Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(1.025 productos)
- ACK(1 productos)
- AChR(647 productos)
- ATP Citrato Liasa(17 productos)
- Receptor adrenérgico(3.023 productos)
- BACE(37 productos)
- Beta amiloide(230 productos)
- CAMK(73 productos)
- Inhibidores de ciclooxigenasa (COX)(602 productos)
- Receptor de dopamina(445 productos)
- Receptor GABA(373 productos)
- Gamma-secretasa(62 productos)
- GluR(265 productos)
- GlyT(26 productos)
- Receptor de histamina(385 productos)
- LRRK2(43 productos)
- Receptor de melatonina(26 productos)
- NMDAR(10 productos)
- Receptor de OX(41 productos)
- Receptor de opioides(327 productos)
Mostrar 12 subcategorías más
Se han encontrado 5637 productos de "Neurociencia"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Flesinoxan
CAS:Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).Fórmula:C22H26FN3O4Forma y color:SolidPeso molecular:415.461-Carboxycyclohexaneacetic Acid
CAS:1-Carboxycyclohexaneacetic acid may be present as a potential impurity in commercial gabapentin, an antiepileptic drug. Furthermore, it serves as a precursor for synthesizing antagonists targeting the serotonin (5-HT) receptor subtype 5-HT2A.Fórmula:C9H14O4Forma y color:SolidPeso molecular:186.207RAGE/SERT-IN-1
CAS:RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM andFórmula:C38H41ClN4OSForma y color:SolidPeso molecular:637.28LY-426965
CAS:LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.Fórmula:C28H38N2O2Forma y color:SolidPeso molecular:434.61mGluR5 antagonist-1
CAS:mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].Fórmula:C23H18N4O2Forma y color:SolidPeso molecular:382.41Gentisein
CAS:Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7Fórmula:C13H8O5Pureza:96.89%Forma y color:SolidPeso molecular:244.2BACE1-IN-10
CAS:BACE1-IN-10 is a potent inhibitor of BACE1, demonstrating sub-micromolar activity against recombinant BACE1 (rBACE1) [1].Fórmula:C33H49N5O8SPureza:98%Forma y color:SolidPeso molecular:675.84Fosthiazate
CAS:Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., byFórmula:C9H18NO3PS2Pureza:97.78%Forma y color:SolidPeso molecular:283.352-Methyl-5-HT
CAS:2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Fórmula:C11H14N2OPureza:97.18%Forma y color:SolidPeso molecular:190.24Ref: TM-T10075
5mg48,00€1mL*10mM (DMSO)50,00€10mg84,00€25mg177,00€50mg334,00€100mg500,00€500mg1.099,00€L-822179
CAS:L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.Fórmula:C17H14N8O2Pureza:98.5% - 99.61%Forma y color:SolidPeso molecular:362.35rTRD01
CAS:rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269.Fórmula:C18H21FN4O2Pureza:99.44%Forma y color:SolidPeso molecular:344.38BACE1-IN-1
CAS:BACE1-IN-1 is a high brain penetrant BACE1 inhibitor (IC50s: 32 and 47 nM for human BACE1 and BACE2).Fórmula:C18H14F3N5O2Pureza:98%Forma y color:SolidPeso molecular:389.33CGP 55845
CAS:CGP 55845: potent, selective GABAB blocker, IC50=5 nM, hinders agonist binding, reduces GABA/glutamate release.Fórmula:C18H22Cl2NO3PForma y color:SolidPeso molecular:402.25JNJ-46281222
CAS:JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.Fórmula:C23H25F3N4Forma y color:SolidPeso molecular:414.47RPC425 free base
CAS:RPC425 is a noncompetitive inhibitors of the Betaine-γ-Aminobutyric Acid Transporter 1 (BGT1).Fórmula:C22H27NO2S2Pureza:98%Forma y color:SolidPeso molecular:401.59SCS
