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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

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Se han encontrado 8597 productos de "Metabolismo"

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  • β-Glucosidase

    CAS:
    <p>β-Glucosidase is a glucoside bond hydrolase involved in glucose metabolism and can be used to study diseases caused by abnormal glucose metabolism.</p>
    Fórmula:C24H44O12
    Forma y color:Solid
    Peso molecular:524.6
  • Ro 61-1448

    CAS:
    <p>Ro 61-1448 is a metabolite of tolcapone, a catechol-O-methyltransferase inhibitor.</p>
    Fórmula:C20H19NO11
    Pureza:98%
    Forma y color:Solid
    Peso molecular:449.36
  • IOX2-NH2-1

    CAS:
    <p>IOX2-NH2-1 inhibits E. coli EGLN-3 (prolyl hydroxylase) with an IC50 of 0.02–1 μM.</p>
    Fórmula:C19H17N3O5
    Pureza:98.77% - 99.91%
    Forma y color:Soild
    Peso molecular:367.36
  • Febuxostat impurity 6

    CAS:
    <p>Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>
    Fórmula:C18H22N2O4S
    Forma y color:Solid
    Peso molecular:362.44
  • Thymidine 5′-diphosphate

    CAS:
    <p>Thymidine 5′-diphosphate (dTDP), a crucial product of pyrimidine synthesis in organisms, is synthesized through the thymidylate kinase (TMPK)-catalyzed</p>
    Fórmula:C10H16N2O11P2
    Forma y color:Solid
    Peso molecular:402.19
  • Cholesterol glucuronide

    CAS:
    <p>Cholesterol glucuronide is an endogenous metabolite of lipid generated by UDP glucuonyltransferase in the liver.</p>
    Fórmula:C33H54O7
    Pureza:98%
    Forma y color:Solid
    Peso molecular:562.78
  • ALR2-IN-1

    CAS:
    <p>ALR2-IN-1: potent, selective inhibitor of ALR2 (IC50=1.42 μM), antiglycemic, antioxidant; for diabetes research.</p>
    Fórmula:C16H17N3O2S
    Pureza:98.79%
    Forma y color:Soild
    Peso molecular:315.39
  • 2-Nitrophenyl a-D-glucopyranoside

    CAS:
    <p>2-Nitrophenyl a-D-glucopyranoside is a substrate of β-glucosidase [1] .</p>
    Fórmula:C12H15NO8
    Forma y color:Solid
    Peso molecular:301.25
  • WXC-25


    <p>WXC-25 is an α-glucosidase inhibitor with an IC50 value of 2.02 μM.</p>
    Forma y color:Odour Solid
  • NLG802

    CAS:
    <p>NLG802 is a prodrug of indoximod, an orally active indoleamine 2,3-dioxygenase (IDO) inhibitor.</p>
    Fórmula:C20H30ClN3O3
    Pureza:99.61%
    Forma y color:Solid
    Peso molecular:395.92
  • GS-704277

    CAS:
    <p>GS-704277, a Remdesivir metabolite, shows potent in vitro effects against COVID-19.</p>
    Fórmula:C15H19N6O8P
    Forma y color:Solid
    Peso molecular:442.325
  • (S)-O-Desmethyl Venlafaxine N-Oxide

    CAS:
    <p>(S)-O-Desmethyl Venlafaxine N-Oxide is the N-oxide metabolite of Venlafaxine, an SNRI antidepressant.</p>
    Fórmula:C16H25NO3
    Forma y color:Solid
    Peso molecular:279.37
  • FXR antagonist 2

    CAS:
    <p>Compound A-26, a diarylamide FXR blocker, may aid hyperlipidemia and diabetes type 2 research.</p>
    Fórmula:C22H26Cl2N2O2
    Forma y color:Solid
    Peso molecular:421.36
  • 1-Naphthyl 3,5-dinitrobenzoate

    CAS:
    <p>1-Naphthyl 3,5-dinitrobenzoate (JMC-4) is an inhibitor of 5-LOX can be used in studies about inflammatory therapy.</p>
    Fórmula:C17H10N2O6
    Pureza:99.79%
    Forma y color:Solid
    Peso molecular:338.27
  • γ-glutamyltransferase

    CAS:
    <p>γ-glutamyltransferase (GGT) is an enzyme located on the outer surface of the cell membrane. It maintains physiological concentrations of intracellular glutathione and cellular defense against oxidative stress by cleaving extracellular glutathione and increasing the availability of amino acids. γ-glutamyltransferase can be utilized as a biomaterial or organic compound in life science-related research.</p>
    Forma y color:Solid
  • 2-Hydroxy atorvastatin lactone

    CAS:
    <p>2-Hydroxy atorvastatin lactone, a metabolite of Atorvastatin, is an orally active HMG-CoA reductase inhibitor that efficiently reduces blood lipids [1][2].</p>
    Fórmula:C33H33FN2O5
    Forma y color:Solid
    Peso molecular:556.62
  • SX29


