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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5398 productos de "Neurociencia"

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  • COR659

    CAS:
    <p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>
    Fórmula:C16H16ClNO3S
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:337.82
  • Indeloxazine hydrochloride

    CAS:
    <p>Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.</p>
    Fórmula:C14H18ClNO2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:267.75
  • Cyclophostin

    CAS:
    <p>Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).</p>
    Fórmula:C8H11O6P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:234.14
  • Osemozotan Free Base

    CAS:
    <p>Osemozotan Free Base is a 5-HT(1A) receptor agonist.</p>
    Fórmula:C19H21NO5
    Forma y color:Solid
    Peso molecular:343.37
  • Pregnanolone sulfate (pyridinium)

    CAS:
    <p>Pregnanolone sulfate pyridinium, an endogenous neurosteroid, inhibits NMDA receptors and exhibits neuroprotective properties [1].</p>
    Fórmula:C26H39NO5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:477.66
  • Flesinoxan

    CAS:
    <p>Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).</p>
    Fórmula:C22H26FN3O4
    Forma y color:Solid
    Peso molecular:415.46
  • CP-122288

    CAS:
    <p>CP-122288: potent, selective 5-HT1B/D/F agonist; inhibits plasma protein extravasation, neurogenic inflammation.</p>
    Fórmula:C16H23N3O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:321.44
  • β-Secretase Inhibitor IV

    CAS:
    <p>β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).</p>
    Fórmula:C31H38N4O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:578.72
  • NAS-181

    CAS:
    <p>NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.</p>
    Fórmula:C20H30N2O7S
    Forma y color:Solid
    Peso molecular:442.53
  • Brasofensine Maleate

    CAS:
    <p>Brasofensine Maleate inhibits the monoamine re-uptake.</p>
    Fórmula:C20H24Cl2N2O5
    Forma y color:Solid
    Peso molecular:443.32
  • JNJ-46281222

    CAS:
    <p>JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.</p>
    Fórmula:C23H25F3N4
    Forma y color:Solid
    Peso molecular:414.47
  • Nevadistinel

    CAS:
    <p>Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, indicated for mitigating cognitive deficits</p>
    Fórmula:C15H18N2O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:274.32
  • Eslicarbazepine

    CAS:
    <p>Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.</p>
    Fórmula:C15H14N2O2
    Pureza:99.97%
    Forma y color:Off-White Solid
    Peso molecular:254.28
  • Mesembrine

    CAS:
    <p>Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).</p>
    Fórmula:C17H23NO3
    Forma y color:Solid
    Peso molecular:289.37
  • P11149

    CAS:
    <p>P11149: oral AChE inhibitor, crosses BBB, IC50 1.3 μM, based on Galanthamine, aims Alzheimer's research.</p>
    Fórmula:C27H34ClNO4
    Forma y color:Solid
    Peso molecular:472.02
  • rel-HDMP 28 hydrochloride

    CAS:
    <p>Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].</p>
    Fórmula:C18H22ClNO2
    Forma y color:Solid
    Peso molecular:319.83
  • mGAT-IN-1

    CAS:
    <p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>
    Fórmula:C28H34ClN3O2S2
    Forma y color:Solid
    Peso molecular:544.17
  • Pomaglumetad methionil hydrochloride

    CAS:
    <p>LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.</p>
    Fórmula:C12H19ClN2O7S2
    Pureza:98.57%
    Forma y color:Solid
    Peso molecular:402.87
  • 5-HT2A antagonist 1

    CAS:
    <p>5-HT2A antagonist 1, from US5728835A &amp; JP 1007727, may treat gastrointestinal and circulatory issues.</p>
    Fórmula:C26H28N4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:428.53
  • QR-0217

    CAS:
    <p>QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.</p>
    Fórmula:C19H13NO3
    Forma y color:Solid
    Peso molecular:303.31
  • TPA 023

    CAS:
    <p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>
    Fórmula:C20H22FN7O
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:395.43
  • Diproqualone

    CAS:
    <p>Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].</p>
    Fórmula:C12H14N2O3
    Forma y color:Solid
    Peso molecular:234.255
  • ADX71441

    CAS:
    <p>ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events &amp; volume, and may aid in alcoholism and bladder pain.</p>
    Fórmula:C19H15ClF2N4O4
    Forma y color:Solid
    Peso molecular:436.8
  • 5-HT2A receptor agonist-3

    CAS:
    <p>5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.</p>
    Fórmula:C21H26BrNO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:420.34
  • Calmidazolium chloride

    CAS:
    <p>Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.</p>
    Fórmula:C31H23Cl7N2O
    Pureza:98.53%
    Forma y color:Solid
    Peso molecular:687.7
  • Aβ/tau aggregation-IN-3

    CAS:
    <p>Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functional</p>
    Fórmula:C23H22N4O3
    Forma y color:Solid
    Peso molecular:402.45
  • LY-426965

