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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8597 productos de "Metabolismo"

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  • ICMT-IN-29

    CAS:
    <p>ICMT-IN-29, also known as compound 66, effectively inhibits ICMT with an IC50 value of 0.019 μM [1].</p>
    Fórmula:C20H27NO2S
    Forma y color:Solid
    Peso molecular:345.5
  • VU0364739

    CAS:
    <p>VU0364739, a selective phospholipase D2 (PLD2) inhibitor with an IC50 of 22 nM, effectively reduces cancer cell proliferation [1].</p>
    Fórmula:C26H27FN4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:446.52
  • BMS-986172

    CAS:
    <p>BMS-986172 is an orally active, highly selective inhibitor of MGAT2, demonstrating inhibitory concentrations (IC50) of 4.6 nM for human MGAT2 (hMGAT2) and 20 nM</p>
    Fórmula:C24H22F7N7O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:589.47
  • CAXII-IN-1

    CAS:
    <p>CAXII-IN-1, antitumor, selectively inhibits CA XII with Ki of 3.8 nM for hCA XII and 56 nM for hCA IX.</p>
    Fórmula:C13H7Cl2NO3S
    Forma y color:Solid
    Peso molecular:328.17
  • 1-Isopropyltryptophan

    CAS:
    <p>1-Isopropyltryptophan (1-IsoPT), an IDO1 inhibitor, suppresses the expression of IDO-1 and IDO-2 mRNA induced by IFN-γ stimulation [1].</p>
    Fórmula:C14H18N2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:246.3
  • PHD-IN-1

    CAS:
    <p>PHD-IN-1 (compound 80) serves as a potent PHD2 inhibitor, exhibiting an IC50 value of ≤5 nM.</p>
    Fórmula:C24H23N7O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:441.49
  • IDO1/TDO-IN-6

    CAS:
    <p>IDO1/TDO-IN-6 (compound 11) is a dual inhibitor targeting IDO1 and TDO, exhibiting IC50 values of 2.25 μM for IDO1 and 2.89 μM for TDO.</p>
    Fórmula:C20H17NO5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:351.35
  • ALP/Carbonic anhydrase-IN-1

    CAS:
    <p>Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline</p>
    Fórmula:C15H16N2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:224.3
  • CoPoP

    CAS:
    <p>CoPoP, a liposome-based vaccine adjuvant, holds potential for application in cancer research [1].</p>
    Fórmula:C57H80CoN5O9P
    Forma y color:Solid
    Peso molecular:1069.18
  • ICMT-IN-36

    CAS:
    <p>ICMT-IN-36 (compound 40) serves as an ICMT inhibitor, with an IC50 value of 0.181 μM [1].</p>
    Fórmula:C21H25Cl2NO
    Forma y color:Solid
    Peso molecular:378.34
  • CM-10-18

    CAS:
    <p>CM-10-18: potent ER α-glucosidase inhibitor, strong antiviral against hemorrhagic fever viruses, protects mice from dengue fatality.</p>
    Fórmula:C17H35NO5
    Forma y color:Solid
    Peso molecular:333.46
  • C82

    CAS:
    <p>C82 acts as an inhibitor of Mycobacterium tuberculosis (Mtb) cyclic dinucleotide phosphodiesterase (CdnP), with an IC50 value of 17.5 µM. This particular enzyme is responsible for breaking down cyclic di-AMP (c-di-AMP) into adenosine 5'-monophosphate (AMP). Notably, C82 demonstrates selectivity for Mtb CdnP over other bacterial cyclic dinucleotide phosphodiesterases (CDN PDEs) such as Yybt, RocR, and Group B Streptococcus (GBS) CdnP, as well as the mammalian CDN PDE ENPP1, and the viral CDN PDE poxin, showing effectiveness at a concentration of 200 µM.</p>
    Fórmula:C17H17N3O3S
    Forma y color:Solid
    Peso molecular:343.4
  • Sampatrilat

    CAS:
    <p>Sampatrilat, an oral vasopeptidase inhibitor, more potently blocks C-domain ACE (Ki=13.8 nM) over N-domain (Ki=171.9 nM).</p>
    Fórmula:C26H40N4O9S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:584.68
  • 17(S)-HpDHA

    CAS:
    <p>17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].</p>
    Fórmula:C22H32O4
    Forma y color:Solid
    Peso molecular:360.49
  • Quercetin 7-glucuronide

    CAS:
    <p>Quercetin 7-glucuronide (Quercetin 7-O-β-glucuronide), a Quercetin metabolite found in Madagascarian Uncarina species, has the capability to inhibit LDL</p>
    Fórmula:C21H18O13
    Pureza:98%
    Forma y color:Solid
    Peso molecular:478.36
  • LFHP-1c

    CAS:
    <p>LFHP-1c, a neuroprotective PGAM5 inhibitor, demonstrates efficacy in preserving blood-brain barrier integrity following ischemic stroke.</p>
    Fórmula:C55H64N6O4
    Pureza:98.07%
    Forma y color:Solid
    Peso molecular:873.13
  • DOG-IM4

    CAS:
    <p>DOG-IM4 is a chemical compound instrumental in synthesizing nanoparticles for delivering antigen-encoding nucleic acids, targeting a broad range of conditions including autoimmune diseases, rare blood or metabolic disorders, allergies, cancer, and infectious diseases [1].</p>
    Fórmula:C51H95N3O7
    Forma y color:Solid
    Peso molecular:862.32
  • PPACK

    CAS:
    <p>PPACK: synthetic peptide, irreversibly inhibits thrombin (Ki = 0.24 nM), prevents platelet activation.</p>
    Fórmula:C21H31ClN6O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:450.96
  • 1-Palmitoyl-2-Oleoyl-sn-glycero-3-PA

    CAS:
    <p>1-Palmitoyl-2-oleoyl-sn-glycero-3-PA (1,2-POPA) is a phospholipid featuring a palmitic acid (16:0) chain that is saturated and an oleic acid (18:1) chain that is monounsaturated, positioned at the sn-1 and sn-2 locations, respectively. This compound is utilized in creating micelles, liposomes, and various artificial membrane forms.</p>
    Fórmula:C37H71O8P
    Forma y color:Solid
    Peso molecular:674.9
  • Anticancer agent 121

    CAS:
    <p>Anticancer agent 121, a human lactate dehydrogenase A (hLDHA) inhibitor, exhibits potent anticancer activities, suitable for use in anticancer research [1].</p>
    Fórmula:C19H18N2O3S
    Forma y color:Solid
    Peso molecular:354.42