    <p>SX29 is a non-competitive α-glucosidase inhibitor with oral activity, exhibiting an IC50 of 2.12 μM. It possesses hypoglycemic properties; oral administration of SX29 reduces blood glucose levels and enhances glucose tolerance in diabetic mice.</p>
    Forma y color:Odour Solid
  • α-Glucosidase-IN-74


    <p>α-Glucosidase-IN-74, a nicotinamide-thiazole derivative, functions as an α-glucosidase (α-glucosidase) inhibitor. It demonstrates antidiabetic activity by reducing blood glucose and triglyceride levels in Streptozotocin-induced diabetic animals.</p>
    Forma y color:Odour Solid
  • Isomer-Turosteride


    <p>Isomer-Turosteride, a novel 5α-reductase inhibitor, reduces prostate DHT and has anticancer properties without raising T levels.</p>
    Fórmula:C27H45N3O3
    Pureza:98.94%
    Forma y color:Solid
    Peso molecular:459.67
  • Zaragozic acid D

    CAS:
    <p>Zaragozic acid D inhibits squalene synthase and ras farnesyl-protein transferase isolated from the keratinophilic fungus Amauroascus niger.</p>
    Fórmula:C34H46O14
    Forma y color:Solid
    Peso molecular:678.72
  • FUT8-IN-1


    <p>FUT8-IN-1 (Compound 37) is an inhibitor of α-1,6-fucosyltransferase (FUT8), with a dissociation constant (KD) of 49 nM and an IC50 around 50 µM. In the presence of FUT8, FUT8-IN-1 forms a highly active naphthoquinone imine intermediate, thereby inhibiting FUT8's enzymatic activity.</p>
    Fórmula:C23H25ClN2O
    Forma y color:Solid
    Peso molecular:380.91
  • NIM811

    CAS:
    <p>NIM811 is an orally bioavailable dual inhibitor of mitochondrial permeability transition and cyclophilin.</p>
    Fórmula:C62H111N11O12
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1202.635
  • Prolylglutamic acid

    CAS:
    <p>Prolylglutamic acid (H-Pro-Glu-OH) is a proline-glutamic acid dipeptide and endogenous metabolite, targeting the LipY lipase of pathogenic mycobacteria.</p>
    Fórmula:C10H16N2O5
    Forma y color:Solid
    Peso molecular:244.24
  • Phenacaine

    CAS:
    <p>Phenacaine, also known as Holocaine, is a local anesthetic that blocks certain Ca 2+ enzymes in red blood cells, brain, and heart.</p>
    Fórmula:C18H22N2O2
    Forma y color:Solid
    Peso molecular:298.38
  • Carbolactone

    CAS:
    <p>Carbolactone is a biologically active metabolite from fungi [1] .</p>
    Fórmula:C24H36O3
    Forma y color:Solid
    Peso molecular:372.54
  • Xanthine oxidase-IN-13


    <p>Xanthine oxidase-IN-13 (Compound 10) is a selective inhibitor of xanthine oxidase, with an IC50 of 149.56 μM for bovine xanthine oxidase. It is utilized in the study of inflammatory arthritis.</p>
    Fórmula:C14H13NO
    Peso molecular:211.09971
  • PK-10


    <p>PK-10, when combined with Fluconazole, exhibits potent synergistic antifungal activity against multiple Fluconazole-resistant Candida albicans strains.</p>
    Fórmula:C35H36F3N5O
    Forma y color:Solid
    Peso molecular:599.69
  • Leucylproline

    CAS:
    <p>Leucylproline is a peptide that proteolytic breakdown product by larger proteins.</p>
    Fórmula:C11H20N2O3
    Forma y color:Solid
    Peso molecular:228.29
  • 8-Demethyl Ivabradine

    CAS:
    <p>8-Demethyl Ivabradine, a metabolite of Ivabradine, is an oral HCN channel blocker.</p>
    Fórmula:C26H34N2O5
    Forma y color:Solid
    Peso molecular:454.567
  • 11,12-DiHETrE

    CAS:
    <p>11,12-DiHETrE: Endogenous P450 eicosanoid, used in preterm labor study and NAFL/NASH differentiation.</p>
    Fórmula:C20H34O4
    Forma y color:Solid
    Peso molecular:338.48
  • Pectin

    CAS:
    <p>Pectin, a plant cell wall derived heteropolysaccharide, forms nanoparticles for delivery and acts as an antimicrobial adsorbent.</p>
    Forma y color:Solid
  • Tacalcitol monohydrate

    CAS:
    <p>Tacalcitol monohydrate(Curatoderm monohydrate), a vitamin D3 analog that promotes bone development by regulating calcium ions, can be used to study psoriasis.</p>
    Fórmula:C27H46O4
    Pureza:99.93%
    Forma y color:Solid
    Peso molecular:434.65
  • 1-epi-Regadenoson

