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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

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Se han encontrado 8625 productos de "Metabolismo"

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  • Osteocalcin, bovine


    Osteocalcin, bovine is a vitamin K-dependent bone-specific protein, also known as bone gamma-carboxyglutamate protein (BGLAP). It is a small (49 amino acids) non-collagenous hormone.
    Fórmula:C263H372N66O82S2
    Peso molecular:5830.64094
  • Anticancer agent 232


    Anticanceragent 232 (compound 12f) is a sugar hybrid designed from 1-azide glycosides derived from d-glucose, d-galactose, and d-mannose. The IC50 values for this compound are 1.05 μM against MCF-7 cells and 18.03 μM for MDA-MB231 cells.
    Fórmula:C32H31BrN4O11
    Peso molecular:726.11727
  • Moth Cytochrome C (MCC) (88-103)

    CAS:
    <p>Moth Cytochrome C (88-103) peptide induces positive TCR selection in thymocytes; key for self-tolerant T cell development.</p>
    Fórmula:C79H133N23O25
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1805.04
  • CYP51-IN-17


    <p>CYP51-IN-17 (compound 7a) is a potent CYP51 inhibitor with an IC50 of 0.377 μg/mL. It exhibits significant fungicidal activity against B. cinerea, with an EC50 of 0.326 μg/mL.</p>
    Fórmula:C24H20N2O7
    Peso molecular:448.12705
  • Mefox

    CAS:
    <p>Mefox is a bioactive chemical.</p>
    Fórmula:C20H23N7O7
    Forma y color:Solid
    Peso molecular:473.44
  • 11-cis Retinol

    CAS:
    <p>11-cisRetinol, a vitamin A isomer, forms from a retinyl ester via RPE65. It's crucial for the visual cycle and cone pigment formation.</p>
    Fórmula:C20H30O
    Forma y color:Solid
    Peso molecular:286.459
  • Calcium gluconate monohydrate

    CAS:
    <p>Calcium gluconate monohydrate is a useful organic compound for research related to life sciences. The catalog number is T35350 and the CAS number is 66905-23-5.</p>
    Fórmula:C6H16CaO8
    Pureza:98%
    Forma y color:Solid
    Peso molecular:256.264
  • 1-Deoxysphingosine (m18:1(4E))

    CAS:
    <p>1-Deoxysphingosine, an atypical sphingolipid with a 4E double bond, is linked to increased levels in CIAP and DSPN patients.</p>
    Fórmula:C18H37NO
    Forma y color:Solid
    Peso molecular:283.5
  • Asperlactone

    CAS:
    <p>Asperlactone is a nematicidal, insecticidal, antibacterial, and antifungal polyketide metabolite produced from A. westerdijkiae.</p>
    Fórmula:C9H12O4
    Forma y color:Solid
    Peso molecular:184.191
  • (Rac)-BMS-816336


    <p>(Rac)-BMS-816336 is a racemic 11β-HSD1 inhibitor; IC50: 10 nM (human), 68 nM (mouse), metabolically stable.</p>
    Fórmula:C21H27NO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:341.44
  • α-Glucosidase-IN-60


    <p>α-Glucosidase-IN-60 (Compound 5k) acts as a competitive inhibitor of α-Glucosidase, with an IC50 of 10.8 μM.</p>
    Fórmula:C23H14N2O5
    Peso molecular:398.09027
  • AChE/BChE-IN-17


    <p>AChE/BChE-IN-17 (compound 8m) is a potent inhibitor of AChE and BChE, displaying IC50 values of 125.06 nM and 119.68 nM, respectively. Additionally, AChE/BChE-IN-17 inhibits α-glucosidase, with an IC50 of 41050 nM.</p>
    Fórmula:C28H25N3O4
    Peso molecular:467.18451
  • Alphitonin

    CAS:
    <p>Alphitonin: a flavonoid in L. leptolepis wood, metabolized from quercetin by E. ramulus in the gut.</p>
    Fórmula:C15H12O7
    Forma y color:Solid
    Peso molecular:304.25
  • hCAIX/XII-IN-11


    <p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>
    Fórmula:C13H10FN3O4
    Peso molecular:291.06553
  • HSP90-IN-30


    <p>HSP90-IN-30 (compound 3e) inhibits the activity of the HSP90 molecular chaperone. Under hypoxic conditions, HSP90-IN-30 suppresses HIF-1 transcriptional activity with an IC50 value of 2.16 μM.</p>
    Fórmula:C20H39B12N4O2
    Peso molecular:499.41897
  • IDO1-IN-24


    <p>IDO1-IN-24 (compound 2c) inhibits the production of IDO1 during cell assays, with an IC50 value of 17 μM.</p>
    Fórmula:C18H22N2O4
    Peso molecular:330.15796
  • 2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole, pregn-4-ene-3,20-dione deriv

