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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5398 productos de "Neurociencia"

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  • eeAChE-IN-2

    CAS:
    <p>eeAChE-IN-2 is a potent inhibitor of eeAChE, exhibiting inhibitory potency with an IC50 of 2 nM.</p>
    Fórmula:C37H40N8O5S
    Forma y color:Solid
    Peso molecular:708.83
  • VU 0255035

    CAS:
    <p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>
    Fórmula:C18H20N6O3S2
    Pureza:98.09% - 98.1%
    Forma y color:Solid
    Peso molecular:432.52
  • Mesembrine

    CAS:
    <p>Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).</p>
    Fórmula:C17H23NO3
    Forma y color:Solid
    Peso molecular:289.37
  • CGP-54626 free base

    CAS:
    CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).
    Fórmula:C18H28Cl2NO3P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:408.3
  • CP-409092

    CAS:
    <p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>
    Fórmula:C17H19N3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:297.35
  • LY2033298

    CAS:
    <p>LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.</p>
    Fórmula:C13H14ClN3O2S
    Pureza:99.06%
    Forma y color:Solid
    Peso molecular:311.79
  • U 89843A

    CAS:
    <p>U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.</p>
    Fórmula:C16H23N5
    Pureza:99.62%
    Forma y color:Solid
    Peso molecular:285.39
  • Muscarine tosylate

    CAS:
    <p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>
    Fórmula:C16H27NO5S
    Forma y color:Solid
    Peso molecular:345.45
  • GABAA receptor agent 2 TFA

    CAS:
    <p>Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.</p>
    Fórmula:C22H22F3N3O3
    Forma y color:Solid
    Peso molecular:433.42
  • (±)-Fabesetron hydrochloride

    CAS:
    <p>FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.</p>
    Fórmula:C18H20ClN3O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:329.82
  • BMS-983970

    CAS:
    <p>BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.</p>
    Fórmula:C26H26F4N4O3
    Forma y color:Solid
    Peso molecular:518.5
  • (S)-Renzapride


    <p>(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.</p>
    Fórmula:C16H22ClN3O2
    Forma y color:Solid
    Peso molecular:323.82
  • GMA-839

    CAS:
    <p>GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.</p>
    Fórmula:C21H31F3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:388.46
  • A-424274

    CAS:
    <p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>
    Fórmula:C14H15N3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:225.29
  • Befiradol

    CAS:
    <p>Befiradol (NLX-112) is an agonist of 5-HT1A receptor.</p>
    Fórmula:C20H22ClF2N3O
    Forma y color:Solid
    Peso molecular:393.86
  • mAChR antagonist 1

    CAS:
    <p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>
    Fórmula:C19H22N2O2
    Forma y color:Solid
    Peso molecular:310.39
  • 3-Bromocytisine

    CAS:
    <p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>
    Fórmula:C11H13BrN2O
    Pureza:99.974%
    Forma y color:Solid
    Peso molecular:269.14
  • L 687306

    CAS:
    <p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>
    Fórmula:C11H15N3O
    Forma y color:Solid
    Peso molecular:205.26
  • CGP 64213

    CAS:
    <p>CGP 64213 is a GABAb receptor agonist.</p>
    Fórmula:C26H36IN2O7P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:646.45
  • (1α,1'S,4β)-Lanabecestat

    CAS:
    <p>(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay),</p>
    Fórmula:C26H28N4O
    Forma y color:Solid
    Peso molecular:412.53
  • ASS234

    CAS:
    <p>ASS234 is a multi-target propylamine used in the treatment of Alzheimer's disease.</p>
    Fórmula:C29H37N3O
    Forma y color:Solid
    Peso molecular:443.62
  • KBR 2822

    CAS:
    <p>KBR 2822 is an inhibitor of esterase.</p>
    Fórmula:C9H15ClF3O3PS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:326.7
  • AChE-IN-44

    CAS:
    <p>AChE-IN-44 (Compound Tap4), an AChE inhibitor, is convertible into its thiazole salt form known as Tat2 [1].</p>
    Fórmula:C31H38ClN3OS2
    Forma y color:Solid
    Peso molecular:568.24
  • Afizagabar

    CAS:
    <p>Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.</p>
    Fórmula:C19H12FN3O2S
    Forma y color:Solid
    Peso molecular:365.38
  • NAS181

    CAS:
    <p>rat 5-HT1B receptor antagonist</p>
    Fórmula:C21H34N2O10S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:538.63
  • Lanabecestat

