Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(940 productos)
- ACK(1 productos)
- AChR(574 productos)
- ATP Citrato Liasa(16 productos)
- Receptor adrenérgico(2.939 productos)
- BACE(36 productos)
- Beta amiloide(204 productos)
- CAMK(68 productos)
- Inhibidores de ciclooxigenasa (COX)(562 productos)
- Receptor de dopamina(407 productos)
- Receptor GABA(336 productos)
- Gamma-secretasa(59 productos)
- GluR(255 productos)
- GlyT(24 productos)
- Receptor de histamina(358 productos)
- LRRK2(33 productos)
- Receptor de melatonina(24 productos)
- NMDAR(28 productos)
- Receptor de OX(40 productos)
- Receptor de opioides(296 productos)
Mostrar 12 subcategorías más
Se han encontrado 5400 productos de "Neurociencia"
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Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Fórmula:C16H12ClNO3Pureza:98.87%Forma y color:SolidPeso molecular:301.72Eslicarbazepine
CAS:<p>Eslicarbazepine (Stedesa) can be used for adjunctive therapy for adults with partial-onset seizures.</p>Fórmula:C15H14N2O2Pureza:99.97%Forma y color:Off-White SolidPeso molecular:254.28L-822179
CAS:<p>L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.</p>Fórmula:C17H14N8O2Pureza:98.5% - 99.61%Forma y color:SolidPeso molecular:362.35Biphenylindanone A
CAS:<p>Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.</p>Fórmula:C30H30O4Pureza:98%Forma y color:SolidPeso molecular:454.56C3
CAS:<p>C3 functions as a selective inhibitor of monoamine oxidase B (MAO-B; IC50= 0.021 µM), demonstrating preference over monoamine oxidase A (MAO-A; IC50= 26.8 µM). This compound, at dosages of 0.1, 1, and 3 mg/kg, effectively counters MPTP-induced reductions in dopamine levels within the mouse brain.</p>Fórmula:C18H19FN2O2Forma y color:SolidPeso molecular:314.35Cyanopindolol fumarate
CAS:<p>Cyanopindolol fumarate is a 5-HT receptor antagonist [1].</p>Fórmula:C16H21N3O2C4H4O4Forma y color:SolidPeso molecular:345.4RAGE/SERT-IN-1
CAS:<p>RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM and</p>Fórmula:C38H41ClN4OSForma y color:SolidPeso molecular:637.28LY3202626
CAS:<p>LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.</p>Fórmula:C22H20F2N8O2SPureza:98%Forma y color:SolidPeso molecular:498.51JM-1232
CAS:<p>JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.</p>Fórmula:C24H27N3O2Forma y color:SolidPeso molecular:389.49BACE1-IN-13
CAS:<p>BACE1-IN-13 (Compound 36), an orally active inhibitor of BACE1, exhibits high potency with an IC50 of 2.9 nM and demonstrates greater efficacy in hAβ42 cells (</p>Fórmula:C20H17FN8O2Pureza:98%Forma y color:SolidPeso molecular:420.4BMT-124110
CAS:<p>BMT-124110: AAK1 inhibitor, IC50=0.9 nM, pain relief. BMT-090605: BIKE inhibitor, IC50=17 nM; GAK inhibitor, IC50=99 nM.</p>Fórmula:C21H27N3O3Pureza:98.07%Forma y color:SolidPeso molecular:369.46LY108742
CAS:<p>LY108742 is an antagonist of 5-HT2.</p>Fórmula:C21H28N2O3Pureza:98%Forma y color:SolidPeso molecular:356.46Befiradol
CAS:<p>Befiradol (NLX-112) is an agonist of 5-HT1A receptor.</p>Fórmula:C20H22ClF2N3OForma y color:SolidPeso molecular:393.86Fosthiazate
CAS:<p>Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., by</p>Fórmula:C9H18NO3PS2Pureza:97.78%Forma y color:SolidPeso molecular:283.35Robalzotan
CAS:<p>Robalzotan is a selective 5-HT1A receptor antagonist.</p>Fórmula:C18H23FN2O2Pureza:98%Forma y color:SolidPeso molecular:318.39SCS
CAS:<p>SCS is a GABAA receptor antagonist.</p>Fórmula:C14H12N2O3Pureza:99.73%Forma y color:SolidPeso molecular:256.26GR 127935 hydrochloride
CAS:<p>5-HT1B/1D receptor antagonist</p>Fórmula:C29H32ClN5O3Pureza:98%Forma y color:SolidPeso molecular:534.05CGP 55845 hydrochloride
CAS:<p>CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].</p>Fórmula:C18H23Cl3NO3PForma y color:SolidPeso molecular:438.71Muscarine tosylate
CAS:<p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>Fórmula:C16H27NO5SForma y color:SolidPeso molecular:345.45(+)-Bicuculline methiodide
CAS:<p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>Fórmula:C21H20INO6Pureza:99.24%Forma y color:SolidPeso molecular:509.29MFZ 10-7
CAS:<p>MFZ 10-7 is anegative allosteric modulator of the mGluR5.</p>Fórmula:C15H9FN2Pureza:99.80%Forma y color:SolidPeso molecular:236.24AMG-8718
CAS:<p>AMG-8718, an oral BACE1 blocker (IC50: 0.0007 μM), also inhibits BACE2 (IC50: 0.005 μM), lowering CSF and Aβ40 brain levels.</p>Fórmula:C25H19FN4O3Forma y color:SolidPeso molecular:442.44eeAChE-IN-2
CAS:<p>eeAChE-IN-2 is a potent inhibitor of eeAChE, exhibiting inhibitory potency with an IC50 of 2 nM.</p>Fórmula:C37H40N8O5SForma y color:SolidPeso molecular:708.83(S)-Renzapride
<p>(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.</p>Fórmula:C16H22ClN3O2Forma y color:SolidPeso molecular:323.82MAO-IN-3
CAS:<p>MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B,</p>Fórmula:C42H54N4O4Pureza:98%Forma y color:SolidPeso molecular:678.9CGP 64213
