Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(271 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(98 productos)
- Lípido(58 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(165 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8628 productos de "Metabolismo"
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1,4-Dihydropyridine
<p>1,4-Dihydropyridine acts as an antagonist for calcium channels (calcium channel), specifically blocking the L-type calcium channels. This action reduces the influx of calcium ions into cardiac and vascular smooth muscle cells, consequently decreasing cardiac contractility and heart rate, dilating blood vessels, and lowering blood pressure.</p>Fórmula:C12H17NO4Forma y color:SolidPeso molecular:239.27Octanoyl Coenzyme A (sodium salt)
<p>Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.</p>Fórmula:C29H49N7NaO17P3SForma y color:SolidPeso molecular:915.71MeIQx
CAS:<p>MeIQx, a carcinogenic compound in cooked fish/meat, triggers DNA-reactive metabolites and rat tumors.</p>Fórmula:C11H11N5Forma y color:SolidPeso molecular:213.244Myoregulin
<p>Myoregulin (MLN peptide), a regulin family member, modulates muscle performance through intracellular calcium handling.</p>Fórmula:C239H391N53O67S3Pureza:98%Forma y color:SolidPeso molecular:5175.17MS-PPOH
CAS:<p>MS-PPOH is a potent and selective inhibitor of cytochrome P450 (CYP) epoxygenase. MS-PPOH inhibits CYP2C8 and CYP2C9 with IC50s of 15 and 11 µM, respectively</p>Fórmula:C16H21NO4SPureza:99.39%Forma y color:SolidPeso molecular:323.41Butyrolactone II
CAS:<p>Butyrolactone II is a useful organic compound for research related to life sciences. The catalog number is T124034 and the CAS number is 87414-44-6.</p>Fórmula:C19H16O7Forma y color:SolidPeso molecular:356.33α-Glucosidase-IN-78
<p>α-Glucosidase-IN-78 (Compound 12m) is a reversible competitive inhibitor of α-glucosidase (α-glucosidase) with an IC50 of 6.0 μM. Due to its blood sugar-lowering properties, α-Glucosidase-IN-78 is applicable in diabetes research.</p>Fórmula:C28H22N8O4Forma y color:SolidPeso molecular:534.526DSPE-PEG5000-ESBP
<p>DSPE-PEG5000-ESBP is a PEG compound composed of DSPE and E-selectin binding peptide (ESBP). Acting as a tumor-targeting peptide, ESBP has the ability to specifically recognize and bind to receptors or markers on the surface of tumor cells.</p>Forma y color:Odour SolidDSPE-PEG2000-octreotide
<p>DSPE-PEG2000-Octreotide is a PEG compound composed of DSPE and Octreotide. Octreotide serves as a somatostatin receptor agonist with antitumor properties, mediating apoptosis and applicable in acromegaly research. DSPE-PEG2000-Octreotide is employed in drug delivery systems.</p>Forma y color:Odour SolidDSPE-PEG2000-CCK8
<p>DSPE-PEG2000-CCK8 is a PEG compound comprising DSPE and Cholecystokinin-8 (CCK8). Cholecystokinin-8 exhibits peptide activity responsible for regulating gallbladder contractions and digestive system functions. DSPE-PEG2000-CCK8 is applicable for drug delivery.</p>Forma y color:Odour Solid[pTyr5] EGFR (988-993)
CAS:<p>'[pTyr5] EGFR (988-993) is a phosphorylated peptide from EGFR's Tyr992 site, often bound to inactive PTP1B.</p>Fórmula:C31H45N6O17PPureza:98%Forma y color:SolidPeso molecular:804.69Phenolic acid
CAS:<p>Phenolic acid is an endogenous metabolite.</p>Fórmula:C7H8D2O3Pureza:98%Forma y color:SolidPeso molecular:144.16Nor-Acetildenafil
CAS:<p>Nor-Acetildenafil is a derivative of Acetildenafil, a synthetic phosphodiesterase inhibitor.</p>Fórmula:C24H32N6O3Forma y color:SolidPeso molecular:452.555(S)-HETE
CAS:<p>5(S)-HETE, an endogenous metabolite found in the blood, is utilized in researching Rheumatoid Arthritis, Rhinitis, and Asthma [1] [2].</p>Fórmula:C20H32O3Forma y color:SolidPeso molecular:320.47PTP1B-IN-14
