Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(42 productos)
- Aminopeptidasa(76 productos)
- CETP(20 productos)
- Anhídrido carbónico(196 productos)
- Caseína quinasa(138 productos)
- DHFR(32 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(302 productos)
- FAAH(64 productos)
- FXR(62 productos)
- Factor Xa(85 productos)
- Ácido graso sintasa(37 productos)
- Ferroptosis(226 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(57 productos)
- HIF / HIF Prolilhidroxilasa(146 productos)
- HMG-CoA reductasa(34 productos)
- Hidroxilasa(36 productos)
- IDO(84 productos)
- LDL(7 productos)
- Lipasa(107 productos)
- Lípido(61 productos)
- Lipoxigenasa(134 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(40 productos)
- P450(6 productos)
- PAI-1(26 productos)
- PDE(169 productos)
- PED(1 productos)
- PKM(17 productos)
- PPAR(170 productos)
- Fosfolipasa(86 productos)
- ROR(47 productos)
- Receptor de retinoides(22 productos)
- SGK(10 productos)
- Tiorredoxina(12 productos)
- Transferasa(29 productos)
- Transportador(45 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 9185 productos de "Metabolismo"
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Lp-PLA2-IN-2
CAS:Lp-PLA2-IN-2 is a selective and potent lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor, with an IC50 0f 120 nM for recombinant human Lp-PLA2.Fórmula:C19H23FN2O4SPureza:98%Forma y color:SolidPeso molecular:394.46EMD638683 S-Form
CAS:EMD638683 is a highly selective SGK1 inhibitor with IC50 of 3 μM. EMD638683 S-Form is the S-form of EMD638683.Fórmula:C18H18F2N2O4Forma y color:SolidPeso molecular:364.34Docosatrienoic Acid
CAS:Docosatrienoic acid is a rare omega-3 fatty acid; Ki value is 5×M, which inhibits the binding of LTB4 to porcine neutrophil membrane.Fórmula:C22H38O2Pureza:98%Forma y color:SolidPeso molecular:334.545α-Androstan-3β-ol
CAS:5α-Androstan-3β-ol, a steroidal androgen, demonstrates selective interaction with cellular components, showing affinity for the androgen receptor (AR) with an IC50 of 1.7 µM and activating the pregnane X receptor (PXR) in HepG2 cells with an EC50 of 0.8 µM. It selectively inhibits the hydroxylase activities of 16α- and 6β-hydroxylase over 16β- or 7α-hydroxylase, with IC50 values of 70 and 110 µM, compared to >150 µM for the latter enzymes, indicating a specificity in its enzyme inhibition profile. Additionally, administration of this compound at a dosage of 30 mg/kg results in a decrease in testis weight and sperm production in mice, highlighting its biological effects on male reproductive parameters.Fórmula:C19H32OForma y color:SolidPeso molecular:276.46F1874-108
CAS:F1874-108 functions as an inhibitor of both brassinosteroid biosynthesis and signal transduction [1].Fórmula:C15H14N4O2SForma y color:SolidPeso molecular:314.36EMT inhibitor-2
CAS:EMT inhibitor-2 blocks CYP3A4 and CYP2C9 (IC50: 49.72, 5.54 μM) and prevents IL-1β/TGF-β-induced EMT.Fórmula:C24H26N2O8Forma y color:SolidPeso molecular:470.47PDE1-IN-2
CAS:PDE1-IN-2 is an PDE1 inhibitor(PDE1C, PDE1B and PDE1A with IC50 values of 6, 140 and 164 nM, respectvely).Fórmula:C16H21BrN4O2Pureza:98%Forma y color:SolidPeso molecular:381.273'-hydroxy Lidocaine
CAS:3'-Hydroxy Lidocaine, an active metabolite of Lidocaine, is produced through the metabolism by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4.Fórmula:C14H22N2O2Forma y color:SolidPeso molecular:250.342Enpp-1-IN-4
CAS:Enpp-1-IN-4: potent enpp-1 inhibitor with potential in cancer research. See patent WO2019177971A1, compound 1.Fórmula:C19H19N5O5SForma y color:SolidPeso molecular:429.45Brodimoprim
