is an inhibitor of lecithin retinol acyltransferase (LRAT) with an IC50 value of 21.1 μM. This compound works by inhibiting the esterification of retinol to form retinyl esters, thereby increasing the availability of retinol in the skin to deliver anti-aging benefits. LRAT-IN-1 is under investigation for its potential use as an anti-aging ingredient in cosmetics.</p>Fórmula:C27H47N5O5S2Forma y color:SolidPeso molecular:585.82MAGL-IN-19
CAS:<p>MAGL-IN-19 (compound 7o) is a highly effective and selective inhibitor of MAGL.</p>Fórmula:C21H26F3N3O3Forma y color:SolidPeso molecular:425.454-(4-Bromophenyl)-4-hydroxypiperidine
CAS:<p>4-(4-Bromophenyl)-4-hydroxypiperidine (BPHP) is a metabolite of Bromperidol (BRO), produced through the N-dealkylation of BRO.</p>Fórmula:C11H14BrNOForma y color:SolidPeso molecular:256.139Casein kinase 1δ-IN-26
CAS:<p>Casein kinase1δ-IN-26 (compound 505) is a potent inhibitor of casein kinase 1δ. This compound is applicable in research related to neurodegenerative disorders such as Alzheimer’s disease.</p>Fórmula:C16H13N3O4SForma y color:SolidPeso molecular:343.357(2S,4S)-Sacubitril
CAS:<p>(2S,4S)-Sacubitril (Sacubitril Impurity C) is a stereoisomer derived from Sacubitril which is a potent NEP inhibitor.</p>Fórmula:C24H29NO5Pureza:98%Forma y color:SolidPeso molecular:411.49ZK168281
CAS:<p>ZK168281 is a 1α,25(OH)2D3 analog, VDR antagonist with 0.1 nM Kd, and blocks receptor CoA interaction.</p>Fórmula:C32H46O5Pureza:98%Forma y color:SolidPeso molecular:510.70BMS-185354
CAS:<p>BMS-185354 is a selective RARγ activator with an EC50 value of 28 nM, offering potential for cancer research.</p>Fórmula:C26H27NO3Forma y color:SolidPeso molecular:401.497Enpp-1-IN-12
<p>ENPP1-IN-12 is a potent, oral ENPP1 inhibitor with a Ki of 41 nM and anti-tumor properties.</p>Fórmula:C17H19N5O3SForma y color:SolidPeso molecular:373.43SMase-IN-1
CAS:<p>SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase (SMase) inhibitor with an IC50 value of 6.43 µM against Bacillus cereus SMase. It also inhibits eqBuChE with an inhibition rate of 59.50% at a concentration of 50 µM. SMase-IN-1 forms a complex with Cu2+ through bio-metal interactions and can inhibit hemolysis of sheep red blood cells induced by Bacillus cereus.</p>Fórmula:C8H5ClN2OSForma y color:SolidPeso molecular:212.656GW461484A
CAS:<p>GW461484A is a small molecule inhibitor targeting Candida albicans Yck2, exhibiting an IC50 of 0.11 µM. It has a MIC80 of 12.5 µM against C. albicans. GW461484A shows potential for research into fungal diseases, including drug-resistant Candida infections.</p>Fórmula:C19H14FN3Forma y color:SolidPeso molecular:303.333HIF-2α-IN-5
CAS:<p>HIF-2α-IN-5 is a potent HIF-2α inhibitor with an IC 50 of < 50 nM [1].</p>Fórmula:C15H12F4O3S2Forma y color:SolidPeso molecular:380.382,4-Dihydroxybutanoic acid
CAS:<p>2,4-Dihydroxybutanoic acid is typically not found in extracts of normal human urine and is present only in trace amounts in newborns, while cases of succinic semialdehyde dehydrogenase deficiency consistently exhibit elevated levels of this metabolite.</p>Fórmula:C4H8O4Forma y color:SolidPeso molecular:120.10JTZ-951 HCl
CAS:<p>JTZ-951 is a potent and orally active inhibitor of hypoxia inducible factor prolyl hydroxylase (PHD).</p>Fórmula:C17H17ClN4O4Pureza:98%Forma y color:SolidPeso molecular:376.799-cis-β-Carotene
