Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(1.025 productos)
- ACK(1 productos)
- AChR(647 productos)
- ATP Citrato Liasa(17 productos)
- Receptor adrenérgico(3.025 productos)
- BACE(37 productos)
- Beta amiloide(230 productos)
- CAMK(73 productos)
- Inhibidores de ciclooxigenasa (COX)(602 productos)
- Receptor de dopamina(445 productos)
- Receptor GABA(373 productos)
- Gamma-secretasa(62 productos)
- GluR(265 productos)
- GlyT(26 productos)
- Receptor de histamina(385 productos)
- LRRK2(43 productos)
- Receptor de melatonina(26 productos)
- NMDAR(10 productos)
- Receptor de OX(41 productos)
- Receptor de opioides(327 productos)
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Se han encontrado 5639 productos de "Neurociencia"
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CP-122288
CAS:CP-122288: potent, selective 5-HT1B/D/F agonist; inhibits plasma protein extravasation, neurogenic inflammation.Fórmula:C16H23N3O2SPureza:98%Forma y color:SolidPeso molecular:321.44MAO-IN-3
CAS:MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B,Fórmula:C42H54N4O4Pureza:98%Forma y color:SolidPeso molecular:678.93β-Hydroxy-lup-20(29)-en-16-one
CAS:3β-Hydroxy-lup-20(29)-en-16-one (compound 9) serves as a dual inhibitor of both AChE and BChE, displaying a preference for BChE with an IC50 of 28.9 μM [1].Fórmula:C30H48O2Forma y color:SolidPeso molecular:440.7SB 258719
CAS:SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.Fórmula:C18H30N2O2SPureza:99.73%Forma y color:SolidPeso molecular:338.51Ref: TM-T12855
2mg34,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg85,00€25mg155,00€50mg240,00€100mg355,00€200mg502,00€Benoxaprofen
CAS:Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.Fórmula:C16H12ClNO3Pureza:98.87%Forma y color:SolidPeso molecular:301.72Ref: TM-T19679
1mg202,00€1mL*10mM (DMSO)469,00€5mg472,00€10mg707,00€25mg1.035,00€50mg1.311,00€100mg1.663,00€rTRD01
CAS:rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269.Fórmula:C18H21FN4O2Pureza:99.44%Forma y color:SolidPeso molecular:344.38AAK1-IN-4
CAS:AAK1-IN-4 selectively inhibits AAK1 with IC50 of 4.6 nM; penetrates CNS, oral bioactive, potential for studying neuropathic pain.Fórmula:C20H28N4O3Forma y color:SolidPeso molecular:372.46JNJ-46281222
CAS:JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.Fórmula:C23H25F3N4Forma y color:SolidPeso molecular:414.47SDZ-216525
CAS:SDZ-216525, a 5-HT1A receptor antagonist, inhibits the tracheal contractions induced both by NKA (10 nM-3 microM) and 5-HT (10 nM-10 microM) (n=4-10).Fórmula:C25H28N4O5SForma y color:SolidPeso molecular:496.58Flesinoxan
CAS:Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).Fórmula:C22H26FN3O4Forma y color:SolidPeso molecular:415.46QM-FN-SO3
CAS:QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].Fórmula:C29H25N4NaO3S2Forma y color:SolidPeso molecular:564.656,2'-Dihydroxyflavone
CAS:6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.Fórmula:C15H10O4Pureza:99.44% - 99.67%Forma y color:SolidPeso molecular:254.24L-AP4
CAS:L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).Fórmula:C4H10NO5PPureza:98%Forma y color:White To Off-White Crystalline PowderPeso molecular:183.1(R)-4-Amino-3-hydroxybutyric Acid
CAS:(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.Fórmula:C4H9NO3Forma y color:SolidPeso molecular:119.12LY2033298
CAS:LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.Fórmula:C13H14ClN3O2SPureza:98.78%Forma y color:SolidPeso molecular:311.79NO-711ME
CAS:NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.Fórmula:C22H24N2O3Pureza:99.54%Forma y color:SolidPeso molecular:364.44Ref: TM-T24540
1mg64,00€5mg129,00€1mL*10mM (DMSO)138,00€10mg188,00€25mg299,00€50mg427,00€100mg575,00€200mg767,00€CGP 54626 hydrochloride
CAS:CGP 54626 hydrochloride is a GABAB receptor antagonist.Fórmula:C18H29Cl3NO3PPureza:98%Forma y color:SolidPeso molecular:444.765-HT2C agonist-3 free base
