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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8595 productos de "Metabolismo"

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  • Cellulose

    CAS:
    <p>Cellulose, an excipient, aids stability, solubility, and processing of drugs and affects their ADME.</p>
    Fórmula:C12H22O11
    Forma y color:Solid
    Peso molecular:342.297
  • Cryptosporioptide A

    CAS:
    <p>Cryptosporioptide A (Compound 3), a protein tyrosine phosphatase inhibitor, originates from the insect-parasitic fungus Cordyceps gracilioides.</p>
    Fórmula:C18H17NO10
    Pureza:98%
    Forma y color:Solid
    Peso molecular:407.33
  • 3α-Akebonoic Acid

    CAS:
    <p>3α-Akebonoic acid is a natural product isolated from Holboellia coriacea Diels with antitumor activity.</p>
    Fórmula:C29H44O3
    Forma y color:Solid
    Peso molecular:440.67
  • (S)-3,4-Dihydroxybutyric acid

    CAS:
    <p>(S)-3,4-Dihydroxybutyric acid is a human urinary metabolite.</p>
    Fórmula:C4H8O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:120.1
  • VDR agonist 3


    <p>VDR agonist 3 (Compound E15) is a potent activator of the vitamin D receptor (VDR). It effectively inhibits the activation of hepatic stellate cells (HSC) via VDR. In a model of liver fibrosis induced by CCl4 in mice, VDR agonist 3 significantly alleviates liver fibrosis without causing hypercalcemia.</p>
    Fórmula:C24H36O7
    Forma y color:Solid
    Peso molecular:436.538
  • CP-610431

    CAS:
    <p>CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.</p>
    Fórmula:C30H37N3O2
    Forma y color:Solid
    Peso molecular:471.645
  • Berninamycin D

    CAS:
    <p>Berninamycin D, a cyclic peptide derived from Streptomyces bernensis through fermentation, is recognized as a fungal metabolite [1].</p>
    Fórmula:C45H45N13O13S
    Forma y color:Solid
    Peso molecular:1007.98
  • (±)-Hexanoylcarnitine chloride

    CAS:
    <p>(±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into small compounds that can be utilized by the body.</p>
    Fórmula:C13H26ClNO4
    Pureza:99.45%
    Forma y color:Solid
    Peso molecular:295.8
  • Histone acetyltransferase p300 Inhibitor 4c

    CAS:
    <p>2-Amino-4-(4-chlorophenyl)thiazole blocks hCA I/II, AChE, BChE with Ki: ~0.008, 0.124, 0.129, 0.083 µM.</p>
    Fórmula:C9H7ClN2S
    Pureza:99.76%
    Forma y color:Solid
    Peso molecular:210.68
  • Hydroxycotinine

    CAS:
    <p>Hydroxycotinine is the main nicotine metabolite detected in smokers' urine.</p>
    Fórmula:C10H12N2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:192.218
  • Kallikrein

    CAS:
    <p>Kallikrein is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides , respectively [1] .</p>
    Forma y color:Solid
  • Captopril EP Impurity B

    CAS:
    <p>Captopril EP Impurity B, an antihypertensive thiol ACE inhibitor with IC50 of 0.025 μM.</p>
    Fórmula:C9H14BrNO3
    Forma y color:Solid
    Peso molecular:264.12
  • 15-LOX-1 inhibitor 1

    CAS:
    <p>9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, &amp; cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.</p>
    Fórmula:C22H21ClN2O4
    Forma y color:Solid
    Peso molecular:412.87
  • THX6


    <p>THX6 is an activator of human mitochondrial protease ClpP, with an EC50 of 1.18 μM. It displays cytotoxicity in ONC201-resistant SU-DIPG-VI cells, with an IC50 of 0.13 μM. THX6 inhibits the expression of mitochondria-related proteins (such as parkin, TFAM, NRF1, SDHA), leading to impaired mitochondrial function. Additionally, THX6 affects cell membrane lipid metabolism and exhibits antitumor potential.</p>
    Fórmula:C22H18Cl2N4O2
    Forma y color:Solid
    Peso molecular:441.31
  • cis-Vitamin K1

    CAS:
    <p>Cis-Vitamin K1 is an endogenous metabolite of Vitamin K [1] .</p>
    Fórmula:C31H46O2
    Forma y color:Solid
    Peso molecular:450.70
  • Glutamic acid protease

    CAS:
    <p>Glutamic protease, a proteolytic enzyme characterized by the presence of a glutamic acid residue [1], is exclusive to fungi.</p>
    Forma y color:Solid
  • Andrastin A

    CAS:
    <p>Andrastin A is a useful organic compound for research related to life sciences. The catalog number is T125574 and the CAS number is 174232-42-9.</p>
    Fórmula:C28H38O7
    Forma y color:Solid
    Peso molecular:486.605
  • NU227326