    CAS:
    <p>2H-Naphth[2',1':4,5]indeno[1,2-d][1,3]dioxole derivative is a potent, lung-selective anti-inflammatory in Sprague Dawley rats.</p>
    Fórmula:C25H34F2O6
    Pureza:98.20%
    Forma y color:Soild
    Peso molecular:468.53
  • Cholesteryl arachidonate

    CAS:
    <p>Cholesteryl arachidonate is a human endogenous metabolite.</p>
    Fórmula:C47H76O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:673.11
  • PROTAC NAMPT Degrader-1


    <p>PROTACNAMPT Degrader-1 is an effective NAMPT-targeting PROTAC with a DC50 value of 217 nM. It exhibits antiproliferative activity, with an IC50 value of 0.12 μM against A2780 cells.</p>
    Fórmula:C57H69N13O8S2
    Peso molecular:1127.48335
  • α-Glucosidase-IN-65


    <p>α-Glucosidase-IN-65 (compound 5) is a Schiff base derivative of 3,4-dihydroxyphenylacetic acid. It acts as a potent α-glucosidase inhibitor with an IC50 of 12.84 μM.</p>
    Fórmula:C15H14N2O6
    Peso molecular:318.08519
  • Febuxostat impurity 6

    CAS:
    <p>Febuxostat impurity 6 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>
    Fórmula:C18H22N2O4S
    Forma y color:Solid
    Peso molecular:362.44
  • FASN-IN-4 tosylate

    CAS:
    <p>FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.</p>
    Fórmula:C33H35N3O7S2
    Forma y color:Solid
    Peso molecular:649.78
  • Ivabradine impurity 1

    CAS:
    <p>Ivabradine impurity 1, orally bioavailable HCN channel blocker.</p>
    Fórmula:C15H18BrNO3
    Forma y color:Solid
    Peso molecular:340.21
  • Lodenafil carbonate

    CAS:
    <p>Lodenafil carbonate is a prodrug, orally used as a PDE5 inhibitor for ED treatment.</p>
    Fórmula:C47H62N12O11S2
    Forma y color:Solid
    Peso molecular:1035.21
  • 11-epi-Chaetomugilin I

    CAS:
    <p>11-epi-Chaetomugilin I, from Chaetomium globosum, has cytotoxic effects against P388, HL-60, L1210 leukemia, and KB carcinoma cells.</p>
    Fórmula:C22H27ClO5
    Forma y color:Solid
    Peso molecular:406.9
  • Fmoc-Cys-Asp10 TFA


    <p>Fmoc-Cys-Asp10 (TFA) is a non-releasable oligopeptide linker involved in synthesizing releasable oligopeptide linkers. These releasable linkers are used to deliver drugs to fracture-targeting oligopeptides, thereby reducing the healing time of fractured femurs.</p>
    Fórmula:C60H68F3N11O36S
    Peso molecular:1607.35012
  • TPH1-IN-1


    <p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>
    Fórmula:C21H18N6O4S
    Forma y color:Solid
    Peso molecular:450.47
  • Amastatin hydrochloride

    CAS:
    <p>Amastatin HCl is an inhibitor of aminopeptidase. It also induces vasoconstriction.</p>
    Fórmula:C21H39ClN4O8
    Forma y color:White To Off-White Powder
    Peso molecular:511.01
  • DSPE-PEG5000-R9


    <p>DSPE-PEG5000-R9 is a PEG compound composed of DSPE and the polyarginine-9 peptide (R9) peptide, applicable for drug delivery.</p>
    Forma y color:Odour Solid
  • CETP-IN-4

    CAS:
    <p>CETP-IN-4 is a cholesteryl ester transfer protein (CETP) inhibitor.</p>
    Fórmula:C36H28F9N3O4
    Forma y color:Solid
    Peso molecular:737.623
  • N4-Acetylcytidine triphosphate sodium

    CAS:
    <p>N4-Acetylcytidine triphosphate sodium is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription.</p>
    Fórmula:C11H18N3Na4O15P3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:617.15
  • Z-Thioprolyl-Thiazolidine

    CAS:
    <p>Z-Thioprolyl-Thiazolidine is a potent, specific inhibitor of bovine brain prolyl endopeptidase, demonstrating an inhibition constant (K i value) of 0.36 nM [1].</p>
    Fórmula:C15H18N2O3S2
    Forma y color:Solid
    Peso molecular:338.45
  • Coenzyme Q6

    CAS:
    <p>Coenzyme Q6, also Ubiquinone 30, is a benzoquinone lipid aiding respiration and acting as an antioxidant.</p>
    Fórmula:C39H58O4
    Forma y color:Solid
    Peso molecular:590.88
  • 10'-Desmethoxystreptonigrin

    CAS:
    <p>'10'-Desmethoxystreptonigrin antibiotic derived from streptonigrin combats various bacteria and cancer cells, and inhibits p21ras farnesylation (IC50 = 21 nM).</p>
    Fórmula:C24H20N4O7
    Forma y color:Solid
    Peso molecular:476.445
  • 11-trans Leukotriene C4