CAS:SCS is a GABAA receptor antagonist.Fórmula:C14H12N2O3Pureza:99.73%Forma y color:SolidPeso molecular:256.26Cyclophostin
CAS:Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).Fórmula:C8H11O6PPureza:98%Forma y color:SolidPeso molecular:234.14MK-8768
CAS:MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized byFórmula:C21H22F3N5O2Forma y color:SolidPeso molecular:433.43Serine Hydrolase inhibitor-21
CAS:Serine Hydrolase Inhibitor-21 (compound 8), a pyridine-based serine hydrolase inhibitor, exhibits a K i of 429 nM against BuChE, and shows promise for AlzheimerFórmula:C18H12N2O2SPureza:98%Forma y color:SolidPeso molecular:320.37GABA-IN-2
CAS:GABA-IN-2 (Compound 5), a GABA inhibitor, exhibits both larvicidal and insecticidal properties, achieving an 87% mortality rate at a concentration of 50 mg/L [1Fórmula:C12H4Cl2F6N4SeForma y color:SolidPeso molecular:468.04NO-711ME
CAS:NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.Fórmula:C22H24N2O3Pureza:99.54%Forma y color:SolidPeso molecular:364.44Ref: TM-T24540
1mg64,00€5mg129,00€1mL*10mM (DMSO)138,00€10mg188,00€25mg299,00€50mg427,00€100mg575,00€200mg767,00€mGAT-IN-1
CAS:mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).Fórmula:C28H34ClN3O2S2Forma y color:SolidPeso molecular:544.17Facinicline hydrochloride
CAS:Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).Fórmula:C15H19ClN4OPureza:98.70%Forma y color:SolidPeso molecular:306.79ADX71441
CAS:ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.Fórmula:C19H15ClF2N4O4Forma y color:SolidPeso molecular:436.8Aβ/tau aggregation-IN-3
CAS:Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functionalFórmula:C23H22N4O3Forma y color:SolidPeso molecular:402.45BACE-1 inhibitor 1
CAS:BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).Fórmula:C17H14BrF3N4O2Pureza:98%Forma y color:SolidPeso molecular:443.22Adipiplon
CAS:Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.Fórmula:C18H18FN7Forma y color:SolidPeso molecular:351.38Brasofensine
CAS:Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.Fórmula:C16H20Cl2N2OForma y color:SolidPeso molecular:327.25Nemonapride
CAS:Nemonapride is a dopamine D2-like receptor antagonist.Fórmula:C21H26ClN3O2Pureza:98%Forma y color:SolidPeso molecular:387.9AChE-IN-19
CAS:AChE-IN-19: strong AChE blocker (IC50: 0.56 μM), hinders Aβ clumps, neuro-protective, non-toxic to SH-SY5Y, for Alzheimer's research.Fórmula:C30H33NO7Forma y color:SolidPeso molecular:519.59Brasofensine sulfate
CAS:Brasofensine sulfate is a dopamine reuptake inhibitor.Fórmula:C16H22Cl2N2O5SForma y color:SolidPeso molecular:425.33FGIN-1-27
CAS:FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).Fórmula:C28H37FN2OPureza:99.86%Forma y color:SolidPeso molecular:436.6CGP 64213
CAS:CGP 64213 is a GABAb receptor agonist.Fórmula:C26H36IN2O7PPureza:98%Forma y color:SolidPeso molecular:646.455-HT2A receptor agonist-3
CAS:5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.Fórmula:C21H26BrNO3Pureza:98%Forma y color:SolidPeso molecular:420.34SB 258719
CAS:SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.Fórmula:C18H30N2O2SPureza:99.73%Forma y color:SolidPeso molecular:338.51Ref: TM-T12855
2mg34,00€5mg52,00€1mL*10mM (DMSO)58,00€10mg85,00€25mg155,00€50mg240,00€100mg355,00€200mg502,00€LY320954
