Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(271 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(98 productos)
- Lípido(58 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(165 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8628 productos de "Metabolismo"
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Orotidine 5′-monophosphate
CAS:<p>Orotidine 5′-monophosphate, a pyrimidine ribonucleoside, functions as an endogenous metabolite in human, E.</p>Fórmula:C10H13N2O11PForma y color:SolidPeso molecular:368.191SX29
<p>SX29 is a non-competitive α-glucosidase inhibitor with oral activity, exhibiting an IC50 of 2.12 μM. It possesses hypoglycemic properties; oral administration of SX29 reduces blood glucose levels and enhances glucose tolerance in diabetic mice.</p>Forma y color:Odour SolidPLA2-IN-1
<p>PLA2-IN-1 (Compound 7) is a potent and selective inhibitor of phospholipase A (PLA2) with an IC50 value of 1 nM. It effectively inhibits PLA2-induced coagulation disorders in vitro and shows potential for use as an antidote for snake bites caused by cobra venom.</p>Forma y color:Odour SolidSB-435495 ditartrate
CAS:<p>SB-435495 ditartrate is a potent, selective, reversible, non-covalent, and orally active inhibitor of Lp-PLA2, demonstrating an IC50 value of 0.06 nM [1] [3].</p>Fórmula:C46H52F4N6O14SForma y color:SolidPeso molecular:1020.99γ-Globulins from human blood
CAS:<p>γ-Globulins, a protein fraction found in human blood, comprise a class of proteins with potent antibody activity that safeguards against bacterial and viral</p>Forma y color:SolidTetracosanoyl-sulfatide
CAS:<p>C24 3'-sulfo Galactosylceramide is a key myelin sulfatide, high in leukodystrophy patients, non-immunogenic compared to C24:1 variant.</p>Fórmula:C48H93NO11SForma y color:SolidPeso molecular:892.322-oxo Clopidogrel
CAS:<p>2-oxo Clopidogrel SR-121683 is a metabolite of Clopidogrel,catalyzed by P450 enzyme via CYP3A oxidation, ydrolysis to the active metabolite CAM.antithrombotic.</p>Fórmula:C16H16ClNO3SForma y color:SolidPeso molecular:337.82DSPE-PEG2000-YIGSR
<p>DSPE-PEG2000-YIGSR is a PEG compound composed of DSPE and the biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin-binding protein (LBP), enhancing the adhesion and proliferation of various cell types, including endothelial cells, fibroblasts, and smooth muscle cells. DSPE-PEG2000-YIGSR is applicable in drug delivery.</p>Forma y color:Odour SolidCytochrome P450 reductase
CAS:<p>Cytochrome P450 reductase, a NADPH-cytochrome reductase, facilitates an optimal conformation of aromatase for substrate binding [1].</p>Forma y color:SolidACAT-IN-7
CAS:<p>ACAT-IN-7 inhibits ACAT enzyme; blocks NF-κB mediated transcription.</p>Fórmula:C32H49N3O5SForma y color:SolidPeso molecular:587.82Tetrahydrothiophen-3-one
CAS:<p>Tetrahydrothiophen-3-one can be used as food spices.</p>Fórmula:C4H6OSPureza:98.67%Forma y color:LiquidPeso molecular:102.15Di-O-demethylcurcumin
CAS:<p>Di-O-demethylcurcumin (Bisdemethylcurcumin) is an intestinal metabolite of curcumin known for its neuroprotective properties.</p>Fórmula:C19H16O6Forma y color:SolidPeso molecular:340.33N-Acetyl-α-D-glucosamine 1-phosphate disodium
CAS:<p>N-Acetyl-α-D-glucosamine 1-phosphate disodium (GlcNAc-1-P), an anomeric sugar phosphate, plays a crucial role as an intermediate in the biosynthesis of N-linked</p>Fórmula:C8H15NNaO9PForma y color:SolidPeso molecular:323.17Poly(4-vinylphenol)
CAS:Poly(4-vinylphenol) is an endogenous metabolite.Fórmula:C10H17NOPureza:98%Forma y color:SolidPeso molecular:167.252ZINC77292789
CAS:ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) is a reagent for the preparation of a synthetic MUC1 Glycopeptide Bearing βGalNAc-Thr as a Tn antigen isomer whichFórmula:C33H38N2O13Pureza:99.24%Forma y color:SolidPeso molecular:670.66Fumonisin B2
