Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(74 productos)
- CETP(20 productos)
- Anhídrido carbónico(185 productos)
- Caseína quinasa(137 productos)
- DHFR(34 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(289 productos)
- FAAH(65 productos)
- FXR(59 productos)
- Factor Xa(83 productos)
- Ácido graso sintasa(36 productos)
- Ferroptosis(218 productos)
- GR(3 productos)
- GSNOR(4 productos)
- Glucoquinasa(56 productos)
- HIF / HIF Prolilhidroxilasa(145 productos)
- HMG-CoA reductasa(33 productos)
- Hidroxilasa(34 productos)
- IDO(84 productos)
- LDL(8 productos)
- Lipasa(104 productos)
- Lípido(62 productos)
- Lipoxigenasa(132 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(38 productos)
- P450(6 productos)
- PAI-1(26 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(168 productos)
- Fosfolipasa(82 productos)
- ROR(43 productos)
- Receptor de retinoides(28 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(29 productos)
- Transportador(43 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 9054 productos de "Metabolismo"
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HBPC-GSH
CAS:HBPC-GSH, a derivative of glutathione, functions as an inhibitor for the glyoxalase system, specifically inhibiting cGloI and cGloII with IC50 values of 0.6μMFórmula:C17H23BrN4O8SForma y color:SolidPeso molecular:523.36MEY-003
MEY-003, an Autotaxin (ATX) inhibitor, exhibits EC50 values of 460 nM for hATX-β and 1.09 μM for hATX-ɣ (analysis with LPC18:1), demonstrating its potencyForma y color:Odour SolidN-Desmethyl imatinib mesylate
CAS:Norimatinib mesylate, N-Desmethyl imatinib metabolite, inhibits v-Abl, c-Kit, PDGFR.Fórmula:C29H33N7O4SForma y color:SolidPeso molecular:575.68Febuxostat n-butyl isomer
CAS:Febuxostat n-butyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .Fórmula:C16H16N2O3SForma y color:SolidPeso molecular:316.38(R)-ICMT-IN-3
(R)-ICMT-IN-3 (compound ent 2-27) functions as a potent inhibitor of ICMT, exhibiting an IC50 value of 0.01 μM [1].Forma y color:Odour Solidβ-Tetralone
CAS:<p>β-Tetralone (2-Tetralone) is a vital drug synthesis precursor with complex pharmacological properties in combating neurological disorders. Cost-effective and quality-assured.</p>Fórmula:C10H10OPureza:97.26% - 99.18%Forma y color:Clear To Yellow LiquidPeso molecular:146.19MTHFD2-IN-4
MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].Fórmula:C26H21F6N2O5Forma y color:SolidPeso molecular:555.45Adenosine 5'-succinate
CAS:Adenosine 5'-succinate, similar to AMP, inhibits taste receptors activated by Denatonium.Fórmula:C14H17N5O7Forma y color:SolidPeso molecular:367.318Diadenosine pentaphosphate pentasodium
CAS:Diadenosine pentaphosphate pentasodium, an endogenous purine from platelets and various cells, has vasoactive properties.Fórmula:C20H24N10Na5O22P5Forma y color:SolidPeso molecular:1026.28Malate dehydrogenase
CAS:Malate dehydrogenase catalyzes the mutual conversion of oxaloacetate and malate, and is associated with the oxidation/reduction of dinucleotide coenzymes [1] .Forma y color:SolidMK-8262
CAS:MK-8262: oral CETP inhibitor, potent (IC50 = 53 nM, log D = 5.3), may impact HDL/LDL and CHD research.Fórmula:C35H25F9N2O5Forma y color:SolidPeso molecular:724.58Caffeoylcalleryanin