CAS:<p>CGP 64213 is a GABAb receptor agonist.</p>Fórmula:C26H36IN2O7PPureza:98%Forma y color:SolidPeso molecular:646.45NAD 299 hydrochloride
CAS:<p>Selective, high affinity 5-HT1A receptor antagonist</p>Fórmula:C18H24ClFN2O2Pureza:98%Forma y color:SolidPeso molecular:354.85AChE-IN-19
CAS:<p>AChE-IN-19: strong AChE blocker (IC50: 0.56 μM), hinders Aβ clumps, neuro-protective, non-toxic to SH-SY5Y, for Alzheimer's research.</p>Fórmula:C30H33NO7Forma y color:SolidPeso molecular:519.595-HT2C agonist-3
CAS:<p>5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-induced</p>Fórmula:C19H23ClFNO2Pureza:98%Forma y color:SolidPeso molecular:351.84Adipiplon
CAS:<p>Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.</p>Fórmula:C18H18FN7Forma y color:SolidPeso molecular:351.38N-Demethyl MK-6884
CAS:<p>N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.</p>Fórmula:C24H23N5OForma y color:SolidPeso molecular:397.47Physostigmine hemisulfate
CAS:<p>cholinesterase inhibitor</p>Fórmula:C15H21N302H204SPureza:98%Forma y color:SolidPeso molecular:324.39L 663581
CAS:<p>L 663581 is the benzodiazepine receptor partial agonist.</p>Fórmula:C17H16ClN5O2Pureza:98%Forma y color:SolidPeso molecular:357.79PTAC oxalate
CAS:<p>muscarinic receptor ligand</p>Fórmula:C14H21N3O4S2Pureza:98%Forma y color:SolidPeso molecular:359.46Zamifenacin fumarate
CAS:<p>Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.</p>Fórmula:C31H33NO7Pureza:99.88%Forma y color:SolidPeso molecular:531.65-HT2C agonist-3 free base
CAS:<p>5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-</p>Fórmula:C19H22FNO2Pureza:98%Forma y color:SolidPeso molecular:315.38NAS181
CAS:<p>rat 5-HT1B receptor antagonist</p>Fórmula:C21H34N2O10S2Pureza:98%Forma y color:SolidPeso molecular:538.63Tiotropium Bromide hydrate
CAS:<p>Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.</p>Fórmula:C19H24BrNO5S2Pureza:98.44% - 99.41%Forma y color:SolidPeso molecular:490.435-HT2A antagonist 1
CAS:<p>5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.</p>Fórmula:C26H28N4O2Pureza:98%Forma y color:SolidPeso molecular:428.53LY-426965
CAS:<p>LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.</p>Fórmula:C28H38N2O2Forma y color:SolidPeso molecular:434.615-HT2 agonist-1 free base
CAS:<p>Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,</p>Fórmula:C19H22N2O2Pureza:98%Forma y color:SolidPeso molecular:310.39TPA 023
CAS:<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Fórmula:C20H22FN7OPureza:99.75%Forma y color:SolidPeso molecular:395.43NCS-382 sodium
CAS:<p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>Fórmula:C13H13NaO3Pureza:98%Forma y color:SolidPeso molecular:240.23Pregnanolone sulfate (pyridinium)
CAS:<p>Pregnanolone sulfate pyridinium, an endogenous neurosteroid, inhibits NMDA receptors and exhibits neuroprotective properties [1].</p>Fórmula:C26H39NO5SPureza:98%Forma y color:SolidPeso molecular:477.66Adenylyl cyclase-IN-1
CAS:<p>Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].</p>Fórmula:C9H8N2S3Forma y color:SolidPeso molecular:240.37Velusetrag
CAS:<p>Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.</p>Fórmula:C25H36N4O5SForma y color:SolidPeso molecular:504.64GABAA receptor agent 2 TFA
CAS:<p>Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.</p>Fórmula:C22H22F3N3O3Forma y color:SolidPeso molecular:433.42Brasofensine Maleate
CAS:<p>Brasofensine Maleate inhibits the monoamine re-uptake.</p>Fórmula:C20H24Cl2N2O5Forma y color:SolidPeso molecular:443.32AMPA receptor modulator-6
CAS:<p>AMPA receptor modulator-6, an AMPA receptor positive allosteric modulator (PAM), is utilized in the research of neurological diseases [1].</p>Fórmula:C24H36N2O4S2Pureza:98%Forma y color:SolidPeso molecular:480.68L-AP4
CAS:<p>L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).</p>Fórmula:C4H10NO5PPureza:98%Forma y color:White To Off-White Crystalline PowderPeso molecular:183.1VU6004909
CAS:<p>VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.</p>Fórmula:C21H15FN2O4Pureza:96.68% - 98.44%Forma y color:SolidPeso molecular:378.35Rislenemdaz
CAS:<p>Rislenemdaz (CERC-301) (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B).</p>Fórmula:C19H23FN4O2Pureza:98.18%Forma y color:SolidPeso molecular:358.41γ-Secretase-IN-1
CAS:<p>γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.</p>Fórmula:C27H24F2N4O3Pureza:99.56%Forma y color:SolidPeso molecular:490.5R-(+)-EU-1180-453
CAS:<p>R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.</p>Fórmula:C22H21FN2O3Pureza:99.63%Forma y color:SolidPeso molecular:380.41Dalzanemdor
CAS:<p>Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive</p>Fórmula:C27H43F3O2Pureza:98.2% - >99.99%Forma y color:SolidPeso molecular:456.62Gossypolone
CAS:<p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>Fórmula:C30H26O10Pureza:96.66%Forma y color:SolidPeso molecular:546.52Tematropium