CAS:LY320954 is an antagonist of 5-HT2A receptor.Fórmula:C21H26N4O3Pureza:98%Forma y color:SolidPeso molecular:382.46KBR 2822
CAS:KBR 2822 is an inhibitor of esterase.Fórmula:C9H15ClF3O3PSPureza:98%Forma y color:SolidPeso molecular:326.7VU0029251
CAS:VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.Fórmula:C10H11N3S2Forma y color:SolidPeso molecular:237.34BT-GSI
BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.Fórmula:C26H46BrN5O10P2Forma y color:SolidPeso molecular:730.52rel-HDMP 28 hydrochloride
CAS:Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].Fórmula:C18H22ClNO2Forma y color:SolidPeso molecular:319.83AAK1-IN-3
CAS:AAK1-IN-3: Brain-penetrant AAK1 inhibitor for neuropathic pain research; IC50=11 nM.Fórmula:C20H20N4Forma y color:SolidPeso molecular:316.4Robalzotan
CAS:Robalzotan is a selective 5-HT1A receptor antagonist.Fórmula:C18H23FN2O2Pureza:98%Forma y color:SolidPeso molecular:318.39AChE-IN-31
CAS:AChE-IN-31 (compound 1), a non-competitive acetylcholinesterase (AChE) inhibitor, exhibits potential for Alzheimer's disease research [1].Fórmula:C27H44Na2O9S2Forma y color:SolidPeso molecular:622.745-HT2A antagonist 1
CAS:5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.Fórmula:C26H28N4O2Pureza:98%Forma y color:SolidPeso molecular:428.53BMS-933043
CAS:BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).Fórmula:C16H19N7OPureza:98%Forma y color:SolidPeso molecular:325.37(S)-Renzapride
(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.Fórmula:C16H22ClN3O2Forma y color:SolidPeso molecular:323.825-HT2 agonist-1 free base
CAS:Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,Fórmula:C19H22N2O2Pureza:98%Forma y color:SolidPeso molecular:310.39(±)-Fabesetron hydrochloride
CAS:FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.Fórmula:C18H20ClN3OPureza:98%Forma y color:SolidPeso molecular:329.82Benoxaprofen
CAS:Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.Fórmula:C16H12ClNO3Pureza:98.87%Forma y color:SolidPeso molecular:301.72Ref: TM-T19679
1mg202,00€1mL*10mM (DMSO)469,00€5mg472,00€10mg707,00€25mg1.035,00€50mg1.311,00€100mg1.663,00€VU6012962
CAS:VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).Fórmula:C21H19F3N4O4Pureza:99.61% - 99.74%Forma y color:SolidPeso molecular:448.4Ref: TM-T13323
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg119,00€25mg225,00€50mg404,00€100mg592,00€AAK1-IN-5
CAS:AAK1-IN-5: Potent, selective AAK1 inhibitor; CNS-penetrant; oral; IC50: 1.2 nM; Ki: 0.05 nM; cell IC50: 0.5 nM. Useful in neuropathic pain research.Fórmula:C19H23F4N3OForma y color:SolidPeso molecular:385.4Abaperidone
CAS:Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.Fórmula:C25H25FN2O5Pureza:99.77%Forma y color:SolidPeso molecular:452.47Quinolactacin A1
CAS:Quinolactacin A1, a strong AChE inhibitor from Penicillium citrinum, aids Alzheimer's research.Fórmula:C16H18N2O2Forma y color:SolidPeso molecular:270.33LG 50643
CAS:LG 50643 is a muscarinic antagonist.Fórmula:C24H34INO2Pureza:98%Forma y color:SolidPeso molecular:495.44MFZ 10-7
CAS:MFZ 10-7 is anegative allosteric modulator of the mGluR5.Fórmula:C15H9FN2Pureza:99.80%Forma y color:SolidPeso molecular:236.24L 687306
CAS:L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.Fórmula:C11H15N3OForma y color:SolidPeso molecular:205.26(-)-Bicuculline methochloride
CAS:(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.
