
Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(177 productos)
- Caseína quinasa(130 productos)
- DHFR(32 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(267 productos)
- FAAH(63 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(32 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(53 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(32 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(96 productos)
- Lípido(59 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8595 productos de "Metabolismo"
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Cellulose
CAS:<p>Cellulose, an excipient, aids stability, solubility, and processing of drugs and affects their ADME.</p>Fórmula:C12H22O11Forma y color:SolidPeso molecular:342.297Cryptosporioptide A
CAS:<p>Cryptosporioptide A (Compound 3), a protein tyrosine phosphatase inhibitor, originates from the insect-parasitic fungus Cordyceps gracilioides.</p>Fórmula:C18H17NO10Pureza:98%Forma y color:SolidPeso molecular:407.333α-Akebonoic Acid
CAS:<p>3α-Akebonoic acid is a natural product isolated from Holboellia coriacea Diels with antitumor activity.</p>Fórmula:C29H44O3Forma y color:SolidPeso molecular:440.67(S)-3,4-Dihydroxybutyric acid
CAS:<p>(S)-3,4-Dihydroxybutyric acid is a human urinary metabolite.</p>Fórmula:C4H8O4Pureza:98%Forma y color:SolidPeso molecular:120.1VDR agonist 3
<p>VDR agonist 3 (Compound E15) is a potent activator of the vitamin D receptor (VDR). It effectively inhibits the activation of hepatic stellate cells (HSC) via VDR. In a model of liver fibrosis induced by CCl4 in mice, VDR agonist 3 significantly alleviates liver fibrosis without causing hypercalcemia.</p>Fórmula:C24H36O7Forma y color:SolidPeso molecular:436.538CP-610431
CAS:<p>CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.</p>Fórmula:C30H37N3O2Forma y color:SolidPeso molecular:471.645Berninamycin D
CAS:<p>Berninamycin D, a cyclic peptide derived from Streptomyces bernensis through fermentation, is recognized as a fungal metabolite [1].</p>Fórmula:C45H45N13O13SForma y color:SolidPeso molecular:1007.98(±)-Hexanoylcarnitine chloride
CAS:<p>(±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into small compounds that can be utilized by the body.</p>Fórmula:C13H26ClNO4Pureza:99.45%Forma y color:SolidPeso molecular:295.8Histone acetyltransferase p300 Inhibitor 4c
CAS:<p>2-Amino-4-(4-chlorophenyl)thiazole blocks hCA I/II, AChE, BChE with Ki: ~0.008, 0.124, 0.129, 0.083 µM.</p>Fórmula:C9H7ClN2SPureza:99.76%Forma y color:SolidPeso molecular:210.68Hydroxycotinine
CAS:<p>Hydroxycotinine is the main nicotine metabolite detected in smokers' urine.</p>Fórmula:C10H12N2O2Pureza:98%Forma y color:SolidPeso molecular:192.218Kallikrein
CAS:<p>Kallikrein is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides , respectively [1] .</p>Forma y color:SolidCaptopril EP Impurity B
CAS:<p>Captopril EP Impurity B, an antihypertensive thiol ACE inhibitor with IC50 of 0.025 μM.</p>Fórmula:C9H14BrNO3Forma y color:SolidPeso molecular:264.1215-LOX-1 inhibitor 1
CAS:<p>9c(i472) blocks 15-LO-1 (IC50=0.19μM), lowers NF-κB in RAW-Blue cells, & cuts Nos2/lipid peroxidation in RAW 264.7 at 0.2-5μM.</p>Fórmula:C22H21ClN2O4Forma y color:SolidPeso molecular:412.87THX6
<p>THX6 is an activator of human mitochondrial protease ClpP, with an EC50 of 1.18 μM. It displays cytotoxicity in ONC201-resistant SU-DIPG-VI cells, with an IC50 of 0.13 μM. THX6 inhibits the expression of mitochondria-related proteins (such as parkin, TFAM, NRF1, SDHA), leading to impaired mitochondrial function. Additionally, THX6 affects cell membrane lipid metabolism and exhibits antitumor potential.</p>Fórmula:C22H18Cl2N4O2Forma y color:SolidPeso molecular:441.31cis-Vitamin K1