CAS:<p>Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.</p>Fórmula:C21H31NO8SPureza:99.89%Forma y color:SolidPeso molecular:457.54WAY-607695
CAS:<p>WAY-607695 is a potential 5-HT1A receptor agonist.</p>Fórmula:C13H12FNO2Pureza:99.82%Forma y color:SolidPeso molecular:233.24BuChE-IN-TM-10
CAS:<p>TM-10: Potent BuChE inhibitor, IC50 8.9 nM, disaggregates Aβ, antioxidant, BBB penetrant, may treat Alzheimer's.</p>Fórmula:C32H38N2O3Pureza:99.54%Forma y color:SolidPeso molecular:498.66Didesmethyl cariprazine
CAS:<p>Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.</p>Fórmula:C19H28Cl2N4OPureza:99.52%Forma y color:SolidPeso molecular:399.36AMPA receptor modulator-1
CAS:<p>AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.</p>Fórmula:C16H11ClF3NO2Pureza:99.93%Forma y color:SolidPeso molecular:341.71Philanthotoxin 74 dihydrochloride
CAS:<p>Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.</p>Fórmula:C24H44Cl2N4O3Pureza:99.75%Forma y color:SolidPeso molecular:507.54TZ3O
CAS:<p>TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.</p>Fórmula:C18H13NO4SPureza:99.84%Forma y color:SolidPeso molecular:339.37SB 216641 hydrochloride
CAS:<p>SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.</p>Fórmula:C28H31ClN4O4Pureza:98.06% - 99.23%Forma y color:SolidPeso molecular:523.02JNJ-42253432
CAS:<p>JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels</p>Fórmula:C28H38N4OPureza:99.98%Forma y color:SolidPeso molecular:446.63Osemozotan HCl
CAS:<p>Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.</p>Fórmula:C19H22ClNO5Pureza:98.87% - 99.63%Forma y color:SolidPeso molecular:379.84Atabecestat
CAS:<p>Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.</p>Fórmula:C18H14FN5OSPureza:99.21% - 99.77%Forma y color:SolidPeso molecular:367.4CGP 78608 hydrochloride
CAS:<p>CGP 78608 hydrochloride: NMDA receptor antagonist (IC50=6 nM), anticonvulsant, enhances GluN1/GluN3A currents (EC50=26.3 nM).</p>Fórmula:C11H14BrClN3O5PPureza:99.85%Forma y color:SolidPeso molecular:414.58AMPA receptor antagonist-3
CAS:<p>AMPA receptor antagonist-3 is an AMPA receptor antagonist.</p>Fórmula:C20H19N5O2SPureza:99.79%Forma y color:SolidPeso molecular:393.46Lumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Fórmula:C24H28FN3OPureza:99.68% - 99.91%Forma y color:SolidPeso molecular:393.5PXS-5153A
CAS:<p>PXS-5153A rapidly inhibits lysyl oxidase 2/3 enzymes, blocks activity in 15 mins, and reduces fibrosis.</p>Fórmula:C20H25Cl2FN4O2SPureza:99.58%Forma y color:SolidPeso molecular:475.41MDR-1339
CAS:<p>MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.</p>Fórmula:C20H22O4Pureza:98.57%Forma y color:SolidPeso molecular:326.39PXS-5120A
CAS:<p>PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.</p>Fórmula:C22H25ClFN3O4SPureza:97.02%Forma y color:SolidPeso molecular:481.97SB-616234-A
CAS:<p>SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.</p>Fórmula:C32H36ClN5O3Pureza:99.72%Forma y color:SolidPeso molecular:574.11BMS-986176
CAS:<p>AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).</p>Fórmula:C19H23F4N3OPureza:98.58% - 98.7%Forma y color:SolidPeso molecular:385.4Nedemelteon
CAS:<p>Nedemelteon is an agonist of the melatonin receptor (melatonin receptor).</p>Fórmula:C15H18N2O2Forma y color:SolidPeso molecular:258.32LY3020371 hydrochloride
CAS:<p>LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.</p>Fórmula:C15H16ClF2NO5SForma y color:SolidPeso molecular:395.81CEase-IN-1
<p>CEase-IN-1 (A1H3), potent CEase inhibitor, IC50 0.36μM, for hypercholesterolemia study.</p>Fórmula:C13H15F3N2O2Forma y color:SolidPeso molecular:288.27EF1502 free base
CAS:<p>EF1502 is a potent and selective GABA transporter inhibitor.</p>Fórmula:C22H26N2O2S2Pureza:98%Forma y color:SolidPeso molecular:414.58SB 258741 hydrochloride
<p>SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].</p>Fórmula:C19H31ClN2O2SForma y color:SolidPeso molecular:386.98ChE/Aβ1-42-IN-1
<p>ChE/Aβ1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Aβ 1-42 with excellent BBB permeability.</p>Fórmula:C19H24N2O3Forma y color:SolidPeso molecular:328.41P2X7 receptor antagonist-5
CAS:<p>P2X7 receptor antagonist-5 (compound 13a) is a potent, orally active, and long-lasting antagonist of the P2X7 receptor.</p>Fórmula:C21H17F3N6O3S2Forma y color:SolidPeso molecular:522.52YM 202074
CAS:<p>metabotropic glutamate receptor type 1 (mGlu1) antagonist</p>Fórmula:C56H72N8O16S2Pureza:98%Forma y color:SolidPeso molecular:1177.34Cyproflanilide
CAS:<p>Cyproflanilide is a GABAR antagonist that exhibits high activity against a variety of pests, including those from the Lepidoptera, Coleoptera, and Thysanoptera orders.</p>Fórmula:C28H17BrF12N2O2Forma y color:SolidPeso molecular:721.33Rodatristat ethyl
CAS:<p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.</p>Fórmula:C29H31ClF3N5O3Pureza:98%Forma y color:SolidPeso molecular:590.04BGT1-IN-1