CAS:<p>PTP1B-IN-14 is a selective inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) that targets the allosteric site, exhibiting an inhibitory concentration (IC50)</p>Fórmula:C27H19N5O3S4Forma y color:SolidPeso molecular:589.73O-Desisobutyl-O-n-propyl Febuxostat
CAS:<p>O-Desisobutyl-O-n-propyl Febuxostat, an xanthine oxidase inhibitor.</p>Fórmula:C15H14N2O3SForma y color:SolidPeso molecular:302.35EC1454
CAS:EC1454 is an anti-tumor compound.Fórmula:C65H98N16O34SPureza:98%Forma y color:SolidPeso molecular:1679.635,6-Dihydro-2H-pyran-2-one
CAS:<p>5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.</p>Fórmula:C5H6O2Forma y color:SolidPeso molecular:98.1ecMetAP-IN-1
CAS:<p>ecMetAP-IN-1 可用作 QSAR 模型，以使用多元线性回归研究蛋氨酸氨基肽酶抑制剂作为抗癌剂。</p>Fórmula:C13H11N3Pureza:99.34%Forma y color:SolidPeso molecular:209.25PKM2-IN-10
PKM2-IN-10 is a PKM2 inhibitor. It effectively suppresses the proliferation of A549 and HCC1833 cell lines with IC50 values of 3.36 μM and 9.20 μM, respectively. PKM2-IN-10 demonstrates antitumor activity in human non-small cell lung cancer (NSCLC) and mouse lung adenocarcinoma models. It is applicable for research in lung cancer.Fórmula:C21H15F4N5Forma y color:SolidPeso molecular:413.12636Cy3 IRGD-PEG-DSPE
<p>Cy3 IRGD-PEG-DSPE is a PEG phospholipid containing Cy3 dye, applicable for protein/nucleic acid labeling and fluorescence microscopy. It self-assembles in aqueous solutions to form micelles or lipid bilayers, which are useful for creating liposomes or nanoparticles for the delivery of nutrients, such as mRNA or DNA vaccines.</p>Forma y color:Odour SolidIRC-083864
CAS:<p>IRC-083864 is a novel bis quinone CDC25 phosphatase active inhibitor against human cancer cells.</p>Fórmula:C28H25F2N5O5SForma y color:SolidPeso molecular:581.59PDE5-IN-11
<p>PDE5-IN-11 is a potent PDE5 inhibitor, exhibiting an IC50 of 40 nM, and also displays inhibitory activity against PDE4 and PDE6 with IC50 values of 1.78 μM and</p>Forma y color:Odour Solid1-Palmitoyl-2-linoleoyl PE
CAS:Phosphatidylethanolamine PLPE: a cell membrane component, studied for anandamide biosynthesis, sPLA2-IIA activity substrate.Fórmula:C39H74NO8PForma y color:SolidPeso molecular:715.994TAK-778
CAS:TAK-778, a derivative of ipriflavone, demonstrates the ability to stimulate bone growth in both in vitro and in vivo models.Fórmula:C24H28NO7PSPureza:98%Forma y color:SolidPeso molecular:505.52Digalacturonic acid
CAS:<p>Digalacturonic acid, a pectin metabolite, aids in enzyme co-crystallization like proteinase K.</p>Fórmula:C12H18O13Forma y color:SolidPeso molecular:370.26TEI-9648
CAS:<p>TEI-9648: Potent, specific VDR antagonist, blocks 1α,25(OH)2D3 effects, may aid bone metabolism study.</p>Fórmula:C27H38O4Forma y color:SolidPeso molecular:426.597γ-Globulins from human blood
CAS:<p>γ-Globulins, a protein fraction found in human blood, comprise a class of proteins with potent antibody activity that safeguards against bacterial and viral</p>Forma y color:Solidα-Glucosidase-IN-84
<p>α-Glucosidase-IN-84 (Compound 7j) is a competitive inhibitor of α-glucosidase, exhibiting an IC50 of 50 μM and a Ki of 32 μM. It shows potential for application in metabolic disease research, particularly in studies related to type 2 diabetes.</p>Fórmula:C25H29N7O3SForma y color:SolidPeso molecular:507.608α-Muricholic acid
CAS:<p>α-Muricholic acid is the most abundant primary bile acid in rodents.</p>Fórmula:C24H40O5Pureza:98%Forma y color:SolidPeso molecular:408.577-Hydroxymethotrexate
CAS:7-Hydroxymethotrexate, major Methotrexate metabolite, inhibits dihydrofolate reductase and DNA synthesis by blocking folic acid conversion.Fórmula:C20H22N8O6Pureza:99.72%Forma y color:SolidPeso molecular:470.44Herbicidal agent 6
<p>Herbicidal agent 6 (D15) functions as a Transketolase (TKL) inhibitor and exhibits herbicidal activity.</p>Forma y color:Odour SolidERAP1 modulator-1
