Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(270 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(33 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(97 productos)
- Lípido(59 productos)
- Lipoxigenasa(125 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8625 productos de "Metabolismo"
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Tibenelast
CAS:<p>Tibenelast is a cioactive chemical.</p>Fórmula:C13H14O4SForma y color:SolidPeso molecular:266.31FUT8-IN-1
<p>FUT8-IN-1 (Compound 37) is an inhibitor of α-1,6-fucosyltransferase (FUT8), with a dissociation constant (KD) of 49 nM and an IC50 around 50 µM. In the presence of FUT8, FUT8-IN-1 forms a highly active naphthoquinone imine intermediate, thereby inhibiting FUT8's enzymatic activity.</p>Fórmula:C23H25ClN2OForma y color:SolidPeso molecular:380.91Arginase
CAS:<p>Arginase (L-Arginine amidinase) is a key hydrolytic enzyme in the urea cycle, which hydrolyzes L-arginine into urea and L-ornithine.</p>Forma y color:Solid2-Chlorophenylboronic acid
CAS:<p>2-Chlorophenylboronic acid: A monohalogenated phenylboronic acid used in drug synthesis and as a fatty acid amidase inhibitor.</p>Fórmula:C6H6BClO2Pureza:99.42%Forma y color:SolidPeso molecular:156.37Sphingolipid ceramide N-deacylase (SCDase)
CAS:<p>SCDase splits fatty acids from sphingosine in glycosphingolipids, forming lysoglycosphingolipids.</p>Forma y color:SolidSB-435495 hydrochloride
CAS:<p>SB-435495 hydrochloride is a potent, selective, reversible, non-covalent, and orally active inhibitor of Lp-PLA2, exhibiting an IC50 of 0.06 nM [1] [3].</p>Fórmula:C38H41ClF4N6O2SForma y color:SolidPeso molecular:757.28ATP ditromethamine
CAS:<p>ATP ditromethamine is key for energy storage, metabolism, and acts as a coenzyme and signaling molecule in immunity and inflammation.</p>Fórmula:C18H38N7O19P3Forma y color:SolidPeso molecular:749.45Concizumab
CAS:<p>Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, thereby blocking the</p>Pureza:> 95%Forma y color:LiquidPeso molecular:145.76 kDaUDP-sugar pyrophosphorylase (BlUSP)
CAS:<p>BlUSP enzyme turns Glc-1-P into UDP-Glucose, transferring uridyl from UTP and producing PPi.</p>Forma y color:Solid12-Hydroxynevirapine
CAS:<p>12-Hydroxynevirapine, major Nevirapine metabolite; non-toxic but liver/skin SULTs convert it to reactive 12-Sulphoxy-nevirapine.</p>Fórmula:C15H14N4O2Forma y color:SolidPeso molecular:282.3Calcium Channel antagonist 4
CAS:<p>Calcium Channel antagonist 4 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).</p>Fórmula:C23H26N2O4SPureza:98.09%Forma y color:SolidPeso molecular:426.53Casein kinase 1δ-IN-14
CAS:<p>Casein kinase 1δ-IN-14 (WAY-637081) can be used to study atherosclerosis-related cardiovascular disease.</p>Fórmula:C17H11ClN4O2Pureza:99.74%Forma y color:SolidPeso molecular:338.75Motapizone
CAS:<p>Motapizone (NAT 05-239), a PDE3 inhibitor, moderates LPS-induced cytokine release and blocks platelet aggregation by boosting cAMP.</p>Fórmula:C12H12N4OSForma y color:SolidPeso molecular:260.32Estriol 3-glucuronide
CAS:<p>Estriol-3-glucuronide, a natural compound found in urine, is also present in amniotic fluid during normal pregnancy [1][2].</p>Fórmula:C24H32O9Forma y color:SolidPeso molecular:464.511Diacetinase
<p>Diacetinase, a member of the esterase family, catalyzes the hydrolysis of glyceryl diacetate (Diacetin). It is utilized in the measurement of lipase activity.</p>Forma y color:Odour SolidOsmanthuside H
CAS:<p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>Fórmula:C19H28O11Forma y color:SolidPeso molecular:432.422PDE4-IN-13
<p>PDE4-IN-13 is a phosphodiesterase 4 (PDE4) inhibitor exhibiting anti-inflammatory and antioxidant activities, with an half maximal inhibitory concentration (</p>Fórmula:C20H20O5Forma y color:SolidPeso molecular:340.37HLF1-11
