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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5400 productos de "Neurociencia"

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  • Methalthiazide

    CAS:
    <p>Methalthiazide enhances the activity of natural agonists of AMPA receptors and can be utilized in schizophrenia research.</p>
    Fórmula:C12H16ClN3O4S3
    Forma y color:Solid
    Peso molecular:397.92
  • Syntide 2 TFA


    <p>Syntide 2 (TFA) is a CaMKII substrate that selectively hinders GA response without affecting other plant processes.</p>
    Fórmula:C70H123N20F3O20
    Forma y color:Solid
    Peso molecular:1621.84
  • ZZL-7

    CAS:
    <p>ZZL-7 is a rapid antidepressant targeting nNOS &amp; SERT in DRN, crosses blood-brain barrier, with MDD research potential.</p>
    Fórmula:C11H20N2O4
    Pureza:99.79%
    Forma y color:Soild
    Peso molecular:244.29
  • Lu AF27139

    CAS:
    <p>Lu AF27139: P2X7 receptor antagonist; IC50: 12 nM (human), 2.4 nM (rat); Ki: 22 (mouse), 54 (human), 13 nM (rat); for CNS research.</p>
    Fórmula:C21H19ClF3N5O2S
    Pureza:99.96%
    Forma y color:Solid
    Peso molecular:497.92
  • Tropicamide

    CAS:
    <p>Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.</p>
    Fórmula:C17H20N2O2
    Pureza:99.78% - 99.94%
    Forma y color:White Powder
    Peso molecular:284.35
  • (S)-3,4-DCPG HCl


    <p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>
    Fórmula:C10H10ClNO6
    Pureza:99.53% - 99.9%
    Forma y color:Soild
    Peso molecular:275.64
  • OXA(17-33) TFA


    <p>OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).</p>
    Fórmula:C81H126F3N23O24
    Forma y color:Solid
    Peso molecular:1863
  • SB 258585

    CAS:
    <p>SB 258585: Selective 5-HT6 antagonist, binds human receptors, used in cognitive and antipsychotic assays.</p>
    Fórmula:C18H22IN3O3S
    Pureza:99.8%
    Forma y color:Soild
    Peso molecular:487.36
  • FM04

    CAS:
    <p>FM04 is a potent oral P-gp inhibitor (EC50: 83 nM), disrupting human P-gp NBD2 to enhance cancer treatment.</p>
    Fórmula:C26H25NO4
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:415.48
  • VU6028418

    CAS:
    <p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>
    Forma y color:Solid
  • NT 13 acetate


    <p>NT 13 acetate is a partial agonist of NMDA receptor and can be used for research on depression, anxiety, and other related diseases.</p>
    Fórmula:C20H34N4O9
    Pureza:98%
    Forma y color:Solid
    Peso molecular:474.51
  • ZL-1101


    <p>ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.</p>
    Forma y color:Odour Liquid
  • JF-NP-26


    <p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>
    Forma y color:Solid
  • Anti-Amyloid β Antibody (scFv59)


    <p>Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>
    Forma y color:Odour Liquid
  • OM99-2 TFA

    CAS:
    <p>OM99-2 TFA, an 8-residue inhibitor of brain memapsin 2, has a Ki of 9.58 nM, showing promise in Alzheimer's research.</p>
    Fórmula:C43H65F3N8O16
    Forma y color:Solid
    Peso molecular:1007.028
  • mcK6A1


    <p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>
    Fórmula:C71H99N17O16
    Forma y color:Solid
    Peso molecular:1446.65
  • CPN-267 TFA


    <p>CPN-267 (compound 7b) TFA is a selective agonist of neuromedin U receptor 1 (NMUR1) with an EC50 of 0.25 nM. This compound inhibits weight gain in mice and is applicable in obesity research.</p>
    Fórmula:C54H68F6N16O12S
    Forma y color:Solid
    Peso molecular:1279.27
  • β-Amyloid (1-38), mouse, rat

    CAS:
    <p>β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.</p>
    Forma y color:Solid
  • FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)


    <p>FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.</p>
    Fórmula:C227H330N58O66S2
    Forma y color:Solid
    Peso molecular:4991.53
  • Blestrin D

    CAS:
    <p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>
    Fórmula:C30H24O6
    Forma y color:Solid
    Peso molecular:480.51
  • Nardoguaianone J

    CAS:
    <p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>
    Fórmula:C15H22O2
    Forma y color:Solid
    Peso molecular:234.33
  • Imipramine N-oxide

    CAS:
    <p>Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.</p>
    Fórmula:C19H24N2O
    Pureza:99.80%
    Forma y color:Solid
    Peso molecular:296.41
  • Lisuride maleate

    CAS:
    <p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>
    Fórmula:C24H30N4O5
    Pureza:99.85%
    Forma y color:Solid
    Peso molecular:454.52
  • Fluphenazine-N-2-chloroethane (hydrochloride)

    CAS:
    <p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>
    Fórmula:C22H27Cl3F3N3S
    Forma y color:Solid
    Peso molecular:528.89
  • BTMPS

    CAS:
    <p>BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.</p>
    Fórmula:C28H52N2O4
    Pureza:98.1%
    Forma y color:Solid
    Peso molecular:480.72
  • Adatanserin hydrochloride

    CAS:
    <p>Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.</p>
    Fórmula:C21H32ClN5O
    Pureza:99.64%
    Forma y color:Solid
    Peso molecular:405.96
  • RS 56812

    CAS:
    <p>RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.</p>
    Fórmula:C18H21N3O2
    Pureza:99.38%
    Forma y color:Soild
    Peso molecular:311.38
  • Xenopus orexin B

