Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(177 productos)
- Caseína quinasa(130 productos)
- DHFR(32 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(267 productos)
- FAAH(63 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(32 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(53 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(32 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(96 productos)
- Lípido(59 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8595 productos de "Metabolismo"
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FASN-IN-4 tosylate
CAS:<p>FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.</p>Fórmula:C33H35N3O7S2Forma y color:SolidPeso molecular:649.78Cholesteryl Linolenate
CAS:<p>Cholesteryl Linolenate is a human endogenous metabolite.</p>Fórmula:C45H74O2Pureza:98%Forma y color:White SolidPeso molecular:647.07Enniatin A
CAS:<p>Enniatin A, a Fusarium toxin, blocks rat liver ACAT with 22 μM IC50.</p>Fórmula:C36H63N3O9Pureza:98%Forma y color:SolidPeso molecular:681.9LKY-047
CAS:<p>LKY-047 is a Decursin derivative, selectively inhibits CYP2J2 with IC50 of 1.7 μM, not affecting other human P450s.</p>Fórmula:C23H19NO7Forma y color:SolidPeso molecular:421.405LVGRQLEEFL (mouse) (TFA)
<p>G* peptide, also known as LVGRQLEEFL (mouse) TFA, is a segment corresponding to amino acids 113 to 122 ([113,122] apoJ) of apolipoprotein J.</p>Forma y color:Odour Solid4β-hydroxy Cholesterol
CAS:<p>4β-hydroxy Cholesterol is a useful organic compound for research related to life sciences. The catalog number is T21530 and the CAS number is 17320-10-4.</p>Forma y color:SolidPeso molecular:402.6536,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone
CAS:<p>Compound 1, 6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone, is an anthraquinone α-glucosidase inhibitor with an IC50 of 185 μM, and it can be isolated</p>Fórmula:C18H16O7Pureza:98%Forma y color:SolidPeso molecular:344.32SHP2-IN-36
<p>SHP2-IN-36 (Compound B8) is an allosteric inhibitor of SHP2 with an IC50 of 9.0 nM, and it exhibits an IC50 of 40 nM against p-ERK. Moreover, SHP2-IN-36 demonstrates significant antitumor activity in the KYSE520 xenograft mouse model and is applicable for research in the field of antitumor studies.</p>Forma y color:Odour SolidALR2-IN-1
CAS:<p>ALR2-IN-1: potent, selective inhibitor of ALR2 (IC50=1.42 μM), antiglycemic, antioxidant; for diabetes research.</p>Fórmula:C16H17N3O2SPureza:98.79%Forma y color:SoildPeso molecular:315.39Zymostenol
CAS:<p>Zymostenol (5a-Cholest-8-en-3b-ol) is a RORγ agonist with an EC50 of 1 μM.Zymostenol is a late stage precursor of cholesterol biosynthesis.</p>Fórmula:C27H46OPureza:98%Forma y color:SolidPeso molecular:386.65(Rac)-5-Keto Fluvastatin
CAS:<p>(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) is an impurity of Fluvastatin which is an inhibitor of HMG-CoA reductase.</p>Fórmula:C24H24FNO4Pureza:95.04%Forma y color:SolidPeso molecular:409.45Asundexian
CAS:<p>Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa,</p>Fórmula:C26H21ClF4N6O4Pureza:99.89% - 99.90%Forma y color:SolidPeso molecular:592.93Mycophenolic acid-β-D-glucuronide
CAS:<p>Mycophenolic acid glucuronide is the glucuronide metabolite of mycophenolic acid in human plasma.</p>Fórmula:C23H28O12Pureza:98.29%Forma y color:SolidPeso molecular:496.46Bacterial α-Amylase
CAS:<p>Bacterial α-Amylase is an enzyme that catalyzes the hydrolysis reaction of starch into smaller sugar molecules such as maltose and glucose.</p>Forma y color:SolidLDHA-IN-3
CAS:<p>LDHA-IN-3 is a potent selenobenzene-based LDHA inhibitor with a 145.2 nM IC50, useful in cancer research.</p>Fórmula:C13H9F3SePureza:99.71%Forma y color:SolidPeso molecular:301.17N-acetyl Leukotriene E4
CAS:<p>N-acetyl Leukotriene E4 is an endogenous metabolite of Leukotriene E4, less active than Leukotriene E4, causing constriction of the airways.</p>Fórmula:C25H39NO6SForma y color:SolidPeso molecular:481.65ω-Muricholic Acid