    CAS:
    <p>NU227326 is a PROTAC degrader of indoleamine 2,3-dioxygenase 1 (IDO1) with a DC50 value of 4.5 nM. It effectively degrades IDO1 in U87 and GBM43 cells, with DC50 values of 7.1 nM and 11.8 nM, respectively. NU227326 exhibits favorable pharmacokinetic properties, with a plasma half-life of 5.7 hours and a brain tissue half-life of 11.8 hours. (Pink: ligand for target protein IDO1 ligand-1; Black: linker; Blue: ligand for E3 ligase Cereblon).</p>
    Fórmula:C53H61FN8O7
    Forma y color:Solid
    Peso molecular:941.099
  • L-Lactate dehydrogenase

    CAS:
    <p>L-Lactate dehydrogenase is an enantiospecific redox enzyme reducing pyruvate to L-lactate using NADH.</p>
    Forma y color:Solid
  • CB1151

    CAS:
    <p>CB1151 is a 20-epi analogue of 1,25 dihydroxyvitamin D3 with anti-tumor effects. It inhibits MCF-7 cell growth (IC50: 0.82 nM).</p>
    Fórmula:C28H46O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:446.66
  • 1,2-Dilinoleoyl-sn-glycerol

    CAS:
    <p>1,2-Dilinoleoyl-sn-glycerol, a DAG with two linoleic acids, is in rat liver, spinach membranes, and indicates preeclampsia risk in pregnancy.</p>
    Fórmula:C39H68O5
    Forma y color:Solid
    Peso molecular:616.95
  • ω-Conotoxin FVIA


    <p>ω-Conotoxin FVIA is an inhibitor of N-type Ca²⁺ channels (Caᵥ2.2), shown to alleviate mechanical and thermal pain abnormalities in a rat model of caudal nerve</p>
    Fórmula:C98H164N36O33S6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2566.96
  • Methylcardol triene

    CAS:
    <p>Methylcardol triene, a phenolic compound present in cashew nut shell liquid, demonstrates α-glucosidase inhibition (IC50= 39.6 µM) and exhibits schistosomicidal properties by eliminating 100% of adult S. mansoni worms within 24 hours at 100 and 200 µM concentrations. Moreover, it serves as a precursor for synthesizing mono- and bis-benzoxazines.</p>
    Fórmula:C22H32O2
    Forma y color:Solid
    Peso molecular:328.496
  • Carboxyaminoimidazole ribotide

    CAS:
    <p>CAIR, an E. coli metabolite, helps identify its PurE active site and aids in fungal purine synthesis.</p>
    Fórmula:C9H14N3O9P
    Forma y color:Solid
    Peso molecular:339.2
  • Enpp-1-IN-15

    CAS:
    <p>Compound 88a (Enpp-1-IN-15) is an inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (Enpp-1), exhibiting a Ki value of 0.00586 nM [1].</p>
    Fórmula:C16H20N6O2S
    Forma y color:Solid
    Peso molecular:360.43
  • UDP-sugar pyrophosphorylase (BlUSP)

    CAS:
    <p>BlUSP enzyme turns Glc-1-P into UDP-Glucose, transferring uridyl from UTP and producing PPi.</p>
    Forma y color:Solid
  • Galcuronokinase (AtGalAK)


    <p>AtGalAK, a GHMP kinase, converts d-GalA to GalA-1-P using ATP.</p>
    Forma y color:Solid
  • Biotin-Vitamin B12


    <p>Biotin-Vitamin B12, a biotinylated form, is crucial for brain, nervous system function, and blood formation.</p>
    Fórmula:C73H102CoN16O16PS
    Forma y color:Solid
    Peso molecular:1581.66
  • DSPE-PEG1000-CGKRK


    <p>DSPE-PEG1000-CGKRK is a PEG compound composed of DSPE and the cell-penetrating peptide (CGKRK). It is utilized for drug delivery.</p>
    Forma y color:Odour Solid
  • N4-Acetylcytidine triphosphate

    CAS:
    <p>N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription .</p>
    Fórmula:C11H18N3O15P3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:525.19
  • (S)-Higenamine

    CAS:
    <p>(S)-Higenamine, a benzylisoquinoline precursor, forms from dopamine and 4-HPAA via NCS.</p>
    Fórmula:C16H17NO3
    Forma y color:Solid
    Peso molecular:271.31
  • 6-Azathymine acid

    CAS:
    <p>6-Azathymine is a metabolite of Pymetrozine, an insecticide targeting aphids and whiteflies by disrupting feeding.</p>
    Fórmula:C4H3N3O4
    Forma y color:Solid
    Peso molecular:157.08
  • Lunine