Fórmula:C21H20ClNO6Pureza:98%Forma y color:SolidPeso molecular:417.84Timepidium bromide
CAS:Timepidium bromide is an agent of anticholinergic.Fórmula:C17H22BrNOS2Pureza:98%Forma y color:SolidPeso molecular:400.4BMS-983970
CAS:BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.Fórmula:C26H26F4N4O3Forma y color:SolidPeso molecular:518.5PHP 501 trifluoroacetate
CAS:GABAA antagonistFórmula:C20H21N3OPureza:98%Forma y color:SolidPeso molecular:319.4VU0453595
CAS:VU0453595 is a M1 positive allosteric modulator (PAM).
Fórmula:C18H15FN4OPureza:99.91%Forma y color:SolidPeso molecular:322.34Des-4-fluorobenzyl Mosapride
CAS:Des-4-fluorobenzyl Mosapride, the main metabolite of mosapride, acts as a gastroprokinetic agent improving upper gastrointestinal (GI) motility by stimulating the serotonin receptor 4 (5-HT4; EC50= 74.2 nM, in guinea pig ileal longitudinal muscle myenteric plexus). It has been shown to increase colonic motility in dogs, horses, and guinea pigs in vivo. Mosapride, including this metabolite, is utilized in human and veterinary medicine to mitigate post-surgical and Parkinson's-induced constipation.Fórmula:C14H20ClN3O3Forma y color:SolidPeso molecular:313.785-HT2C agonist-3 free base
CAS:5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-Fórmula:C19H22FNO2Pureza:98%Forma y color:SolidPeso molecular:315.38Lanabecestat
CAS:Lanabecestat (AZD3293) is a BACE1 inhibitor (Ki: 0.4 nM), Lanabecestat is used in the study of neurological diseases like Alzheimer's disease.Fórmula:C26H28N4OPureza:98.55%Forma y color:SolidPeso molecular:412.53COR659
CAS:COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.Fórmula:C16H16ClNO3SPureza:99.75%Forma y color:SolidPeso molecular:337.82Ref: TM-T36520
1mg38,00€5mg86,00€1mL*10mM (DMSO)94,00€10mg123,00€25mg215,00€50mg299,00€100mg411,00€200mg560,00€TPA 023
CAS:TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).Fórmula:C20H22FN7OPureza:99.75%Forma y color:SolidPeso molecular:395.43BACE1-IN-13
CAS:BACE1-IN-13 (Compound 36), an orally active inhibitor of BACE1, exhibits high potency with an IC50 of 2.9 nM and demonstrates greater efficacy in hAβ42 cells (Fórmula:C20H17FN8O2Pureza:98%Forma y color:SolidPeso molecular:420.4AMPA receptor antagonist-3
CAS:AMPA receptor antagonist-3 is an AMPA receptor antagonist.Fórmula:C20H19N5O2SPureza:99.79%Forma y color:SolidPeso molecular:393.46Ref: TM-T61813
1mg185,00€5mg425,00€1mL*10mM (DMSO)455,00€10mg625,00€25mg938,00€50mg1.311,00€100mg1.795,00€Osemozotan HCl
CAS:Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.Fórmula:C19H22ClNO5Pureza:98.87% - 99.63%Forma y color:SolidPeso molecular:379.84Didesmethyl cariprazine
CAS:Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.Fórmula:C19H28Cl2N4OPureza:99.52%Forma y color:SolidPeso molecular:399.36γ-Secretase-IN-1
CAS:γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.Fórmula:C27H24F2N4O3Pureza:99.56%Forma y color:SolidPeso molecular:490.5Ref: TM-T3521
1mg120,00€5mg385,00€1mL*10mM (DMSO)416,00€10mg618,00€25mg1.224,00€50mg1.648,00€100mg2.232,00€R-(+)-EU-1180-453
CAS:R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.Fórmula:C22H21FN2O3Pureza:99.63%Forma y color:SolidPeso molecular:380.41VU6004909