CAS:<p>Fumonisin B2, from Fusarium moniliforme in grains, blocks ceramide synthase, disrupting sphingolipid biosynthesis.</p>Fórmula:C34H59NO14Pureza:98%Forma y color:SolidPeso molecular:705.83DM-CO-(CH2)5-SMe
CAS:<p>DM-CO-(CH2)5-SMe, derived from an antibody-drug conjugate (ADC) metabolite, serves as an anticancer agent with demonstrated cytotoxicity against H1703, H1975,</p>Fórmula:C39H56ClN3O10SForma y color:SolidPeso molecular:794.39Adefovir diphosphate 2TEA
<p>Adefovir diphosphate 2TEA,a metabolite of Adefovir, an oral reverse transcriptase inhibitor with antiviral activity against herpes, hepatitis B, and HIV.</p>Fórmula:C20H43N7O7P2Pureza:98.33%Forma y color:SolidPeso molecular:555.55Chlorothiazide
CAS:<p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>Fórmula:C7H6ClN3O4S2Pureza:98.46% - 98.91%Forma y color:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecular:295.72Geranylgeranyl pyrophosphate
CAS:<p>Geranylgeranyl pyrophosphate: a metabolite for protein modification and diterpenoid precursor, used in cancer research.</p>Fórmula:C20H36O7P2Forma y color:SolidPeso molecular:450.44hDHODH-IN-13
CAS:<p>hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in</p>Forma y color:SoildRORγ inverse agonist 1
CAS:<p>RORγ inverse agonist 1 has anti-inflammatory activity and can be used to treat rheumatism and psoriasis.</p>Fórmula:C22H20F3N3O3SPureza:99.68%Forma y color:SolidPeso molecular:463.47γ-glutamyltransferase
CAS:<p>γ-glutamyltransferase (GGT) is an enzyme located on the outer surface of the cell membrane. It maintains physiological concentrations of intracellular glutathione and cellular defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase can be utilized as a biomaterial or organic compound in life science-related research.</p>Forma y color:SolidPDE2A-IN-1
CAS:<p>PDE2A-IN-1 is a phosphodiesterase 2A (PDE2A) inhibitor with an IC 50 value of 1.3 nM.</p>Fórmula:C23H22F2N6Forma y color:SolidPeso molecular:420.468Sphingomyelin phosphodiesterase
CAS:<p>Sphingomyelin phosphodiesterase, a hydrolase, converts sphingomyelin into phosphocholine and ceramide, affecting cellular processes and cholesterol metabolism.</p>Forma y color:SolidPKM2-IN-4
<p>Compound 5C, referred to as Pkm2-in-4, is a selective PKM2 inhibitor (IC50 = 0.35 µM) that modulates pyruvate-dependent respiration and promotes mitochondrial</p>Fórmula:C15H17BrClNO3SeForma y color:SolidPeso molecular:453.62Validamine
CAS:<p>Validamine is a natural pseudo-aminosugar.</p>Fórmula:C7H15NO4Pureza:98%Forma y color:White PowderPeso molecular:177.2SHO1122147
<p>SHO1122147 (Compound 7m) disrupts the mitochondrial electron transport chain, demonstrating mitochondrial uncoupling activity (EC50=3.6 μM). It increases the cellular oxygen consumption rate (OCR=69%) and enhances cellular respiration. Additionally, SHO1122147 is orally active and can be utilized in research related to obesity and metabolic dysfunction-associated steatohepatitis (MASH).</p>Fórmula:C17H11ClN4O2Forma y color:SolidPeso molecular:338.748MS1262-C3-amide-C10-amine
<p>MS1262-C3-amide-C10-amine is an E3 Ligase Ligand-Linker conjugate. It includes a GLP ligand targeting the E3 ligase SPOP and a PROTAC linker. This compound can be utilized in designing PROTACs such as example [MS479].</p>Forma y color:Odour Solid2,5-Anhydro-D-glucitol-1,6-diphosphate
CAS:<p>2,5-Anhydro-D-glucitol-1,6-diphosphate mildly stimulates yeast Pyruvate Kinase; it's an analogue of a potent activator.</p>Fórmula:C6H14O11P2Forma y color:SolidPeso molecular:324.12TKL-IN-1
<p>TKL-IN-1 (compound 7r) serves as an inhibitor of transketolase (Transketolase) and can be utilized as an herbicide. This compound effectively hampers the growth of Digitaria sanguinalis (Ds) and Amaranthus retroflexus (Ar).</p>Fórmula:C20H12ClN5OS2Forma y color:SolidPeso molecular:437.93CALP3 TFA(261969-05-5 free base)
<p>CALP3 TFA is a potent Ca2+ channel blocker that activates EF-hand motifs of Ca2+-binding proteins.</p>Fórmula:C46H69F3N10O11Pureza:98%Forma y color:SolidPeso molecular:995.1L-Pyroglutamic acid β-naphthylamide