CAS:Brodimoprim is an inhibitor of dihydrofolate reductase(DHFR).Fórmula:C13H15BrN4O2Pureza:98% - 99.71%Forma y color:SolidPeso molecular:339.19Ganciclovir triphosphate
CAS:Ganciclovir triphosphate: synthetic 2'-deoxy-guanosine analog, treats/prevents CMV, IC50 of 0.01 μM, effective across species.Fórmula:C9H16N5O13P3Forma y color:SolidPeso molecular:495.17Methyl γ-Linolenyl Fluorophosphonate
CAS:MγLnFP, an analog of methyl arachidonyl fluozophosphonate (MAFP), holds significance in pharmacological research due to its potential as an inhibitor of phospholipases, FAAH, and its role as a CB receptor ligand. However, the properties and effects of the γ-linolenyl variant of MAFP remain to be fully explored.Fórmula:C19H34FO2PForma y color:SolidPeso molecular:344.451(2'S)-Nicotine-1-oxide
CAS:(2'S)-Nicotine-1-oxide, a nicotine metabolite, arises from the liver's metabolism of nicotine via the cytochrome P450 (CYP) isoform CYP2A6. It has been identified in human sperm and semen.Fórmula:C10H14N2OForma y color:SolidPeso molecular:178.235Lignoceroyl Ethanolamide
CAS:Lignoceroyl ethanolamide, a fatty N-acyl ethanolamine within the endocannabinoid family, is derived from lignoceric acid, which is found in relatively high concentrations in rat cerebrospinal fluid. However, the specific function and significance of this metabolite remain unclear.Fórmula:C26H53NO2Forma y color:SolidPeso molecular:411.7151,3-Dioleoyl-2-Myristoyl Glycerol
CAS:1,3-Dioleoyl-2-myristoyl glycerol, a triacylglycerol, features oleic acid at the sn-1 and sn-3 positions and myristic acid at the sn-2 position, and is identified in palm oil.Fórmula:C53H98O6Forma y color:SolidPeso molecular:831.341-Linoleoyl-3-α-Linolenoyl-rac-glycerol
CAS:1-Linoleoyl-3-α-linolenoyl-rac-glycerol, a diacylglycerol, features linoleic acid at the sn-1 position and α-linolenic acid at the sn-3 position. This compound is identified in olive oil that has undergone lipase-catalyzed glycerolysis, utilizing immobilized lipase B derived from C. antarctica.Fórmula:C39H66O5Forma y color:SolidPeso molecular:614.94TA-270
CAS:TA-720, a 5-lipoxygenase inhibitor, is used potentially for the treatment of asthma.Fórmula:C29H36N2O7Forma y color:SolidPeso molecular:524.611,3-Dioleoyl Glycerol
CAS:1,3-Dioleoyl glycerol, a diacylglycerol with oleic acid at the sn-1 and sn-3 positions, activates protein kinase C (PKC) by approximately 30% at a concentration of 50 μM.Fórmula:C39H72O5Forma y color:SolidPeso molecular:620.99N-didesmethyl Loperamide
CAS:N-didesmethyl Loperamide, an active metabolite of the peripheral μ1-opioid receptor agonist loperamide, impedes electrically induced contractions in isolatedFórmula:C27H29ClN2O2Forma y color:SolidPeso molecular:448.98Palmitoleic Acid sodium
CAS:Palmitoleic acid, an ω-7 monounsaturated fatty acid found in macadamia and sea buckthorn oils, enhances both basal and insulin-stimulated glucose uptake, as well as Glut4 protein levels in 3T3-L1 adipocytes at a 200 µM concentration. Ex vivo, at a dosage of 300 mg/kg per day, it significantly increases glucose uptake and both aerobic and anaerobic glycolysis, while decreasing de novo fatty acid synthesis and the activity of lipogenic enzymes, specifically ATP citrate lyase (ACL) and glucose-6-phosphate dehydrogenase (G6PDH), in isolated murine adipocytes. Furthermore, the dietary administration of palmitoleic acid at 300 mg/kg mitigates high-fat diet-induced insulin resistance and liver inflammation in mice.Fórmula:C16H29O2NaForma y color:SolidPeso molecular:276.39
