Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(940 productos)
- ACK(1 productos)
- AChR(574 productos)
- ATP Citrato Liasa(16 productos)
- Receptor adrenérgico(2.942 productos)
- BACE(36 productos)
- Beta amiloide(204 productos)
- CAMK(68 productos)
- Inhibidores de ciclooxigenasa (COX)(562 productos)
- Receptor de dopamina(407 productos)
- Receptor GABA(336 productos)
- Gamma-secretasa(59 productos)
- GluR(255 productos)
- GlyT(24 productos)
- Receptor de histamina(358 productos)
- LRRK2(33 productos)
- Receptor de melatonina(24 productos)
- NMDAR(28 productos)
- Receptor de OX(40 productos)
- Receptor de opioides(296 productos)
Mostrar 12 subcategorías más
Se han encontrado 5400 productos de "Neurociencia"
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Zamifenacin fumarate
CAS:<p>Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.</p>Fórmula:C31H33NO7Pureza:99.88%Forma y color:SolidPeso molecular:531.6GR 127935 hydrochloride
CAS:<p>5-HT1B/1D receptor antagonist</p>Fórmula:C29H32ClN5O3Pureza:98%Forma y color:SolidPeso molecular:534.05PTAC oxalate
CAS:<p>muscarinic receptor ligand</p>Fórmula:C14H21N3O4S2Pureza:98%Forma y color:SolidPeso molecular:359.465-HT3-In-1
CAS:<p>5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.</p>Fórmula:C16H21ClN4O3Pureza:98%Forma y color:SolidPeso molecular:352.82mAChR antagonist 1
CAS:<p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>Fórmula:C19H22N2O2Forma y color:SolidPeso molecular:310.39LY108742
CAS:<p>LY108742 is an antagonist of 5-HT2.</p>Fórmula:C21H28N2O3Pureza:98%Forma y color:SolidPeso molecular:356.46TPA 023
CAS:<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Fórmula:C20H22FN7OPureza:99.75%Forma y color:SolidPeso molecular:395.436,2'-Dihydroxyflavone
CAS:<p>6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.</p>Fórmula:C15H10O4Pureza:99.44% - 99.67%Forma y color:SolidPeso molecular:254.24MIN-117
CAS:<p>MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.</p>Fórmula:C25H26Cl3N3O4Pureza:98%Forma y color:SolidPeso molecular:538.855-HT3 antagonist 1
CAS:<p>5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.</p>Fórmula:C22H27N5OPureza:98%Forma y color:SolidPeso molecular:377.48VU0453595
CAS:<p>VU0453595 is a M1 positive allosteric modulator (PAM).</p>Fórmula:C18H15FN4OPureza:99.91%Forma y color:SolidPeso molecular:322.34Yhhu-3792 hydrochloride
CAS:<p>Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].</p>Fórmula:C24H25ClN4O2Forma y color:SolidPeso molecular:436.93KBR 2822
CAS:<p>KBR 2822 is an inhibitor of esterase.</p>Fórmula:C9H15ClF3O3PSPureza:98%Forma y color:SolidPeso molecular:326.7Facinicline hydrochloride
CAS:<p>Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).</p>Fórmula:C15H19ClN4OPureza:98.70%Forma y color:SolidPeso molecular:306.79VU0360172
CAS:<p>VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).</p>Fórmula:C18H15FN2OPureza:99.56%Forma y color:SolidPeso molecular:294.32DU-125530
CAS:<p>DU-125530 is a 5-HT1A receptor antagonist.</p>Fórmula:C23H26ClN3O5SForma y color:SolidPeso molecular:491.99LY3202626
CAS:<p>LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.</p>Fórmula:C22H20F2N8O2SPureza:98%Forma y color:SolidPeso molecular:498.51GYKI-46903 HCl
CAS:<p>GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.</p>Fórmula:C17H21ClFNO2Forma y color:SolidPeso molecular:325.81MAO-B-IN-1
CAS:<p>MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.</p>Fórmula:C16H14F3N3O2SPureza:98%Forma y color:SolidPeso molecular:369.36RAGE/SERT-IN-1
CAS:<p>RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM and</p>Fórmula:C38H41ClN4OSForma y color:SolidPeso molecular:637.28Cyclophostin
CAS:<p>Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).</p>Fórmula:C8H11O6PPureza:98%Forma y color:SolidPeso molecular:234.14PNU109291
CAS:<p>PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.</p>Fórmula:C24H31N3O3Pureza:98%Forma y color:SolidPeso molecular:409.52BMS-932481
CAS:<p>BMS-932481 is a γ-secretase modulator.</p>Fórmula:C24H24FN7OForma y color:SolidPeso molecular:445.49CGP 54626 hydrochloride