CAS:Caffeoylcalleryanin demonstrated potent inhibitory activity against 15-lipoxygenase (15-LOX), with an IC50 value of 1.59 μM. Furthermore, ethanol extract from A. pulchra leaves (EEAPL) was found to contain compounds exhibiting antiviral properties, particularly effective against Dengue virus type 2 (DENV-2). Among these compounds, Caffeoylcalleryanin emerged as the most potent anti-DENV-2 agent, achieving a selectivity index (SI) of 20.0.Fórmula:C22H24O11Forma y color:SolidPeso molecular:464.4PKCζ/ι pseudosubstrate inhibitor
CAS:<p>PKCζ/ι pseudosubstrate inhibitor demonstrates comprehensive inhibitory activity across the protein kinase C (PKC) family and is associated with the induction of</p>Fórmula:C76H128N30O16Forma y color:SolidPeso molecular:1718.0213C C16 Sphingomyelin (d18:1/16:0)
CAS:<p>'13C-enriched C16 Sphingomyelin is a standard for quantifying C16 sphingomyelin by MS. Common in eggs; less in brain/milk; interacts with cholesterol.'</p>Fórmula:C39H79N2O6PForma y color:SolidPeso molecular:704.035α-Glucosidase-IN-87
α-Glucosidase-IN-87 (Compound 11c) is an orally active inhibitor of α-glucosidase with an IC50 of 119.7 μM. It exhibits hypoglycemic properties and is applicable in research on metabolic diseases such as diabetes.Forma y color:Odour SolidH-Pro-Phe-OH
CAS:<p>H-Pro-Phe-OH is a dipeptide formed from proline and phenylalanine, serving as a substrate for prolylase and in peptide synthesis.</p>Fórmula:C14H18N2O3Forma y color:SolidPeso molecular:262.30IETP2
CAS:<p>IETP2 targets low-density lipoprotein receptor-related protein 1 (LRP1) with a KD of 738 nM, making it useful for delivering drugs and imaging agents across the blood-labyrinth barrier (BLB).</p>Fórmula:C107H171N39O29Forma y color:SolidPeso molecular:2467.75α-Glucosidase-IN-54
CAS:<p>α-Glucosidase-IN-54 (compound 2) functions as an α-glucosidase inhibitor, exhibiting an IC 50 value of 0.011 mM, and is derived from Syzygium jambos (L.). This compound is employed in diabetes research [1].</p>Fórmula:C24H36O3Forma y color:SolidPeso molecular:372.54Nap-FF
CAS:<p>Nap-FF is a cell-penetrating dipeptide used in the preparation of hydrogel chemical sensors and for research in targeted drug delivery.</p>Fórmula:C30H28N2O4Forma y color:SolidPeso molecular:480.554N,S-Bis-Fmoc-Glutathione
CAS:<p>N,S-Bis-Fmoc-Glutathione is a potent inhibitor of glyoxalase II, exhibiting a K i of 0.32 mM [1].</p>Fórmula:C40H37N3O10SForma y color:SolidPeso molecular:751.8Methionylserine
CAS:<p>Methionylserine (H-MET-SER-OH), a dipeptide, binds hPEPT1 (Km 0.2 mM), inhibits ACE, used in hypertension research.</p>Fórmula:C8H16N2O4SForma y color:SolidPeso molecular:236.29Nicotinic Acid Adenine Dinucleotide
CAS:Nicotinic Acid Adenine Dinucleotide is a precursor of NAD (Nicotinamide adenine dinucleotide) and a substrate for glutamine-dependent NAD+ synthaseFórmula:C21H26N6O15P2Forma y color:SoildPeso molecular:664.41Octanoyl Coenzyme A (sodium salt)
Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.Fórmula:C29H49N7NaO17P3SForma y color:SolidPeso molecular:915.71N-Fmoc-D-glutamine
CAS:N-Fmoc-D-glutamine is Fmoc-protected alpha-glutamine. Alpha-glutamine is an α-amino acid and the most abundant free amino acid in human blood.Fórmula:C20H20N2O5Pureza:99.14%Peso molecular:368.38Lysylcysteine TFA