CAS:<p>BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.</p>Fórmula:C6H9NO2Forma y color:SolidPeso molecular:127.14(S)-YNT-3708
CAS:<p>(S)-YNT-3708 is the S-isomer of YNT-3708, demonstrating relatively low activity against OX1R and OX2R receptors, with EC50 values of 3595 nM and 1661 nM, respectively.</p>Fórmula:C35H36N4O6SForma y color:SolidPeso molecular:640.749P2X4 antagonist-1
CAS:<p>P2X4 antagonist-1 is a potent P2X4 receptor antagonist used in the study of neurological, cardiovascular, and immune system diseases.</p>Fórmula:C20H15Cl3N2O4SPureza:99.9%Forma y color:SolidPeso molecular:485.77(+)-Sparteine sulfate pentahydrate
<p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>Fórmula:C15H38N2O9SForma y color:SolidPeso molecular:422.54(E)-CHBO4
CAS:<p>(E)-CHBO4 is an MAO-B inhibitor with an IC50 value of 0.023 μM, making it a potential candidate for research into Parkinson's disease treatment.</p>Fórmula:C15H10BrFOForma y color:SolidPeso molecular:305.142γ-Secretase modulator 11 hydrochloride
CAS:<p>γ-Secretase modulator 11 hydrochloride is a potent, orally active γ-secretase modulator (IC50: 0.029 μM).</p>Fórmula:C28H23ClF2N4O2Forma y color:SolidPeso molecular:520.96Elzasonan hydrochloride
CAS:<p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>Fórmula:C22H24Cl3N3OSForma y color:SolidPeso molecular:484.87hMAO-B-IN-10
<p>hMAO-B-IN-10 (compound 7) is an inhibitor of MAO-A/B with IC50 values of 424.1 nM and 177.9 nM, respectively. It has demonstrated neuroprotective effects in the MPTP-induced mouse model of Parkinson's Disease (PD).</p>Fórmula:C16H12N4O4Forma y color:SolidPeso molecular:324.29CL-13
<p>CL-13 is an inhibitor of butyrylcholinesterase (BChE), exhibiting an IC50 of 1.15 μM and a selectivity index (SI) of 9.2 for acetylcholinesterase. It demonstrates antioxidative activity in SH-SY5Y cells with a DPPHEC50 of 47.01 μM and has the capacity to chelate metals involved in Aβ aggregation and/or oxidative stress, showing no neurotoxicity at concentrations up to 50 μM. CL-13 can also reverse scopolamine-induced cognitive impairments without affecting motor abilities in mice.</p>Fórmula:C29H32N4OSForma y color:SolidPeso molecular:484.66AChE-IN-8
<p>AChE-IN-8 (Compound 19), potent acetylcholinesterase blocker; IC50 = 1.95 μM; potential Alzheimer's treatment.</p>Fórmula:C20H22N4O2SForma y color:SolidPeso molecular:382.48AChE/BChE-IN-24
CAS:<p>AChE/BChE-IN-24 (compound 5k) functions as a neuroprotective agent by inhibiting acetylcholinesterase. It targets both AChE and BChE, demonstrating IC50 values of 16.38 μM and 10.44 μM, respectively.</p>Fórmula:C20H21N3Forma y color:SolidPeso molecular:303.4hAChE/Aβ1-42-IN-1
CAS:<p>Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines and</p>Fórmula:C20H24N6OForma y color:SolidPeso molecular:364.44BACE1-IN-8
<p>BACE1-IN-8 is a potent inhibitor of BACE1 (β-site APP lyase 1) (IC50: 3.9 μM).</p>Fórmula:C29H45N5O7Forma y color:SolidPeso molecular:575.7LRRK2-IN-3
CAS:<p>LRRK2-IN-3: potent, selective oral LRRK2 blocker, BBB-penetrant, IC50 of 0.6 nM in hPBMCs, for Parkinson's research.</p>Fórmula:C25H29ClF2N6O2Forma y color:SolidPeso molecular:518.991,9-Dideoxyforskolin
CAS:<p>The compound is an inactive analog of forskolin(an adenylyl cyclase activator).</p>Fórmula:C22H34O5Pureza:98%Forma y color:SolidPeso molecular:378.5MAO-A inhibitor 1
CAS:<p>MAO-A Inhibitor 1 (compound VIII) acts as a MAO-A inhibitor and exhibits an IC50 value of 100 μM [1].</p>Fórmula:C14H12O4Forma y color:SolidPeso molecular:244.24U92016A hydrochloride
CAS:<p>U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.</p>Fórmula:C19H26ClN3Forma y color:SolidPeso molecular:331.89Carlina oxide
CAS:<p>Carlina oxide is both an AChE inhibitor and an antioxidant, effective in eliminating mosquito larvae (LC50=1.39 μg/mL). Furthermore, Carlina oxide exhibits cytotoxicity in vertebrate cells, human dermis, and HCT116 and MDA-MB231 cell lines.</p>Fórmula:C13H10OForma y color:SolidPeso molecular:182.22ZK 93426 hydrochloride
CAS:<p>benzodiazepine receptor antagonist,competitive</p>Fórmula:C18H21ClN2O3Pureza:98%Forma y color:SolidPeso molecular:348.82Amyloid-β-IN-3
CAS:<p>Amyloid-β-IN-3 (EX.113) is a selective inhibitor of γ-secretase. It demonstrates inhibitory activity on Aβ42 secretion in H4 cells, with an EC50 value of 148 nM. By modulating the catalytic activity of γ-secretase, Amyloid-β-IN-3 decreases Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. It holds potential for Alzheimer's disease (AD) research.</p>Fórmula:C22H21F2N3O2Forma y color:SolidPeso molecular:397.42AChE/BChE-IN-19
CAS:<p>AChE/BChE-IN-19 (compound 12) is a nicotinic hydrazine derivative that acts as an inhibitor of AChE (IC50=21.45 nM) and BChE (IC50=18.42 nM), and it is applicable in Alzheimer's disease research.</p>Fórmula:C26H22N4O3Peso molecular:438.48(9R)-RO7185876
