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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

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  • Acetyl-Tau Peptide (273-284) amide

    CAS:
    <p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>
    Fórmula:C64H116N18O17
    Forma y color:Solid
    Peso molecular:1409.72
  • (E/Z)-Sivopixant

    CAS:
    <p>(E/Z)-Sivopixant ((E/Z)-S-600918)is a potent P2X3 receptor antagonist, IC50 = 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research.</p>
    Fórmula:C25H22ClN5O5
    Pureza:99.82%
    Forma y color:Solid
    Peso molecular:507.93
  • ZL-1101


    <p>ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.</p>
    Forma y color:Odour Liquid
  • BuChE-IN-13


    <p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>
    Forma y color:Odour Solid
  • AChE-IN-86


    <p>AChE-IN-86 (Compound 6f) is an inhibitor of acetylcholinesterase (AChE) with an IC50 value of 25.33 μg/mL. This compound exerts its inhibitory effects by forming hydrogen bonds, π-π, and π-alkyl interactions with amino acid residues at the key catalytic site of AChE. AChE-IN-86 can be utilized in Alzheimer's disease research.</p>
    Fórmula:C28H27N3O6S
    Forma y color:Solid
    Peso molecular:533.595
  • TAT-CN21 (scrambled)


    <p>TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).</p>
    Forma y color:Odour Solid
  • RuBi-GABA

    CAS:
    <p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>
    Fórmula:C42H39F6N5O2P2Ru
    Pureza:98%
    Forma y color:Solid
    Peso molecular:922.8
  • Syntide 2 TFA


    Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.
    Fórmula:C70H123N20F3O20
    Forma y color:Solid
    Peso molecular:1621.84
  • BMY-14802

    CAS:
    <p>BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.</p>
    Fórmula:C18H22F2N4O
    Pureza:99.84%
    Forma y color:Soild
    Peso molecular:348.39
  • 2-Hydroxyalbrassitriol

    CAS:
    <p>2-Hydroxyalbrassitriol (Compound 6) is an AChE inhibitor with an IC 50 of 35.97 μM [1] .</p>
    Fórmula:C15H26O4
    Forma y color:Solid
    Peso molecular:270.36
  • MAO-IN-6


    <p>MAO-IN-6 (Compound 3f) is a reversible MAO-B inhibitor that can cross the blood-brain barrier, with an IC50 value of 0.09 μM. It also shows inhibitory activity against AChE and BChE, with IC50 values of 4.48 μM and 17.03 μM, respectively. MAO-IN-6 exhibits low cytotoxicity and is applicable in Alzheimer's disease research.</p>
    Fórmula:C22H14F3NO2
    Forma y color:Solid
    Peso molecular:381.35
  • (Rac)-Norcisapride

    CAS:
    <p>Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.</p>
    Fórmula:C14H20ClN3O3
    Pureza:99.32%
    Forma y color:Soild
    Peso molecular:313.78
  • β-Amyloid (1-11)

    CAS:
    <p>Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid</p>
    Fórmula:C56H76N16O22
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1325.3
  • MIDD0301

    CAS:
    <p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>
    Fórmula:C19H13BrFN3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:414.23
  • β-Amyloid (1-43)(human) TFA


    <p>β-Amyloid (1-43)(human) TFA exhibits greater aggregation tendencies and heightened toxicity compared to its well-established counterpart, Aβ1-42.</p>
    Fórmula:C209H319F3N56O64S
    Forma y color:Solid
    Peso molecular:4729.21
  • Anticonvulsant agent 9


    <p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>
    Fórmula:C22H24N4O2
    Forma y color:Solid
    Peso molecular:376.45
  • OXA(17-33) TFA


    <p>OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).</p>
    Fórmula:C81H126F3N23O24
    Forma y color:Solid
    Peso molecular:1863
  • Calmodulin Binding Peptide 1

    CAS:
    <p>Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.</p>
    Fórmula:C231H373N69O70S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:5301.1
  • 5-HT1AR/5-HT6R ligand-1


