Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(42 productos)
- Aminopeptidasa(76 productos)
- CETP(20 productos)
- Anhídrido carbónico(196 productos)
- Caseína quinasa(138 productos)
- DHFR(32 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(302 productos)
- FAAH(66 productos)
- FXR(62 productos)
- Factor Xa(87 productos)
- Ácido graso sintasa(37 productos)
- Ferroptosis(226 productos)
- GR(3 productos)
- GSNOR(4 productos)
- Glucoquinasa(57 productos)
- HIF / HIF Prolilhidroxilasa(146 productos)
- HMG-CoA reductasa(34 productos)
- Hidroxilasa(36 productos)
- IDO(84 productos)
- LDL(8 productos)
- Lipasa(107 productos)
- Lípido(61 productos)
- Lipoxigenasa(134 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(40 productos)
- P450(6 productos)
- PAI-1(26 productos)
- PDE(170 productos)
- PED(1 productos)
- PKM(17 productos)
- PPAR(170 productos)
- Fosfolipasa(84 productos)
- ROR(47 productos)
- Receptor de retinoides(26 productos)
- SGK(10 productos)
- Tiorredoxina(12 productos)
- Transferasa(29 productos)
- Transportador(45 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 9245 productos de "Metabolismo"
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4-MDM
CAS:4-MDM (4-Methoxydiphenylmethane) is an orally active anti-inflammatory compound that selectively enhances the aminopeptidase activity of leukotriene A4 hydrolase (LTA4H). By promoting the degradation of proline-glycine-proline by LTA4H, 4-MDM reduces neutrophil recruitment in the lungs, alleviating inflammation without affecting the epoxide hydrolase activity of LTA4H. This compound is useful for research in pulmonary diseases.
Fórmula:C14H14OForma y color:SolidPeso molecular:198.26RORγt inverse agonist 34
CAS:RORγt inverse agonist 34 (compound 5a) is an inverse agonist for RORγt, exhibiting an IC50 of 0.094 μM for the inhibition of RORγt-LBD. This compound is utilized in psoriasis research.Fórmula:C31H37N3O3SForma y color:SolidPeso molecular:531.709Benfooxythiamine
CAS:Benfooxythiamine is a transketolase (TKT) inhibitor that suppresses SARS-CoV-2 replication and enhances the activity of the glycolysis inhibitor 2DG. It exhibits antiviral properties.
Fórmula:C19H22N3O7PSForma y color:SolidPeso molecular:467.433Clopidogrel-β-D-glucuronide
CAS:Clopidogrel-β-D-glucuronide is a metabolite of Clopidogrel. It directly interacts with the CYP2C8 enzyme and strongly inhibits the hepatic enzyme CYP2C8.Fórmula:C21H22ClNO8SForma y color:SolidPeso molecular:483.919Mutant IDH1-IN-3
CAS:Mutant IDH1-IN-3 (Compound 1) is a selective allosteric inhibitor targeting the mutant isocitrate dehydrogenase 1 (IDH1), with an IC50 of 13 nM for R132HIDH1. It effectively suppresses the production of D-2-hydroxyglutarate (2HG) in cells and is applicable for research in oncology.Fórmula:C22H30N4OForma y color:SolidPeso molecular:366.5α-Glucosidase-IN-18
α-Glucosidase-IN-18 (7B) is an orally active inhibitor of α-glucosidase, displaying an IC 50 value of 3.96 μM.Fórmula:C23H19NO2SForma y color:SolidPeso molecular:373.47AChE/hCA I-IN-1