CAS:<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Fórmula:C18H29Cl3NO3PPureza:98%Forma y color:SolidPeso molecular:444.76Mesembrine
CAS:<p>Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).</p>Fórmula:C17H23NO3Forma y color:SolidPeso molecular:289.37(2R,4R)-APDC
CAS:<p>(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.</p>Fórmula:C6H10N2O4Pureza:98%Forma y color:SolidPeso molecular:174.15Naspm trihydrochloride
CAS:<p>Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride) is a synthetic analogue of Joro spider toxin and is an antagonist of calcium permeable AMPA</p>Fórmula:C22H37Cl3N4OPureza:99.75%Forma y color:SolidPeso molecular:479.91UNC9994 hydrochloride
CAS:<p>UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.</p>Fórmula:C21H23Cl3N2OSForma y color:SolidPeso molecular:457.84Anti-amyloid agent-1
CAS:<p>Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].</p>Fórmula:C21H17F3N2O3Forma y color:SolidPeso molecular:402.37Indeloxazine hydrochloride
CAS:<p>Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.</p>Fórmula:C14H18ClNO2Pureza:98%Forma y color:SolidPeso molecular:267.75β-Secretase Inhibitor IV
CAS:<p>β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).</p>Fórmula:C31H38N4O5SPureza:98%Forma y color:SolidPeso molecular:578.72GSM-1
CAS:<p>GSM-1 is a modulator of γ-Secretase.</p>Fórmula:C26H31ClF3NO2Forma y color:SolidPeso molecular:481.98BACE-1 inhibitor 1
CAS:<p>BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).</p>Fórmula:C17H14BrF3N4O2Pureza:98%Forma y color:SolidPeso molecular:443.22Aβ/tau aggregation-IN-3
CAS:<p>Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functional</p>Fórmula:C23H22N4O3Forma y color:SolidPeso molecular:402.45LY-426965
CAS:<p>LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.</p>Fórmula:C28H38N2O2Forma y color:SolidPeso molecular:434.61Physostigmine hemisulfate
CAS:<p>cholinesterase inhibitor</p>Fórmula:C15H21N302H204SPureza:98%Forma y color:SolidPeso molecular:324.39CGP36216 hydrochloride
CAS:<p>CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].</p>Fórmula:C5H15ClNO2PForma y color:SolidPeso molecular:187.6Tiotropium Bromide hydrate
CAS:<p>Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.</p>Fórmula:C19H24BrNO5S2Pureza:98.44% - 99.41%Forma y color:SolidPeso molecular:490.43R-96544
CAS:<p>R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].</p>Fórmula:C22H30ClNO3Forma y color:SolidPeso molecular:391.93Nemonapride
CAS:<p>Nemonapride is a dopamine D2-like receptor antagonist.</p>Fórmula:C21H26ClN3O2Pureza:98%Forma y color:SolidPeso molecular:387.9AAK1-IN-5
CAS:<p>AAK1-IN-5: Potent, selective AAK1 inhibitor; CNS-penetrant; oral; IC50: 1.2 nM; Ki: 0.05 nM; cell IC50: 0.5 nM. Useful in neuropathic pain research.</p>Fórmula:C19H23F4N3OForma y color:SolidPeso molecular:385.4GABAA receptor agent 2 TFA
CAS:<p>Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.</p>Fórmula:C22H22F3N3O3Forma y color:SolidPeso molecular:433.42NO-711ME
CAS:<p>NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.</p>Fórmula:C22H24N2O3Pureza:99.54%Forma y color:SolidPeso molecular:364.44VU6005649
CAS:<p>VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).</p>Fórmula:C16H12F5N3OPureza:99.87%Forma y color:SolidPeso molecular:357.28mGAT-IN-1
CAS:<p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>Fórmula:C28H34ClN3O2S2Forma y color:SolidPeso molecular:544.17BChE-IN-20
CAS:<p>BChE-IN-20 (compound 7c) is a potent, selective inhibitor of BChE, demonstrating IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE.</p>Fórmula:C27H39N5O2Forma y color:SolidPeso molecular:465.635-HT2 agonist-1
CAS:<p>Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.</p>Fórmula:C19H23ClN2O2Pureza:98%Forma y color:SolidPeso molecular:346.85NAS181
CAS:<p>rat 5-HT1B receptor antagonist</p>Fórmula:C21H34N2O10S2Pureza:98%Forma y color:SolidPeso molecular:538.63QR-0217
CAS:<p>QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.</p>Fórmula:C19H13NO3Forma y color:SolidPeso molecular:303.31Cimicoxib
CAS:<p>Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.</p>Fórmula:C16H13ClFN3O3SPureza:98.22%Forma y color:SolidPeso molecular:381.81