CAS:<p>(9R)-RO7185876 (Compound example 16) is a γ-secretase inhibitor. It reduces the secretion of Αβ42. This compound can be employed in the research of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, multi-infarct dementia, senile dementia, or Down syndrome.</p>Fórmula:C25H28F3N7Forma y color:SolidPeso molecular:483.532Beloxepin
CAS:<p>Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.</p>Fórmula:C19H21NO2Pureza:98%Forma y color:SolidPeso molecular:295.38SZ1676
CAS:<p>SZ1676 is a derivative of SZ1677, which is an agent of neuromuscular blocking.</p>Fórmula:C37H59BrN2O6Pureza:98%Forma y color:SolidPeso molecular:707.78(S)-Norfluoxetine
CAS:<p>(S)-Norfluoxetine, the S enantiomer of Norfluoxetine, functions as a selective serotonin reuptake inhibitor. It enhances allopregnanolone levels and reduces aggression in socially isolated mice.</p>Fórmula:C16H16F3NOForma y color:SolidPeso molecular:295.3CaMKK2-IN-1
CAS:<p>CaMKK2-IN-1 is a selective and potent inhibitor of CaMKK2, exhibiting an IC50 of 7 nM.</p>Fórmula:C22H22N2O3Peso molecular:362.42AChE-IN-47
CAS:<p>AChE-IN-47 (compound g17) is an acetylcholinesterase (AChE) inhibitor with an IC50 of 0.24 μM. It prevents the self-aggregation of β-amyloid peptides and exhibits neuroprotective properties by effectively reducing the accumulation of intracellular reactive oxygen species (ROS).</p>Fórmula:C20H17F3N4O4SPeso molecular:466.43TP003
CAS:<p>TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.</p>Fórmula:C23H16F3N3OPureza:99.17%Forma y color:SolidPeso molecular:407.39AGH-107
CAS:<p>AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.</p>Fórmula:C13H12IN3Forma y color:SolidPeso molecular:337.16BPN-15606 besylate
<p>BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).</p>Fórmula:C29H29FN6O4SForma y color:SolidPeso molecular:576.64HDAC6-IN-9
CAS:<p>HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.</p>Fórmula:C19H16N2O3Pureza:98.84%Forma y color:SolidPeso molecular:320.34Aβ42 agonist-1
CAS:<p>Aβ42 agonist-1 is a small molecule compound with anti-cancer activity and NF-κB inhibitory properties, inducing Aβ42 aggregation.</p>Fórmula:C15H11NO2Pureza:99.77%Forma y color:SolidPeso molecular:237.25SB 243213 dihydrochloride
CAS:<p>SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for</p>Fórmula:C22H21Cl2F3N4O2Pureza:98%Forma y color:SolidPeso molecular:501.33DL-Thyroxine
CAS:<p>DL-Thyroxine is a thyroid hormone that acts as a monoamine oxidase (monoamine oxidase) inhibitor.</p>Fórmula:C15H11I4NO4Forma y color:SolidPeso molecular:776.87γ-secretase modulator 6
CAS:<p>Gamma-secretase modulator 6 (Example 50) is a gamma-secretase modulator. It inhibits Aβ42 secretion in HEK cell lines stably expressing APP (Aβ amyloid precursor protein) with a pIC50 of 8.1. This compound is applicable in Alzheimer's disease research.</p>Fórmula:C25H26N6O2Forma y color:SolidPeso molecular:442.513AChE/Aβ-IN-5
CAS:<p>Compound AV-2, also known as AChE/Aβ-IN-5, is a bifunctional inhibitor that acts on AChE and auto-induced Aβ (Amyloid-β) aggregation. This compound has demonstrated significant efficacy in mitigating cognitive impairment in mice induced by scopolamine and Aβ [1].</p>Fórmula:C25H24N4Forma y color:SolidPeso molecular:380.48AChE-IN-63
CAS:<p>AChE-IN-63 (Compound 5AD) serves as a selective inhibitor of hAChE, exhibiting an IC 50 value of 0.103 μM. Moreover, it inhibits hBChE and hBACE-1 with IC 50 values of 10 μM and 1.342 μM, respectively. AChE-IN-63 is effective in inhibiting Aβ aggregation and preventing the formation and deposition of Aβ1-42. It can effectively penetrate the blood-brain barrier and is orally bioavailable. This compound is primarily utilized in research related to Alzheimer's disease [1].</p>Fórmula:C18H19N5OForma y color:SolidPeso molecular:321.38LY 541850
CAS:<p>LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human</p>Fórmula:C9H13NO4Pureza:98%Forma y color:SolidPeso molecular:199.2BMS-901715
CAS:<p>BMS-901715 is an effective and selective inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50: 3.3 nM).</p>Fórmula:C22H28N10OPureza:98%Forma y color:SolidPeso molecular:448.52VU6016235
CAS:<p>VU6016235 is a structurally unique, orally available, and highly selective tricyclic M4 muscarinic acetylcholine receptor positive allosteric modulator.</p>Fórmula:C21H22N4OSForma y color:SolidPeso molecular:378.49K203
<p>K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.</p>Fórmula:C16H18Br2N4O2Forma y color:SolidPeso molecular:458.15AChE-IN-24
<p>AChE-IN-24: Strong AChE blocker, crosses blood-brain barrier, IC50=0.053 μM, useful for AD research.</p>Fórmula:C22H30N2O4S2Forma y color:SolidPeso molecular:450.61CVN636
CAS:<p>CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human</p>Fórmula:C19H20FNO4SForma y color:SolidPeso molecular:377.43Tipindole
CAS:<p>Tipindole is a serotonin antagonist utilized in research related to depression.</p>Fórmula:C16H20N2O2SForma y color:SolidPeso molecular:304.41YNT-3708
