Neurociencia

<p>Seganserin, a 5-HT2 antagonist, negates fluoxetine and quipazine's effects on hyperphagia, depression, and pain.</p>

<p>(Iso)-BMT-124110 Formate has an inhibitory effect on the protein serine/threonine kinase AAK, and is used in the treatment of Parkinson's disease, schizophrenia</p>

<p>Etifoxine hydrochloride (HOE 36-801 hydrochloride) is an anxiolytic and anticonvulsant drug.</p>

<p>3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) (TMCA) is one of the constituents of Polygalae Radix and may exert anti-seizure activity by acting at the</p>

<p>Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent.</p>

<p>Tolfenamic Acid (GEA 6414) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.</p>

<p>Aripiprazole (OPC-14597) is a piperazine/quinolone antipsychotic, partial agonist at 5-HT1A/D2, and antagonist at 5-HT2A.</p>

<p>Nebracetam HCl (WEB 1881 FU) is an M1-muscarinic agonist nootropic, increasing intracellular Ca2+ with an EC50 of 1.59 mM.</p>

<p>SSR 180 is a potent and subtype-selective α7 agonist with applications in the study of Alzheimer;s disease and schizophrenia.</p>

<p>This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Mouse BNP protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse BNP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse BNP in the samples is then determined by comparing the OD of the samples to the standard curve.</p>

<p>This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Pig GH protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Pig GH. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Pig GH in the samples is then determined by comparing the OD of the samples to the standard curve.</p>

<p>Dofequidar fumarate (MS-209)(MS-209 fumarate), a quinoline-based compound administered orally, is known for counteracting multidrug resistance (MDR) through the</p>

<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>

<p>Sabcomeline HCl is an M1 receptor agonist that can be used to study Alzheimer's disease.</p>

<p>The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PGD2S. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PGD2S. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human PGD2S, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human PGD2S in the samples is then determined by comparing the OD of the samples to the standard curve.</p>

<p>Bismuth Subsalicylate, Pepto-Bismol's active ingredient, treats nausea, heartburn, indigestion, diarrhea, and stomach upset.</p>

<p>Y-33075 dihydrochloride is a selective inhibitor of ROCK(IC50 of 3.6 nM).</p>

<p>Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).</p>

<p>Vecuronium bromide (ORG NC 45) is a synthetic, intermediate-acting mono-quaternary steroid and non-depolarizing neuromuscular blocking agent, with muscle</p>

<p>Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain.</p>

<p>Isoxicam (Isoxicamum) is a non-steroidal anti-inflammatory drug that is not marketed in the United States.</p>

<p>Broflanilide metabolite desmethyl-broflanilide blocks GABA receptor in dieldrin-resistant insects, inhibiting S. litura at IC50 1.3 nM.</p>

<p>Aceclofenac (Preservex) is a non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties.</p>

<p>Encequidar mesylate (HM30181A mesylate) is a competitive P-glycoprotein inhibitor.</p>

<p>GTS-21 dihydrochloride (DMBX-anabaseine) is a nAChRs agonist. nAChRs are neuron receptor proteins that activated by the binding of the neurotransmitter ACh.</p>

<p>AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).</p>

<p>V-11-0711 HCl is a selective and highly effective choline kinase α (ChoKα) inhibitor that inhibits the catalytic activity of Chk.</p>

<p>Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.</p>

<p>Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptive</p>

<p>nAChR agonist 1 (DUN71755) is a brain-permeable and orally efficacious positive allosteric α7 nicotinic acetylcholine receptor (α7 nAChR)modulator.</p>