CAS:<p>Cis-Vitamin K1 is an endogenous metabolite of Vitamin K [1] .</p>Fórmula:C31H46O2Forma y color:SolidPeso molecular:450.70Glutamic acid protease
CAS:<p>Glutamic protease, a proteolytic enzyme characterized by the presence of a glutamic acid residue [1], is exclusive to fungi.</p>Forma y color:SolidAndrastin A
CAS:<p>Andrastin A is a useful organic compound for research related to life sciences. The catalog number is T125574 and the CAS number is 174232-42-9.</p>Fórmula:C28H38O7Forma y color:SolidPeso molecular:486.605NU227326
CAS:<p>NU227326 is a PROTAC degrader of indoleamine 2,3-dioxygenase 1 (IDO1) with a DC50 value of 4.5 nM. It effectively degrades IDO1 in U87 and GBM43 cells, with DC50 values of 7.1 nM and 11.8 nM, respectively. NU227326 exhibits favorable pharmacokinetic properties, with a plasma half-life of 5.7 hours and a brain tissue half-life of 11.8 hours. (Pink: ligand for target protein IDO1 ligand-1; Black: linker; Blue: ligand for E3 ligase Cereblon).</p>Fórmula:C53H61FN8O7Forma y color:SolidPeso molecular:941.099L-Lactate dehydrogenase
CAS:<p>L-Lactate dehydrogenase is an enantiospecific redox enzyme reducing pyruvate to L-lactate using NADH.</p>Forma y color:SolidCB1151
CAS:<p>CB1151 is a 20-epi analogue of 1,25 dihydroxyvitamin D3 with anti-tumor effects. It inhibits MCF-7 cell growth (IC50: 0.82 nM).</p>Fórmula:C28H46O4Pureza:98%Forma y color:SolidPeso molecular:446.661,2-Dilinoleoyl-sn-glycerol
CAS:<p>1,2-Dilinoleoyl-sn-glycerol, a DAG with two linoleic acids, is in rat liver, spinach membranes, and indicates preeclampsia risk in pregnancy.</p>Fórmula:C39H68O5Forma y color:SolidPeso molecular:616.95ω-Conotoxin FVIA
<p>ω-Conotoxin FVIA is an inhibitor of N-type Ca²⁺ channels (Caᵥ2.2), shown to alleviate mechanical and thermal pain abnormalities in a rat model of caudal nerve</p>Fórmula:C98H164N36O33S6Pureza:98%Forma y color:SolidPeso molecular:2566.96Methylcardol triene
CAS:<p>Methylcardol triene, a phenolic compound present in cashew nut shell liquid, demonstrates α-glucosidase inhibition (IC50= 39.6 µM) and exhibits schistosomicidal properties by eliminating 100% of adult S. mansoni worms within 24 hours at 100 and 200 µM concentrations. Moreover, it serves as a precursor for synthesizing mono- and bis-benzoxazines.</p>Fórmula:C22H32O2Forma y color:SolidPeso molecular:328.496Carboxyaminoimidazole ribotide
CAS:<p>CAIR, an E. coli metabolite, helps identify its PurE active site and aids in fungal purine synthesis.</p>Fórmula:C9H14N3O9PForma y color:SolidPeso molecular:339.2Enpp-1-IN-15
CAS:<p>Compound 88a (Enpp-1-IN-15) is an inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (Enpp-1), exhibiting a Ki value of 0.00586 nM [1].</p>Fórmula:C16H20N6O2SForma y color:SolidPeso molecular:360.43UDP-sugar pyrophosphorylase (BlUSP)
CAS:<p>BlUSP enzyme turns Glc-1-P into UDP-Glucose, transferring uridyl from UTP and producing PPi.</p>Forma y color:SolidGalcuronokinase (AtGalAK)
<p>AtGalAK, a GHMP kinase, converts d-GalA to GalA-1-P using ATP.</p>Forma y color:SolidBiotin-Vitamin B12
<p>Biotin-Vitamin B12, a biotinylated form, is crucial for brain, nervous system function, and blood formation.</p>Fórmula:C73H102CoN16O16PSForma y color:SolidPeso molecular:1581.66DSPE-PEG1000-CGKRK
<p>DSPE-PEG1000-CGKRK is a PEG compound composed of DSPE and the cell-penetrating peptide (CGKRK). It is utilized for drug delivery.</p>Forma y color:Odour SolidN4-Acetylcytidine triphosphate
CAS:<p>N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription .</p>Fórmula:C11H18N3O15P3Pureza:98%Forma y color:SolidPeso molecular:525.19(S)-Higenamine