CAS:<p>YNT-3708 is an orexin receptor (OXR) agonist, exhibiting EC50 values of 14.6 nM for OX1R and 277 nM for OX2R.</p>Fórmula:C35H36N4O6SForma y color:SolidPeso molecular:640.749Metoquizine
CAS:<p>Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.</p>Fórmula:C22H27N5OPureza:98%Forma y color:SolidPeso molecular:377.48DL-AP5 lithium
CAS:<p>DL-AP5 (2-APV) lithium is a competitive antagonist of the NMDA (N-Methyl-D-aspartate) receptor. It exhibits notable analgesic activity and specifically blocks channels in the rabbit retina.</p>Fórmula:C5H11LiNO5PForma y color:SolidPeso molecular:203.06BF-168
CAS:<p>BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).</p>Fórmula:C18H17FN2O2Forma y color:SolidPeso molecular:312.34PF-06751979
CAS:<p>PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).</p>Fórmula:C18H19F2N5O3S2Pureza:98%Forma y color:SolidPeso molecular:455.5LB-102
CAS:<p>LB-102 is an orally active inhibitor of dopamine D2, D3, and serotonin 5-HT7 receptors, utilized in the study of schizophrenia and other psychiatric disorders.</p>Fórmula:C18H29N3O4SForma y color:SolidPeso molecular:383.51CaMKIIα-IN-1
<p>CaMKIIα-IN-1 (Compound 4d) is an orally active inhibitor of Ca 2+ /calmodulin-dependent protein kinase II α (CaMKIIα) with a Kd of 219 nM for CaMKIIα WT hub.</p>Fórmula:C14H11ClO4Forma y color:SolidPeso molecular:278.69MAO-B-IN-42
CAS:<p>MAO-B-IN-42 (Compound 4f) is a selective and reversible monoamine oxidase-B (MAO-B) inhibitor, with an IC50 value of 0.184 μM. By blocking the oxidative deamination of monoamines catalyzed by MAO-B, it helps maintain neurotransmitter levels. MAO-B-IN-42 shows potential for research into Parkinson's disease.</p>Fórmula:C19H12FNO2Forma y color:SolidPeso molecular:305.302Pomaglumetad methionil
CAS:<p>Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.</p>Fórmula:C12H20N2O8S2Pureza:98%Forma y color:SolidPeso molecular:384.43MADAM
CAS:<p>MADAM demonstrates high affinity and selectivity for 5-HTT, with a Ki value of 1.6 nM. It is utilized as a PET radiotracer for visualizing serotonin transporters.</p>Fórmula:C16H20N2SForma y color:SolidPeso molecular:272.408Gabaculine HCl
CAS:<p>Gabaculine, an irreversible GABA-T inhibitor (Ki: 2.9 μM), impacts plastid development and affects DPOR/GluTR levels.</p>Fórmula:C7H10ClNO2Forma y color:SolidPeso molecular:175.61Rodatristat
CAS:<p>Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).</p>Fórmula:C27H27ClF3N5O3Pureza:98%Forma y color:SolidPeso molecular:561.98GABA-IN-4
CAS:<p>GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.</p>Fórmula:C17H13ClN2O2Forma y color:SolidPeso molecular:312.75SGE-516
CAS:<p>SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.</p>Fórmula:C23H35N3O2Pureza:98%Forma y color:SolidPeso molecular:385.54LRRK2-IN-16
CAS:<p>LRRK2-IN-16 (compound 25) is an inhibitor of the LRRK2 kinase with an IC50 value of less than 5 μM. It is applicable for research in neurodegenerative and autoimmune diseases.</p>Fórmula:C18H19N5OSForma y color:SolidPeso molecular:353.441S-8510 phosphate
CAS:<p>S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).</p>Fórmula:C12H13N4O6PPureza:98%Forma y color:SolidPeso molecular:340.235-HT2A/5-HT2C inverse agonist 1
CAS:<p>5-HT2A/5-HT2C inverse agonist 1 serves as a dual and potent inverse agonist for the 5-HT2A and 5-HT2C receptors, with hERG inhibition properties that mitigate cardiovascular risks. Demonstrating significant antipsychotic efficacy in the MK-801-induced mouse model, this compound holds potential for psychosis research.</p>Fórmula:C24H35N5O2Forma y color:SolidPeso molecular:425.57MAO-A/SERT-IN-1
CAS:<p>MAO-A/SERT-IN-1 acts as an inhibitor for both MAO-A and the serotonin transporter (SERT). It decreases the SERT-mediated reuptake of 5-HT and demonstrates neuroprotective properties in cellular inhibition models. Additionally, this compound has shown to alleviate depressive behaviors in both zebrafish and mice.</p>Fórmula:C19H14N2O5Forma y color:SolidPeso molecular:350.32Antioxidant agent-8
<p>Antioxidant agent-8, an oral Aβ 1-42 inhibitor, reduces fibril aggregation & promotes disaggregation; it's neuroprotective & BBB permeable.</p>Fórmula:C13H12O5Forma y color:SolidPeso molecular:248.23VA012
CAS:<p>VA012 (compound 11) acts as a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. It has been shown to reduce food intake and prevent weight gain during subchronic administration without causing central nervous system-related discomfort. VA012 is applicable in obesity research.</p>Fórmula:C21H19N3Forma y color:SolidPeso molecular:313.40Monoamine Oxidase B inhibitor 1
<p>Potent, selective MAO-B inhibitor; reversible; oral; crosses BBB; IC50=0.02 nM; potential for Parkinson's research.</p>Fórmula:C18H15FO3Forma y color:SolidPeso molecular:298.31RTIOXA-43