CAS:<p>ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid.</p>Fórmula:C24H40O5Forma y color:SolidPeso molecular:408.57NLG802
CAS:<p>NLG802 is a prodrug of indoximod, an orally active indoleamine 2,3-dioxygenase (IDO) inhibitor.</p>Fórmula:C20H30ClN3O3Pureza:99.61%Forma y color:SolidPeso molecular:395.92Sulotroban potassium
<p>Sulotroban potassium is a small molecule thromboxane A2 receptor (TXA2R) antagonist that can be used to study myocardial infarction and thrombosis.</p>Fórmula:C16H16KNO5SPureza:98.02%Forma y color:SoildPeso molecular:373.46Ser-Ala-alloresact acetate
<p>Ser-Ala-alloresact acetate is a sperm-activating peptide (SAP) that is released by marine invertebrate eggs and plays an important role in fertilization.</p>Fórmula:C44H75N13O16S2Pureza:99.73%Forma y color:SolidPeso molecular:1106.28Estrone 3-glucuronide
CAS:<p>Deuterium-labeled Estrone 3-glucuronide is a key urinary marker for predicting fertility.</p>Fórmula:C24H30O8Forma y color:SolidPeso molecular:446.49Erythronic acid potassium
<p>Potassium erythronate is an intrinsic carbohydrate metabolite utilized in researching metabolic diseases.</p>Fórmula:C4H7KO5Pureza:98%Forma y color:SolidPeso molecular:173.99305PROTAC CYP1B1 degrader-2
CAS:<p>PROTAC CYP1B1 degrader-2 (compound PV2), a VHL (von Hippel - Landau) E3 ligase-based degrader of CYP1B1, exhibits a DC50 of 1.0 nM after 24 hours in A549/Taxol cells. Furthermore, it effectively inhibits the growth, migration, and invasion of A549/Taxol cells.</p>Fórmula:C49H56ClN7O5S3Forma y color:SolidPeso molecular:954.66Glycerol-3-phosphate oxidase
CAS:<p>Glycerol-3-phosphate oxidase, from E. coli, is crucial in glycerol metabolism and phospholipid formation, producing electrons via oxidation.</p>Forma y color:SolidCasein kinase 1δ-IN-15
CAS:<p>Casein kinase 1δ-IN-15, an inhibitor for casein kinase 1 (CK1δ), exhibits an IC50 of 0.045 μM [1].</p>Fórmula:C19H17FN6OForma y color:SolidPeso molecular:364.38MTHFD2-IN-4 sodium
<p>MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].</p>Fórmula:C26H21F6N2NaO5Forma y color:SolidPeso molecular:578.44ω-Conotoxin CVIF
<p>ω-Conotoxin CVIF is a selective inhibitor of Ca v 2.2 channels, demonstrating an IC50 value of 34.3 nM in isolated rat DRG neurons.</p>Fórmula:C101H170N40O33S6Pureza:98%Forma y color:SolidPeso molecular:2665.07γ-Acetylenic GABA hydrochloride
CAS:<p>γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.</p>Fórmula:C6H10ClNO2Pureza:99.28% - 99.64%Forma y color:SolidPeso molecular:163.6α-Glucosidase-IN-40
<p>α-Glucosidase-IN-40 (compound 5) serves as a noncompetitive inhibitor of the α-glucosidase enzyme, exhibiting an inhibitory concentration (IC50) of 24.62 μM [1</p>Pureza:98%Forma y color:Odour Solid28-Epirapamycin
CAS:<p>28-Epirapamycin, an impurity of Rapamycin, serves as a potent and specific mTOR inhibitor, exhibiting an IC50 value of 0.1 nM in HEK293 cells [1].</p>Fórmula:C51H79NO13Forma y color:SolidPeso molecular:914.17Hydroxypyruvic acid
CAS:<p>Hydroxypyruvic acid: a metabolic intermediate for glycine, serine, threonine; used by serine-pyruvate aminotransferase, glyoxylate reductase.</p>Fórmula:C3H4O4Pureza:98%Forma y color:SolidPeso molecular:104.06NAMPT degrader-3
<p>NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism.</p>Fórmula:C56H74N8O7SPureza:98%Forma y color:SolidPeso molecular:1003.3H-Ile-Pro-Pro-OH hydrochloride
CAS:<p>H-Ile-Pro-Pro-OH HCl, milk peptide, blocks ACE with 5 μM IC50. Antihypertensive.</p>Fórmula:C16H28ClN3O4Forma y color:SolidPeso molecular:361.86α-Glucosidase-IN-54
CAS:<p>α-Glucosidase-IN-54 (compound 2) functions as an α-glucosidase inhibitor, exhibiting an IC 50 value of 0.011 mM, and is derived from Syzygium jambos (L.). This compound is employed in diabetes research [1].</p>Fórmula:C24H36O3Forma y color:SolidPeso molecular:372.54FABP4-IN-4