CAS:5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-Fórmula:C19H22FNO2Pureza:98%Forma y color:SolidPeso molecular:315.38L 663581
CAS:L 663581 is the benzodiazepine receptor partial agonist.Fórmula:C17H16ClN5O2Pureza:98%Forma y color:SolidPeso molecular:357.795-HT2 agonist-1 free base
CAS:Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,Fórmula:C19H22N2O2Pureza:98%Forma y color:SolidPeso molecular:310.39CGP36216 hydrochloride
CAS:CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].Fórmula:C5H15ClNO2PForma y color:SolidPeso molecular:187.6(±)-Fabesetron hydrochloride
CAS:FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.Fórmula:C18H20ClN3OPureza:98%Forma y color:SolidPeso molecular:329.82Dothiepin
CAS:Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancingFórmula:C19H21NSPureza:98%Forma y color:SolidPeso molecular:295.445-HT2C agonist-3
CAS:5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-inducedFórmula:C19H23ClFNO2Pureza:98%Forma y color:SolidPeso molecular:351.84DU-125530
CAS:DU-125530 is a 5-HT1A receptor antagonist.Fórmula:C23H26ClN3O5SForma y color:SolidPeso molecular:491.99BT-GSI
BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.Fórmula:C26H46BrN5O10P2Forma y color:SolidPeso molecular:730.52(S)-Bexicaserin
CAS:(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].Fórmula:C15H19F2N3OPureza:98%Forma y color:SolidPeso molecular:295.33BChE-IN-20
CAS:BChE-IN-20 (compound 7c) is a potent, selective inhibitor of BChE, demonstrating IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE.Fórmula:C27H39N5O2Forma y color:SolidPeso molecular:465.63QR-0217
CAS:QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Fórmula:C19H13NO3Forma y color:SolidPeso molecular:303.315-HT2A receptor agonist-3
CAS:5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.Fórmula:C21H26BrNO3Pureza:98%Forma y color:SolidPeso molecular:420.34MGS-0039
CAS:MGS-0039: Group II mGluR2/3 antagonist, non-serotonergic antidepressant-like effect, AMPA involvement, regulates dopamine in NAc.Fórmula:C15H14Cl2FNO5Pureza:98%Forma y color:SolidPeso molecular:378.18Yhhu-3792 hydrochloride
CAS:Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].Fórmula:C24H25ClN4O2Forma y color:SolidPeso molecular:436.93BACE1-IN-13
CAS:BACE1-IN-13 (Compound 36), an orally active inhibitor of BACE1, exhibits high potency with an IC50 of 2.9 nM and demonstrates greater efficacy in hAβ42 cells (Fórmula:C20H17FN8O2Pureza:98%Forma y color:SolidPeso molecular:420.4ABT-418 hydrochloride
CAS:ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.Fórmula:C9H15ClN2OForma y color:SolidPeso molecular:202.68GYKI-46903 HCl
CAS:GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.Fórmula:C17H21ClFNO2Forma y color:SolidPeso molecular:325.81LY320954
CAS:LY320954 is an antagonist of 5-HT2A receptor.Fórmula:C21H26N4O3Pureza:98%Forma y color:SolidPeso molecular:382.46NCS-382 sodium
CAS:NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological diseaseFórmula:C13H13NaO3Pureza:98%Forma y color:SolidPeso molecular:240.235-HT2A&5-HT2C agonist-1
CAS:5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.Fórmula:C14H20N2OPureza:98%Forma y color:SolidPeso molecular:232.32RAGE/SERT-IN-1
CAS:RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM andFórmula:C38H41ClN4OSForma y color:SolidPeso molecular:637.28Muscarine tosylate
CAS:Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].Fórmula:C16H27NO5SForma y color:SolidPeso molecular:345.453-Bromocytisine
CAS:3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).Fórmula:C11H13BrN2OPureza:99.974%Forma y color:SolidPeso molecular:269.14Ref: TM-T10108
1mg95,00€1mL*10mM (DMSO)178,00€5mg202,00€10mg293,00€25mg494,00€50mg710,00€100mg973,00€200mg1.305,00€Facinicline hydrochloride
CAS:Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).Fórmula:C15H19ClN4OPureza:98.70%Forma y color:SolidPeso molecular:306.79CGP 64213
CAS:CGP 64213 is a GABAb receptor agonist.Fórmula:C26H36IN2O7PPureza:98%Forma y color:SolidPeso molecular:646.45FPPQ