CAS:<p>RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.</p>Fórmula:C37H37N5O5SPureza:99.17%Forma y color:SolidPeso molecular:663.79THRX-194556
CAS:<p>THRX-194556 is an agonist of the 5-HT4 receptor. It is applicable in the study of gastrointestinal functional disorders and Alzheimer's disease.</p>Fórmula:C28H41N5O5SForma y color:SolidPeso molecular:559.721Aβ42-IN-1
CAS:<p>Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).</p>Fórmula:C29H27ClN4O2Pureza:98%Forma y color:SolidPeso molecular:499LP 12 hydrochloride hydrate
<p>LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.</p>Fórmula:C32H39N3O·HCl·xH2OForma y color:SolidMAO-B-IN-34
CAS:<p>MAO-B-IN-34 (compound 3d) is an inhibitor of monoamine oxidase B.</p>Fórmula:C15H9Cl2NO3Forma y color:SolidPeso molecular:322.148 Hydroxy PIPAT oxalate
CAS:<p>8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.</p>Fórmula:C18H24INO5Forma y color:SolidPeso molecular:461.29Zanapezil fumarate
CAS:<p>Zanapezil is an acetylcholinesterase (AChE) inhibitor. Zanapezil increases choline acetyltransferase activity in cultured rat septal cholinergic neurons.</p>Fórmula:C29H36N2O5Forma y color:SolidPeso molecular:492.61Dual AChE-MAO B-IN-1
<p>Dual AChE-MAO B-IN-1: orally active CNS-permeable, safe, stable neuroprotective agent; AChE IC50=550 nM, MAO-B IC50=8.2 nM.</p>Fórmula:C23H25F2NO4Forma y color:SolidPeso molecular:417.455-IAI hydrochloride
CAS:<p>5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.</p>Fórmula:C9H11ClINForma y color:SolidPeso molecular:295.548Remlifanserin
CAS:<p>Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).</p>Fórmula:C24H29F2N3O2Forma y color:SolidPeso molecular:429.50Poskine
CAS:<p>Poskine is an anticholinergic and central nervous system depressant. It is utilized in research related to Parkinson's disease and motion sickness.</p>Fórmula:C20H25NO5Forma y color:SolidPeso molecular:359.42Serotonin maleate
CAS:<p>Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.</p>Fórmula:C14H16N2O5Forma y color:SolidPeso molecular:292.287RO-1-5237
CAS:<p>RO-1-5237, a cholinergic compound and a metabolic product of Pyridostigmine Bromide, is utilized in research for myasthenia gravis.</p>Fórmula:C6H8BrNOForma y color:SolidPeso molecular:190.04Aβ-IN-2
<p>Aβ-IN-2 is a peptide inhibitor of Aβ1-42.</p>Fórmula:C37H51NOForma y color:SolidPeso molecular:525.81Dihydro-β-erythroidine
CAS:<p>Dihydro-β-erythroidine, a competitive nicotinic receptor antagonist, effectively blocks the discriminative stimulus properties and inhibits the anxiolytic</p>Fórmula:C16H21NO3Forma y color:SolidPeso molecular:275.34LRRK2-IN-4
CAS:<p>LRRK2-IN-4: Potent, selective LRRK2 inhibitor, oral, BBB-penetrating, IC50=2.6 nM, potential for Parkinson's.</p>Fórmula:C25H29ClF2N6O2Forma y color:SolidPeso molecular:518.99Revexepride
CAS:<p>Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.</p>Fórmula:C21H32ClN3O4Pureza:98%Forma y color:SolidPeso molecular:425.95DSP-1053 benzenesulfonate
CAS:<p>DSP-1053: Benzylpiperidine-based, potent SERT inhibitor (Ki=1.02nM), partial 5-HT1A receptor agonist (Ki=5.05nM), antidepressant.</p>Fórmula:C32H38BrNO7SForma y color:SolidPeso molecular:660.62Tiprenolol hydrochloride
CAS:<p>Tiprenolol hydrochloride is a β-adrenoceptor (β-adrenoceptor) antagonist. This compound is effective in eliminating ventricular arrhythmias in dogs caused by intravenous administration of adrenaline, following inhalation of halothane.</p>Fórmula:C13H22ClNO2SForma y color:SolidPeso molecular:291.84AChE-IN-79
<p>AChE-IN-79 (compound 3i) is an acetylcholinesterase inhibitor with an IC50 of 2.7 µM, suitable for studies related to Alzheimer's disease.</p>Fórmula:C29H27NO6SForma y color:SolidPeso molecular:517.59MAO-B-IN-10
<p>MAO-B-IN-10: Potent, selective MAO-B inhibitor; crosses blood-brain barrier; IC50 5.3 μM; reduces Aβ aggregation 58.2%, disaggregates 43.3%.</p>Fórmula:C23H26N2O4Forma y color:SolidPeso molecular:394.46BACE1-IN-5
CAS:<p>BACE1-IN-5 inhibits BACE1 (IC50: 9.1 nM) & Aβ production (IC50: 0.82 nM), enhances hERG inhibition & P-gp efflux.</p>Fórmula:C18H16F5N5O2SPureza:98%Forma y color:SolidPeso molecular:461.41Monoamine Oxidase B inhibitor 2
<p>MAO-B inhibitor 2: potent, reversible, oral, selective (IC50=1.33 nM), BBB-penetrant, with anti-oxidant and anti-inflammatory effects for Parkinson's study.</p>Fórmula:C19H19FO3Forma y color:SolidPeso molecular:314.35AChE/BChE-IN-1
<p>AChE/BChE-IN-1: dual AChE/BChE inhibitor, IC50 of 1.06 nM/7.3 nM, crosses blood-brain barrier, with antioxidant properties for Alzheimer's research.</p>Fórmula:C32H35ClN6O3Forma y color:SolidPeso molecular:587.11Tuclazepam
CAS:<p>Tuclazepam (KC 1956) is a derivative of the benzodiazepine class of drugs, exhibiting anti-anxiety and sedative properties.</p>Fórmula:C17H16Cl2N2OForma y color:SolidPeso molecular:335.23LY367385 hydrochloride