CAS:VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.Fórmula:C21H15FN2O4Pureza:96.68% - 98.44%Forma y color:SolidPeso molecular:378.35BuChE-IN-TM-10
CAS:TM-10: Potent BuChE inhibitor, IC50 8.9 nM, disaggregates Aβ, antioxidant, BBB penetrant, may treat Alzheimer's.Fórmula:C32H38N2O3Pureza:99.54%Forma y color:SolidPeso molecular:498.66SB 216641 hydrochloride
CAS:SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.Fórmula:C28H31ClN4O4Pureza:98.06% - 99.23%Forma y color:SolidPeso molecular:523.02Atabecestat
CAS:Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.Fórmula:C18H14FN5OSPureza:99.21% - 99.77%Forma y color:SolidPeso molecular:367.4Ref: TM-T14338
1mg123,00€5mg295,00€1mL*10mM (DMSO)326,00€10mg477,00€25mg954,00€50mg1.279,00€100mg1.728,00€Tematropium
CAS:Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.Fórmula:C21H31NO8SPureza:99.89%Forma y color:SolidPeso molecular:457.54Ref: TM-T10732
1mg147,00€5mg356,00€1mL*10mM (DMSO)413,00€10mg558,00€25mg880,00€50mg1.179,00€100mg1.603,00€200mg2.152,00€TZ3O
CAS:TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.Fórmula:C18H13NO4SPureza:99.84%Forma y color:SolidPeso molecular:339.37AMPA receptor modulator-1
CAS:AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.
Fórmula:C16H11ClF3NO2Pureza:99.93%Forma y color:SolidPeso molecular:341.71WAY-607695
CAS:WAY-607695 is a potential 5-HT1A receptor agonist.Fórmula:C13H12FNO2Pureza:99.82%Forma y color:SolidPeso molecular:233.24MDR-1339
CAS:MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.Fórmula:C20H22O4Pureza:98.57%Forma y color:SolidPeso molecular:326.39PXS-5153A
CAS:PXS-5153A rapidly inhibits lysyl oxidase 2/3 enzymes, blocks activity in 15 mins, and reduces fibrosis.Fórmula:C20H25Cl2FN4O2SPureza:99.58%Forma y color:SolidPeso molecular:475.41BMS-986176
CAS:AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).
Fórmula:C19H23F4N3OPureza:98.58% - 98.7%Forma y color:SolidPeso molecular:385.4SB-616234-A
CAS:SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.Fórmula:C32H36ClN5O3Pureza:99.72%Forma y color:SolidPeso molecular:574.11Lumateperone
CAS:Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).Fórmula:C24H28FN3OPureza:99.68% - 99.91%Forma y color:SolidPeso molecular:393.5PXS-5120A
CAS:PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.Fórmula:C22H25ClFN3O4SPureza:97.02%Forma y color:SolidPeso molecular:481.97Ref: TM-T12584
1mg205,00€2mg293,00€5mg462,00€1mL*10mM (DMSO)502,00€10mg612,00€25mg893,00€50mg1.224,00€100mg1.639,00€Befiradol hydrochloride
CAS:Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.Fórmula:C20H23Cl2F2N3OPureza:99.64%Forma y color:SolidPeso molecular:430.32AChE-IN-63
CAS:AChE-IN-63 (Compound 5AD) serves as a selective inhibitor of hAChE, exhibiting an IC 50 value of 0.103 μM. Moreover, it inhibits hBChE and hBACE-1 with IC 50 values of 10 μM and 1.342 μM, respectively. AChE-IN-63 is effective in inhibiting Aβ aggregation and preventing the formation and deposition of Aβ1-42. It can effectively penetrate the blood-brain barrier and is orally bioavailable. This compound is primarily utilized in research related to Alzheimer's disease [1].Fórmula:C18H19N5OForma y color:SolidPeso molecular:321.38AChE/Aβ-IN-5