    CAS:
    <p>LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.</p>
    Fórmula:C28H38N2O2
    Forma y color:Solid
    Peso molecular:434.61
  • AChE-IN-44

    CAS:
    <p>AChE-IN-44 (Compound Tap4), an AChE inhibitor, is convertible into its thiazole salt form known as Tat2 [1].</p>
    Fórmula:C31H38ClN3OS2
    Forma y color:Solid
    Peso molecular:568.24
  • UNC9994 hydrochloride

    CAS:
    <p>UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.</p>
    Fórmula:C21H23Cl3N2OS
    Forma y color:Solid
    Peso molecular:457.84
  • L-AP4

    CAS:
    <p>L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).</p>
    Fórmula:C4H10NO5P
    Pureza:98%
    Forma y color:White To Off-White Crystalline Powder
    Peso molecular:183.1
  • Gentisein

    CAS:
    <p>Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7</p>
    Fórmula:C13H8O5
    Pureza:96.89%
    Forma y color:Solid
    Peso molecular:244.2
  • L 663581

    CAS:
    <p>L 663581 is the benzodiazepine receptor partial agonist.</p>
    Fórmula:C17H16ClN5O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:357.79
  • (S)-Renzapride


    <p>(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.</p>
    Fórmula:C16H22ClN3O2
    Forma y color:Solid
    Peso molecular:323.82
  • A-424274

    CAS:
    <p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>
    Fórmula:C14H15N3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:225.29
  • mGAT3/4-IN-2

    CAS:
    <p>mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.</p>
    Fórmula:C26H32ClN3OS2
    Forma y color:Solid
    Peso molecular:502.13
  • mAChR antagonist 1

    CAS:
    <p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>
    Fórmula:C19H22N2O2
    Forma y color:Solid
    Peso molecular:310.39
  • Abaperidone

    CAS:
    <p>Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.</p>
    Fórmula:C25H25FN2O5
    Pureza:98.22%
    Forma y color:Solid
    Peso molecular:452.47
  • CGP-54626 free base

    CAS:
    CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).
    Fórmula:C18H28Cl2NO3P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:408.3
  • VU6005649

    CAS:
    <p>VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).</p>
    Fórmula:C16H12F5N3O
    Pureza:99.87%
    Forma y color:Solid
    Peso molecular:357.28
  • Afizagabar

    CAS:
    <p>Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.</p>
    Fórmula:C19H12FN3O2S
    Forma y color:Solid
    Peso molecular:365.38
  • GSM-1

    CAS:
    <p>GSM-1 is a modulator of γ-Secretase.</p>
    Fórmula:C26H31ClF3NO2
    Forma y color:Solid
    Peso molecular:481.98
  • L 687306

    CAS:
    <p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>
    Fórmula:C11H15N3O
    Forma y color:Solid
    Peso molecular:205.26
  • Octahydroaminoacridine succinate

    CAS:
    <p>Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.</p>
    Fórmula:C17H24N2O4
    Pureza:99.91%
    Forma y color:Solid
    Peso molecular:320.38
  • GR-127935

    CAS:
    <p>GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist.</p>
    Fórmula:C29H31N5O3
    Forma y color:Solid
    Peso molecular:497.59
  • AAK1-IN-4

    CAS:
    <p>AAK1-IN-4 selectively inhibits AAK1 with IC50 of 4.6 nM; penetrates CNS, oral bioactive, potential for studying neuropathic pain.</p>
    Fórmula:C20H28N4O3
    Forma y color:Solid
    Peso molecular:372.46
  • VU6012962

    CAS:
    <p>VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).</p>
    Fórmula:C21H19F3N4O4
    Pureza:99.61% - 99.74%
    Forma y color:Solid
    Peso molecular:448.4
  • Velusetrag

    CAS:
    <p>Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.</p>
    Fórmula:C25H36N4O5S
    Forma y color:Solid
    Peso molecular:504.64
  • 4-Chloro-L-phenylalanine

    CAS:
    <p>4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).</p>
    Fórmula:C9H10ClNO2
    Pureza:99.76% - 99.96%
    Forma y color:Solid
    Peso molecular:199.63
  • MIN-117

    CAS:
    <p>MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.</p>
    Fórmula:C25H26Cl3N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:538.85
  • PTAC oxalate

    CAS:
    <p>muscarinic receptor ligand</p>
    Fórmula:C14H21N3O4S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:359.46
  • Facinicline hydrochloride

    CAS:
    <p>Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).</p>
    Fórmula:C15H19ClN4O
    Pureza:98.70%
    Forma y color:Solid
    Peso molecular:306.79
  • N-Demethyl MK-6884

    CAS:
    <p>N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.</p>
    Fórmula:C24H23N5O
    Forma y color:Solid
    Peso molecular:397.47
  • P2X3 antagonist 38