    CAS:
    <p>Lanabecestat (AZD3293) is a BACE1 inhibitor (Ki: 0.4 nM), Lanabecestat is used in the study of neurological diseases like Alzheimer's disease.</p>
    Fórmula:C26H28N4O
    Pureza:98.55%
    Forma y color:Solid
    Peso molecular:412.53
  • NAS-181

    CAS:
    <p>NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.</p>
    Fórmula:C20H30N2O7S
    Forma y color:Solid
    Peso molecular:442.53
  • FGIN-1-27

    CAS:
    <p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>
    Fórmula:C28H37FN2O
    Pureza:99.86%
    Forma y color:Solid
    Peso molecular:436.6
  • Brasofensine

    CAS:
    <p>Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.</p>
    Fórmula:C16H20Cl2N2O
    Forma y color:Solid
    Peso molecular:327.25
  • 5-HT2 agonist-1

    CAS:
    <p>Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.</p>
    Fórmula:C19H23ClN2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:346.85
  • PZ-1190

    CAS:
    <p>PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].</p>
    Fórmula:C27H30N4O2S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:506.68
  • Piperidine-4-sulfonic acid

    CAS:
    <p>Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].</p>
    Fórmula:C5H11NO3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:165.21
  • P2X3-IN-1

    CAS:
    <p>P2X3-IN-1 (example 7) is a P2X3 receptor inhibitor suitable for research on neurogenic diseases [1].</p>
    Fórmula:C22H21FN8O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:464.45
  • VU0029251

    CAS:
    <p>VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.</p>
    Fórmula:C10H11N3S2
    Forma y color:Solid
    Peso molecular:237.34
  • 5-HT2C agonist-3

    CAS:
    <p>5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-induced</p>
    Fórmula:C19H23ClFNO2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:351.84
  • FPTQ

    CAS:
    <p>FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1].</p>
    Fórmula:C17H12FN5
    Pureza:99.68% - 99.88%
    Forma y color:Solid
    Peso molecular:305.31
  • Pregnanolone sulfate (pyridinium)

    CAS:
    <p>Pregnanolone sulfate pyridinium, an endogenous neurosteroid, inhibits NMDA receptors and exhibits neuroprotective properties [1].</p>
    Fórmula:C26H39NO5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:477.66
  • (S)-Bexicaserin

    CAS:
    <p>(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].</p>
    Fórmula:C15H19F2N3O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:295.33
  • 5-HT2A receptor agonist-3

    CAS:
    <p>5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.</p>
    Fórmula:C21H26BrNO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:420.34
  • AAK1-IN-3

    CAS:
    <p>AAK1-IN-3: Brain-penetrant AAK1 inhibitor for neuropathic pain research; IC50=11 nM.</p>
    Fórmula:C20H20N4
    Forma y color:Solid
    Peso molecular:316.4
  • (+)-Bicuculline methiodide

    CAS:
    <p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>
    Fórmula:C21H20INO6
    Pureza:99.24%
    Forma y color:Solid
    Peso molecular:509.29
  • BMS 433796

    CAS:
    <p>BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.</p>
    Fórmula:C21H20F2N4O4
    Pureza:99.17%
    Forma y color:Solid
    Peso molecular:430.4
  • 5-HT3 antagonist 1

    CAS:
    <p>5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.</p>
    Fórmula:C22H27N5O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:377.48
  • Fosthiazate

    CAS:
    <p>Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., by</p>
    Fórmula:C9H18NO3PS2
    Pureza:97.78%
    Forma y color:Solid
    Peso molecular:283.35
  • BMS-933043

    CAS:
    <p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) &amp; human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>
    Fórmula:C16H19N7O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:325.37
  • UNC9994 hydrochloride

    CAS:
    <p>UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.</p>
    Fórmula:C21H23Cl3N2OS
    Forma y color:Solid
    Peso molecular:457.84
  • R-96544

    CAS:
    <p>R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].</p>
    Fórmula:C22H30ClNO3
    Forma y color:Solid
    Peso molecular:391.93
  • PHP 501 trifluoroacetate

    CAS:
    <p>GABAA antagonist</p>
    Fórmula:C20H21N3O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:319.4
  • MK-8768

    CAS:
    <p>MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by</p>
    Fórmula:C21H22F3N5O2
    Forma y color:Solid
    Peso molecular:433.43
  • Atabecestat

    CAS:
    <p>Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.</p>
    Fórmula:C18H14FN5OS
    Pureza:99.21% - 99.77%
    Forma y color:Solid
    Peso molecular:367.4
  • Tematropium