CAS:FPPQ blocks 5-HT3 and 5-HT6 receptors (Ki: 0.9 & 3 nM) and may improve psychosis and cognition.Fórmula:C21H19FN4O2SForma y color:SolidPeso molecular:410.46Befiradol
CAS:Befiradol (NLX-112) is an agonist of 5-HT1A receptor.Fórmula:C20H22ClF2N3OForma y color:SolidPeso molecular:393.86mAChR antagonist 1
CAS:Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,Fórmula:C19H22N2O2Forma y color:SolidPeso molecular:310.39AChE-IN-19
CAS:AChE-IN-19: strong AChE blocker (IC50: 0.56 μM), hinders Aβ clumps, neuro-protective, non-toxic to SH-SY5Y, for Alzheimer's research.Fórmula:C30H33NO7Forma y color:SolidPeso molecular:519.59(2R,4R)-APDC
CAS:(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.Fórmula:C6H10N2O4Pureza:98%Forma y color:SolidPeso molecular:174.15Adipiplon
CAS:Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.Fórmula:C18H18FN7Forma y color:SolidPeso molecular:351.38NAS181
CAS:rat 5-HT1B receptor antagonistFórmula:C21H34N2O10S2Pureza:98%Forma y color:SolidPeso molecular:538.63ADX71441
CAS:ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.Fórmula:C19H15ClF2N4O4Forma y color:SolidPeso molecular:436.85-HT3 antagonist 1
CAS:5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.Fórmula:C22H27N5OPureza:98%Forma y color:SolidPeso molecular:377.48(1α,1'S,4β)-Lanabecestat
CAS:(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay),Fórmula:C26H28N4OForma y color:SolidPeso molecular:412.53ASS234
CAS:ASS234 is a multi-target propylamine used in the treatment of Alzheimer's disease.Fórmula:C29H37N3OForma y color:SolidPeso molecular:443.62Fosthiazate
CAS:Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., byFórmula:C9H18NO3PS2Pureza:97.78%Forma y color:SolidPeso molecular:283.35PTAC oxalate
CAS:muscarinic receptor ligandFórmula:C14H21N3O4S2Pureza:98%Forma y color:SolidPeso molecular:359.46LY108742
CAS:LY108742 is an antagonist of 5-HT2.Fórmula:C21H28N2O3Pureza:98%Forma y color:SolidPeso molecular:356.46Gepirone
CAS:Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Fórmula:C19H29N5O2Pureza:99.35% - 99.89%Forma y color:SolidPeso molecular:359.47BACE1-IN-1
CAS:BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).Fórmula:C18H14F3N5O2Pureza:98%Forma y color:SolidPeso molecular:389.33Physostigmine hemisulfate
CAS:cholinesterase inhibitorFórmula:C15H21N302H204SPureza:98%Forma y color:SolidPeso molecular:324.39Abaperidone
CAS:Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.Fórmula:C25H25FN2O5Pureza:99.77%Forma y color:SolidPeso molecular:452.47GR 127935 hydrochloride
CAS:5-HT1B/1D receptor antagonistFórmula:C29H32ClN5O3Pureza:98%Forma y color:SolidPeso molecular:534.05ASP8302
CAS:ASP8302 is an allosteric potentiator of the muscarinic M3 receptor. It enhances urination efficiency and reduces residual urine volume in two rat models of voiding dysfunction. ASP8302 is useful for investigating diseases associated with bladder dysfunction.Fórmula:C26H32ClN7O3S2Forma y color:SolidPeso molecular:590.16Nemonapride
CAS:Nemonapride is a dopamine D2-like receptor antagonist.Fórmula:C21H26ClN3O2Pureza:98%Forma y color:SolidPeso molecular:387.9CGP-54626 free base
CAS:CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).Fórmula:C18H28Cl2NO3PPureza:98%Forma y color:SolidPeso molecular:408.3(S)-Renzapride
(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.Fórmula:C16H22ClN3O2Forma y color:SolidPeso molecular:323.82MAO-B-IN-1
CAS:MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.Fórmula:C16H14F3N3O2SPureza:98%Forma y color:SolidPeso molecular:369.36BMS-932481
CAS:BMS-932481 is a γ-secretase modulator.Fórmula:C24H24FN7OForma y color:SolidPeso molecular:445.49Wf-516
CAS:Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressantFórmula:C25H25Cl2N3O4Pureza:98%Forma y color:SolidPeso molecular:502.39Anti-amyloid agent-1
CAS:Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].Fórmula:C21H17F3N2O3Forma y color:SolidPeso molecular:402.37VU 0255035
CAS:VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.