    <p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>
    Fórmula:C25H29ClN4O2S
    Forma y color:Solid
    Peso molecular:485.04
  • AChE-IN-34


    <p>AChE-IN-34 (compound 5l) is a potent, selective AChE inhibitor exhibiting an IC50 of 3.98 µM and negligible BChE inhibition.</p>
    Fórmula:C19H14N8O6
    Forma y color:Solid
    Peso molecular:450.36
  • AChE-IN-39


    <p>AChE-IN-39 (Compound 7c), with an IC50 value of 0.058 μM, is an acetylcholinesterase (AChE) inhibitor known for its DPPH scavenging activity and potential to</p>
    Fórmula:C19H15NO3
    Forma y color:Solid
    Peso molecular:305.33
  • DDC 2′,3′-O-disulfate


    <p>DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].</p>
    Fórmula:C17H16O11S2
    Forma y color:Solid
    Peso molecular:460.43
  • AChE/BuChE/MAO-B-IN-2


    <p>AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM,</p>
    Fórmula:C19H18FNO3
    Forma y color:Solid
    Peso molecular:327.35
  • Pozanicline hydrochloride


    <p>Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.</p>
    Fórmula:C11H17ClN2O
    Pureza:97.13% - 99.81%
    Forma y color:Solid
    Peso molecular:228.72
  • AChE-IN-29


    <p>AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric</p>
    Fórmula:C18H19BrN2O2
    Forma y color:Solid
    Peso molecular:375.26
  • (Rac)-5-Hydroxymethyl Tolterodine hydrochloride

    CAS:
    <p>(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.</p>
    Fórmula:C22H32ClNO2
    Forma y color:Solid
    Peso molecular:377.95
  • Aβ-IN-8


    <p>Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].</p>
    Fórmula:C22H16F3N3O3S
    Forma y color:Solid
    Peso molecular:459.44
  • AChE/BChE-IN-15


    <p>AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (</p>
    Fórmula:C29H30N6O3
    Forma y color:Solid
    Peso molecular:510.59
  • Notch 1 TFA


    <p>Notch 1 TFA encodes a member of the NOTCH family of proteins.</p>
    Fórmula:C64H98N15F3O25S3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1614.81
  • AChE-IN-87


    <p>AChE-IN-87 is an AChE inhibitor with an IC50 of 0.05 μM and a Ki of 16.93 nM. It exhibits no cytotoxicity toward 3T3 cells and is suitable for Alzheimer's disease (AD) research.</p>
    Fórmula:C32H39N3O12S2
    Forma y color:Solid
    Peso molecular:721.19752
  • Trontinemab

    CAS:
    <p>Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).</p>
    Pureza:96.77% - 99%
    Forma y color:Liquid
  • Ro60-0175

    CAS:
    <p>Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.</p>
    Fórmula:C11H12ClFN2
    Pureza:97.09%
    Forma y color:Solid
    Peso molecular:226.68
  • nAChR agonist CMPI hydrochloride

    CAS:
    <p>CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.</p>
    Fórmula:C18H20Cl2N4O
    Forma y color:Solid
    Peso molecular:379.29
  • Xanthohumol I


    <p>Xanthohumol I is a natural product that can be used as a reference standard.</p>
    Fórmula:C21H22O6
    Forma y color:Solid
    Peso molecular:370.401
  • AC 253

    CAS:
    <p>Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.</p>
    Fórmula:C122H196N40O39
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2847.11
  • (±)-LY367385

    CAS:
    <p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>
    Fórmula:C10H11NO4
    Forma y color:Solid
    Peso molecular:209.201
  • 2'-O-Succinyl-cAMP

    CAS:
    <p>2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2</p>
    Fórmula:C14H16N5O9P
    Forma y color:Solid
    Peso molecular:429.282
  • BuChE-IN-16


    <p>BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.</p>
    Fórmula:C16H22N2O3
    Forma y color:Solid
    Peso molecular:290.36
  • AChE/BChE-IN-22