Lysylcysteine (L-Lysyl-L-cysteine)TFA is a dipeptide composed of lysine and cysteine.Fórmula:C13H21F6N3O7SForma y color:SolidPeso molecular:477.10044SY-640
CAS:SY-640, an acetamide derivative, strongly protects the liver and lessens Propionibacterium acnes and lipopolysaccharide-induced damage in mice.Fórmula:C11H13NO3Pureza:99.51% - 99.66%Forma y color:SolidPeso molecular:207.23Abz-Ser-Pro-3-nitro-Tyr
CAS:Abz-Ser-Pro-3-nitro-Tyr is the substrate of ACE2 (angiotensin-converting enzyme-2) [1] .Fórmula:C24H27N5O9Forma y color:SolidPeso molecular:529.5IPH5201
<p>IPH5201 is a human IgG1 monoclonal antibody (mAb) targeting ENTPD1/CD39. It enhances the accumulation of immunostimulatory ATP released by tumor cells undergoing combination chemotherapy (CT) and reduces the levels of immunosuppressive adenosine (Ado) in the tumor microenvironment (TME). IPH5201 is useful for research on antitumor immunity. Recommended isotype control: Human IgG1 kappa, Isotype Control.</p>Forma y color:Odour LiquidCIGB-300
CAS:<p>CIGB-300 (P15-Tat) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by disrupting the phosphorylation activity of protein kinase CK2. The compound induces apoptosis in various tumor cell lines, making it valuable for research in cancer therapy.</p>Fórmula:C127H215N53O30S3Forma y color:SolidPeso molecular:3060.6DSPE-PEG-Maleimide ammonium (MW 2000)
DSPE-PEG-Maleimide (ammonium) (MW 2000) is a compound containing DSPE phospholipids and maleimide, designed for the preparation of nanoscale lipid carriers. It is applicable in the study of drug delivery systems.Forma y color:Odour SolidNucleocidin
CAS:<p>Nucleocidin, an antitrypanosomal antibiotic, inhibits the transfer of labeled amino acids from S-RNA to protein.</p>Fórmula:C10H13FN6O6SPureza:98%Forma y color:SolidPeso molecular:364.31D-Threonine
CAS:<p>D-Threonine (H-D-Thr-OH) is one of the metabolites of Saccharomyces cerevisiae.</p>Fórmula:C4H9NO3Pureza:≥98%Forma y color:SolidPeso molecular:119.12PTP1B-IN-27
<p>PTP1B-IN-27 (Compound 7i) is an inhibitor of protein tyrosine phosphatase 1-B (PTP-1B) with an IC50 of 8.2 µM. Additionally, it inhibits α-glucosidase with an IC50 of 120 µM and exhibits competitive inhibition characteristics (Ki=118 µM).</p>Fórmula:C26H24FN7O2SPeso molecular:517.16962MPO-IN-7
MPO-IN-7 (compound MDC) is a myeloperoxidase inhibitor with IC50 values of 41 μM for α-glucosidase, 25 μM for dipeptidyl peptidase-4, and 4.5 μM for myeloperoxidase. MPO-IN-7 exhibits antioxidant and anti-inflammatory activities in vitro.Fórmula:C16H14N2O6Peso molecular:330.08519α-Glucosidase-IN-48
<p>α-Glucosidase-IN-48 (compound 9) is a potent inhibitor of α-Glucosidase, with an IC50 of 1.30 μM.</p>Fórmula:C15H9Cl2N5O3SPeso molecular:408.98032α-Glucosidase-IN-44
<p>α-Glucosidase-IN-44 (compound IT4) is an α-glucosidase inhibitor with an IC50 value of 2.35 μM. This compound is orally active and has the ability to reduce fasting blood glucose levels in diabetic mice.</p>Fórmula:C23H21N3O3SPeso molecular:419.13036Carbonic anhydrase/AChE-IN-2
<p>Carbonic anhydrase/AChE-IN-2 (compound 19) is a selective inhibitor of acetylcholinesterase (AChE) and carbonic anhydrase (CA), with inhibition efficiencies (Ei) of 8.54 nM, 13.54 nM, and 5.21 nM, respectively.</p>Fórmula:C17H12BrF3O2Peso molecular:383.99728ST6 Sialyltransferase 5