CAS:<p>(S)-Higenamine, a benzylisoquinoline precursor, forms from dopamine and 4-HPAA via NCS.</p>Fórmula:C16H17NO3Forma y color:SolidPeso molecular:271.316-Azathymine acid
CAS:<p>6-Azathymine is a metabolite of Pymetrozine, an insecticide targeting aphids and whiteflies by disrupting feeding.</p>Fórmula:C4H3N3O4Forma y color:SolidPeso molecular:157.08Lunine
CAS:<p>Lunine is a bioactive chemical.</p>Fórmula:C16H17NO4Forma y color:SolidPeso molecular:287.31L-Pyroglutamic acid β-naphthylamide
CAS:<p>L-Pyroglutamic acid β-naphthylamide (PYR) is a derivative of glutamic acid.</p>Fórmula:C15H14N2O2Forma y color:SolidPeso molecular:254.28Calcium gluconate monohydrate
CAS:<p>Calcium gluconate monohydrate is a useful organic compound for research related to life sciences. The catalog number is T35350 and the CAS number is 66905-23-5.</p>Fórmula:C6H16CaO8Pureza:98%Forma y color:SolidPeso molecular:256.264Adenylosuccinic acid tetraammonium
<p>Adenylosuccinic acid, orally active, is a purine ribonucleotide involved in nucleotide metabolism, may aid in DMD studies.</p>Fórmula:C14H30N9O11PForma y color:SolidPeso molecular:531.42Hydroxychloroquine Impurity F
CAS:<p>Hydroxychloroquine Impurity F, a byproduct, is an antimalarial that blocks TLR7/9 and inhibits SARS-CoV-2 in vitro.</p>Fórmula:C14H15ClN2Forma y color:SolidPeso molecular:246.74Febuxostat impurity 8
CAS:<p>Febuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Fórmula:C16H17NO4SForma y color:SolidPeso molecular:319.38Mersalyl
CAS:<p>Mersalyl is an organic mercurial diuretic.</p>Fórmula:C13H16HgNNaO6Forma y color:SolidPeso molecular:505.854Tetracosanoyl-sulfatide
CAS:<p>C24 3'-sulfo Galactosylceramide is a key myelin sulfatide, high in leukodystrophy patients, non-immunogenic compared to C24:1 variant.</p>Fórmula:C48H93NO11SForma y color:SolidPeso molecular:892.32Palitantin
CAS:<p>Palitantin is a useful organic compound for research related to life sciences. The catalog number is T125757 and the CAS number is 15265-28-8.</p>Fórmula:C14H22O4Forma y color:SolidPeso molecular:254.32611β-HSD1-IN-11
CAS:<p>11β-HSd1-in-11 is a potent and competitive inhibitor of 11-β-hydroxysteroid dehydrogenase 1 (11β-HSD1) IN rats and humans with IC50 values of 0.34 μM and 0.13</p>Fórmula:C15H11F3O3SPureza:99.61%Forma y color:SoildPeso molecular:328.31Coenzyme A
CAS:<p>Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.</p>Fórmula:C21H36N7O16P3SPureza:93.84%Forma y color:SolidPeso molecular:767.53N1-Acetylspermine
CAS:<p>N1-Acetylspermine, an endogenous metabolite found in urine, has applications in leukemia research [1] [2].</p>Fórmula:C12H28N4OForma y color:SolidPeso molecular:244.382-(2',3',4'-Trihydroxybutyl)quinoxaline
CAS:<p>2-(2',3',4'-Trihydroxybutyl)quinoxaline is a food metabolite.</p>Fórmula:C12H14N2O3Pureza:98%Forma y color:SolidPeso molecular:234.25UDP-3-O-acyl-GlcNAc
CAS:<p>UDP-3-O-acyl-GlcNAc is an E. coli metabolite for KDO biosynthesis.</p>Fórmula:C31H53N3O19P2Forma y color:SolidPeso molecular:833.71TSPO/Carbonic Anhydrase Modulator 1
<p>TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.</p>Fórmula:C35H51N3O3Forma y color:SolidPeso molecular:561.7985(S)-HPETE
CAS:<p>5(S)-HpETE is a PUFA made by 5-LO from arachidonic acid, metabolized into LTA4, a key leukotriene precursor.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.472Eremofortin A
CAS:<p>Eremofortin A, a metabolite, can be isolated from Penicillium roqueforti cultures [1].</p>Fórmula:C17H22O5Forma y color:SolidPeso molecular:306.35D-Fructose-13C6
CAS:<p>D-Fructose-13C6 can be used as an internal standard for the quantification of D-fructose by GC- or LC-MS.</p>Fórmula:C6H12O6Pureza:98% - 99.64%Forma y color:SolidPeso molecular:186.11