CAS:<p>HLF1-11: human lactoferrin peptide, antimicrobial, inhibits MPO, steers monocytes to macrophages, boosts immunity.</p>Fórmula:C56H95N25O14SForma y color:SolidPeso molecular:1374.586β-hydroxy Eplerenone
CAS:<p>6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone .1 It is formed from eplerenone by the cytochrome P450 (CYP</p>Fórmula:C24H30O7Forma y color:SolidPeso molecular:430.497DSPE-PEG2000-CREKA
<p>DSPE-PEG3000-CREKA is a PEG compound composed of DSPE and the fibrin-targeting peptide (CREKA). The CREKA peptide targets tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3000-CREKA is useful in drug delivery applications.</p>Forma y color:Odour SolidBoc-Glu(OBzl)-OH
CAS:<p>Boc-Glu(OBzl)-OH (Boc-Glu(OBzl)-OH) is an Glutamic acid derivative.</p>Fórmula:C17H23NO6Pureza:98.11%Forma y color:SolidPeso molecular:337.37RORγ allosteric probe-1
CAS:RORγ Allosteric Probe-1 (Compound 12h), with excitation and emission wavelengths of 490/524 nm respectively, serves as an allosteric fluorescent probe for investigating RORγ allosteric inhibitors and the function of RORγ [1].Fórmula:C50H37ClF3N5O11SPeso molecular:1008.3724,25-Epoxycholesterol
CAS:24,25-Epoxycholesterol is an oxysterol agonist of the liver X receptor, known to inhibit the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) in hepatic cells. Additionally, 24,25-Epoxycholesterol plays a role in regulating cholesterol metabolism within the liver.Fórmula:C27H44O2Peso molecular:400.64α-Glucosidase-IN-79
<p>α-Glucosidase-IN-79 (Compound 4d9) is a non-competitive α-glucosidase inhibitor with an IC50 of 2.11 μM, demonstrating greater inhibitory potency than the existing α-glucosidase inhibitors Acarbose (IC50 of 327.0 μM) and HXH8r (IC50 of 15.32 μM). It exhibits no cytotoxicity on normal human liver cells (LO2) and shows good metabolic stability in rat plasma. α-Glucosidase-IN-79 holds promise for research in type 2 diabetes.</p>Fórmula:C21H22N2O5SForma y color:SolidPeso molecular:414.47511β-HSD1 inibitor 17
CAS:<p>11β-HSD1 inibitor 17 is an inhibitor of 11β-hydroxysteroid dehydrogenase (11β-HSD1).</p>Fórmula:C22H20F3N3O2SPureza:99.26% - 99.72%Forma y color:SoildPeso molecular:447.471-Palmitoyl-2-hydroxy-sn-glycero-3-PE
CAS:<p>1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid and endogenous metabolite used in biochemical experiments</p>Fórmula:C21H44NO7PPureza:99.82%Forma y color:SolidPeso molecular:453.55AY 9944 dihydrochloride
CAS:<p>AY 9944 dihydrochloride is a intermediate.</p>Fórmula:C22H30Cl4N2Pureza:99.22% - 99.82%Forma y color:SoildPeso molecular:464.3Cholesterol nervonate
CAS:<p>Cholesterol nervonate is a cholesterol ester found in human meibum, used experimentally in synthetic liposomes for biophysics and drug delivery research.</p>Fórmula:C51H90O2Forma y color:SolidPeso molecular:735.26DPP IV/hCA II-IN-1
CAS:<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Fórmula:C17H20N2O5SForma y color:SolidPeso molecular:364.422-Hydroxy atorvastatin lactone
CAS:<p>2-Hydroxy atorvastatin lactone, a metabolite of Atorvastatin, is an orally active HMG-CoA reductase inhibitor that efficiently reduces blood lipids [1][2].</p>Fórmula:C33H33FN2O5Forma y color:SolidPeso molecular:556.62Tpp-CAQK
<p>Tpp-CAQK, a specially engineered mitochondrial compound, has been shown to improve phagocytosis of myelin debris by macrophages, reduce mitochondrial dysfunction and pro-inflammatory features, and enhance tissue repair and functional recovery in mice after spinal cord injury.</p>Fórmula:C40H54BrN6O7PSForma y color:SolidPeso molecular:873.84UDP-α-D-Glucose sodium hydrate
<p>UDP-α-D-Glucose sodium hydrate is an endogenous metabolite and a pyrimidine nucleotide sugar, involved in glycosylation reactions during metabolic</p>Fórmula:C15H24N2Na2O18P2Forma y color:SolidPeso molecular:628.28Dihydrocarminomycin