    CAS:
    <p>Compound 38, also known as Compound 4, is a potent, orally active P2X3 antagonist that demonstrates inhibitory activity with IC50 values of 0.132 µM, 0.165 µM,</p>
    Fórmula:C22H25F3N6O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:478.47
  • RAGE/SERT-IN-1

    CAS:
    <p>RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM and</p>
    Fórmula:C38H41ClN4OS
    Forma y color:Solid
    Peso molecular:637.28
  • Biphenylindanone A

    CAS:
    <p>Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.</p>
    Fórmula:C30H30O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:454.56
  • BMT-124110

    CAS:
    <p>BMT-124110: AAK1 inhibitor, IC50=0.9 nM, pain relief. BMT-090605: BIKE inhibitor, IC50=17 nM; GAK inhibitor, IC50=99 nM.</p>
    Fórmula:C21H27N3O3
    Pureza:98.07%
    Forma y color:Solid
    Peso molecular:369.46
  • (+)-Bicuculline methiodide

    CAS:
    <p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>
    Fórmula:C21H20INO6
    Pureza:99.24%
    Forma y color:Solid
    Peso molecular:509.29
  • VU0453595

    CAS:
    <p>VU0453595 is a M1 positive allosteric modulator (PAM).</p>
    Fórmula:C18H15FN4O
    Pureza:99.91%
    Forma y color:Solid
    Peso molecular:322.34
  • LY 53857

    CAS:
    <p>LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.</p>
    Fórmula:C27H36N2O7
    Forma y color:Solid
    Peso molecular:500.592
  • CGP 64213

    CAS:
    <p>CGP 64213 is a GABAb receptor agonist.</p>
    Fórmula:C26H36IN2O7P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:646.45
  • CGP36216 hydrochloride

    CAS:
    <p>CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].</p>
    Fórmula:C5H15ClNO2P
    Forma y color:Solid
    Peso molecular:187.6
  • Brasofensine

    CAS:
    <p>Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.</p>
    Fórmula:C16H20Cl2N2O
    Forma y color:Solid
    Peso molecular:327.25
  • Piperidine-4-sulfonic acid

    CAS:
    <p>Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].</p>
    Fórmula:C5H11NO3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:165.21
  • C3

    CAS:
    <p>C3 functions as a selective inhibitor of monoamine oxidase B (MAO-B; IC50= 0.021 µM), demonstrating preference over monoamine oxidase A (MAO-A; IC50= 26.8 µM). This compound, at dosages of 0.1, 1, and 3 mg/kg, effectively counters MPTP-induced reductions in dopamine levels within the mouse brain.</p>
    Fórmula:C18H19FN2O2
    Forma y color:Solid
    Peso molecular:314.35
  • BACE1-IN-1

    CAS:
    <p>BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).</p>
    Fórmula:C18H14F3N5O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:389.33
  • Anti-amyloid agent-1

    CAS:
    <p>Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].</p>
    Fórmula:C21H17F3N2O3
    Forma y color:Solid
    Peso molecular:402.37
  • Fosthiazate

    CAS:
    <p>Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., by</p>
    Fórmula:C9H18NO3PS2
    Pureza:97.78%
    Forma y color:Solid
    Peso molecular:283.35
  • VU0029251

    CAS:
    <p>VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.</p>
    Fórmula:C10H11N3S2
    Forma y color:Solid
    Peso molecular:237.34
  • (±)-Fabesetron hydrochloride

    CAS:
    <p>FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.</p>
    Fórmula:C18H20ClN3O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:329.82
  • ASS234

    CAS:
    <p>ASS234 is a multi-target propylamine used in the treatment of Alzheimer's disease.</p>
    Fórmula:C29H37N3O
    Forma y color:Solid
    Peso molecular:443.62
  • FGIN-1-27

    CAS:
    <p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>
    Fórmula:C28H37FN2O
    Pureza:99.86%
    Forma y color:Solid
    Peso molecular:436.6
  • AMG-8718

    CAS:
    <p>AMG-8718, an oral BACE1 blocker (IC50: 0.0007 μM), also inhibits BACE2 (IC50: 0.005 μM), lowering CSF and Aβ40 brain levels.</p>
    Fórmula:C25H19FN4O3
    Forma y color:Solid
    Peso molecular:442.44
  • (2R,4R)-APDC

    CAS:
    <p>(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.</p>
    Fórmula:C6H10N2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:174.15
  • BMS-933043

    CAS:
    <p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) &amp; human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>
    Fórmula:C16H19N7O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:325.37
  • Befiradol

    CAS:
    <p>Befiradol (NLX-112) is an agonist of 5-HT1A receptor.</p>
    Fórmula:C20H22ClF2N3O
    Forma y color:Solid
    Peso molecular:393.86
  • Physostigmine hemisulfate