    CAS:
    <p>Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.</p>
    Fórmula:C21H31NO8S
    Pureza:99.89%
    Forma y color:Solid
    Peso molecular:457.54
  • Philanthotoxin 74 dihydrochloride

    CAS:
    <p>Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.</p>
    Fórmula:C24H44Cl2N4O3
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:507.54
  • AMPA receptor antagonist-3

    CAS:
    <p>AMPA receptor antagonist-3 is an AMPA receptor antagonist.</p>
    Fórmula:C20H19N5O2S
    Pureza:99.79%
    Forma y color:Solid
    Peso molecular:393.46
  • WAY-607695

    CAS:
    <p>WAY-607695 is a potential 5-HT1A receptor agonist.</p>
    Fórmula:C13H12FNO2
    Pureza:99.82%
    Forma y color:Solid
    Peso molecular:233.24
  • AMPA receptor modulator-1

    CAS:
    <p>AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.</p>
    Fórmula:C16H11ClF3NO2
    Pureza:99.93%
    Forma y color:Solid
    Peso molecular:341.71
  • Didesmethyl cariprazine

    CAS:
    <p>Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.</p>
    Fórmula:C19H28Cl2N4O
    Pureza:99.52%
    Forma y color:Solid
    Peso molecular:399.36
  • TZ3O

    CAS:
    <p>TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.</p>
    Fórmula:C18H13NO4S
    Pureza:99.84%
    Forma y color:Solid
    Peso molecular:339.37
  • R-(+)-EU-1180-453

    CAS:
    <p>R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.</p>
    Fórmula:C22H21FN2O3
    Pureza:99.63%
    Forma y color:Solid
    Peso molecular:380.41
  • Osemozotan HCl

    CAS:
    <p>Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.</p>
    Fórmula:C19H22ClNO5
    Pureza:98.87% - 99.63%
    Forma y color:Solid
    Peso molecular:379.84
  • CGP 78608 hydrochloride

    CAS:
    <p>CGP 78608 hydrochloride: NMDA receptor antagonist (IC50=6 nM), anticonvulsant, enhances GluN1/GluN3A currents (EC50=26.3 nM).</p>
    Fórmula:C11H14BrClN3O5P
    Pureza:99.85%
    Forma y color:Solid
    Peso molecular:414.58
  • VU6004909

    CAS:
    <p>VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.</p>
    Fórmula:C21H15FN2O4
    Pureza:96.68% - 98.44%
    Forma y color:Solid
    Peso molecular:378.35
  • JNJ-42253432

    CAS:
    <p>JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels</p>
    Fórmula:C28H38N4O
    Pureza:99.98%
    Forma y color:Solid
    Peso molecular:446.63
  • Dalzanemdor

    CAS:
    <p>Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive</p>
    Fórmula:C27H43F3O2
    Pureza:98.2% - >99.99%
    Forma y color:Solid
    Peso molecular:456.62
  • SB 216641 hydrochloride

    CAS:
    <p>SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.</p>
    Fórmula:C28H31ClN4O4
    Pureza:98.06% - 99.23%
    Forma y color:Solid
    Peso molecular:523.02
  • γ-Secretase-IN-1

    CAS:
    <p>γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.</p>
    Fórmula:C27H24F2N4O3
    Pureza:99.56%
    Forma y color:Solid
    Peso molecular:490.5
  • Rislenemdaz

    CAS:
    <p>Rislenemdaz (CERC-301) (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B).</p>
    Fórmula:C19H23FN4O2
    Pureza:98.18%
    Forma y color:Solid
    Peso molecular:358.41
  • Gossypolone

    CAS:
    <p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>
    Fórmula:C30H26O10
    Pureza:96.66%
    Forma y color:Solid
    Peso molecular:546.52
  • BuChE-IN-TM-10

    CAS:
    <p>TM-10: Potent BuChE inhibitor, IC50 8.9 nM, disaggregates Aβ, antioxidant, BBB penetrant, may treat Alzheimer's.</p>
    Fórmula:C32H38N2O3
    Pureza:99.54%
    Forma y color:Solid
    Peso molecular:498.66
  • BMS-986176

    CAS:
    <p>AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).</p>
    Fórmula:C19H23F4N3O
    Pureza:98.58% - 98.7%
    Forma y color:Solid
    Peso molecular:385.4
  • PXS-5153A

    CAS:
    <p>PXS-5153A rapidly inhibits lysyl oxidase 2/3 enzymes, blocks activity in 15 mins, and reduces fibrosis.</p>
    Fórmula:C20H25Cl2FN4O2S
    Pureza:99.58%
    Forma y color:Solid
    Peso molecular:475.41
  • Lumateperone