<p>FABP4-IN-4 (Compound 30) is an orally effective inhibitor of FABP, with an IC50 value of 1.18 μM against FABP1. In a mouse model of diet-induced obesity, FABP4-IN-4 improves glucose tolerance, reduces levels of blood sugar, lipids, and liver inflammation markers, alleviates hepatic steatosis, and exhibits anti-inflammatory activity.</p>Forma y color:Odour SolidFumiquinazoline D
CAS:<p>Fumiquinazoline D, from A. fumigatus, inhibits Gram-positive/negative bacteria (MIC 8-16 μg/ml) and F. solani, C. albicans (MIC 32, 64 μg/ml).</p>Fórmula:C24H21N5O4Forma y color:SolidPeso molecular:443.463BSO-07
<p>BSO-07 is a ROS/JNK activator that exhibits potent anti-cancer properties, demonstrated by an IC50 of 24.81 μM in human breast cancer (BC) cells. The mechanism of action for BSO-07 involves JNK activation and the promotion of increased ROS levels, which lead to the induction of apoptosis (Apoptosis) and tumorigenic apoptosis. This includes enhanced expression of apoptosis-related proteins such as PARP, Bax, phosphorylated p53, ATF4, and CHOP, along with a reduction in the levels of anti-apoptotic proteins (e.g., Bcl-2, Bcl-xL, and Survivin). BSO-07 holds promise for research in the field of breast cancer.</p>Forma y color:Odour SolidhBChE-IN-3
<p>hBChE-IN-3 (compound 30) serves as both an activator of carbonic anhydrase (CA) and an inhibitor of cholinesterase (ChE), exhibiting IC50 values of 7.4 nM for AchE and 1.9 nM for BchE. This compound is utilized in the research of neurodegenerative and psychiatric disorders.</p>Forma y color:Odour SolidCAIX/CAXII-IN-3
<p>CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.</p>Forma y color:Odour Solidβ-Glucosidase
CAS:<p>β-Glucosidase is a glucoside bond hydrolase involved in glucose metabolism and can be used to study diseases caused by abnormal glucose metabolism.</p>Fórmula:C24H44O12Forma y color:SolidPeso molecular:524.6α-Amylase-IN-11
<p>α-Amylase-IN-11 (compound C5f) is an α-amylase inhibitor with an IC50 of 0.56 μM, effective in reducing glucose levels in vivo. Additionally, it exhibits moderate inhibitory activity against α-glucosidase with an IC50 of 11.03 μM. In mouse models, α-Amylase-IN-11 significantly decreases glucose concentrations, indicating its potential for diabetes research.</p>Fórmula:C22H18N4OSForma y color:SolidPeso molecular:386.47L-Isoleucyl-L-arginine
CAS:<p>L-Isoleucyl-L-arginine, a dipeptide composed of L-isoleucine and L-arginine, acts as a potent angiotensin-converting enzyme (ACE) inhibitor and is utilized in</p>Fórmula:C12H25N5O3Pureza:98%Forma y color:SolidPeso molecular:287.36Doxorubicinol hydrochloride
CAS:<p>Doxorubicinol hydrochloride, also known as 13-Dihydroadriamycin hydrochloride, is a secondary alcohol metabolite derived from Doxorubicin.</p>Fórmula:C27H32ClNO11Forma y color:SolidPeso molecular:582.0VM4-037
CAS:<p>VM4-037 is a PET imaging agent used for carbonic anhydrase IX.</p>Fórmula:C26H29FN6O7S2Forma y color:SolidPeso molecular:620.67Nedosiran sodium
CAS:<p>Nedosiran sodium, a GalNAc-dsRNA conjugate, is engineered to suppress the synthesis of the hepatic lactate dehydrogenase (LDH) enzyme.</p>Forma y color:SolidXanthine oxidase-IN-16
<p>Xanthine oxidase-IN-16 is an effective orally active inhibitor of xanthine oxidase (XO), demonstrating significant therapeutic efficacy in rats with hyperuricemia and an IC50 of 102 nM.</p>Forma y color:Odour Solid(24S)-MC 976
CAS:<p>(24S)-MC 976 is a derivative of Vitamin D3.</p>Fórmula:C27H42O3Pureza:98%Forma y color:SolidPeso molecular:414.62WXC-25
<p>WXC-25 is an α-glucosidase inhibitor with an IC50 value of 2.02 μM.</p>Forma y color:Odour SolidBTT-266
CAS:<p>BTT-266 is a blocker of voltage-gated calcium channel for pain management.</p>Fórmula:C34H28N4O4Pureza:98.34%Forma y color:SolidPeso molecular:556.61SAICAR
CAS:<p>SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner (EC50: 0.3 mM).</p>Fórmula:C13H19N4O12PPureza:98%Forma y color:SolidPeso molecular:454.28