    CAS:
    <p>11-trans LTC4 is a C-11 isomer of LTC4, forms slowly on storage, is less common but similarly potent in contractions, pKis: 6.42 (LTC4), 6.58 (11-trans).</p>
    Fórmula:C30H47N3O9S
    Forma y color:Solid
    Peso molecular:625.78
  • Enniatin A

    CAS:
    <p>Enniatin A, a Fusarium toxin, blocks rat liver ACAT with 22 μM IC50.</p>
    Fórmula:C36H63N3O9
    Pureza:98%
    Forma y color:Solid
    Peso molecular:681.9
  • DSPE-PEG1000-CTT2


    <p>DSPE-PEG1000-CTT2 is a PEG compound comprised of DSPE and a gelatinase inhibitor [CTT2 (CTTHWGFTLC)]. The CTT2 (CTTHWGFTLC) peptide is capable of specifically targeting tumors. DSPE-PEG1000-CTT2 can be utilized for drug delivery.</p>
    Forma y color:Odour Solid
  • Aculene D

    CAS:
    <p>Aculene D, a fungal metabolite, inhibits quorum sensing in C. violaceum CV026, reducing violacein at low concentrations.</p>
    Fórmula:C14H20O2
    Forma y color:Solid
    Peso molecular:220.31
  • ER 50891 quarterhydrate


    <p>ER 50891 quarterhydrate is a potent RARα (retinoic acid receptor α) antagonist that markedly diminishes the inhibitory effects of ATRA (all-trans retinoic acid</p>
    Fórmula:C29H24N2O2H2O
    Forma y color:Solid
    Peso molecular:437.02
  • 1-Palmitoyl-2-linoleoyl PE

    CAS:
    <p>Phosphatidylethanolamine PLPE: a cell membrane component, studied for anandamide biosynthesis, sPLA2-IIA activity substrate.</p>
    Fórmula:C39H74NO8P
    Forma y color:Solid
    Peso molecular:715.994
  • Ozolinone

    CAS:
    <p>Ozolinone, an etozoline metabolite, is a loop diuretic treating hypertension and edema.</p>
    Fórmula:C11H16N2O3S
    Forma y color:Solid
    Peso molecular:256.32
  • Mastoparan

    CAS:
    <p>Mastoparan is a peptide toxin from wasp venom. It has the chemical structure Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2.</p>
    Fórmula:C70H131N19O15
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1478.91
  • DSPE-PEG1000-KAA


    <p>DSPE-PEG1000-KAA is a PEG compound comprised of DSPE and the CKAAKNK (KAA) peptide. The CKAAKNK peptide specifically binds to tumor vasculature in RIP-Tag2 transgenic mice. DSPE-PEG1000-KAA is applicable for drug delivery.</p>
    Forma y color:Odour Solid
  • Eremofortin A

    CAS:
    <p>Eremofortin A, a metabolite, can be isolated from Penicillium roqueforti cultures [1].</p>
    Fórmula:C17H22O5
    Forma y color:Solid
    Peso molecular:306.35
  • Isariin C

    CAS:
    <p>Isariin C is a flavonoid glucoside derived from the Epimedium plant genus. It stimulates angiogenesis and exhibits antioxidant activity.</p>
    Fórmula:C28H49N5O7
    Forma y color:Solid
    Peso molecular:567.72
  • DSPE-PEG5000-NYZL1


    <p>DSPE-PEG5000-NYZL1 is a PEG compound composed of DSPE and NYZL1, where NYZL1 specifically binds to bladder cancer tissues and cells. DSPE-PEG5000-NYZL1 is applicable for drug delivery.</p>
    Forma y color:Odour Solid
  • DSPE-PEG5000-ESBP


    <p>DSPE-PEG5000-ESBP is a PEG compound composed of DSPE and E-selectin binding peptide (ESBP). Acting as a tumor-targeting peptide, ESBP has the ability to specifically recognize and bind to receptors or markers on the surface of tumor cells.</p>
    Forma y color:Odour Solid
  • Benzo[b]furan-2-carboxaldehyde

    CAS:
    <p>Benzo[b]furan-2-carboxaldehyde is a CYP2A6 inhibitor and can be used in biochemical experiments and drug synthesis.</p>
    Fórmula:C9H6O2
    Pureza:98.86%
    Forma y color:Solid
    Peso molecular:146.14
  • DSPE-PEG1000-CSTSMLKAC


    <p>DSPE-PEG1000-CSTSMLKAC is a PEG compound composed of DSPE and CSTSMLKAC. The CSTSMLKAC component facilitates phage-mediated targeting to ischemic cardiac tissue. DSPE-PEG1000-CSTSMLKAC is applicable in drug delivery.</p>
    Forma y color:Odour Solid
  • Spaglumic acid acetate


    <p>Spaglumic acid acetate (Isospaglumic acid acetate) is a neuropeptide found in millimolar concentrations in brain.</p>
    Fórmula:C13H20N2O10
    Pureza:99.49%
    Forma y color:Solid
    Peso molecular:364.31