    CAS:
    <p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>
    Fórmula:C24H28FN3O
    Pureza:99.68% - 99.91%
    Forma y color:Solid
    Peso molecular:393.5
  • PXS-5120A

    CAS:
    <p>PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.</p>
    Fórmula:C22H25ClFN3O4S
    Pureza:97.02%
    Forma y color:Solid
    Peso molecular:481.97
  • SB-616234-A

    CAS:
    <p>SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.</p>
    Fórmula:C32H36ClN5O3
    Pureza:99.72%
    Forma y color:Solid
    Peso molecular:574.11
  • MDR-1339

    CAS:
    <p>MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.</p>
    Fórmula:C20H22O4
    Pureza:98.57%
    Forma y color:Solid
    Peso molecular:326.39
  • (S)-YNT-3708

    CAS:
    <p>(S)-YNT-3708 is the S-isomer of YNT-3708, demonstrating relatively low activity against OX1R and OX2R receptors, with EC50 values of 3595 nM and 1661 nM, respectively.</p>
    Fórmula:C35H36N4O6S
    Forma y color:Solid
    Peso molecular:640.749
  • Buntanetap L-Tartrate

    CAS:
    <p>Buntanetap (L-Tartrate) functions as an oral small molecule inhibitor targeting multiple neurotoxic proteins. It decreases the production of amyloid precursor protein (APP) by inhibiting the translation of its mRNA [1].</p>
    Fórmula:C24H29N3O8
    Forma y color:Solid
    Peso molecular:487.50
  • AChE-IN-79


    <p>AChE-IN-79 (compound 3i) is an acetylcholinesterase inhibitor with an IC50 of 2.7 µM, suitable for studies related to Alzheimer's disease.</p>
    Fórmula:C29H27NO6S
    Forma y color:Solid
    Peso molecular:517.59
  • AChE/BChE-IN-24

    CAS:
    <p>AChE/BChE-IN-24 (compound 5k) functions as a neuroprotective agent by inhibiting acetylcholinesterase. It targets both AChE and BChE, demonstrating IC50 values of 16.38 μM and 10.44 μM, respectively.</p>
    Fórmula:C20H21N3
    Forma y color:Solid
    Peso molecular:303.4
  • CL-13


    <p>CL-13 is an inhibitor of butyrylcholinesterase (BChE), exhibiting an IC50 of 1.15 μM and a selectivity index (SI) of 9.2 for acetylcholinesterase. It demonstrates antioxidative activity in SH-SY5Y cells with a DPPHEC50 of 47.01 μM and has the capacity to chelate metals involved in Aβ aggregation and/or oxidative stress, showing no neurotoxicity at concentrations up to 50 μM. CL-13 can also reverse scopolamine-induced cognitive impairments without affecting motor abilities in mice.</p>
    Fórmula:C29H32N4OS
    Forma y color:Solid
    Peso molecular:484.66
  • AGH-107

    CAS:
    <p>AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.</p>
    Fórmula:C13H12IN3
    Forma y color:Solid
    Peso molecular:337.16
  • Tipindole

    CAS:
    <p>Tipindole is a serotonin antagonist utilized in research related to depression.</p>
    Fórmula:C16H20N2O2S
    Forma y color:Solid
    Peso molecular:304.41
  • Amyloid-β-IN-3

    CAS:
    <p>Amyloid-β-IN-3 (EX.113) is a selective inhibitor of γ-secretase. It demonstrates inhibitory activity on Aβ42 secretion in H4 cells, with an EC50 value of 148 nM. By modulating the catalytic activity of γ-secretase, Amyloid-β-IN-3 decreases Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. It holds potential for Alzheimer's disease (AD) research.</p>
    Fórmula:C22H21F2N3O2
    Forma y color:Solid
    Peso molecular:397.42
  • AChE-IN-8


    <p>AChE-IN-8 (Compound 19), potent acetylcholinesterase blocker; IC50 = 1.95 μM; potential Alzheimer's treatment.</p>
    Fórmula:C20H22N4O2S
    Forma y color:Solid
    Peso molecular:382.48
  • Zanapezil fumarate

    CAS:
    <p>Zanapezil is an acetylcholinesterase (AChE) inhibitor. Zanapezil increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.</p>
    Fórmula:C29H36N2O5
    Forma y color:Solid
    Peso molecular:492.61
  • Monoamine Oxidase B inhibitor 2