CAS:<p>9-cis-β-Carotene, a precursor of retinal, is cleaved by beta-carotene oxygenase 1 (BCMO1) to produce 9-cis-retinal.</p>Fórmula:C40H56Pureza:98%Forma y color:SolidPeso molecular:536.87GK420
CAS:<p>GK420 (AVX420) is a potent inhibitor of cytoplasmic phospholipase A2α (cPLA2α), with an XI(50) value of 0.0016. It effectively inhibits the release of arachidonic acid, with an EC50 of 0.09 μM. GK420 plays a significant role in cancer research.</p>Fórmula:C20H25NO5SForma y color:SolidPeso molecular:391.481(3S,17S)-FD-895
CAS:<p>(3S,17S)-FD-895 is an analogue of FD-895. It inhibits the growth of HCT116 cells and shows splicing-modulating activity. This compound can be utilized in cancer research.</p>Fórmula:C31H50O9Forma y color:SolidPeso molecular:566.723(S)-CPP sodium
CAS:<p>(S)-CPP sodium serves as an inhibitor of the branched-chain α-keto acid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, (S)-CPP (IC50 of 6.3 μM) inhibits BDK, which activates the complex, leading to a significant reduction in the levels of leucine/isoleucine and valine in the plasma of wild-type mice.</p>Fórmula:C9H8ClNaO2Forma y color:SolidPeso molecular:206.60CK1δ-IN-8
CAS:<p>CK1δ-IN-8 (Compound 429) is a CK1δ inhibitor suitable for Alzheimer's disease research.</p>Fórmula:C14H9N3O2S2Forma y color:SolidPeso molecular:315.37Casein kinase 1δ-IN-30
CAS:<p>Casein kinase1δ-IN-30 (Compound 581) is an inhibitor of casein kinase 1δ (CK1δ). It can be utilized in research related to neurodegenerative diseases.</p>Fórmula:C18H15BrN6O2SForma y color:SolidPeso molecular:459.32Implitapide
CAS:<p>Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).</p>Fórmula:C35H37N3O2Pureza:98%Forma y color:SolidPeso molecular:531.69Etoricoxib N1'-oxide
CAS:<p>EtoricoxibN1'-oxide is a metabolite of Etoricoxib. It does not inhibit COX-1 and does not significantly inhibit COX-2.</p>Fórmula:C18H15ClN2O3SForma y color:SolidPeso molecular:374.841BT-114143
CAS:<p>BT-114143 is a plasminogen activator inhibitor with an IC50 of 8.42 μM. It is applicable in research related to hemorrhagic diseases caused by excessive fibrinolysis, including traumatic bleeding, severe menorrhagia, postpartum hemorrhage, and complications of hemophilia.</p>Fórmula:C8H11N2O3PForma y color:SolidPeso molecular:214.158ZK159222
CAS:<p>ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.</p>Fórmula:C32H48O5Pureza:98%Forma y color:SolidPeso molecular:512.72MRS4458
CAS:<p>MRS4458 is an effective inhibitor of the P2Y14 Receptor.</p>Fórmula:C24H20F3N5O3SPureza:98%Forma y color:SolidPeso molecular:515.51LDHA-IN-5
CAS:<p>LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primary</p>Fórmula:C27H22FN7O6S3Forma y color:SolidPeso molecular:655.7FXR agonist 12
CAS:<p>FXR agonist12 (Compound C7) is an orally active FXR agonist. It downregulates bile acid synthesis-related genes and upregulates bile acid transport-related genes in HepG2 cells. FXR agonist12 alleviates ANIT-induced cholestasis and reduces liver damage and fibrosis in a mouse model of NASH.</p>Fórmula:C26H44O3Forma y color:SolidPeso molecular:404.626PTP1B-IN-18
<p>PTP1B-IN-18 is an orally active, fully mixed protein tyrosine phosphatase 1B (PTP1B) inhibitor (Ki: 35.2 μM).PTP1B-IN-18 can be used to study type 2 diabetes.</p>Fórmula:C26H19N3O4SForma y color:SolidPeso molecular:469.51Carbonic anhydrase inhibitor 10
