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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5398 productos de "Neurociencia"

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  • BChE-IN-39


    <p>BChE-IN-39 (Compound 7c) selectively inhibits butyrylcholinesterase (BChE) with an IC50 of 0.08 μM, while showing an IC50 of 3.98 μM for acetylcholinesterase (AChE) inhibition. Additionally, BChE-IN-39 downregulates GSK-3β expression, thereby inhibiting the excessive phosphorylation of tau protein.</p>
    Fórmula:C29H23ClFN3O3
    Forma y color:Solid
    Peso molecular:515.963
  • JF-NP-26


    <p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>
    Forma y color:Solid
  • HTR2A antagonist 1


    <p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>
    Fórmula:C35H43Cl2F2N5O4
    Forma y color:Solid
    Peso molecular:706.65
  • Neuronal Signaling Compound Library


    <p>A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>
    Forma y color:Odour Solid
  • 5-HT6R antagonist 6


    <p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>
    Fórmula:C24H26N4O2S
    Forma y color:Solid
    Peso molecular:434.55
  • Aminoacetone hydrochloride

    CAS:
    <p>Aminoacetone hydrochloride (1-Aminoacetone Hydrochloride) is an oxidative agent that induces loss of ferritin ferrireductase activity and iron uptake.</p>
    Fórmula:C3H8ClNO
    Pureza:99.76%
    Forma y color:Solid
    Peso molecular:109.56
  • 5-HT5AR/5-HT6R ligand-1


    <p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>
    Fórmula:C25H30N4O2S
    Forma y color:Solid
    Peso molecular:450.6
  • ACHE Inhibitor 12

    CAS:
    <p>ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.</p>
    Fórmula:C11H12O
    Pureza:98.71%
    Forma y color:Solid
    Peso molecular:160.21
  • [Ala11,D-Leu15]-Orexin B acetate


    <p>[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).</p>
    Fórmula:C122H210N44O37S
    Pureza:98.18%
    Forma y color:Solid
    Peso molecular:2917.31
  • AL 34662

    CAS:
    <p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>
    Fórmula:C10H13N3O
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:191.23
  • RuBi-GABA

    CAS:
    <p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>
    Fórmula:C42H39F6N5O2P2Ru
    Pureza:98%
    Forma y color:Solid
    Peso molecular:922.8
  • Heliosupine


    <p>Heliosupine is a useful organic compound for research related to life sciences and the catalog number is T125038.</p>
    Fórmula:C20H31NO7
    Forma y color:Solid
    Peso molecular:397.468
  • epi-Aszonalenin A

    CAS:
    <p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>
    Fórmula:C25H25N3O3
    Forma y color:Solid
    Peso molecular:415.48
  • (±)-Acetylcarnitine chloride

    CAS:
    <p>(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with neuroprotective properties and can be used in studies of neuritis.</p>
    Fórmula:C9H18ClNO4
    Pureza:99.98%
    Forma y color:White Crystalline Powder
    Peso molecular:239.7
  • p-MPPF

    CAS:
    <p>p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.</p>
    Fórmula:C25H27FN4O2
    Pureza:99.92%
    Forma y color:Solid
    Peso molecular:434.51
  • AChE/BuChE-IN-6


    <p>AChE/BuChE-IN-6 (Compound 11f) is an inhibitor of AChE and BuChE, with IC50 values of 1.24 and 1.85 μg/mL, respectively. It exhibits strong DPPH radical scavenging activity (IC50 = 3.15 μg/mL). In vivo toxicity studies demonstrate that AChE/BuChE-IN-6 is safe, showing no significant differences in blood and biochemical parameters compared to controls, and no abnormalities in liver and kidney tissues. This compound shows potential for Alzheimer's disease research.</p>
    Fórmula:C24H20ClN3O3
    Forma y color:Solid
    Peso molecular:433.887
  • hAChE/hBuChE-IN-1


    <p>hAChE/hBuChE-IN-1 (compound C2) acts as a dual inhibitor of cholinesterases, exhibiting IC50 values of 514 nM for hAChE and 358 nM for hBuChE. It is orally active and capable of enhancing cognitive function and spatial memory.</p>
    Fórmula:C30H31FN2O3
    Forma y color:Solid
    Peso molecular:486.577
  • Mosapride citrate dihydrate

    CAS:
    <p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>
    Fórmula:C27H35ClFN3O11
    Pureza:98%
    Forma y color:Solid
    Peso molecular:632.04
  • α-Conotoxin EI

    CAS:
    <p>Selective antagonist of neuromuscular nicotinic receptors α1β1γδ</p>
    Fórmula:C83H125N27O27S5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2093.37
  • Pseudocoptisine acetate

    CAS:
    <p>Pseudocoptisine acetate is a quaternary alkaloid isolated from the tubers of Corydalis turtschaninovii,with anti-inflammatory properties.</p>
    Fórmula:C21H17NO6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:379.36