    <p>MAO-B inhibitor 2: potent, reversible, oral, selective (IC50=1.33 nM), BBB-penetrant, with anti-oxidant and anti-inflammatory effects for Parkinson's study.</p>
    Fórmula:C19H19FO3
    Forma y color:Solid
    Peso molecular:314.35
  • K027


    <p>K027 is a potent organophosphate (OP) inhibitor of acetylcholinesterase (AChE) reactivation. k027 can be used to study Alzheimer's disease.</p>
    Fórmula:C15H18Br2N4O2
    Forma y color:Solid
    Peso molecular:446.14
  • PXS-5153A monohydrochloride

    CAS:
    <p>PXS-5153A is an oral, fast-acting LOXL2/3 inhibitor with IC50 &lt;40 nM for LOXL2 and 63 nM for LOXL3, potentially treating fibrosis.</p>
    Fórmula:C20H25Cl2FN4O2S
    Pureza:98%
    Forma y color:Odour Solid
    Peso molecular:475.41
  • LRRK2-IN-2

    CAS:
    <p>LRRK2-IN-2: selective, potent LRRK2 inhibitor, IC50 of 0.6 nM, oral, crosses blood-brain barrier, for Parkinson's research.</p>
    Fórmula:C23H23Cl2F3N6O2
    Forma y color:Solid
    Peso molecular:543.37
  • Befiradol hydrochloride

    CAS:
    <p>Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.</p>
    Fórmula:C20H23Cl2F2N3O
    Pureza:99.1%
    Forma y color:Solid
    Peso molecular:430.32
  • γ-Secretase modulator 11 hydrochloride

    CAS:
    <p>γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM).</p>
    Fórmula:C28H23ClF2N4O2
    Forma y color:Solid
    Peso molecular:520.96
  • PF-06648671

    CAS:
    <p>PF-06648671 is a γ-secretase modulator for the treatment of neurodegenerative and/or neurological disorders.</p>
    Fórmula:C25H23ClF4N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:538.92
  • cSPM


    <p>cSPM (Cyclic spermine) is an Aβ42 inhibitor. cSPM inhibits the aggregation of three different peptides, Aβ42, tryptophan and insulin, and reduces cytotoxicity.</p>
    Fórmula:C27H57N7
    Forma y color:Solid
    Peso molecular:479.79
  • ChE/Aβ1-42-IN-1


    <p>ChE/Aβ1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Aβ 1-42 with excellent BBB permeability.</p>
    Fórmula:C19H24N2O3
    Forma y color:Solid
    Peso molecular:328.41
  • Carlina oxide

    CAS:
    <p>Carlina oxide is both an AChE inhibitor and an antioxidant, effective in eliminating mosquito larvae (LC50=1.39 μg/mL). Furthermore, Carlina oxide exhibits cytotoxicity in vertebrate cells, human dermis, and HCT116 and MDA-MB231 cell lines.</p>
    Fórmula:C13H10O
    Forma y color:Solid
    Peso molecular:182.22
  • MADAM

    CAS:
    <p>MADAM demonstrates high affinity and selectivity for 5-HTT, with a Ki value of 1.6 nM. It is utilized as a PET radiotracer for visualizing serotonin transporters.</p>
    Fórmula:C16H20N2S
    Forma y color:Solid
    Peso molecular:272.408
  • hAChE-IN-10

    CAS:
    <p>hAChE-IN-10 (Compound ET11) is an inhibitor of human acetylcholinesterase (AChE) with an IC50 of 6.34 nM. This compound is capable of scavenging free radicals and exhibits antioxidant activity. Additionally, hAChE-IN-10 demonstrates metal-chelating properties, inhibiting Cu2+-induced Aβ1-42 aggregation, reducing amyloid plaque formation, and offering neuroprotective effects. It also ameliorates cognitive impairment in mice induced by Scopolamine.</p>
    Fórmula:C25H24ClFN6O2
    Forma y color:Solid
    Peso molecular:494.948
  • Ro4368554

    CAS:
    <p>Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.</p>
    Fórmula:C19H21N3O2S
    Forma y color:Solid
    Peso molecular:355.454
  • U92016A hydrochloride

    CAS:
    <p>U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.</p>
    Fórmula:C19H26ClN3
    Forma y color:Solid
    Peso molecular:331.89
  • 5-HT1A modulator 4

    CAS:
    <p>5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.</p>
    Fórmula:C9H14N4
    Forma y color:Solid
    Peso molecular:178.234
  • S-8510 phosphate

    CAS:
    <p>S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).</p>
    Fórmula:C12H13N4O6P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:340.23