Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(1.024 productos)
- ACK(1 productos)
- AChR(624 productos)
- ATP Citrato Liasa(17 productos)
- Receptor adrenérgico(3.029 productos)
- BACE(36 productos)
- Beta amiloide(224 productos)
- CAMK(73 productos)
- Inhibidores de ciclooxigenasa (COX)(600 productos)
- Receptor de dopamina(443 productos)
- Receptor GABA(365 productos)
- Gamma-secretasa(62 productos)
- GluR(263 productos)
- GlyT(26 productos)
- Receptor de histamina(385 productos)
- LRRK2(42 productos)
- Receptor de melatonina(26 productos)
- NMDAR(10 productos)
- Receptor de OX(42 productos)
- Receptor de opioides(326 productos)
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Se han encontrado 5559 productos de "Neurociencia"
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AChE-IN-25
AChE-IN-25: selective, potent AChE inhibitor, non-competitive, IC50 = 2.95 μM, for Alzheimer's research.Fórmula:C20H15ClN4O4SForma y color:SolidPeso molecular:442.882002-G12
CAS:2002-G12 (compound 5a) is an Aβ42 inhibitor that can reduce Aβ42 toxicity by 76%. It is applicable in Alzheimer's research.Fórmula:C20H16N6Forma y color:SolidPeso molecular:340.381Rodatristat
CAS:Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).Fórmula:C27H27ClF3N5O3Pureza:98%Forma y color:SolidPeso molecular:561.98γ-Secretase modulator 11 hydrochloride
CAS:γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM).Fórmula:C28H23ClF2N4O2Forma y color:SolidPeso molecular:520.96AChE-IN-10
AChE-IN-10 (24r) inhibits AChE (IC50=2.4 nM), reducing amyloid buildup, tau phosphorylation, and promotes neuron health.Fórmula:C23H27F2NO4SForma y color:SolidPeso molecular:451.53Alixorexton
CAS:Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.Fórmula:C21H30N2O5SForma y color:SolidPeso molecular:422.538SB 258741 hydrochloride
SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].Fórmula:C19H31ClN2O2SForma y color:SolidPeso molecular:386.98hAChE/Aβ1-42-IN-1
CAS:Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines andFórmula:C20H24N6OForma y color:SolidPeso molecular:364.44(+)-Sparteine sulfate pentahydrate
(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.Fórmula:C15H38N2O9SForma y color:SolidPeso molecular:422.54U92016A hydrochloride
CAS:U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.Fórmula:C19H26ClN3Forma y color:SolidPeso molecular:331.89BChE-IN-2
BChE-IN-2, a pyrimidine/pyridine derivative, potently inhibits BChE (Ki 0.099 μM) and shows promise in AD research.Fórmula:C22H31N5Forma y color:SolidPeso molecular:365.52Geissoschizoline
CAS:Geissoschizoline inhibits human AChE/BChE (IC50: 20.40/10.21 µM) and has anti-inflammatory properties.Fórmula:C19H26N2OForma y color:SolidPeso molecular:298.42LRRK2-IN-6
LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).Fórmula:C23H24F2N4O2SForma y color:SolidPeso molecular:458.52AChE/BACE1/GSK3β-IN-1
AChE/BACE1/GSK3β-IN-1 is an orally active, blood-brain barrier-transparent, moderately bioavailable triple inhibitor of AChE/BACE1/GSK3β.Fórmula:C26H27FN2O4Forma y color:SolidPeso molecular:450.5MAO-B-IN-42
CAS:<p>MAO-B-IN-42 (Compound 4f) is a selective and reversible monoamine oxidase-B (MAO-B) inhibitor, with an IC50 value of 0.184 μM. By blocking the oxidative deamination of monoamines catalyzed by MAO-B, it helps maintain neurotransmitter levels. MAO-B-IN-42 shows potential for research into Parkinson's disease.</p>Fórmula:C19H12FNO2Forma y color:SolidPeso molecular:305.3025-HT6R/MAO-B modulator 1
5-HT6R/MAO-B modulator 1 blocks 5-HT6R and permanently inhibits MAO-B, protects glial cells, and reverses memory loss.Fórmula:C33H38N4O3SForma y color:SolidPeso molecular:570.74AChE/BChE/MAO-B-IN-5
CAS:AChE/BChE/MAO-B-IN-5 is a multi-target inhibitor capable of crossing the blood-brain barrier, targeting cholinesterases (AChE and BChE) and monoamine oxidase MAO-B. It exhibits IC50 values of 0.24 µM for AChE, 6.29 µM for BChE, and 0.11 µM for MAO-B. AChE/BChE/MAO-B-IN-5 holds potential for research in neurodegenerative diseases such as Alzheimer's disease.Fórmula:C22H14F3NO2Forma y color:SolidPeso molecular:381.347PXS-5153A monohydrochloride
CAS:PXS-5153A is an oral, fast-acting LOXL2/3 inhibitor with IC50 <40 nM for LOXL2 and 63 nM for LOXL3, potentially treating fibrosis.Fórmula:C20H25Cl2FN4O2SPureza:98%Forma y color:Odour SolidPeso molecular:475.41FP0429
CAS:FP0429 is an agonist of mGlu4.Fórmula:C10H12N2O7Pureza:98%Forma y color:SolidPeso molecular:272.21MADAM
CAS:MADAM demonstrates high affinity and selectivity for 5-HTT, with a Ki value of 1.6 nM. It is utilized as a PET radiotracer for visualizing serotonin transporters.Fórmula:C16H20N2SForma y color:SolidPeso molecular:272.408