    <p>AChE/BChE-IN-22 (compound 7) exhibits competitive inhibition against both AChE and BChE enzymes, with inhibition constants of 28.18 μM and 41.74 μM respectively.</p>
    Fórmula:C14H11F3N2O4S
    Forma y color:Solid
    Peso molecular:360.31
  • K1833


    <p>K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$.</p>
    Forma y color:Odour Solid
  • mHTT-IN-1

    CAS:
    <p>mHTT-IN-1 is a potent inhibitor of toxic mHTT, linked to Huntington's disease, with an EC50 of 46 nM.</p>
    Fórmula:C18H19N7OS
    Forma y color:Solid
    Peso molecular:381.45
  • α5-GABAA receptor modulator 1


    <p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>
    Fórmula:C21H20FN3O4
    Forma y color:Solid
    Peso molecular:397.4
  • Anticonvulsant agent 8


    <p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>
    Fórmula:C15H11N5O
    Forma y color:Solid
    Peso molecular:277.28
  • Epiboxidine

    CAS:
    <p>Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.</p>
    Fórmula:C10H14N2O
    Forma y color:Solid
    Peso molecular:178.23
  • Rasagiline 13C3 mesylate racemic

    CAS:
    <p>Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.</p>
    Fórmula:C13H17NO3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:270.32
  • N-Ethyl-N-(3-pyridylmethyl)amine

    CAS:
    <p>N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.</p>
    Fórmula:C8H12N2
    Pureza:99.65%
    Forma y color:Solid
    Peso molecular:136.19
  • CGP 35348

    CAS:
    <p>CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。</p>
    Fórmula:C8H20NO4P
    Pureza:≥98%
    Forma y color:Solid
    Peso molecular:225.22
  • CHF-5022

    CAS:
    <p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>
    Fórmula:C17H12F4O2
    Forma y color:Solid
    Peso molecular:324.27
  • β-Amyloid (1-17)

    CAS:
    <p>This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.</p>
    Fórmula:C90H130N28O29
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2068.2
  • β-Amyloid (12-20)

    CAS:
    <p>β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has</p>
    Fórmula:C57H83N15O11
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1154.36
  • Epiboxidine hydrochloride

    CAS:
    <p>Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.</p>
    Fórmula:C10H15ClN2O
    Forma y color:Solid
    Peso molecular:214.69
  • OXA(17-33)

    CAS:
    <p>Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.</p>
    Fórmula:C79H125N23O22
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1749
  • RA306


    <p>RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.</p>
    Forma y color:Odour Solid
  • Eletriptan

    CAS:
    <p>Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.</p>
    Fórmula:C22H26N2O2S
    Forma y color:Solid
    Peso molecular:382.52
  • Atagabalin

    CAS:
    <p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>
    Fórmula:C10H19NO2
    Forma y color:Solid
    Peso molecular:185.26
  • Moxonidine hydrochloride

    CAS:
    <p>Moxonidine Hydrochloride: selective I1 imidazoline receptor agonist, stronger than α2-AR; lowers blood pressure; central action.</p>
    Fórmula:C9H13Cl2N5O
    Forma y color:Solid
    Peso molecular:278.14
  • LY3020371

    CAS:
    <p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>
    Fórmula:C15H15F2NO5S
    Forma y color:Solid
    Peso molecular:359.34
  • SKF-83566 hydrochloride

    CAS:
    <p>SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.</p>
    Fórmula:C17H19BrClNO
    Pureza:99.27%
    Forma y color:Soild
    Peso molecular:368.69
  • R-(+)-Cotinine

    CAS:
    <p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>
    Fórmula:C10H12N2O
    Forma y color:Solid
    Peso molecular:176.22
  • Nitrazolam

    CAS:
    <p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>
    Fórmula:C17H13N5O2
    Forma y color:Solid
    Peso molecular:319.32
  • COX-2-IN-46


    <p>COX-2-IN-46 (compound 5m) serves as a potent anti-inflammatory and analgesic agent. It demonstrates a significant inhibitory action on COX-2, with an IC 50 value of 87.74 nM.</p>
    Fórmula:C28H19F2N3S
    Forma y color:Solid
    Peso molecular:467.53
  • Antidepressant agent 3


