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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8628 productos de "Metabolismo"

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  • Adenylosuccinic acid tetraammonium


    <p>Adenylosuccinic acid, orally active, is a purine ribonucleotide involved in nucleotide metabolism, may aid in DMD studies.</p>
    Fórmula:C14H30N9O11P
    Forma y color:Solid
    Peso molecular:531.42
  • Calcium gluconate monohydrate

    CAS:
    <p>Calcium gluconate monohydrate is a useful organic compound for research related to life sciences. The catalog number is T35350 and the CAS number is 66905-23-5.</p>
    Fórmula:C6H16CaO8
    Pureza:98%
    Forma y color:Solid
    Peso molecular:256.264
  • Amastatin hydrochloride

    CAS:
    <p>Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.</p>
    Fórmula:C21H39ClN4O8
    Forma y color:White To Off-White Powder
    Peso molecular:511.01
  • Carboxypeptidase B

    CAS:
    <p>Carboxypeptidase B degrades peptides from C-terminal, freeing amino acids, and targets basic residues.</p>
    Forma y color:Solid
  • DG013A formate


    <p>DG013A (formate) is a tripeptide-mimicking inhibitor of hypophosphorous acid. It exhibits IC50 values of 33 nM for ERAP1 and 11 nM for ERAP2. This compound can be utilized in research related to autoimmune diseases and cancer.</p>
    Fórmula:C27H37N4O4PCH2O2
    Forma y color:Solid
    Peso molecular:530.99
  • PBI-6DNJ


    <p>PBI-6DNJ, an oral multivalent glycosidase inhibitor, has a K i of 0.14 μM against mouse α-glucosidase and aids type 2 diabetes research.</p>
    Fórmula:C120H146N26O36
    Forma y color:Solid
    Peso molecular:2528.6
  • Ferroleuton


    <p>Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.</p>
    Fórmula:C13H16FeN2O2
    Forma y color:Solid
    Peso molecular:288.12
  • Lunine

    CAS:
    <p>Lunine is a bioactive chemical.</p>
    Fórmula:C16H17NO4
    Forma y color:Solid
    Peso molecular:287.31
  • CK1δ/CK1ε liagnd-1


    <p>CK1δ/CK1ε ligand-1 is a ligand of CK1δ/CK1ε and can serve as a target protein ligand for the synthesis of the CK1 PROTAC degrader AH078.</p>
    Fórmula:C21H20F2N6
    Forma y color:Solid
    Peso molecular:394.42
  • (S)-Higenamine

    CAS:
    <p>(S)-Higenamine, a benzylisoquinoline precursor, forms from dopamine and 4-HPAA via NCS.</p>
    Fórmula:C16H17NO3
    Forma y color:Solid
    Peso molecular:271.31
  • α-Amylase/α-Glucosidase-IN-17


    <p>α-Amylase/α-Glucosidase-IN-17 (Compound 3) is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 14.61 μM and 25.38 μM, respectively. It exhibits some inhibitory activity against A549 cancer cells and possesses both antitumor and antidiabetic properties.</p>
    Fórmula:C19H18FNO
    Forma y color:Solid
    Peso molecular:295.35
  • Galcuronokinase (AtGalAK)


    <p>AtGalAK, a GHMP kinase, converts d-GalA to GalA-1-P using ATP.</p>
    Forma y color:Solid
  • Estriol 16α-(β-D-glucuronide)

    CAS:
    <p>Estriol 16α-(β-D-glucuronide), an endogenous metabolite found in urine, is utilized in pregnancy research [1] [2].</p>
    Fórmula:C24H32O9
    Forma y color:Solid
    Peso molecular:464.51
  • Succinic acid tromethamine

    CAS:
    <p>Succinic acid tromethamine is an oral anxiolytic, TCA cycle intermediate, and key precursor in various industries.</p>
    Fórmula:C8H17NO7
    Forma y color:Solid
    Peso molecular:239.22
  • Digalacturonic acid

    CAS:
    <p>Digalacturonic acid, a pectin metabolite, aids in enzyme co-crystallization like proteinase K.</p>
    Fórmula:C12H18O13
    Forma y color:Solid
    Peso molecular:370.26
  • 20-hydroxy Prostaglandin E2

    CAS:
    20-hydroxy PGE2 is a cytochrome P450 metabolite of PGE2, formed via ω-oxidation and β-oxidation.
    Fórmula:C20H32O6
    Forma y color:Solid
    Peso molecular:368.46
  • 7β,25-Dihydroxycholesterol