CAS:<p>Dihydrocarminomycin is an anthracycline antibiotics.</p>Fórmula:C26H29NO10Pureza:98%Forma y color:SolidPeso molecular:515.515Coproporphyrin III
CAS:<p>Coproporphyrin III is a derivative of porphyrin.</p>Fórmula:C36H38N4O8Pureza:98%Forma y color:Purple XtlPeso molecular:654.72Hydroorotic acid
CAS:<p>Hydroorotic acid（Dihydroorotic acid） is an endogenous metabolite，a potential biomarker for diabetic nephropathy and adrenal pheochromocytoma.</p>Fórmula:C5H6N2O4Pureza:99.90%Forma y color:SolidPeso molecular:158.11Ninopterin
CAS:<p>Ninopterin is an experimental antineoplastic and folic acid analog.</p>Fórmula:C20H21N7O6Pureza:98%Forma y color:SolidPeso molecular:455.42(5S)-Neosamine C
CAS:<p>(5S)-Neosamine C, an aminocyclic alcohol antibiotic derived from microbial secondary metabolites, possesses a cyclized structure and is utilized in the biosynthesis of Neomycins.</p>Fórmula:C6H14N2O4Forma y color:SolidPeso molecular:178.19Venetoclax N-oxide
CAS:<p>Venetoclax N-oxide is a byproduct of potent, oral Bcl-2 inhibitor Venetoclax (ABT-199/GDC-0199) with Ki <0.01 nM.</p>Fórmula:C45H50ClN7O8SForma y color:SolidPeso molecular:884.44DSPE-PEG5000-R8
<p>DSPE-PEG5000-R8 is a PEG compound composed of DSPE and the cell-penetrating peptide (R8). It is utilized for drug delivery applications.</p>Forma y color:Odour Solid9(R)-HODE cholesteryl ester
CAS:<p>9(R)-HODE cholesteryl ester, from atherosclerotic lesions, may form enzymatically or by lipid peroxidation; used as a chiral analysis standard.</p>Fórmula:C45H76O3Forma y color:SolidPeso molecular:665.11-(2-Quinoxalinyl)-1,2,3,4-butanetetrol
CAS:<p>1-(2-Quinoxalinyl)-1,2,3,4-butanetetrol is a quinoxaline derivative and endogenous metabolite applicable to biochemical experiments and drug synthesis research.</p>Fórmula:C12H14N2O4Pureza:99.49%Forma y color:SolidPeso molecular:250.25BAY-277
<p>BAY-277 is a degrader of METAP2, with IC50 values of 5.8 nM for human METAP2 (hMETAP2) and 5.9 nM for mouse METAP2 (mMETAP2).</p>Fórmula:C44H52N8O5Forma y color:SolidPeso molecular:772.93β-1,4-GALT1-IN-1
<p>β-1,4-GALT1-IN-1 (Compound 6) is a β-1,4-GALT1 inhibitor with an IC50 value of 6.2 μM. It is applicable in studying various pathological conditions, including cancer, autoimmune diseases, and viral infections.</p>Fórmula:C29H23NO10Forma y color:SolidPeso molecular:545.494CK1δ/CK1ε liagnd-1
<p>CK1δ/CK1ε ligand-1 is a ligand of CK1δ/CK1ε and can serve as a target protein ligand for the synthesis of the CK1 PROTAC degrader AH078.</p>Fórmula:C21H20F2N6Forma y color:SolidPeso molecular:394.42Trichodecenin I
CAS:<p>Trichodecenin I is a peptaibol isolated from Trichoderma viride.</p>Fórmula:C38H69N7O8Pureza:98%Forma y color:SolidPeso molecular:752.011Hydroxypyruvic acid
CAS:<p>Hydroxypyruvic acid: a metabolic intermediate for glycine, serine, threonine; used by serine-pyruvate aminotransferase, glyoxylate reductase.</p>Fórmula:C3H4O4Pureza:98%Forma y color:SolidPeso molecular:104.06CooP
CAS:<p>CooP is a nonapeptide targeting glioblastoma. It binds to FABP3 for chemotherapy delivery.</p>Fórmula:C32H57N9O11SForma y color:SolidPeso molecular:775.91(±)16-HDHA
CAS:<p>(±)16-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro.</p>Fórmula:C22H32O3Forma y color:SolidPeso molecular:344.495α-Amylase-IN-11
<p>α-Amylase-IN-11 (compound C5f) is an α-amylase inhibitor with an IC50 of 0.56 μM, effective in reducing glucose levels in vivo. Additionally, it exhibits moderate inhibitory activity against α-glucosidase with an IC50 of 11.03 μM. In mouse models, α-Amylase-IN-11 significantly decreases glucose concentrations, indicating its potential for diabetes research.</p>Fórmula:C22H18N4OSForma y color:SolidPeso molecular:386.471-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine
CAS:<p>An endogenous blood metabolite, 1-heptadecanoyl-glycerophosphocholine, researches pregnancy/sepsis.</p>Fórmula:C25H52NO7PForma y color:SolidPeso molecular:509.66