    <p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>
    Fórmula:C17H30ClN5O2S
    Forma y color:Solid
    Peso molecular:403.97
  • LBG20304


    <p>LBG20304 (compound 2s) serves as a ligand for the homologous GluK5 receptor, demonstrating an IC50 of 432 nM and exhibiting over 40-fold selectivity against the GluK1-3 isoforms. At concentrations below 10 μM, LBG20304 shows neither agonistic nor antagonistic effects on heterologous GluK2/5 receptors. However, at concentrations above 10 μM, it displays minimal agonist activity in neuronal slices (rat).</p>
    Fórmula:C19H18N4O5
    Forma y color:Solid
    Peso molecular:382.37
  • β-Amyloid (1-20)

    CAS:
    <p>This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.</p>
    Fórmula:C113H157N31O32
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2461.7
  • Tariquidar methanesulfonate hydrate

    CAS:
    <p>m-PEG8-Ms is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC compounds.</p>
    Fórmula:C40H58N4O18S2
    Pureza:98.13%
    Forma y color:Solid
    Peso molecular:947.04
  • 5H-Pyrido[4,3-b]indole

    CAS:
    <p>5H-Pyrido[4,3-b]indole is a potential AchE/ChE inhibitor with potential antiviral activity for the study of neurodegenerative diseases.</p>
    Fórmula:C11H8N2
    Pureza:99.6%
    Forma y color:Solid
    Peso molecular:168.2
  • Paynantheine

    CAS:
    <p>Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.</p>
    Fórmula:C23H28N2O4
    Forma y color:Solid
    Peso molecular:396.48
  • Salvianolic acid H

    CAS:
    <p>Salvianolic acid H is a strong inhibitor of acetylcholinesterase (AChE) [1].</p>
    Fórmula:C27H22O12
    Forma y color:Solid
    Peso molecular:538.46
  • α-Conotoxin imi

    CAS:
    <p>alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.</p>
    Fórmula:C52H78N20O15S4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1351.56
  • Bis-(-)-8-demethylmaritidine


    <p>Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1</p>
    Forma y color:Odour Solid
  • SAHM1

    CAS:
    <p>Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.</p>
    Fórmula:C94H162N36O23S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2196.58
  • AChE-IN-4


    <p>AChE-IN-4 is an acetylcholine esterase inhibitor (AChEI) with an IC50 value of 24.1 μM.</p>
    Fórmula:C32H25BrN6O4S
    Forma y color:Solid
    Peso molecular:669.55
  • (S)-Vamicamide

    CAS:
    <p>(S)-Vamicamide is an anti-anticholinergic compound.</p>
    Fórmula:C18H23N3O
    Pureza:99.48% - 99.65%
    Forma y color:Soild
    Peso molecular:297.39
  • MK-0969

    CAS:
    <p>MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.</p>
    Fórmula:C24H30F2N4O2
    Forma y color:Solid
    Peso molecular:444.52
  • Laniquidar TFA


    <p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>
    Fórmula:C39H37F3N4O5
    Pureza:99.85%
    Forma y color:Soild
    Peso molecular:698.73
  • Duloxetine D3 hydrochloride

    CAS:
    <p>Duloxetine D3 HCl is a deuterium-labeled SNRI, treats depression/GAD, Ki 4.6 nM.</p>
    Fórmula:C18H20ClNOS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:336.89
  • N-Methylcyclohexaneethaneamine

    CAS:
    <p>N-Methylcyclohexaneethaneamine is a useful organic compound for research related to life sciences.</p>
    Fórmula:C9H19N
    Forma y color:Solid
    Peso molecular:141.2539
  • Cloxacepride

    CAS:
    <p>cloxacepride is a CaM antagonist that is used to treat asthma disease.</p>
    Fórmula:C22H27Cl2N3O4
    Pureza:99.62%
    Forma y color:Solid
    Peso molecular:468.37
  • PD24