<p>ST6Sialyltransferase5 (EC:2.4.3.3, ST6GALNAC5, SIAT7E, ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) transfers sialic acid to N-acetylgalactosamine (GalNAc) residues. It may serve as a biomarker in cervical screening samples.</p>NAMPT activator-7
NAMPTactivator-7 (Compound 232) is an activator of nicotinamide phosphoribosyltransferase (NAMPT) with an EC50 of less than 0.5 μM. It effectively stimulates NAMPT in U2OS cells, demonstrating a cellular EC50 of less than 0.5 μM.Fórmula:C21H17ClN4O3Peso molecular:408.09892α-Amylase/α-Glucosidase-IN-13
α-Amylase/α-Glucosidase-IN-13 (Compound 5d) is a dual inhibitor of α-amylase and α-glucosidase, and is useful in diabetes research.Fórmula:C22H16N2O5Peso molecular:388.10592LTA4H-IN-4
<p>LTA4H-IN-4 (compound 3) is an orally active inhibitor of LTA4H. It exhibits an IC50 value of 156 μM against hERG and is applicable for inflammation-related research.</p>HSP90-IN-30
<p>HSP90-IN-30 (compound 3e) inhibits the activity of the HSP90 molecular chaperone. Under hypoxic conditions, HSP90-IN-30 suppresses HIF-1 transcriptional activity with an IC50 value of 2.16 μM.</p>Fórmula:C20H39B12N4O2Peso molecular:499.41897hCAIX/XII-IN-11
<p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>Fórmula:C13H10FN3O4Peso molecular:291.06553Human Factor VIIa
HumanFactor VIIa is a vitamin K-dependent serine protease involved in the blood coagulation process. It has the ability to activate coagulation factor X, which in turn converts prothrombin into thrombin, leading to the transformation of fibrinogen into fibrin and resulting in the formation of blood clots. HumanFactor VIIa holds potential for improving hemophilia.α-Glucosidase-IN-60
α-Glucosidase-IN-60 (Compound 5k) acts as a competitive inhibitor of α-Glucosidase, with an IC50 of 10.8 μM.Fórmula:C23H14N2O5Peso molecular:398.09027α-Glucosidase-IN-57
α-Glucosidase-IN-57 (Compound 10c) is a competitive, orally active α-glucosidase inhibitor with an IC50 of 0.180 μM and a Ki of 0.15 μM. It effectively reduces fasting and overall blood glucose levels in mice, making it suitable for antidiabetic research.Fórmula:C32H23FN4OSPeso molecular:530.15766PR280
<p>PR280 is a potent inhibitor of dihydroceramide desaturase 1 (Des1) with an IC50 of 700 nM. It forms hydrogen bonds with amino acid residues of Des1, while its cyclopropenone group may coordinate with the iron center, stabilizing its binding at Des1's active site. This inhibits the ceramide biosynthesis pathway, preventing dihydroceramide (dhCer) from converting into ceramide. PR280 can be used in research related to sphingolipid metabolism disorders, including cancer and metabolic diseases.</p>Fórmula:C27H49NO4Peso molecular:451.36616Conagenin
CAS:Conagenin is a small molecular immunomodulator isolated by Streptomyces roseosporus.Fórmula:C10H19NO6Pureza:98%Forma y color:SolidPeso molecular:249.26Triethyl phosphate
CAS:Triethyl phosphate is a chemical compound. It can be called "phosphoric acid, triethyl ester".Fórmula:C6H15O4PPureza:98%Forma y color:Clear LiquidPeso molecular:182.16Leucomyosuppressin
CAS:Leucomyosuppressin, isolated from head extracts of the cockroach Leucophaea maderae, inhibits evoked transmitter release at the mealworm neuromuscular junction.Fórmula:C59H84N16O15Pureza:98%Forma y color:SolidPeso molecular:1257.418