<p>CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.</p>Fórmula:C14H17N5O3SForma y color:SolidPeso molecular:335.38sEH inhibitor-2
<p>SEH inhibitor-2 is an orally active sEH blocker (IC50=0.9 nM) with predicted 71.2-88.4% absorption, potentially aiding cardiovascular health.</p>Fórmula:C23H18N4O3Forma y color:SolidPeso molecular:398.41DRB18
CAS:<p>DRB18 inhibits GLUT proteins, altering glucose metabolism and inducing cancer cell death by G1/S arrest and oxidative stress.</p>Fórmula:C22H23ClN2O2Pureza:99.54%Forma y color:SolidPeso molecular:382.88BE1218
CAS:<p>BE1218 is a liver X receptor (LXR) inverse agonist active on LXRα and LXRβ with an IC50 of 9 nM and 7 nM, respectively.</p>Fórmula:C30H30FNO4S2Pureza:99.7%Forma y color:SoildPeso molecular:551.69Glycosyltransferase-IN-1
<p>Glycosyltransferase-IN-1 is a glycosyltransferase inhibitor with bacteriostatic activity, inhibiting MSSA, MRSA, Bacillus subtilis, and Enterobacteriaceae.</p>Fórmula:C19H21N5OPureza:99.76%Forma y color:SolidPeso molecular:335.4STK-15
CAS:<p>STK-15 is a candidate for use as a fatty acid binding protein 5 (FABP5) inhibitor.</p>Fórmula:C34H29NO5Pureza:98.05%Forma y color:SolidPeso molecular:531.6FABPs ligand 6
CAS:<p>FABPs ligand 6 (MF6) is an inhibitor of FABP5 and FABP7.</p>Fórmula:C28H27FN2O3Pureza:97.45%Forma y color:SolidPeso molecular:458.52JX237
CAS:<p>JX237 is an SLC6A19 inhibitor, a transporter protein that neutralizes amino acid uptake by the liver, and can be used in the study of cardiovascular disease.</p>Fórmula:C11H15BrN2OPureza:99.19%Forma y color:SolidPeso molecular:271.15ALOX15-IN-2
CAS:<p>ALOX15-IN-2: Potent ALOX15 inhibitor. IC50: 1.55 μM for LA; 2.79 μM for AA. Stops linoleic/arachidonic acid oxidation.</p>Fórmula:C23H29N3O4SPureza:98.10%Forma y color:SolidPeso molecular:443.56WAY-213613 hydrochloride
CAS:<p>WAY-213613 hydrochloride: potent, selective GLT-1/EAAT2 inhibitor (IC50 85 nM); weaker for EAAT1/3; inactive at glutamate receptors; research tool for CNS.</p>Fórmula:C16H13BrF2N2O4Pureza:99.14% - 99.37%Forma y color:SoildPeso molecular:415.19Etamicastat hydrochloride
CAS:<p>Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.</p>Fórmula:C14H16ClF2N3OSPureza:98.54%Forma y color:SolidPeso molecular:347.81BMS453
CAS:<p>BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin.</p>Fórmula:C27H24O2Pureza:99.93%Forma y color:SolidPeso molecular:380.48Aleglitazar
CAS:<p>Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.</p>Fórmula:C24H23NO5SPureza:99.03%Forma y color:SolidPeso molecular:437.51CP-642931
CAS:<p>CP-642931 (Sorbitol dehydrogenase-IN-1) is a sorbitol dehydrogenase inhibitor used in the study of diabetes mellitus and cardiovascular disease.</p>Fórmula:C17H25N7OPureza:99.67% - >99.99%Forma y color:SolidPeso molecular:343.43PREP inhibitor-1
CAS:<p>PREP inhibitor-1 is a prolyl oligopeptidase (PREP) inhibitor for the study of Alzheimer's disease.</p>Fórmula:C22H28N4O2Pureza:98.78%Forma y color:SoildPeso molecular:380.48Obicetrapib
CAS:<p>Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.</p>Fórmula:C32H31F9N4O5Pureza:99.26% - >99.99%Forma y color:SolidPeso molecular:722.6Lapaquistat acetate
CAS:<p>Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor that reduces the cytotoxicity induced by statins in human skeletal muscle cells.</p>Fórmula:C33H41ClN2O9Pureza:99.38% - 99.94%Forma y color:SolidPeso molecular:645.14
