Metabolismo

Tryptophan, N-indol-3-ylacetyl- (6CI) (Indole-3-acetyl-L-tryptophan) is involved in regulatory mechanisms for the control of auxin activity during physiological

KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,)

AG-120 (racemic) is an oral IDH1 inhibitor with potential anti-cancer effects.

1-Naphthaleneacetic acid potassium salt (1-NAA Potassium Salt) is a synthetic phytogrowth hormone that promotes plant growth and a PLA2 inhibitor.

Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.

Eliglustat (Genz 99067) is an oral inhibitor of glucosylceramide synthase which is used in the therapy of type 1 Gaucher disease.

Glutamyl-glutamic acid (Glu-glu) is an Interpeptide Bridge in the Murein of Some Micrococci and Arthrobacter sp..

Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)

Vorasidenib (PVM/MA) is an inhibitor of mutant isocitrate dehydrogenase (IDH; IC50s = 31.9 and 31.7 nM for IDH1R132H and IDH2R140Q, respectively)

SN 6 (SN6) is a selective Na+/Ca2+ exchanger (NCX) inhibitor (IC50s of NCX1: 2.9 μM , NCX2: 16 μM ,NCX3: 8.6 μM)

CAY10698 is a 12-lipoxygenase inhibitor (12-LO; IC50 of 5.1 μM).

Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential

Norathiol (N-methyl-N-dithiocarboxyglucamine) is a metal chelator that promotes the excretion of 109Cd and may be used in the treatment of cadmium poisoning.

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse FE, and the Mouse FE standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Mouse FE. After TMB substrate solution is added, only those wells that contain Mouse FE and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse FE in the samples is then determined by comparing the OD of the samples to the standard curve.

Cyclic somatostatin (SRIF-14) is a cyclic tetradecapeptide regulating many endocrine and nervous system functions.

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human OPG, and the Human OPG standard plate wells that pre-coated using protein-related techniques are provided separately. Standard/Sample Diluent Buffer or samples are added to the appropriate microtiter plate wells ,then added a HRP-conjugated antibody specific to Human OPG. After TMB substrate solution is added, only those wells that contain Human OPG and HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human OPG in the samples is then determined by comparing the OD of the samples to the standard curve.

PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.

Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.

Alcohol dehydrogenase is a widely distributed zinc-containing enzyme involved in the detoxification mechanism of environmental alcohols.