    CAS:
    <p>7β,25-Dihydroxycholesterol, an endogenous metabolite, functions as chemoattractants for immune cells that express EBI2 [1].</p>
    Fórmula:C27H46O3
    Forma y color:Solid
    Peso molecular:418.65
  • iso-C15:0 3-OH

    CAS:
    Iso-C15:0 3-OH is a fatty acid that can be isolated from the PLRT strain. PLRT is a rod-shaped, Gram-negative, chemolithoheterotrophic, obligately aerobic bacterium, obtained from the feces of the mollusk Aplysia punctata.
    Fórmula:C15H30O3
    Forma y color:Solid
    Peso molecular:258.397
  • hCAII-IN-7


    <p>hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.</p>
    Fórmula:C20H25N3O4S
    Forma y color:Solid
    Peso molecular:403.5
  • Ftase inhibitor III

    CAS:
    <p>Ftase Inhibitor III, derived from a phenotypic screen, functions as an anion-dependent inhibitor of Farnesyltransferase.</p>
    Fórmula:C24H34N6O
    Forma y color:Solid
    Peso molecular:422.577
  • ACAT-IN-3

    CAS:
    <p>ACAT-IN-3, a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT), effectively suppresses NF-κB dependent transcription.</p>
    Fórmula:C25H36N2O6S
    Forma y color:Solid
    Peso molecular:492.63
  • Nucleoside hydrolase (IAGNH)

    CAS:
    <p>IAGNH, a glycosidase, breaks N-glycosidic bonds in nucleosides, recycling nucleobases and ribose.</p>
    Forma y color:Solid
  • Bicyclic UK18

    CAS:
    Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.
    Fórmula:C77H118N26O25S3
    Forma y color:Solid
    Peso molecular:1904.11
  • ANK peptide

    CAS:
    ANK peptide is a novel peptide designed based on the conserved residue of a single-anchored protein motif. It acts as an inhibitor of γ-synuclein (SNCG) by binding to SNCG, thereby competing with and disrupting the SNCG-BubR1 interaction. This action enhances the sensitivity of breast cancer cells to antimicrotubule agents such as nocodazole and paclitaxel. ANK peptide is useful for tumor research.
    Fórmula:C152H244N52O46S2
    Forma y color:Solid
    Peso molecular:3600.01
  • hMAO-B-IN-4

    CAS:
    <p>hMAO-B-IN-4 is a selective, reversible and blood–brain barrier (BBB) penetrable inhibitor of human monoamine oxidase-B (hMAO-B, IC50=0.067 μM, Ki= 0.03 μM, hMAO</p>
    Fórmula:C20H16O2S
    Pureza:99.8%
    Forma y color:Solid
    Peso molecular:320.4
  • UK140


    <p>UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.</p>
    Fórmula:C72H105N19O25S3
    Forma y color:Solid
    Peso molecular:1732.91
  • Cellulose

    CAS:
    <p>Cellulose, an excipient, aids stability, solubility, and processing of drugs and affects their ADME.</p>
    Fórmula:C12H22O11
    Forma y color:Solid
    Peso molecular:342.297
  • RSRGVFF


    <p>RSRGVFF (FOXP3 inhibitor P60) is a mixed angiotensin-converting enzyme (ACE) inhibitor with the ability to penetrate the blood-brain barrier, exhibiting an IC50 value of 5.01 μM. It binds to both active and inactive sites of ACE and its substrate HHL complex, thereby reducing the catalytic activity of ACE. RSRGVFF can be further explored for hypertension research.</p>
    Fórmula:C40H61N13O9
    Forma y color:Solid
    Peso molecular:867.994
  • C18:1 Ceramide (d18:1/18:1(9Z))

    CAS:
    <p>C18:1 Ceramide (d18:1/18:1(9Z)) is a ceramide, and C18:1-Ceramide levels are elevated in overweight and insulin-resistant , advanced ovarian cancer.</p>
    Fórmula:C36H69NO3
    Pureza:99.96%
    Forma y color:Solid
    Peso molecular:563.94
  • Anticancer agent 232


    Anticanceragent 232 (compound 12f) is a sugar hybrid designed from 1-azide glycosides derived from d-glucose, d-galactose, and d-mannose. The IC50 values for this compound are 1.05 μM against MCF-7 cells and 18.03 μM for MDA-MB231 cells.
    Fórmula:C32H31BrN4O11
    Peso molecular:726.11727
  • 4-Phytase

    CAS:
    <p>4-Phytase is a phosphohydrolase of inositol hexaphosphate [1] .</p>
    Forma y color:Solid
  • Febuxostat isopropyl isomer

