Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(178 productos)
- Caseína quinasa(130 productos)
- DHFR(33 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(269 productos)
- FAAH(64 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(32 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(54 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(97 productos)
- Lípido(59 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8626 productos de "Metabolismo"
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NADP+ (sodium salt hydrate)
CAS:<p>NADP+ is the oxidized cofactor form of NADPH, vital for cell survival, redox balance, and signaling; synthesized from NAD+ and ATP.</p>Fórmula:C21H30N7NaO18P3Forma y color:SolidPeso molecular:784.413Pantothenoylcysteine
CAS:<p>Pantothenoylcysteine is a bioactive chemical.</p>Fórmula:C12H22N2O6SForma y color:SolidPeso molecular:322.38N4-Acetylcytidine triphosphate sodium
CAS:<p>N4-Acetylcytidine triphosphate sodium is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription.</p>Fórmula:C11H18N3Na4O15P3Pureza:98%Forma y color:SolidPeso molecular:617.15PF-03049423
CAS:<p>PF-03049423: potent, selective PDE-5A inhibitor, IC50 ~0.2 nM, for rat/human thrombomodulin; used in ischemic stroke research.</p>Fórmula:C24H32N6O4Pureza:99.89% - 99.93%Forma y color:SolidPeso molecular:468.55ESI1
<p>ESI1 is a small molecule inhibitor of epigenetic silencing. This compound induces the formation of nuclear aggregates of the key lipid metabolism regulator SREBP1/2, thereby concentrating transcription co-activators to drive lipid/cholesterol biosynthesis. Additionally, ESI1 promotes myelin regeneration in demyelination animal models and facilitates de novo myelination on regenerating CNS axons, reversing age-related cognitive decline.</p>Fórmula:C18H18ClN5OForma y color:SolidPeso molecular:355.82(±)9-HODE cholesteryl ester
CAS:<p>(±)9-HODE cholesteryl ester was originally extracted from atherosclerotic lesions and shown to be produced by Cu2+-catalyzed oxidation of LDL.</p>Fórmula:C45H76O3Forma y color:SolidPeso molecular:665.11-Palmitoyl-2-linoleoyl PE
CAS:<p>Phosphatidylethanolamine PLPE: a cell membrane component, studied for anandamide biosynthesis, sPLA2-IIA activity substrate.</p>Fórmula:C39H74NO8PForma y color:SolidPeso molecular:715.994Malate dehydrogenase
CAS:<p>Malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1] .</p>Forma y color:SolidL-Lactic acid-13C3
CAS:<p>L-Lactic acid-13C3 is a stable isotope labeled L-Lactic acid analog. L-Lactic acid-13C3 can be used for lactate metabolism research.</p>Fórmula:C3H6O3Forma y color:SolidPeso molecular:93.055Diadenosine pentaphosphate pentalithium
CAS:<p>Endogenous vasoactive compound, found in platelets and brain cells, part of diadenosine polyphosphates (ApnA, n=2–7).</p>Fórmula:C20H24Li5N10O22P5Forma y color:SolidPeso molecular:946.03Rubratoxin B
CAS:<p>Rubratoxin B is a mycotoxin that causes hypoglycemia and fatty liver and has exhibited anticancer activity.</p>Fórmula:C26H30O11Pureza:98%Forma y color:Long Lathes; Hexagonal Plates From Amyl Acetate SolidPeso molecular:518.51Desoxycarbadox
CAS:<p>Desoxycarbadox, derived from Carbadox, is a quinoxaline-di-N-oxide antibiotic compound.</p>Fórmula:C11H10N4O2Forma y color:SolidPeso molecular:230.227Angiotensinogen (1-14), human TFA
<p>Angiotensinogen (1-14), human TFA is a fragment of the renin substrate angiotensinogen. Angiotensinogen is a precursor for all angiotensin peptides.</p>Fórmula:C85H123N24F3O21Pureza:98%Forma y color:SolidPeso molecular:1874.0611-trans Leukotriene C4
CAS:<p>11-trans LTC4 is a C-11 isomer of LTC4, forms slowly on storage, is less common but similarly potent in contractions, pKis: 6.42 (LTC4), 6.58 (11-trans).</p>Fórmula:C30H47N3O9SForma y color:SolidPeso molecular:625.78Edoxaban impurity 6
CAS:<p>Edoxaban impurity 6 is a byproduct of the anticoagulant Edoxaban, a potent oral factor Xa inhibitor with Kis of 0.561 nM. Used to prevent stroke.</p>Fórmula:C16H22ClN5O3Forma y color:SolidPeso molecular:367.83D-Lactate dehydrogenase
CAS:<p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>Forma y color:SolidGlycerol-3-phosphate dehydrogenase