Fórmula:C18H20N6O3S2Pureza:98.09% - 98.1%Forma y color:SolidPeso molecular:432.525-HT2 agonist-1
CAS:Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.Fórmula:C19H23ClN2O2Pureza:98%Forma y color:SolidPeso molecular:346.85β-Secretase Inhibitor IV
CAS:β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).Fórmula:C31H38N4O5SPureza:98%Forma y color:SolidPeso molecular:578.72R-96544
CAS:R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].Fórmula:C22H30ClNO3Forma y color:SolidPeso molecular:391.93L-822179
CAS:L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.Fórmula:C17H14N8O2Pureza:98.5% - 99.61%Forma y color:SolidPeso molecular:362.35MIN-117
CAS:MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.Fórmula:C25H26Cl3N3O4Pureza:98%Forma y color:SolidPeso molecular:538.85Biphenylindanone A
CAS:Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.Fórmula:C30H30O4Pureza:98%Forma y color:SolidPeso molecular:454.56Octahydroaminoacridine succinate
CAS:Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.Fórmula:C17H24N2O4Pureza:99.91%Forma y color:SolidPeso molecular:320.38MTPG
CAS:Group II/group III metabotropic glutamate receptor antagonistFórmula:C10H11N5O2Pureza:98%Forma y color:SolidPeso molecular:233.23rel-HDMP 28 hydrochloride
CAS:Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].Fórmula:C18H22ClNO2Forma y color:SolidPeso molecular:319.83LY-426965
CAS:LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.Fórmula:C28H38N2O2Forma y color:SolidPeso molecular:434.61mGluR5 antagonist-1
CAS:mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].Fórmula:C23H18N4O2Forma y color:SolidPeso molecular:382.41N-Demethyl MK-6884
CAS:N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.Fórmula:C24H23N5OForma y color:SolidPeso molecular:397.47GABAA receptor agent 2 TFA
CAS:Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.Fórmula:C22H22F3N3O3Forma y color:SolidPeso molecular:433.42LY3202626
CAS:LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.Fórmula:C22H20F2N8O2SPureza:98%Forma y color:SolidPeso molecular:498.51Lanabecestat HCl
CAS:Lanabecestat (AZD3293/LY3314814) is a potent oral BACE1 inhibitor that crosses the BBB and reduces Aβ levels.Fórmula:C26H29ClN4OForma y color:SolidPeso molecular:448.995Robalzotan
CAS:Robalzotan is a selective 5-HT1A receptor antagonist.Fórmula:C18H23FN2O2Pureza:98%Forma y color:SolidPeso molecular:318.39Frovatriptan
CAS:Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.Fórmula:C14H17N3OPureza:100%Forma y color:SolidPeso molecular:243.3Brasofensine
CAS:Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.Fórmula:C16H20Cl2N2OForma y color:SolidPeso molecular:327.25Brilaroxazine
CAS:Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.Fórmula:C22H25Cl2N3O3Pureza:99.36%Forma y color:SolidPeso molecular:450.36Ref: TM-T14782
1mg100,00€5mg236,00€1mL*10mM (DMSO)268,00€10mg385,00€25mg663,00€50mg954,00€100mg1.305,00€200mg1.738,00€Butriptyline
CAS:Butriptyline (Butriptylene), a tricyclic antidepressant, is effective when administered orally [1].Fórmula:C21H27NForma y color:SolidPeso molecular:293.45CGP 55845 hydrochloride
CAS:CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].Fórmula:C18H23Cl3NO3PForma y color:SolidPeso molecular:438.71Hydroxy Varenicline
CAS:Hydroxy varenicline, a metabolite of the nicotinic acetylcholine receptor (nAChR) agonist varenicline, functions within the biochemical pathway by interacting with nAChR sites.Fórmula:C13H13N3OForma y color:SolidPeso molecular:227.267NAS-181
CAS:NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.Fórmula:C20H30N2O7SForma y color:SolidPeso molecular:442.53PZ-II-029
CAS:PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.Fórmula:C18H15N3O3Pureza:99.79%Forma y color:SolidPeso molecular:321.33Ref: TM-T28479
1mg50,00€5mg105,00€10mg167,00€1mL*10mM (DMSO)192,00€25mg289,00€50mg447,00€100mg685,00€500mg1.378,00€AChE-IN-44
CAS:AChE-IN-44 (Compound Tap4), an AChE inhibitor, is convertible into its thiazole salt form known as Tat2 [1].Fórmula:C31H38ClN3OS2Forma y color:SolidPeso molecular:568.24Afizagabar
CAS:Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.Fórmula:C19H12FN3O2SForma y color:SolidPeso molecular:365.38(+)-Bicuculline methiodide
CAS:(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.Fórmula:C21H20INO6Pureza:99.24%Forma y color:SolidPeso molecular:509.29mGAT-IN-1
CAS:mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).Fórmula:C28H34ClN3O2S2Forma y color:SolidPeso molecular:544.17Brasofensine sulfate
CAS:Brasofensine sulfate is a dopamine reuptake inhibitor.Fórmula:C16H22Cl2N2O5SForma y color:SolidPeso molecular:425.33