    CAS:
    <p>Lunine is a bioactive chemical.</p>
    Fórmula:C16H17NO4
    Forma y color:Solid
    Peso molecular:287.31
  • L-Pyroglutamic acid β-naphthylamide

    CAS:
    <p>L-Pyroglutamic acid β-naphthylamide (PYR) is a derivative of glutamic acid.</p>
    Fórmula:C15H14N2O2
    Forma y color:Solid
    Peso molecular:254.28
  • Calcium gluconate monohydrate

    CAS:
    <p>Calcium gluconate monohydrate is a useful organic compound for research related to life sciences. The catalog number is T35350 and the CAS number is 66905-23-5.</p>
    Fórmula:C6H16CaO8
    Pureza:98%
    Forma y color:Solid
    Peso molecular:256.264
  • Adenylosuccinic acid tetraammonium


    <p>Adenylosuccinic acid, orally active, is a purine ribonucleotide involved in nucleotide metabolism, may aid in DMD studies.</p>
    Fórmula:C14H30N9O11P
    Forma y color:Solid
    Peso molecular:531.42
  • Hydroxychloroquine Impurity F

    CAS:
    <p>Hydroxychloroquine Impurity F, a byproduct, is an antimalarial that blocks TLR7/9 and inhibits SARS-CoV-2 in vitro.</p>
    Fórmula:C14H15ClN2
    Forma y color:Solid
    Peso molecular:246.74
  • Febuxostat impurity 8

    CAS:
    <p>Febuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>
    Fórmula:C16H17NO4S
    Forma y color:Solid
    Peso molecular:319.38
  • Mersalyl

    CAS:
    <p>Mersalyl is an organic mercurial diuretic.</p>
    Fórmula:C13H16HgNNaO6
    Forma y color:Solid
    Peso molecular:505.854
  • Tetracosanoyl-sulfatide

    CAS:
    <p>C24 3'-sulfo Galactosylceramide is a key myelin sulfatide, high in leukodystrophy patients, non-immunogenic compared to C24:1 variant.</p>
    Fórmula:C48H93NO11S
    Forma y color:Solid
    Peso molecular:892.32
  • Palitantin

    CAS:
    <p>Palitantin is a useful organic compound for research related to life sciences. The catalog number is T125757 and the CAS number is 15265-28-8.</p>
    Fórmula:C14H22O4
    Forma y color:Solid
    Peso molecular:254.326
  • 11β-HSD1-IN-11

    CAS:
    <p>11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13</p>
    Fórmula:C15H11F3O3S
    Pureza:99.61%
    Forma y color:Soild
    Peso molecular:328.31
  • Coenzyme A

    CAS:
    <p>Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.</p>
    Fórmula:C21H36N7O16P3S
    Pureza:93.84%
    Forma y color:Solid
    Peso molecular:767.53
  • N1-Acetylspermine

    CAS:
    <p>N1-Acetylspermine, an endogenous metabolite found in urine, has applications in leukemia research [1] [2].</p>
    Fórmula:C12H28N4O
    Forma y color:Solid
    Peso molecular:244.38
  • 2-(2',3',4'-Trihydroxybutyl)quinoxaline

    CAS:
    <p>2-(2',3',4'-Trihydroxybutyl)quinoxaline is a food metabolite.</p>
    Fórmula:C12H14N2O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:234.25
  • UDP-3-O-acyl-GlcNAc

    CAS:
    <p>UDP-3-O-acyl-GlcNAc is an E. coli metabolite for KDO biosynthesis.</p>
    Fórmula:C31H53N3O19P2
    Forma y color:Solid
    Peso molecular:833.71
  • TSPO/Carbonic Anhydrase Modulator 1


    <p>TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.</p>
    Fórmula:C35H51N3O3
    Forma y color:Solid
    Peso molecular:561.798
  • 5(S)​-​HPETE

    CAS:
    <p>5(S)-HpETE is a PUFA made by 5-LO from arachidonic acid, metabolized into LTA4, a key leukotriene precursor.</p>
    Fórmula:C20H32O4
    Forma y color:Solid
    Peso molecular:336.472
  • Eremofortin A

    CAS:
    <p>Eremofortin A, a metabolite, can be isolated from Penicillium roqueforti cultures [1].</p>
    Fórmula:C17H22O5
    Forma y color:Solid
    Peso molecular:306.35
  • D-Fructose-13C6

    CAS:
    <p>D-Fructose-13C6 can be used as an internal standard for the quantification of D-fructose by GC- or LC-MS.</p>
    Fórmula:C6H12O6
    Pureza:98% - 99.64%
    Forma y color:Solid
    Peso molecular:186.11