CAS:AChE/hCA I-IN-1 (Compound L3) is an inhibitor of acetylcholinesterase (AChE) and carbonic anhydrase (CA), effectively inhibiting AChE, hCA I, and hCA II with IC50 values of 302 nM, 265 nM, and 283 nM, respectively.Fórmula:C13H9BrNNaO4SForma y color:SolidPeso molecular:378.174Etamicastat
CAS:Etamicastat can be used in the research of cardiovascular diseases.Fórmula:C14H15F2N3OSPureza:98%Forma y color:SolidPeso molecular:311.35Omesdafexor
CAS:Omesdafexor is an FXR agonist that can be used to study diseases caused by liver disease or metabolic inflammation.Fórmula:C34H43N3O3Forma y color:SolidPeso molecular:541.726-trans-12-epi-Leukotriene B4
CAS:6-trans-12-epi-Leukotriene B4, a metabolite of arachidonic acid, serves as a potent anti-inflammatory agent.Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.47IDO1-IN-13
IDO1-IN-13 is a potent IDO1 inhibitor (IC50: 61.6 nM, EC50: 30 nM in HeLa) that reduces kyn/trp ratio by 51% in SK-OV-3 tumors.Fórmula:C20H16BrN5O2SForma y color:SolidPeso molecular:470.34CYP2C1/CYP2C19-IN-2
CYP2C1/CYP2C19-IN-2 is a potent inhibitor of CYP2C9/CYP2C19 without liver toxicity or genotoxicity and can be used to study Zika virus (ZIKV) infection.Fórmula:C27H28N2O6SForma y color:SolidPeso molecular:508.59Obicetrapib
CAS:Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.Fórmula:C32H31F9N4O5Pureza:99.26% - >99.99%Forma y color:SolidPeso molecular:722.6Lapaquistat acetate
CAS:Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor that reduces the cytotoxicity induced by statins in human skeletal muscle cells.Fórmula:C33H41ClN2O9Pureza:99.38% - 99.94%Forma y color:SolidPeso molecular:645.14Dual FAAH/sEH-IN-1
CAS:Dual FAAH/sEH-IN-1 inhibits both sEH (IC50: 9.6 nM) and FAAH (IC50: 7 nM), offering potent anti-inflammatory effects.
Fórmula:C25H22ClN3O3S2Pureza:99.89%Forma y color:SolidPeso molecular:512.04JNJ-6204
CAS:JNJ-6204 is a deuterated compound that efficiently inhibits CSNK1D and CSNK1E.Fórmula:C19H11D6FN6OPureza:97.42% - 99.87%Forma y color:SolidPeso molecular:370.41PREP inhibitor-1
CAS:PREP inhibitor-1 is a prolyl oligopeptidase (PREP) inhibitor for the study of Alzheimer's disease.Fórmula:C22H28N4O2Pureza:98.78%Forma y color:SoildPeso molecular:380.48DRB18
CAS:DRB18 inhibits GLUT proteins, altering glucose metabolism and inducing cancer cell death by G1/S arrest and oxidative stress.Fórmula:C22H23ClN2O2Pureza:99.54%Forma y color:SolidPeso molecular:382.88Ref: TM-T22317
1mg89,00€5mg215,00€10mg340,00€25mg687,00€50mg1.108,00€100mg1.485,00€500mg2.962,00€1mL*10mM (DMSO)236,00€WAY-213613 hydrochloride
CAS:WAY-213613 hydrochloride: potent, selective GLT-1/EAAT2 inhibitor (IC50 85 nM); weaker for EAAT1/3; inactive at glutamate receptors; research tool for CNS.Fórmula:C16H13BrF2N2O4Pureza:99.14% - 99.37%Forma y color:SoildPeso molecular:415.19Ref: TM-T13330
1mg38,00€5mg85,00€10mg97,00€25mg226,00€50mg379,00€100mg645,00€200mg873,00€1mL*10mM (DMSO)94,00€ALOX15-IN-2
CAS:ALOX15-IN-2: Potent ALOX15 inhibitor. IC50: 1.55 μM for LA; 2.79 μM for AA. Stops linoleic/arachidonic acid oxidation.Fórmula:C23H29N3O4SPureza:99.98%Forma y color:SolidPeso molecular:443.56Ref: TM-T62606
1mg48,00€5mg96,00€10mg169,00€25mg329,00€50mg567,00€100mg810,00€500mg1.644,00€1mL*10mM (DMSO)105,00€
