Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(940 productos)
- ACK(1 productos)
- AChR(574 productos)
- ATP Citrato Liasa(16 productos)
- Receptor adrenérgico(2.942 productos)
- BACE(36 productos)
- Beta amiloide(204 productos)
- CAMK(68 productos)
- Inhibidores de ciclooxigenasa (COX)(562 productos)
- Receptor de dopamina(407 productos)
- Receptor GABA(336 productos)
- Gamma-secretasa(59 productos)
- GluR(255 productos)
- GlyT(24 productos)
- Receptor de histamina(358 productos)
- LRRK2(33 productos)
- Receptor de melatonina(24 productos)
- NMDAR(28 productos)
- Receptor de OX(40 productos)
- Receptor de opioides(296 productos)
Mostrar 12 subcategorías más
Se han encontrado 5400 productos de "Neurociencia"
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Octahydroaminoacridine succinate
CAS:<p>Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.</p>Fórmula:C17H24N2O4Pureza:99.91%Forma y color:SolidPeso molecular:320.38Cyanopindolol fumarate
CAS:<p>Cyanopindolol fumarate is a 5-HT receptor antagonist [1].</p>Fórmula:C16H21N3O2C4H4O4Forma y color:SolidPeso molecular:345.4CGP36216 hydrochloride
CAS:<p>CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].</p>Fórmula:C5H15ClNO2PForma y color:SolidPeso molecular:187.6BChE-IN-20
CAS:<p>BChE-IN-20 (compound 7c) is a potent, selective inhibitor of BChE, demonstrating IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE.</p>Fórmula:C27H39N5O2Forma y color:SolidPeso molecular:465.63LY320954
CAS:<p>LY320954 is an antagonist of 5-HT2A receptor.</p>Fórmula:C21H26N4O3Pureza:98%Forma y color:SolidPeso molecular:382.46L 663581
CAS:<p>L 663581 is the benzodiazepine receptor partial agonist.</p>Fórmula:C17H16ClN5O2Pureza:98%Forma y color:SolidPeso molecular:357.79QR-0217
CAS:<p>QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.</p>Fórmula:C19H13NO3Forma y color:SolidPeso molecular:303.31MGS-0039
CAS:<p>MGS-0039: Group II mGluR2/3 antagonist, non-serotonergic antidepressant-like effect, AMPA involvement, regulates dopamine in NAc.</p>Fórmula:C15H14Cl2FNO5Pureza:98%Forma y color:SolidPeso molecular:378.18P2X3 antagonist 38
CAS:<p>Compound 38, also known as Compound 4, is a potent, orally active P2X3 antagonist that demonstrates inhibitory activity with IC50 values of 0.132 µM, 0.165 µM,</p>Fórmula:C22H25F3N6O3Pureza:98%Forma y color:SolidPeso molecular:478.47PZ-1190
CAS:<p>PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].</p>Fórmula:C27H30N4O2S2Pureza:98%Forma y color:SolidPeso molecular:506.68Cyclophostin
CAS:<p>Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).</p>Fórmula:C8H11O6PPureza:98%Forma y color:SolidPeso molecular:234.14Naspm trihydrochloride
CAS:<p>Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride) is a synthetic analogue of Joro spider toxin and is an antagonist of calcium permeable AMPA</p>Fórmula:C22H37Cl3N4OPureza:99.75%Forma y color:SolidPeso molecular:479.91VU 0255035
CAS:<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Fórmula:C18H20N6O3S2Pureza:98.09% - 98.1%Forma y color:SolidPeso molecular:432.52BT-GSI
<p>BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.</p>Fórmula:C26H46BrN5O10P2Forma y color:SolidPeso molecular:730.52VU6005649
CAS:<p>VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).</p>Fórmula:C16H12F5N3OPureza:99.87%Forma y color:SolidPeso molecular:357.28NAS181
CAS:<p>rat 5-HT1B receptor antagonist</p>Fórmula:C21H34N2O10S2Pureza:98%Forma y color:SolidPeso molecular:538.63RAGE/SERT-IN-1
CAS:<p>RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM and</p>Fórmula:C38H41ClN4OSForma y color:SolidPeso molecular:637.28Wf-516
CAS:<p>Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant</p>Fórmula:C25H25Cl2N3O4Pureza:98%Forma y color:SolidPeso molecular:502.39BMS-983970
CAS:<p>BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.</p>Fórmula:C26H26F4N4O3Forma y color:SolidPeso molecular:518.5(S)-Renzapride
<p>(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.</p>Fórmula:C16H22ClN3O2Forma y color:SolidPeso molecular:323.82MAO-B-IN-19
CAS:<p>MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].</p>Fórmula:C15H11FO2Pureza:98%Forma y color:SolidPeso molecular:242.25β-Secretase Inhibitor IV
CAS:<p>β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).</p>Fórmula:C31H38N4O5SPureza:98%Forma y color:SolidPeso molecular:578.72MIN-117
CAS:<p>MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.</p>Fórmula:C25H26Cl3N3O4Pureza:98%Forma y color:SolidPeso molecular:538.85Fosthiazate
CAS:<p>Fosthiazate is a broad-spectrum nematicide that combats a range of plant parasitic nematodes such as Meloidogyne spp., Globodera spp., and Pratylenchus spp., by</p>Fórmula:C9H18NO3PS2Pureza:97.78%Forma y color:SolidPeso molecular:283.35VU0360172
