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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5400 productos de "Neurociencia"

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  • Pomaglumetad methionil

    CAS:
    <p>Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.</p>
    Fórmula:C12H20N2O8S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:384.43
  • PF-06751979

    CAS:
    <p>PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).</p>
    Fórmula:C18H19F2N5O3S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:455.5
  • MAO-B-IN-28

    CAS:
    <p>MAO-B-IN-28 (compound 10e) is a potent hMAO-B inhibitor with an IC50 value of 1.9±0.5 nM, potentially serving as a candidate molecule for neurodegenerative disease research.</p>
    Fórmula:C19H10F3NO4S
    Peso molecular:405.35
  • UB 165

    CAS:
    <p>Subtype-selective nicotinic agonist</p>
    Fórmula:C13H15ClN2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:234.72
  • QP5020

    CAS:
    <p>QP5020 is a QPCTL inhibitor with an IC50 value of 15 nM, demonstrating antitumor efficacy.</p>
    Fórmula:C20H19FN6
    Peso molecular:362.40
  • AChE-IN-47

    CAS:
    <p>AChE-IN-47 (compound g17) is an acetylcholinesterase (AChE) inhibitor with an IC50 of 0.24 μM. It prevents the self-aggregation of β-amyloid peptides and exhibits neuroprotective properties by effectively reducing the accumulation of intracellular reactive oxygen species (ROS).</p>
    Fórmula:C20H17F3N4O4S
    Peso molecular:466.43
  • AChE/BChE-IN-24

    CAS:
    <p>AChE/BChE-IN-24 (compound 5k) functions as a neuroprotective agent by inhibiting acetylcholinesterase. It targets both AChE and BChE, demonstrating IC50 values of 16.38 μM and 10.44 μM, respectively.</p>
    Fórmula:C20H21N3
    Forma y color:Solid
    Peso molecular:303.4
  • LY2794193

    CAS:
    <p>LY2794193, a potent and selective mGlu3 receptor agonist, reduces akathisia seizures and increases GAT1, GLAST and GLT-1 protein levels in rats.</p>
    Fórmula:C16H18N2O6
    Pureza:98.15%
    Forma y color:Solid
    Peso molecular:334.32
  • CL-13


    <p>CL-13 is an inhibitor of butyrylcholinesterase (BChE), exhibiting an IC50 of 1.15 μM and a selectivity index (SI) of 9.2 for acetylcholinesterase. It demonstrates antioxidative activity in SH-SY5Y cells with a DPPHEC50 of 47.01 μM and has the capacity to chelate metals involved in Aβ aggregation and/or oxidative stress, showing no neurotoxicity at concentrations up to 50 μM. CL-13 can also reverse scopolamine-induced cognitive impairments without affecting motor abilities in mice.</p>
    Fórmula:C29H32N4OS
    Forma y color:Solid
    Peso molecular:484.66
  • 2,6-Dimethoxybenzylamine hydrochloride

    CAS:
    <p>2,6-Dimethoxybenzylamine hydrochloride (Compound 5) exhibits reversible inhibitory activity against copper amine oxidase (CAO) and inhibits benzylamine oxidase (BAO) and monoamine oxidase B (MAO B) with IC50 values of 120 μM and 190 μM, respectively.</p>
    Fórmula:C9H14ClNO2
    Forma y color:Solid
    Peso molecular:203.666
  • Sulamserod hydrochloride

    CAS:
    <p>Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.</p>
    Fórmula:C19H29Cl2N3O5S
    Forma y color:Solid
    Peso molecular:482.42
  • DA-8031

    CAS:
    <p>DA-8031 is a selective and orally active serotonin reuptake inhibitor. It is utilized in research related to premature ejaculation (PE).</p>
    Fórmula:C21H24N2O2
    Forma y color:Solid
    Peso molecular:336.43
  • Nafimidone hydrochloride

    CAS:
    <p>Nafimidone hydrochloride, an antiepileptic agent, inhibits acetylcholinesterase, protects neurons, and ameliorates cognitive decline. It is utilized in epilepsy research.</p>
    Fórmula:C15H13ClN2O
    Forma y color:Solid
    Peso molecular:272.73
  • RTIOXA-43

    CAS:
    <p>RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.</p>
    Fórmula:C37H37N5O5S
    Pureza:99.17%
    Forma y color:Solid
    Peso molecular:663.79
  • SEP-363856 mesylate

    CAS:
    <p>SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.</p>
    Fórmula:C10H17NO4S2
    Forma y color:Solid
    Peso molecular:279.38
  • MADAM

    CAS:
    <p>MADAM demonstrates high affinity and selectivity for 5-HTT, with a Ki value of 1.6 nM. It is utilized as a PET radiotracer for visualizing serotonin transporters.</p>
    Fórmula:C16H20N2S
    Forma y color:Solid
    Peso molecular:272.408
  • SB 243213 hydrochloride

    CAS:
    <p>SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).It</p>
    Fórmula:C22H20ClF3N4O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:464.87
  • Notch inhibitor 1

    CAS:
    <p>Notch inhibitor 1 blocks Notch 1/3 (IC50: 7.8/8.5 nM) and aids cancer research.</p>
    Fórmula:C26H25F7N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:574.49
  • hMAO-B-IN-10


    <p>hMAO-B-IN-10 (compound 7) is an inhibitor of MAO-A/B with IC50 values of 424.1 nM and 177.9 nM, respectively. It has demonstrated neuroprotective effects in the MPTP-induced mouse model of Parkinson's Disease (PD).</p>
    Fórmula:C16H12N4O4
    Forma y color:Solid
    Peso molecular:324.29
  • Elzasonan hydrochloride

    CAS:
    <p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>
    Fórmula:C22H24Cl3N3OS
    Forma y color:Solid
    Peso molecular:484.87