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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5397 productos de "Neurociencia"

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  • Neral
    Targetmol
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    Neral

    CAS:
    <p>Neral, a monoterpenoid compound, exhibits anti-inflammatory and anticancer activities. It inhibits TNF-α and IL-6, along with inflammatory mediators such as pro-IL-1β, iNOS, COX-2, and NLRP-3.</p>
    Fórmula:C10H16O
    Forma y color:Solid
    Peso molecular:152.23

    Ref: TM-T201808

  • SNRI-IN-1
    Targetmol
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    SNRI-IN-1

    CAS:
    <p>SNRI-IN-1 (Compound 7a) acts as a dual inhibitor of serotonin and noradrenaline monoamine reuptake, with a P-glycoprotein Efflux Ratio of 20 [1].</p>
    Fórmula:C16H20Cl2N2O2
    Forma y color:Solid
    Peso molecular:343.25

    Ref: TM-T87412

  • Logo de CymitQuimica
    Targetmol
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    BChE-IN-3

    <p>BChE-IN-3: Selective, pseudo-irreversible BChE inhibitor (IC50: 56.9 nM); borderline reversible AChE inhibitor.</p>
    Fórmula:C26H41N3O2
    Forma y color:Solid
    Peso molecular:427.62

    Ref: TM-T62336

  • MAO-B-IN-40
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    MAO-B-IN-40

    CAS:
    <p>MAO-B-IN-40 (3a) is an inhibitor of MAOB, exhibiting an IC50 value of 0.493 μM against hMAOB, and demonstrates significant neuroprotective and antioxidant effects. MAO-B-IN-40 (3a) is applicable in Parkinson's disease research.</p>
    Fórmula:C17H15N3O3
    Forma y color:Solid
    Peso molecular:309.319

    Ref: TM-T206123

  • Logo de CymitQuimica
    Targetmol
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    SB 258741 hydrochloride

    <p>SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].</p>
    Fórmula:C19H31ClN2O2S
    Forma y color:Solid
    Peso molecular:386.98

    Ref: TM-T61724

  • MMB-4
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    MMB-4

    CAS:
    <p>MMB-4 is an oxime that can reactivate cholinesterases (cholinesterases) which have been inactivated due to exposure to organophosphates such as Sarin or Soman.</p>
    Fórmula:C13H14Br2N4O2
    Forma y color:Solid
    Peso molecular:418.084

    Ref: TM-T204634

  • 5-HT1A modulator 4
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    5-HT1A modulator 4

    CAS:
    <p>5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.</p>
    Fórmula:C9H14N4
    Forma y color:Solid
    Peso molecular:178.234

    Ref: TM-T205724

  • AChE-IN-83
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    AChE-IN-83

    CAS:
    <p>AChE-IN-83 (compound f1) is an AChE inhibitor that suppresses nematode growth and acetylcholinesterase activity in rice seeds while being safe for the seeds. It specifically targets Aphelenchoides besseyi, with an LC50 of 19.0 μg/mL over 48 hours. AChE-IN-83 impedes nematode populations and behaviors in rice seeds, damages the nematode cuticle, and induces reactive oxygen species, lipofuscin, and lipid generation within the nematodes.</p>
    Fórmula:C10H7ClN2O2S
    Forma y color:Solid
    Peso molecular:254.693

    Ref: TM-T205656

  • ChEs/MAOs-IN-2
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    ChEs/MAOs-IN-2

    CAS:
    <p>ChEs/MAOs-IN-2 (compound a11) serves as an inhibitor for both cholinesterases and monoamine oxidases, exhibiting IC 50 values of 0.10 µM for MAO-A, 0.20 µM for MAO-B, 0.30 µM for AChE, and 0.40 µM for BChE. This compound shows promise for Alzheimer's disease research [1].</p>
    Fórmula:C15H12N2O3S
    Forma y color:Solid
    Peso molecular:300.33

    Ref: TM-T86047

  • Geissoschizoline
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    Geissoschizoline

    CAS:
    <p>Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.</p>
    Fórmula:C19H26N2O
    Forma y color:Solid
    Peso molecular:298.42

    Ref: TM-T72733

  • Etoperidone
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    Etoperidone

    CAS:
    <p>Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).</p>
    Fórmula:C19H28ClN5O
    Forma y color:Solid
    Peso molecular:377.91

    Ref: TM-T201838

  • LOXL2-IN-1 tosylate
    Targetmol
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    LOXL2-IN-1 tosylate

    <p>LOX-IN-5 tosylate (compound 22) is a selective oral inhibitor of lysyl oxidase-like 2 (LOXL2) with an IC50 of less than 300 nM, and it exhibits anti-fibrotic properties.</p>
    Fórmula:C28H33FN4O5S2
    Forma y color:Solid
    Peso molecular:588.714

    Ref: TM-T205044

  • MAO-A inhibitor 3
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    MAO-A inhibitor 3

    CAS:
    <p>MAO-A inhibitor3 (Compound 360) is an MAO-A inhibitor with an IC50 greater than 100 μM. It is utilized in the investigation of neurological disorders.</p>
    Fórmula:C11H8O5
    Forma y color:Solid
    Peso molecular:220.178

    Ref: TM-T205117

  • hAChE-IN-10
    Targetmol
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    hAChE-IN-10

    CAS:
    <p>hAChE-IN-10 (Compound ET11) is an inhibitor of human acetylcholinesterase (AChE) with an IC50 of 6.34 nM. This compound is capable of scavenging free radicals and exhibits antioxidant activity. Additionally, hAChE-IN-10 demonstrates metal-chelating properties, inhibiting Cu2+-induced Aβ1-42 aggregation, reducing amyloid plaque formation, and offering neuroprotective effects. It also ameliorates cognitive impairment in mice induced by Scopolamine.</p>
    Fórmula:C25H24ClFN6O2
    Forma y color:Solid
    Peso molecular:494.948

    Ref: TM-T204876

  • Ro4368554
    Targetmol
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    Ro4368554

    CAS:
    <p>Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.</p>
    Fórmula:C19H21N3O2S
    Forma y color:Solid
    Peso molecular:355.454

    Ref: TM-T204915

  • GABA-IN-4
    Targetmol
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    GABA-IN-4

    CAS:
    <p>GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.</p>
    Fórmula:C17H13ClN2O2
    Forma y color:Solid
    Peso molecular:312.75

    Ref: TM-T205501

  • MADAM
    Targetmol
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    MADAM

    CAS:
    <p>MADAM demonstrates high affinity and selectivity for 5-HTT, with a Ki value of 1.6 nM. It is utilized as a PET radiotracer for visualizing serotonin transporters.</p>
    Fórmula:C16H20N2S
    Forma y color:Solid
    Peso molecular:272.408

    Ref: TM-T204693

  • BF-168
    Targetmol
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    BF-168

    CAS:
    <p>BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).</p>
    Fórmula:C18H17FN2O2
    Forma y color:Solid
    Peso molecular:312.34

    Ref: TM-T10529

  • 5-IAI hydrochloride
    Targetmol
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    5-IAI hydrochloride

    CAS:
    <p>5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.</p>
    Fórmula:C9H11ClIN
    Forma y color:Solid
    Peso molecular:295.548

    Ref: TM-T204949

  • Logo de CymitQuimica
    Targetmol
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    (+)-Sparteine sulfate pentahydrate

    <p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>
    Fórmula:C15H38N2O9S
    Forma y color:Solid
    Peso molecular:422.54

    Ref: TM-T62265