CAS:<p>Glycerol-3-phosphate dehydrogenase from Saccharomyces cerevisiae is an enzyme that catalyzes the oxidation of glycerol-3-phosphate (G3P) to dihydroxyacetone phosphate (DHAP), playing a crucial role in glycerol metabolism and energy production. This enzyme acts as the rate-limiting step in glycerol production within Saccharomyces cerevisiae, regulating glycerol formation and accumulation to aid the yeast in adapting to hyperosmotic environments. Additionally, glycerol-3-phosphate dehydrogenase from Saccharomyces cerevisiae is relevant in research within the field of metabolic engineering.</p>Forma y color:SolidDiglycyl-histidine
CAS:<p>Diglycyl-histidine is a tripeptide complexed with cupric ion designed to mimic specific Cu(II) transport site of ascorbate on albumin molecule.</p>Fórmula:C10H15N5O4Forma y color:SolidPeso molecular:269.26Diacetinase
<p>Diacetinase, a member of the esterase family, catalyzes the hydrolysis of glyceryl diacetate (Diacetin). It is utilized in the measurement of lipase activity.</p>Forma y color:Odour SolidCarbonic anhydrase inhibitor 32
<p>Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.</p>Fórmula:C17H16N6O3SForma y color:SolidPeso molecular:384.41Silodosin Glucuronide (sodium salt)
CAS:<p>Active metabolite of silodosin, silodosin glucuronide is made by UGT2B7, toxic to rats (LD50: 0.347 mg/kg).</p>Fórmula:C31H39F3N3NaO10Forma y color:SolidPeso molecular:693.64Calcitriol Derivatives
<p>Calcitriol Derivatives is an analog of vitamin D3.</p>Fórmula:C30H47NO3Pureza:98%Forma y color:SolidPeso molecular:469.7KKII5
CAS:<p>KKII5 is a potent inhibitor of the lipoxygenase LOX-1 with an IC50 of 19 μM.KKII5 inhibits lipid peroxidation and enhances the ability of the active centers of</p>Fórmula:C16H14N2SPureza:99.34%Forma y color:SolidPeso molecular:266.36Zaragozic acid D(2)
CAS:<p>Zaragozic acid D(2) inhibits squalene synthase and ras farnesyl-protein transferase isolated from the keratinophilic fungus Amauroascus niger.</p>Fórmula:C36H50O14Pureza:98%Forma y color:SolidPeso molecular:706.77Pregnant mare serum gonadotropin
CAS:<p>Pregnant mare serum gonadotropin (PMSG) functions as a gonadotropin that enhances follicular development and ovulation in animals. This compound operates by modulating blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. Commonly employed in livestock to boost reproductive efficiency, PMSG is also valuable for research focused on estrous cycle regulation.</p>Forma y color:Solid19,20-Epoxycytochalasin D
CAS:<p>Fungal metabolite 19,20-Epoxycytochalasin D from Nemania sp. kills P. falciparum; non-toxic to Vero, toxic to BT-549, LLC-PK11, P388 cells.</p>Fórmula:C30H37NO7Forma y color:SolidPeso molecular:523.626Cy3 IRGD-PEG-DSPE
<p>Cy3 IRGD-PEG-DSPE is a PEG phospholipid containing Cy3 dye, applicable for protein/nucleic acid labeling and fluorescence microscopy. It self-assembles in aqueous solutions to form micelles or lipid bilayers, which are useful for creating liposomes or nanoparticles for the delivery of nutrients, such as mRNA or DNA vaccines.</p>Forma y color:Odour SolidSorbitol-6-phosphate 2-dehydrogenase
CAS:<p>Sorbitol-6-phosphate 2-dehydrogenase, a dehydrogenase enzyme produced by Escherichia coli, catalyzes the interconversion of D-sorbitol 6-phosphate and D-fructose 6-phosphate. The enzyme oxidizes D-sorbitol 6-phosphate at a rate ten times faster than it reduces D-fructose 6-phosphate, playing a role in various cellular processes.</p>Forma y color:Solid12α-Hydroxysteroid dehydrogenase
CAS:<p>12α-Hydroxysteroid dehydrogenase, an NAD-dependent enzyme expressed in Bacillus sphaericus, actively processes both free and conjugated bile salts. It is utilized to determine the levels of 12α-hydroxy bile acids in serum.</p>Forma y color:SolidDSPE-PEG5000-CREKA
<p>DSPE-PEG5000-CREKA is a PEG compound composed of DSPE and the fibrin-targeting peptide (CREKA). The CREKA peptide is utilized for targeting tumor cells and tumor vasculature, exhibiting anti-tumor activity. DSPE-PEG5000-CREKA is applicable in drug delivery systems.</p>Forma y color:Odour SolidMethyl (5α,7α)-7-hydroxy-3-oxocholan-24-oate