    <p>PD24 serves as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with inhibitory concentrations (IC50) of 1.72 μM for human</p>
    Fórmula:C24H22N2O6
    Forma y color:Solid
    Peso molecular:434.44
  • MGS0028

    CAS:
    <p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>
    Fórmula:C8H8FNO5
    Forma y color:Solid
    Peso molecular:217.15
  • (-)-Eseroline fumarate

    CAS:
    <p>(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.</p>
    Fórmula:C17H22N2O5
    Forma y color:Solid
    Peso molecular:334.37
  • BuChE-IN-21


    <p>BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.</p>
    Fórmula:C16H23NO2
    Forma y color:Solid
    Peso molecular:261.17288
  • 5-HT2A receptor agonist-5

    CAS:
    <p>5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.</p>
    Fórmula:C23H29N3O
    Forma y color:Solid
    Peso molecular:363.5
  • β-Amyloid (1-34)

    CAS:
    <p>This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.</p>
    Fórmula:C170H253N47O52
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3787.2
  • Doxacurium Chloride

    CAS:
    <p>Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.</p>
    Fórmula:C56H78ClN2O16
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1070.69
  • β-Amyloid (11-22)

    CAS:
    <p>β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s</p>
    Fórmula:C70H102N18O18
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1483.67
  • M 8218

    CAS:
    <p>M 8218 is a bioactive chemical.</p>
    Fórmula:C20H29NO2
    Forma y color:Solid
    Peso molecular:315.45
  • 2-Methyl-1-indanone

    CAS:
    <p>2-Methyl-1-indanone is an acetylcholinesterase inhibitor and can be used for biochemical experiments and drug synthesis.</p>
    Fórmula:C10H10O
    Pureza:96.6%
    Forma y color:Solid
    Peso molecular:146.19
  • Sintamil

    CAS:
    <p>Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.</p>
    Fórmula:C18H20ClN3O4
    Forma y color:Solid
    Peso molecular:377.82
  • Cannabidiolic acid methyl ester

    CAS:
    <p>Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.</p>
    Fórmula:C23H32O4
    Forma y color:Solid
    Peso molecular:372.5
  • p-HTAA

    CAS:
    <p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>
    Fórmula:C24H16O4S5
    Forma y color:Solid
    Peso molecular:528.71
  • Anagyrine hydrochloride

    CAS:
    <p>Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.</p>
    Fórmula:C15H21ClN2O
    Forma y color:Solid
    Peso molecular:280.79
  • Antipsychotic agent-2


    <p>Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.</p>
    Fórmula:C22H26FN5O
    Forma y color:Solid
    Peso molecular:395.47
  • LtIA-F


    <p>LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.</p>
    Fórmula:C86H121N25O22S4
    Forma y color:Solid
    Peso molecular:1985.31
  • β-Amyloid (1-9)

    CAS:
    <p>This is an N-terminal fragment of beta amyloid.</p>
    Fórmula:C42H60N14O17
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1033.01
  • FRM-024

    CAS:
    <p>FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment of</p>
    Fórmula:C22H22ClN5O2
    Forma y color:Solid
    Peso molecular:423.9
  • Methyl ganoderate A acetonide

    CAS:
    <p>Methyl ganoderate A from Ganoderma lucidum is a natural AChE inhibitor (IC50=18.35 μM) for Alzheimer's research.</p>
    Fórmula:C34H50O7
    Forma y color:Solid
    Peso molecular:570.76
  • Encecalinol

    CAS:
    <p>Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].</p>
    Fórmula:C14H18O3
    Forma y color:Solid
    Peso molecular:234.29
  • Fluphenazine-N-2-chloroethane (hydrochloride)

    CAS:
    <p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>
    Fórmula:C22H27Cl3F3N3S
    Forma y color:Solid
    Peso molecular:528.89
  • α-Conotoxin PIA

    CAS:
    <p>Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nM</p>
    Fórmula:C79H125N27O25S4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1981.3