CAS:<p>VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).</p>Fórmula:C18H15FN2OPureza:99.56%Forma y color:SolidPeso molecular:294.32PQM130
CAS:<p>PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.</p>Fórmula:C23H27NO4Pureza:98.73%Forma y color:SolidPeso molecular:381.46BACE1-IN-13
CAS:<p>BACE1-IN-13 (Compound 36), an orally active inhibitor of BACE1, exhibits high potency with an IC50 of 2.9 nM and demonstrates greater efficacy in hAβ42 cells (</p>Fórmula:C20H17FN8O2Pureza:98%Forma y color:SolidPeso molecular:420.4DQP-26
CAS:<p>DQP-26, a potent negative allosteric modulator of NMDA receptors (NMDARs), exhibits IC50 values of 0.77 μM for GluN2C and 0.44 μM for GluN2D subunits,</p>Fórmula:C28H21Cl2N3O4Pureza:98%Forma y color:SolidPeso molecular:534.39DU-125530
CAS:<p>DU-125530 is a 5-HT1A receptor antagonist.</p>Fórmula:C23H26ClN3O5SForma y color:SolidPeso molecular:491.99Indeloxazine hydrochloride
CAS:<p>Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.</p>Fórmula:C14H18ClNO2Pureza:98%Forma y color:SolidPeso molecular:267.75NCS-382 sodium
CAS:<p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>Fórmula:C13H13NaO3Pureza:98%Forma y color:SolidPeso molecular:240.23Cimicoxib
CAS:<p>Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.</p>Fórmula:C16H13ClFN3O3SPureza:98.22%Forma y color:SolidPeso molecular:381.815-HT2A&5-HT2C agonist-1
CAS:<p>5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.</p>Fórmula:C14H20N2OPureza:98%Forma y color:SolidPeso molecular:232.32Yhhu-3792 hydrochloride
CAS:<p>Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].</p>Fórmula:C24H25ClN4O2Forma y color:SolidPeso molecular:436.93VU6012962
CAS:<p>VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).</p>Fórmula:C21H19F3N4O4Pureza:99.61% - 99.74%Forma y color:SolidPeso molecular:448.4rel-HDMP 28 hydrochloride
CAS:<p>Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].</p>Fórmula:C18H22ClNO2Forma y color:SolidPeso molecular:319.832-Methyl-5-HT
CAS:<p>2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>Fórmula:C11H14N2OPureza:97.18%Forma y color:SolidPeso molecular:190.24PZ-II-029
CAS:<p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>Fórmula:C18H15N3O3Pureza:99.79%Forma y color:SolidPeso molecular:321.33Thioflosulide
CAS:<p>Thioflosulide (L-745337) is a selective and potent COX2 inhibitor (IC50: 2.3 nM) with anti-inflammatory activity for the study of gastric ulcers.</p>Fórmula:C16H13F2NO3S2Pureza:>99.99%Forma y color:SolidPeso molecular:369.41NP-1815-PX
CAS:<p>NP-1815-PX is a P2X4R antagonist with anti-inflammatory and analgesic properties, inhibiting guinea pig tracheal, and can be used in chronic pain research.</p>Fórmula:C21H13N4NaO3SPureza:97.82% - 99.39%Forma y color:SolidPeso molecular:424.41C3
CAS:<p>C3 functions as a selective inhibitor of monoamine oxidase B (MAO-B; IC50= 0.021 µM), demonstrating preference over monoamine oxidase A (MAO-A; IC50= 26.8 µM). This compound, at dosages of 0.1, 1, and 3 mg/kg, effectively counters MPTP-induced reductions in dopamine levels within the mouse brain.</p>Fórmula:C18H19FN2O2Forma y color:SolidPeso molecular:314.35Brasofensine Maleate
CAS:<p>Brasofensine Maleate inhibits the monoamine re-uptake.</p>Fórmula:C20H24Cl2N2O5Forma y color:SolidPeso molecular:443.32Aβ/tau aggregation-IN-3
CAS:<p>Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functional</p>Fórmula:C23H22N4O3Forma y color:SolidPeso molecular:402.453-Bromocytisine
CAS:<p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>Fórmula:C11H13BrN2OPureza:99.974%Forma y color:SolidPeso molecular:269.14AMG-8718
CAS:<p>AMG-8718, an oral BACE1 blocker (IC50: 0.0007 μM), also inhibits BACE2 (IC50: 0.005 μM), lowering CSF and Aβ40 brain levels.</p>Fórmula:C25H19FN4O3Forma y color:SolidPeso molecular:442.44AAK1-IN-3
CAS:<p>AAK1-IN-3: Brain-penetrant AAK1 inhibitor for neuropathic pain research; IC50=11 nM.</p>Fórmula:C20H20N4Forma y color:SolidPeso molecular:316.4COR659
CAS:<p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>Fórmula:C16H16ClNO3SPureza:99.75%Forma y color:SolidPeso molecular:337.82Lanabecestat camsylate
CAS:<p>Lanabecestat camsylate is used as a BACE1 Inhibitor.</p>Fórmula:C36H44N4O5SPureza:98%Forma y color:SolidPeso molecular:644.83VU0029251
CAS:<p>VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.</p>Fórmula:C10H11N3S2Forma y color:SolidPeso molecular:237.34GMA-839
CAS:<p>GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.</p>Fórmula:C21H31F3O3Pureza:98%Forma y color:SolidPeso molecular:388.46