CAS:<p>LY367385 hydrochloride: selective mGluR1a antagonist, IC50 = 8.8 μM, neuroprotective, anticonvulsant, antiepileptic.</p>Fórmula:C10H12ClNO4Forma y color:SolidPeso molecular:245.66Etoperidone
CAS:<p>Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).</p>Fórmula:C19H28ClN5OForma y color:SolidPeso molecular:377.91AM-6494
CAS:<p>AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM).</p>Fórmula:C22H21F2N5O3SPureza:98%Forma y color:SolidPeso molecular:473.5VU6007496
CAS:<p>VU6007496 is a highly selective and CNS-penetrating M1 positive allosteric modulator (PAM) that exhibits good pharmacokinetics (PK).</p>Fórmula:C25H27N5O2Forma y color:SolidPeso molecular:429.51SB 243213 hydrochloride
CAS:<p>SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).It</p>Fórmula:C22H20ClF3N4O2Pureza:98%Forma y color:SolidPeso molecular:464.87AChE/BChE-IN-3 hydrochloride
<p>AChE/BChE-IN-3 (BMC-1) HCl is a dual inhibitor with IC50s: eqBChE 0.383 μM, elAChE 6.08 μM.</p>Fórmula:C15H25ClN2O3Forma y color:SolidPeso molecular:316.82MAO-B-IN-5
CAS:<p>MAO-B-IN-5: potent, selective oral MAO-B inhibitor, IC50=0.204μM, potential for Parkinson's research.</p>Fórmula:C19H21FN2O2Pureza:97.68%Forma y color:SolidPeso molecular:328.38D3/5-HT receptor modulator-1
CAS:<p>D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.</p>Fórmula:C24H29N3O2Forma y color:SolidPeso molecular:391.506AChE-IN-22
<p>AChE-IN-22 (10q) selectively inhibits AChE (IC50: 0.88 μM), less on BuChE (IC50: 10 μM), targets CAS and PAS, useful in Alzheimer's research.</p>Fórmula:C21H20N4O5SForma y color:SolidPeso molecular:440.47Azotomycin
CAS:<p>Azotomycin is an antagonist of L-glutamine and may be used as an immunosuppressant.</p>Fórmula:C17H23N7O8Pureza:98%Forma y color:SolidPeso molecular:453.41Sulamserod hydrochloride
CAS:<p>Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.</p>Fórmula:C19H29Cl2N3O5SForma y color:SolidPeso molecular:482.422,6-Dimethoxybenzylamine hydrochloride
CAS:<p>2,6-Dimethoxybenzylamine hydrochloride (Compound 5) exhibits reversible inhibitory activity against copper amine oxidase (CAO) and inhibits benzylamine oxidase (BAO) and monoamine oxidase B (MAO B) with IC50 values of 120 μM and 190 μM, respectively.</p>Fórmula:C9H14ClNO2Forma y color:SolidPeso molecular:203.666AAZ-A 154
CAS:<p>AAZ-A 154 is a selective, competitive, and non-hallucinogenic antagonist of the 5-HT2AR. It promotes neuronal growth in rodents and results in lasting beneficial behavioral effects.</p>Fórmula:C14H20N2OForma y color:SolidPeso molecular:232.32LRRK2-IN-6
<p>LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).</p>Fórmula:C23H24F2N4O2SForma y color:SolidPeso molecular:458.525-HT1A antagonist 1
<p>Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.</p>Fórmula:C23H29ClN6O2Forma y color:SolidPeso molecular:456.97PTCA
CAS:<p>PTCA is a potent ligand for Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα), with a pKi value of 7.2.</p>Fórmula:C10H5Cl2NO2SForma y color:SolidPeso molecular:274.123Tebideutorexant
CAS:<p>Tebideutorexant, an orexin-1 receptor antagonist, shows anti-panic effects in rodents and humans, providing a tool for stress response and psychiatric research.</p>Fórmula:C23H16D2F4N4O2Pureza:98.89%Forma y color:SolidPeso molecular:460.42LY593093
CAS:<p>LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.</p>Fórmula:C32H30FN3O2Pureza:98%Forma y color:SolidPeso molecular:507.6CB2R/5-HT1AR agonist 1
CAS:<p>Compound 2o, also known as CB2R/5-HT1AR agonist 1, serves as a partial orally active agonist for the CB2 receptor (EC50 = 479.6 nM) and a full agonist for the 5-HT1A receptor (EC50 = 2.7 μM). This compound demonstrates both anti-anxiety and anti-depressive effects and has favorable pharmacokinetic properties [1].</p>Fórmula:C24H33NO3Forma y color:SolidPeso molecular:383.522002-G12
CAS:<p>2002-G12 (compound 5a) is an Aβ42 inhibitor that can reduce Aβ42 toxicity by 76%. It is applicable in Alzheimer's research.</p>Fórmula:C20H16N6Forma y color:SolidPeso molecular:340.381Pareptide monohydrochloride
CAS:<p>Pareptide monohydrochloride is a metabolically stable analog of melatonin inhibitor (MIF).</p>Fórmula:C14H27ClN4O3Pureza:98%Forma y color:SolidPeso molecular:334.84PF-06648671
CAS:<p>PF-06648671 is a γ-secretase modulator for the treatment of neurodegenerative and/or neurological disorders.</p>Fórmula:C25H23ClF4N4O3Pureza:98%Forma y color:SolidPeso molecular:538.92R-96544 hydrochloride
CAS:<p>5-HT2 receptor antagonist</p>Fórmula:C22H29NO3Pureza:98%Forma y color:SolidPeso molecular:355.47BChE-IN-5
<p>BChE-IN-5: potent, selective BChE inhibitor (IC50: 2.8 nM), more effective on hBChE, potential in Alzheimer's research.</p>Fórmula:C30H42N4OForma y color:SolidPeso molecular:474.68Glutaminyl Cyclase Inhibitor 3
CAS:<p>Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.</p>Fórmula:C24H32N6O2SPureza:98%Forma y color:SolidPeso molecular:468.61