CAS:Compound AV-2, also known as AChE/Aβ-IN-5, is a bifunctional inhibitor that acts on AChE and auto-induced Aβ (Amyloid-β) aggregation. This compound has demonstrated significant efficacy in mitigating cognitive impairment in mice induced by scopolamine and Aβ [1].Fórmula:C25H24N4Forma y color:SolidPeso molecular:380.48SRI-31255
CAS:SRI-31255 is an orally active LRRK2 inhibitor, with IC50 values of 520 nM for human wild-type (WT) and 427 nM for the G2019S mutant. It inhibits kinase activity by binding to the ATP-binding pocket of LRRK2, providing neuroprotective effects. SRI-31255 serves as a lead compound for developing LRRK2-targeted therapies for Parkinson’s disease research.Fórmula:C15H14N4Forma y color:SolidPeso molecular:250.30Amyloid-β-IN-2
CAS:Amyloid-β-IN-2 (Compound EX.112) is a selective inhibitor of γ-secretase. In H4 cells, it demonstrates inhibitory activity on Aβ42 secretion, with an EC50 value of 226 nM. Amyloid-β-IN-2 holds potential for research in Alzheimer's disease (AD) and diseases associated with Aβ deposition.Fórmula:C22H21F2N3O2Forma y color:SolidPeso molecular:397.425-HT2A receptor agonist-7
CAS:5-HT2A receptor agonist-7 (517) functions as a modulator of the 5-HT2A receptor, with an EC50 value of less than 100 nM.Fórmula:C12H11F2N3Forma y color:SolidPeso molecular:235.233YM-31636 free base
CAS:YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.Fórmula:C14H11N3SForma y color:SolidPeso molecular:253.32F 14679
CAS:F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.Fórmula:C21H25ClF2N4OPureza:99.09%Forma y color:SolidPeso molecular:422.9p-F-HHSiD hydrochloride
CAS:p-F-HHSiD (p-Fluorohexahydrosiladifenidol) hydrochloride is a selective M3mAChR antagonist. It is capable of inhibiting acetylcholine-mediated vasodilation in human umbilical vein endothelial cells (HUVEC).Fórmula:C20H33ClFNOSiPeso molecular:386.019Thiazolo[5,4-c]pyridin-4(5H)-one
CAS:Thiazolo[5,4-c]pyridin-4(5H)-one is a compound used for diagnostic imaging of TDP-43, in PET imaging of neurodegenerative diseases ALS、AD、FTD、LATE.Fórmula:C22H22FN5O2SPureza:98.75%Forma y color:SolidPeso molecular:439.51AM9405
AM9405: peripheral CB1/5-HT3 agonist, suppresses gut motility, relieves GI disorder symptoms in mice.Fórmula:C24H33BrN2O2Pureza:98%Forma y color:SolidPeso molecular:461.44DL-Thyroxine
CAS:DL-Thyroxine is a thyroid hormone that acts as a monoamine oxidase (monoamine oxidase) inhibitor.Fórmula:C15H11I4NO4Forma y color:SolidPeso molecular:776.87MAO-B-IN-44
CAS:MAO-B-IN-44 (Compound 4n) is a selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 1.01 μM, demonstrating weak inhibition of MAO-A (IC50=14.4 μM). It reduces the degradation of neurotransmitters like dopamine and holds potential for research into neurodegenerative diseases such as Parkinson's disease, which are associated with MAO-B abnormalities.Fórmula:C34H32N4O8Forma y color:SolidPeso molecular:624.64R-137696
CAS:R-137696 is an orally active 5-HT1A receptor agonist that facilitates the relaxation of the proximal stomach. It is utilized in research related to functional dyspepsia.Fórmula:C17H23N3O2Forma y color:SolidPeso molecular:301.38
![Thiazolo[5,4-c]pyridin-4(5H)-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT88035.webp&w=3840&q=75)