    CAS:
    <p>cholinesterase inhibitor</p>
    Fórmula:C15H21N302H204S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:324.39
  • PZ-II-029

    CAS:
    <p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>
    Fórmula:C18H15N3O3
    Pureza:99.79%
    Forma y color:Solid
    Peso molecular:321.33
  • Wf-516

    CAS:
    <p>Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant</p>
    Fórmula:C25H25Cl2N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:502.39
  • 5-HT2A&5-HT2C agonist-1

    CAS:
    <p>5-HT2A&amp;5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.</p>
    Fórmula:C14H20N2O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:232.32
  • Antioxidant agent-15

    CAS:
    <p>Antioxidant agent-15 (Compound 4) demonstrates potent antioxidant inhibition activity, exhibiting an IC50 value of 15.44 nM.</p>
    Fórmula:C19H14O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:274.31
  • LG 50643

    CAS:
    <p>LG 50643 is a muscarinic antagonist.</p>
    Fórmula:C24H34INO2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:495.44
  • Robalzotan

    CAS:
    <p>Robalzotan is a selective 5-HT1A receptor antagonist.</p>
    Fórmula:C18H23FN2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:318.39
  • (1α,1'S,4β)-Lanabecestat

    CAS:
    <p>(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay),</p>
    Fórmula:C26H28N4O
    Forma y color:Solid
    Peso molecular:412.53
  • PQM130

    CAS:
    <p>PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.</p>
    Fórmula:C23H27NO4
    Pureza:98.73%
    Forma y color:Solid
    Peso molecular:381.46
  • GR 125487 sulfamate

    CAS:
    <p>GR 125487 sulfamate is a 5-HT4 receptor antagonist.</p>
    Fórmula:C19H29FN4O8S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:524.58
  • VU 0255035

    CAS:
    <p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>
    Fórmula:C18H20N6O3S2
    Pureza:98.09% - 98.1%
    Forma y color:Solid
    Peso molecular:432.52
  • 3-Bromocytisine

    CAS:
    <p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>
    Fórmula:C11H13BrN2O
    Pureza:99.974%
    Forma y color:Solid
    Peso molecular:269.14
  • PZ-1190

    CAS:
    <p>PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].</p>
    Fórmula:C27H30N4O2S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:506.68
  • MAO-B-IN-27

    CAS:
    <p>MAO-B-IN-27 (Compound 12c), a monoamine oxidase B (MAO-B) inhibitor, exhibits a potent and selective inhibitory effect on hMAO-B, with an IC50 value of 8.9 nM,</p>
    Fórmula:C16H17ClF3NO
    Pureza:98%
    Forma y color:Solid
    Peso molecular:331.76
  • Cimicoxib

    CAS:
    <p>Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.</p>
    Fórmula:C16H13ClFN3O3S
    Pureza:98.22%
    Forma y color:Solid
    Peso molecular:381.81
  • AAK1-IN-2

    CAS:
    <p>AAK1-IN-2, a potent (IC50=5.8 nM) AAK1 inhibitor, selective &amp; brain-penetrant, is used for neuropathic pain studies.</p>
    Fórmula:C20H20N4
    Forma y color:Solid
    Peso molecular:316.4
  • CGP 54626 hydrochloride

    CAS:
    <p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>
    Fórmula:C18H29Cl3NO3P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:444.76
  • ELND007

    CAS:
    <p>ELND007 is a Gamma secretase inhibitor.</p>
    Fórmula:C19H14F4N4O2S
    Forma y color:Solid
    Peso molecular:438.4
  • VU0360172

    CAS:
    <p>VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).</p>
    Fórmula:C18H15FN2O
    Pureza:99.56%
    Forma y color:Solid
    Peso molecular:294.32
  • DU-125530

    CAS:
    <p>DU-125530 is a 5-HT1A receptor antagonist.</p>
    Fórmula:C23H26ClN3O5S
    Forma y color:Solid
    Peso molecular:491.99
  • NAS181

    CAS:
    <p>rat 5-HT1B receptor antagonist</p>
    Fórmula:C21H34N2O10S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:538.63
  • cis-PDA

    CAS:
    <p>cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.</p>
    Fórmula:C7H11NO4
    Pureza:98.71%
    Forma y color:White Solid
    Peso molecular:173.17
  • Tiotropium Bromide hydrate

    CAS:
    <p>Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.</p>
    Fórmula:C19H24BrNO5S2
    Pureza:98.44% - 99.41%
    Forma y color:Solid
    Peso molecular:490.43
  • GMA-839

    CAS:
    <p>GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.</p>
    Fórmula:C21H31F3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:388.46
  • NAD 299 hydrochloride

    CAS:
    <p>Selective, high affinity 5-HT1A receptor antagonist</p>
    Fórmula:C18H24ClFN2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:354.85