    CAS:
    <p>Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].</p>
    Fórmula:C130H219N45O40S2
    Forma y color:Solid
    Peso molecular:3116.54
  • AChE/BChE-IN-20


    <p>AChE/BChE-IN-20 (compound 3m) serves as an inhibitor for both acetylcholinesterase (AChE, IC50=34.81 µM) and butyrylcholinesterase (BChE, IC50=20.66 µM). The affinity for the critical enzyme pockets and the favorable interaction profiles were established through molecular docking and kinetics simulation, making it relevant for the study of Alzheimer's disease.</p>
    Forma y color:Odour Solid
  • Antipsychotic agent-2


    <p>Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.</p>
    Fórmula:C22H26FN5O
    Forma y color:Solid
    Peso molecular:395.47
  • AChE-IN-70


    <p>AChE-IN-70 (compound 4) is an acetylcholinesterase inhibitor. It exhibits larvicidal activity against mosquito larvae (Culex pipiens L.), making it useful for mosquito control research.</p>
    Forma y color:Odour Solid
  • Pomaglumetad methionil anhydrous

    CAS:
    <p>LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.</p>
    Fórmula:C12H18N2O7S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:366.41
  • LtIA-F


    <p>LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.</p>
    Fórmula:C86H121N25O22S4
    Forma y color:Solid
    Peso molecular:1985.31
  • GluN2B receptor modulator-1

    CAS:
    <p>GluN2B receptor modulator-1 is a selective negative allosteric modulator of NMDA receptor GluN2B subunits (IC50 31 nM), valuable for neuropharmacology studies.</p>
    Fórmula:C17H15F3N4O2S
    Pureza:99.56%
    Forma y color:Solid
    Peso molecular:396.39
  • Lu AE51090

    CAS:
    <p>Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.</p>
    Fórmula:C24H29N3O3
    Pureza:99.57%
    Forma y color:Solid
    Peso molecular:407.51
  • (±)-Acetylcarnitine chloride

    CAS:
    <p>(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with neuroprotective properties and can be used in studies of neuritis.</p>
    Fórmula:C9H18ClNO4
    Pureza:99.98%
    Forma y color:White Crystalline Powder
    Peso molecular:239.7
  • MK-0969

    CAS:
    <p>MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.</p>
    Fórmula:C24H30F2N4O2
    Forma y color:Solid
    Peso molecular:444.52
  • AChE-IN-49


    <p>AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.</p>
    Fórmula:C31H28BrClN2O3
    Peso molecular:590.09718
  • FITC-β-Ala-Amyloid β-Protein (1-42)

    CAS:
    <p>FITC-β-Ala-Amyloid β-Protein (1-42) is a polypeptide identified through peptide screening. This screening method predominantly utilizes immunoassays to gather active polypeptides and is used in studying protein interactions, conducting functional analyses, and screening antigen epitopes, with particular application in the research and development of active molecules.</p>
    Fórmula:C227H327N57O66S2
    Peso molecular:4971.34251
  • Aβ1-14-εK-KKK-MvF5 Th


    <p>Aβ1-14-εK-KKK-MvF5 Th (UB311 immunogen I) is a biologically active peptide and one of the Aβ1–14 targeting peptides (B-cell epitope) used in UB-311.</p>
    Fórmula:C199H318N56O55
    Peso molecular:4372.38081
  • R 50595

    CAS:
    <p>R 50595 is a selective non-competitive cisapride antagonist.</p>
    Fórmula:C30H35Cl2F2N3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:594.52
  • (S)-Vamicamide

    CAS:
    <p>(S)-Vamicamide is an anti-anticholinergic compound.</p>
    Fórmula:C18H23N3O
    Pureza:99.48% - 99.65%
    Forma y color:Soild
    Peso molecular:297.39
  • Malaoxon

    CAS:
    <p>Malaoxon is used as an insecticide.</p>
    Fórmula:C10H19O7PS
    Forma y color:Solid
    Peso molecular:314.29
  • (Rac)-Sabcomeline

    CAS:
    <p>(Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.</p>
    Fórmula:C10H15N3O
    Pureza:99.14%
    Forma y color:Solid
    Peso molecular:193.25
  • (Rac)-5-Carboxy tolterodine

    CAS:
    <p>(Rac)-5-Carboxy tolterodine is an inactive metabolite of Tolterodine, which acts as a muscarinic acetylcholine receptor antagonist.</p>
    Fórmula:C22H29NO3
    Forma y color:Solid
    Peso molecular:355.47
  • Bis-(-)-8-demethylmaritidine


    <p>Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1</p>
    Forma y color:Odour Solid
  • 5-methoxy-α-Ethyltryptamine

    CAS:
    <p>5-Methoxy-alpha-ethyltryptamine is a psychoactive substance that can cause various effects. It belongs to the tryptamine chemical class and can be used for various psychoactive and stimulant effects. </p>
    Fórmula:C13H18N2O
    Pureza:98.25%
    Forma y color:Solid
    Peso molecular:218.29
  • (+)-Coclaurine hydrochloride

    CAS:
    <p>(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.</p>
    Fórmula:C17H20ClNO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:321.8
  • FGIN-1-43

    CAS:
    <p>FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.</p>
    Fórmula:C28H36Cl2N2O
    Pureza:99.57%
    Forma y color:Solid
    Peso molecular:487.5
  • (Iso)-Atagabalin HCl

    CAS:
    <p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>
    Fórmula:C10H20ClNO2
    Pureza:99.26% - >99.99%
    Forma y color:Soild
    Peso molecular:221.72