    CAS:
    <p>1-epi-Regadenoson is an α-isomer impurity of Regadenoson, a highly selective adenosine A2A receptor agonist [1].</p>
    Fórmula:C15H18N8O5
    Forma y color:Solid
    Peso molecular:390.35
  • Transketolase-IN-5


    <p>Transketolase-IN-5 (compound 6ba) is an inhibitor of transketolase. It exhibits herbicidal activity against Amaranthus retroflexus, Setaria viridis, and Digitaria sanguinalis.</p>
    Fórmula:C20H24ClN5O
    Peso molecular:385.16694
  • DSPE-PEG5000-SP94


    <p>DSPE-PEG5000-SP94 is a PEGylated compound composed of DSPE and the cell-penetrating peptide (SP94). SP94 demonstrates specific binding affinity to hepatocellular carcinoma (HCC) cells.</p>
    Forma y color:Odour Solid
  • SF2312 ammonium


    <p>SF2312 ammonium is the ammonium salt of SF2312, a phosphonate antibiotic and enolase inhibitor derived from the actinomycete Micromonospora and active under</p>
    Fórmula:C4H11N2O6P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:214.11
  • Acremonidin A

    CAS:
    <p>Acremonidin A, from Purpureocillium lilacinum, is a strong CaM inhibitor binding to hCaM M124C-mBBr with a Kd of 19.40 nM.</p>
    Fórmula:C33H26O12
    Forma y color:Solid
    Peso molecular:614.55
  • Neo-inositol

    CAS:
    <p>Neo-Inositol, a stable, polar compound, is a rare natural inositol stereoisomer.</p>
    Fórmula:C6H12O6
    Forma y color:Solid
    Peso molecular:180.16
  • 5′-Nucleotidase

    CAS:
    <p>5′-Nucleotidase (CD73), an ectoenzyme and intrinsic membrane glycoprotein, catalyzes the hydrolysis of 5-nucleotides into their corresponding nucleosides [1].</p>
    Forma y color:Solid
  • Hexokinase II VDAC binding domain peptide, cell-permeable


    <p>HexokinaseIIVDACbinding domain peptide (Hxk2VBD peptide) is a cell-permeable peptide derived from the hexokinase II VDAC binding domain. This peptide inhibits the mitochondrial localization of hexokinase 2 (HXK2) and also suppresses neurotrophic factor-induced axon growth.</p>
    Fórmula:C188H291N53O40S2
    Peso molecular:3995.18073
  • Anti-Cancer Metabolism Compound Library


    <p>A unique collection of 1268 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS</p>
    Forma y color:Odour Solid
  • S32826

    CAS:
    <p>S32826, a potent autotaxin inhibitor with an IC50 of 8.8 nM, blocks LPA release and targets α, β, γ isoforms.</p>
    Fórmula:C21H36NO4P
    Forma y color:Solid
    Peso molecular:397.496
  • α-Amylase/α-Glucosidase-IN-15


    <p>α-Amylase/α-Glucosidase-IN-15 (compound 6C) is an orally active inhibitor of α-glucosidase (α-Glucosidase) and α-amylase (α-amylase), with IC50 values of 21 μM and 61 μM, respectively.</p>
    Fórmula:C26H24N4O3S
    Peso molecular:472.15691
  • LTA4H-IN-4


    <p>LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.</p>
  • GLUT1-IN-1


    <p>GLUT1-IN-1 inhibits GLUT1; cytotoxic to HeLa, A549, HepG2 (IC50: 5.49, 11.14, 8.73 μM); potential in PDT and cancer research.</p>
    Fórmula:C25H31BF2I2N6O7
    Forma y color:Solid
    Peso molecular:830.17
  • Galactose oxidase

    CAS:
    <p>GOase, a type II copper enzyme from fungus, oxidizes alcohols to aldehydes and reduces O2 to H2O2.</p>
    Forma y color:Solid
  • 1-Palmitoyl Lysophosphatidic Acid

    CAS:
    <p>1-Palmitoyl Lysophosphatidic Acid boosts antibiotics against P. aeruginosa by binding Ca2+ and Mg2+.</p>
    Fórmula:C19H39O7P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:410.48
  • α-Glucosidase-IN-65


    <p>α-Glucosidase-IN-65 (compound 5) is a Schiff base derivative of 3,4-dihydroxyphenylacetic acid. It acts as a potent α-glucosidase inhibitor with an IC50 of 12.84 μM.</p>
    Fórmula:C15H14N2O6
    Peso molecular:318.08519
  • Hexaglutamate folate

    CAS:
    <p>Hexaglutamate folate, a natural folic acid form, requires deconjugation for absorption; its deficiency can lead to anemia and numerous chronic diseases.</p>
    Fórmula:C44H54N12O21
    Forma y color:Solid
    Peso molecular:1086.97
  • GZ22-4


    <p>GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.</p>
    Fórmula:C88H126F3N6NaO24S4
    Peso molecular:1858.75561