CAS:<p>ERAP1 modulator-1 (Compound 1) is a regulator of endoplasmic reticulum aminopeptidase 1 (ERAP1) with an IC50 of less than 250 nM.</p>Fórmula:C23H23F3N2O5SForma y color:SolidPeso molecular:496.55-hydroxy Omeprazole
CAS:<p>5-hydroxy omeprazole, major omeprazole metabolite, formed by CYP2C19, affects gastric H+/K+ pump inhibition.</p>Fórmula:C17H19N3O4SForma y color:SolidPeso molecular:361.42C17 Sphingomyelin (d18:1/17:0)
CAS:<p>C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.</p>Fórmula:C40H81N2O6PForma y color:SolidPeso molecular:717.0513,14-dihydro Prostaglandin E1
CAS:<p>13,14-dihydro PGE1, a metabolite of PGE1, inhibits platelet aggregation and activates adenylate cyclase with IC50 of 31/21 nM and Kact 668 nM.</p>Fórmula:C20H36O5Forma y color:SolidPeso molecular:356.503PDE11A4-IN-1
<p>PDE11A4-IN-1 (compound 23b) is a potent, selective inhibitor of PDE11A4, demonstrating an IC50 of 12 nM and exhibiting high selectivity against PDE1, PDE2,</p>Forma y color:Odour SolidROS-IN-2
<p>ROS-IN-2 (compound 85), a seco-lupane triterpenoid derivative, inhibits reactive oxygen species (ROS) production and shields mitochondria from oxidative damage</p>Fórmula:C42H62ClNO8SPureza:98%Forma y color:SolidPeso molecular:776.46PDK-IN-2
<p>PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.</p>Fórmula:C17H23AsCl2N2O2S2Forma y color:SolidPeso molecular:497.33Propionylcarnitine
CAS:<p>Propionylcarnitine (Propionyl carnitine) is a widely used dietary supplement that has been associated with glaucoma and does it ruptu</p>Fórmula:C10H19NO4Pureza:99.69%Forma y color:SolidPeso molecular:217.26PBI-6DNJ
<p>PBI-6DNJ, an oral multivalent glycosidase inhibitor, has a K i of 0.14 μM against mouse α-glucosidase and aids type 2 diabetes research.</p>Fórmula:C120H146N26O36Forma y color:SolidPeso molecular:2528.6HIF1-IN-3
CAS:<p>HIF1-IN-3 (Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-) is an effective inhibitor of HIF-1 (EC50 = 0.9 μM) and can be used in</p>Fórmula:C26H24N2O3Pureza:99.59%Forma y color:SolidPeso molecular:412.48Sucrose phosphorylase
CAS:Sucrose phosphorylase, a bacterial enzyme, transforms sucrose and phosphate into α-D-glucose-1-phosphate and D-fructose.Forma y color:SolidDactylocycline A
CAS:<p>Dactylocyclines A: novel antibiotic from Dactylosporangium, effective against tetracycline-resistant microbes.</p>Fórmula:C31H40ClN3O13Pureza:98%Forma y color:SolidPeso molecular:698.11Creatine kinase (OcCK)
CAS:<p>Creatine kinase (OcCK) converts creatine and ATP into phosphocreatine and ADP, crucial for ATP/ADP balance during high energy demand.</p>Forma y color:SolidA3373
CAS:<p>A3373 is a novel inhibitor targeting both Phospholipase D1 (PLD1) and Phospholipase D2 (PLD2), demonstrating half maximal inhibitory concentrations (IC50) of</p>Fórmula:C17H9F7N2OPureza:98%Forma y color:SoildPeso molecular:390.26D-Sedoheptulose-7-phosphate (barium salt)
CAS:<p>D-Sedoheptulose-7-phosphate: Key in pentose phosphate path, carbon fixation, and compound biosynthesis.</p>Fórmula:C7H17BaO10PForma y color:SolidPeso molecular:429.504WAY-615145
CAS:WAY-615145 is a compound that activates glucokinase.Fórmula:C16H18N2OSPeso molecular:286.39ANK peptide
CAS:ANK peptide is a novel peptide designed based on the conserved residue of a single-anchored protein motif. It acts as an inhibitor of γ-synuclein (SNCG) by binding to SNCG, thereby competing with and disrupting the SNCG-BubR1 interaction. This action enhances the sensitivity of breast cancer cells to antimicrotubule agents such as nocodazole and paclitaxel. ANK peptide is useful for tumor research.Fórmula:C152H244N52O46S2Forma y color:SolidPeso molecular:3600.0115-keto Latanoprost (free acid)
CAS:<p>15-keto Latanoprost, a less potent metabolite and impurity of latanoprost, lowers intraocular pressure in monkeys and constricts pupils in cats.</p>Fórmula:C23H32O5Forma y color:SolidPeso molecular:388.5
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