CAS:<p>L-Pyroglutamic acid β-naphthylamide (PYR) is a derivative of glutamic acid.</p>Fórmula:C15H14N2O2Forma y color:SolidPeso molecular:254.28N1-Acetylspermine
CAS:<p>N1-Acetylspermine, an endogenous metabolite found in urine, has applications in leukemia research [1] [2].</p>Fórmula:C12H28N4OForma y color:SolidPeso molecular:244.38SHP2 protein degrader-2
CAS:SHP2 protein degrader-2 (SHP2-D26), a PROTAC degrader targeting the SHP2 protein, effectively diminishes its expression levels across various cancer cell typesFórmula:C56H79ClN12O6S2Forma y color:SolidPeso molecular:1115.89N-Acetyl-Ser-Asp-Lys-Pro TFA
N-Acetyl-Ser-Asp-Lys-Pro (TFA), a bone marrow tetrapeptide, is a specific ACE substrate for angiotensin conversion.Fórmula:C22H34F3N5O11Pureza:98%Forma y color:SolidPeso molecular:601.53tetranor-PGEM
CAS:<p>Tetranor-PGEM, the primary urinary byproduct of PGE1 and PGE2, marks PGE2 production; humans excrete 7-40 μg daily.</p>Fórmula:C16H24O7Forma y color:SolidPeso molecular:328.361Methyl 3,4,5-trimethoxy-2-(2-(nicotinamido)benzamido)benzoate
CAS:<p>Preterramide C is a fungal metabolite that has been found inA.</p>Fórmula:C24H23N3O7Forma y color:SolidPeso molecular:465.46Angiotensin pentapeptide
CAS:<p>Angiotensin pentapeptide is a peptide.</p>Fórmula:C35H45N7O7Pureza:98%Forma y color:SolidPeso molecular:675.77Maximiscin
CAS:<p>Maximiscin, a metabolite derived from fungi, causes DNA damage and exhibits selective cytotoxic activity towards a specific subtype of triple-negative breast</p>Fórmula:C23H31NO8Forma y color:SolidPeso molecular:449.49Nampt-IN-10 trihydrochloride
<p>Nampt-IN-10 trihydrochloride, a NAMPT inhibitor, is effective on A2780 & CORL23 cells (IC50: 5/19 nM); potential ADC payload.</p>Fórmula:C27H31Cl3FN5O2Forma y color:SolidPeso molecular:582.921-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol
CAS:<p>1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol is an intrinsic metabolite and a component of the cell membrane [1].</p>Fórmula:C47H83O13PForma y color:SolidPeso molecular:887.13Amiquinsin hydrochloride monohydrate
CAS:<p>Amiquinsin hydrochloride monohydrate is a compound known for its antihypertensive activity. It undergoes metabolism in the body, with its primary metabolite being 4-amino-6,7-dimethoxy-3-quinolineol hydrochloride monohydrate.</p>Fórmula:C11H15ClN2O3Forma y color:SolidPeso molecular:258.7[(3R)-3-Hydroxydodecanoyl]-L-carnitine
CAS:<p>[(3R)-3-Hydroxydodecanoyl]-L-carnitine is an endogenous metabolite[1].</p>Fórmula:C19H37NO5Forma y color:SolidPeso molecular:359.50Phosphate acetyltransferase
CAS:Phosphate acetyltransferase, an enzyme, reversibly transfers acetyl groups to CoA, aiding in acetate assimilation/dissimilation.Forma y color:Solid2-Hydroxyquinoline
CAS:<p>Compound PDK0291, with CAS No. 59-31-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0291 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C9H7NOForma y color:White SolidPeso molecular:145.15Aspercolorin
CAS:<p>Aspercolorin is a fungal metabolite produced by Aspergillus.</p>Fórmula:C25H28N4O5Forma y color:SolidPeso molecular:464.51DSPE-PEG5000-YIGSR
<p>DSPE-PEG5000-YIGSR is a PEG compound comprised of DSPE and the biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin-binding protein (LBP), enhancing the adhesion and proliferation of various cell types, such as endothelial cells, fibroblasts, and smooth muscle cells. DSPE-PEG5000-YIGSR is applicable for drug delivery.</p>Forma y color:Odour SolidMDNI-caged-L-glutamate
CAS:<p>MDNI-glu: photosensitive, bio-inert L-glutamate derivative with enhanced light utilization.</p>Fórmula:C14H16N4O8Forma y color:SolidPeso molecular:368.3021-Naphthyl 3,5-dinitrobenzoate
CAS:<p>1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.</p>Fórmula:C17H10N2O6Pureza:99.79%Forma y color:SolidPeso molecular:338.27
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