    CAS:
    <p>Febuxostat isopropyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>
    Fórmula:C15H14N2O3S
    Forma y color:Solid
    Peso molecular:302.35
  • M145724

    CAS:
    M145724 ((3Z,6E)-1-N-Methylalbonoursin) is a metabolite that can be extracted from Streptomyces albus.
    Fórmula:C16H18N2O2
    Peso molecular:270.33
  • Glycodeoxycholic acid monohydrate

    CAS:
    <p>Glycodeoxycholic acid monohydrate is a nuclear receptor ligand.</p>
    Fórmula:C26H45NO6
    Forma y color:Solid
    Peso molecular:467.64
  • β-Galactose dehydrogenase

    CAS:
    Beta-Galactose dehydrogenase converts galactose to galactonolactone, reducing NAD to fluorescent NADH; useful in galactose measurement.
  • Remdesivir de(ethylbutyl 2-aminopropanoate)

    CAS:
    <p>Remdesivir impurity with antiviral activity; EC50: SARS-CoV/MERS-CoV 74 nM, murine hepatitis virus 30 nM. Effective against COVID-19 in vitro.</p>
    Fórmula:C18H18N5O7P
    Forma y color:Solid
    Peso molecular:447.34
  • Mono(5-carboxy-2-ethylpentyl) phthalate

    CAS:
    <p>MECPP is a metabolite of DEHP, a major plasticizer used in flexible PVC.</p>
    Fórmula:C16H20O6
    Forma y color:Solid
    Peso molecular:308.33
  • WAY-615145

    CAS:
    WAY-615145 is a compound that activates glucokinase.
    Fórmula:C16H18N2OS
    Peso molecular:286.39
  • Calcineurin Autoinhibitory Peptide

    CAS:
    <p>Selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 μM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 &gt; 100 mM).</p>
    Fórmula:C124H205N39O39S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2930.34
  • Z-Pro-prolinal

    CAS:
    <p>Z-Pro-prolinal, an orally active PREP inhibitor, IC50: 0.4 nM in porcine.</p>
    Fórmula:C18H22N2O4
    Forma y color:Solid
    Peso molecular:330.38
  • N-Nonyldeoxynojirimycin

    CAS:
    <p>N-Nonyldeoxynojirimycin (NN-DNJ) is an inhibitor of acid α-glucosidase and α-1,6-glucosidase (IC50s = 0.42 and 8.4 μM, respectively).</p>
    Fórmula:C15H31NO4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:289.41
  • Roridin L2

    CAS:
    <p>Roridin L2 is a natural product for research related to life sciences. The catalog number is T41264 and the CAS number is 85124-22-7.</p>
    Fórmula:C29H38O9
    Forma y color:Solid
    Peso molecular:530.614
  • C17 Sphingomyelin (d18:1/17:0)

    CAS:
    <p>C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.</p>
    Fórmula:C40H81N2O6P
    Forma y color:Solid
    Peso molecular:717.05
  • 7-Hydroxydichloromethotrexate

    CAS:
    <p>7-Hydroxydichloromethotrexate is a methotrexate metabolite.</p>
    Fórmula:C20H20Cl2N8O6
    Forma y color:Solid
    Peso molecular:539.33
  • BMS 195614

    CAS:
    <p>BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.</p>
    Fórmula:C29H24N2O3
    Pureza:97.7%
    Forma y color:Solid
    Peso molecular:448.51
  • Tyrosine decarboxylase

    CAS:
    <p>TDC, a PLP-dependent enzyme, removes carboxyl groups from tyrosine, producing tyramine and CO2, found in plants, insects, and microbes.</p>
    Forma y color:Solid
  • P-orlandin

    CAS:
    <p>P-orlandin, a fungal compound, blocks FREP1, halting P. falciparum's mosquito infection.</p>
    Fórmula:C22H18O8
    Forma y color:Solid
    Peso molecular:410.37
  • Lurasidone metabolite 14326

    CAS:
    <p>Lurasidone metabolite 14326, an active metabolite of the atypical antipsychotic Lurasidone, functions effectively in the body.</p>
    Fórmula:C28H36N4O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:508.68
  • Asperlactone

    CAS:
    <p>Asperlactone is a nematicidal, insecticidal, antibacterial, and antifungal polyketide metabolite produced from A. westerdijkiae.</p>
    Fórmula:C9H12O4
    Forma y color:Solid
    Peso molecular:184.191
  • 2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol

    CAS:
    <p>2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol is a triglyceride.</p>
    Fórmula:C57H96O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:877.37