CAS:<p>Compound 7a, Methyl (5α,7α)-7-hydroxy-3-oxocholan-24-oate, is a metabolite of bile acid.</p>Fórmula:C25H40O4Forma y color:SolidPeso molecular:404.58IDO1-IN-12
CAS:<p>IDO1-IN-12 is a potent and orally available IDO1 inhibitor.</p>Fórmula:C21H19F3N2O2Forma y color:SolidPeso molecular:388.39BPP
CAS:<p>BPP is a fluorescent microviscosity probe used to image natural HOBr in living cells and zebrafish.</p>Fórmula:C13H13NSForma y color:SolidPeso molecular:215.31Yokonoside
CAS:<p>Yokonoside is a biochemical.</p>Fórmula:C20H21NO11Forma y color:SolidPeso molecular:451.384sn-Glycerol 3-phosphate lithium
<p>Lithium sn-glycerol 3-phosphate made by converting dihydroxyacetone phosphate via NADH from glycolysis.</p>Forma y color:SolidPromothiocin A
CAS:<p>Promothiocin A is an antibiotic.</p>Fórmula:C36H37N11O8S2Pureza:98%Forma y color:SolidPeso molecular:815.88MPC-IN-1
<p>MPC-IN-1 (compound 4i), a derivative of UK-5099, is a cyanocinnamate-based inhibitor of the mitochondrial pyruvate transporter (MPC). This compound selectively fosters the development of hair follicle stem cells while not impacting normal cells. It enhances cellular lactate production and has shown significant hair growth promotion in mice, suggesting its potential use in combating hair loss.</p>Fórmula:C18H13N3O2Forma y color:SolidPeso molecular:303.31Prunetin 5-O-β-D-glucopyranoside
CAS:<p>Prunetin 5-O-β-D-glucopyranoside, an isoflavone obtained from Potentilla astracanica extracts, is a potent uncompetitive inhibitor of α-glucosidase (IC 50 = 56.</p>Fórmula:C22H22O10Forma y color:SolidPeso molecular:446.408Fructosyl-lysine dihydrochloride
CAS:<p>Fructoselysine dihydrochloride, a Maillard reaction product and precursor to diabetes marker glucosepane.</p>Fórmula:C12H26Cl2N2O7Forma y color:SolidPeso molecular:381.25L-Mevalonic acid
CAS:<p>L-Mevalonic acid, a cholesterol precursor, is studied in autoimmune, atherosclerosis, and Alzheimer's research.</p>Fórmula:C6H12O4Pureza:98%Forma y color:SolidPeso molecular:148.16Aculene A
CAS:<p>Aculene A is a unique type of norsesquiterpene from Aspergillus aculeatus [1] .</p>Fórmula:C19H25NO3Forma y color:SolidPeso molecular:315.41HIV-IN-9
<p>HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.</p>Forma y color:Odour SolidGlucose 1-dehydrogenase
CAS:<p>Glucose 1-dehydrogenase, an enzyme, transforms glucose and NAD(P) into NAD(P)H and gluconic acid.</p>Forma y color:Solidtetranor-PGEM
CAS:<p>Tetranor-PGEM, the primary urinary byproduct of PGE1 and PGE2, marks PGE2 production; humans excrete 7-40 μg daily.</p>Fórmula:C16H24O7Forma y color:SolidPeso molecular:328.361D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine
CAS:<p>D-Ribofuranose 1-phosphate is used to synthesize 5-fluorouracil via uridine phosphorylase.</p>Fórmula:C11H24NO8PForma y color:SolidPeso molecular:329.28PDE11A4-IN-1
<p>PDE11A4-IN-1 (compound 23b) is a potent, selective inhibitor of PDE11A4, demonstrating an IC50 of 12 nM and exhibiting high selectivity against PDE1, PDE2,</p>Forma y color:Odour SolidAcetoacetyl coenzyme A sodium
CAS:<p>Acetoacetyl-CoA sodium is a key metabolite, with a Km of 1.10 mM at pH 7.5, used in PTB and PHB synthesis.</p>Fórmula:C25H37N7Na3O18P3SForma y color:SolidPeso molecular:917.55ecMetAP-IN-1
CAS:<p>ecMetAP-IN-1 可用作 QSAR 模型，以使用多元线性回归研究蛋氨酸氨基肽酶抑制剂作为抗癌剂。</p>Fórmula:C13H11N3Pureza:99.34%Forma y color:SolidPeso molecular:209.25Oleic Acid-2,6-diisopropylanilide
CAS:<p>Oleic acid-2,6-diisopropylanilide: ACAT inhibitor, IC50 7 nM; lowers LDL & raises HDL in high-fat fed rabbits/rats at 0.05%.</p>Fórmula:C30H51NOForma y color:SolidPeso molecular:441.744DSPE-PEG2000-Azide ammonium
CAS:<p>DSPE-PEG2000-Azide ammonium is a lipid-based azide compound used in forming micelles for nanoparticle drug delivery. It serves as a click chemistry reagent and includes an azide group that reacts with molecules containing an alkyne group through a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc). Additionally, it can engage in a strain-promoted azide-alkyne cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.</p>Forma y color:Solid
