Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(940 productos)
- ACK(1 productos)
- AChR(574 productos)
- ATP Citrato Liasa(16 productos)
- Receptor adrenérgico(2.939 productos)
- BACE(36 productos)
- Beta amiloide(204 productos)
- CAMK(68 productos)
- Inhibidores de ciclooxigenasa (COX)(562 productos)
- Receptor de dopamina(407 productos)
- Receptor GABA(336 productos)
- Gamma-secretasa(59 productos)
- GluR(255 productos)
- GlyT(24 productos)
- Receptor de histamina(358 productos)
- LRRK2(33 productos)
- Receptor de melatonina(24 productos)
- NMDAR(28 productos)
- Receptor de OX(40 productos)
- Receptor de opioides(296 productos)
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Se han encontrado 5400 productos de "Neurociencia"
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isomer-Cilansetron
CAS:<p>isomer-Cilansetron is an isomer of Cilansetron.</p>Fórmula:C20H21N3OPureza:99.92% - 99.96%Forma y color:SoildPeso molecular:319.4epi-Aszonalenin A
CAS:<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Fórmula:C25H25N3O3Forma y color:SolidPeso molecular:415.48Rapastinel acetate
CAS:<p>Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.</p>Fórmula:C20H35N5O8Pureza:99.6%Forma y color:SoildPeso molecular:473.52Amyloid β-Protein (3-42)
CAS:<p>Amyloid β-Protein (3-42), the precursor of Pyr peptide, serves as the foundation of the amyloid template block in Alzheimer's disease when modified to</p>Forma y color:SolidPSEN1-IN-1
<p>PSEN1-IN-1 (Compound (+)-13b) functions as an inhibitor of PSEN1, displaying potent inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with respective IC50</p>Fórmula:C20H19ClF3NO3SForma y color:SolidPeso molecular:445.88Substance P(1-4) Acetate
<p>Substance P(1-4) Acetate is a neurokinin receptor (NK-R) antagonist, inhibiting the formation of PV EEC.</p>Fórmula:C24H44N8O7Pureza:99.84%Forma y color:SolidPeso molecular:556.66Xylamidine
CAS:<p>Xylamidine is a biochemical.</p>Fórmula:C19H24N2O2Forma y color:SolidPeso molecular:312.41Orexin B, rat, mouse TFA
<p>Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.</p>Fórmula:C128H216F3N45O36SForma y color:SolidPeso molecular:3050.42β-Amyloid (12-20)
CAS:<p>β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has</p>Fórmula:C57H83N15O11Pureza:98%Forma y color:SolidPeso molecular:1154.36(Gln22)-Amyloid β-Protein (1-42)
CAS:<p>(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].</p>Fórmula:C203H312N56O59SForma y color:SolidPeso molecular:4513.05Antidepressant agent 5
CAS:<p>Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine</p>Fórmula:C20H25NO3Pureza:99.34%Forma y color:SoildPeso molecular:327.42Methyllycaconitine citrate
CAS:<p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>Fórmula:C43H58N2O17Pureza:98.03% - 98.91%Forma y color:SolidPeso molecular:874.92(Rac)-5-Carboxy tolterodine
CAS:<p>(Rac)-5-Carboxy tolterodine is an inactive metabolite of Tolterodine, which acts as a muscarinic acetylcholine receptor antagonist.</p>Fórmula:C22H29NO3Forma y color:SolidPeso molecular:355.47BSBM6
CAS:<p>BSBM6 is an inhibitor of Aβ aggregation and neuronal toxicity that acts by reversing the aggregation and toxicity of amyloid-β peptides.</p>Fórmula:C23H29N3O5Pureza:98%Forma y color:SolidPeso molecular:427.49Ebiratide TFA
<p>Ebiratide (HOE-427) TFA is a derivative of ACTH4-9 that exerts its effect directly on the central nervous system, enhancing memory. Ebiratide TFA also promotes the metabolism of acetylcholine (ACh) in the rat brain.</p>Fórmula:C48H73N11O10S·xC2HF3O2Forma y color:SolidPeso molecular:996.23 (free base)P-gb-IN-1
CAS:<p>P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow.</p>Fórmula:C30H28N2O6Pureza:99.58%Forma y color:SoildPeso molecular:512.55CDD0102 HCl
CAS:<p>CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.</p>Fórmula:C8H13ClN4OPureza:99.7%Forma y color:SoildPeso molecular:216.67β-Amyloid (1-15)
CAS:<p>β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.</p>Fórmula:C78H107N25O27Pureza:99.88%Forma y color:SolidPeso molecular:1826.84Brexpiprazole S-oxide
CAS:<p>Brexpiprazole S-oxide is the main metabolite of Brexpiprazole, a human 5-HT1A and dopamine receptor partial agonist (Ki: 0.12, 0.3 nM).</p>Fórmula:C25H27N3O3SPureza:98%Forma y color:SolidPeso molecular:449.57Nemifitide diTFA
CAS:<p>Nemifitide diTFA is a synthetic pentapeptide with antidepressant properties, resembling MIF, that crosses the blood-brain barrier.</p>Fórmula:C37H45F7N10O10Pureza:99.78% - 99.84%Forma y color:SolidPeso molecular:922.8Hydroxytacrine maleate
CAS:<p>Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase inhibitor used in the study of Alzheimer's type dementia (SDAT).</p>Fórmula:C17H18N2O5Pureza:98.84%Forma y color:SolidPeso molecular:330.34Bis-(-)-8-demethylmaritidine
<p>Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1</p>Forma y color:Odour SolidAZD4694 Precursor
CAS:<p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>Fórmula:C22H25N3O7Forma y color:SolidPeso molecular:443.45RS 56812
CAS:<p>RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.</p>Fórmula:C18H21N3O2Pureza:99.38%Forma y color:SoildPeso molecular:311.38BChE-IN-35
<p>BChE-IN-35 (Azo-9) is an inhibitor of BChE. This compound exhibits dynamic cis/trans conformational changes, with the cis isomer preferentially binding to BChE. Additionally, BChE-IN-35 can be utilized in research on Alzheimer's disease (AD).</p>Fórmula:C35H39N5O2Forma y color:SolidPeso molecular:561.72MAO-B-IN-36
<p>MAO-B-IN-36 (Compound A6) is an effective MAO-B inhibitor with an IC50 of 13 nM.</p>Fórmula:C20H14O3Forma y color:SolidPeso molecular:302.325-HT1AR agonist 2
<p>5-HT1AR Agonist 2 (Compound 4f) is a potent agonist of the 5-HT1A receptor with a Ki value of 10.0 nM. It also binds to SERT, D2, and 5-HT6 receptors with Ki values of 2.8 nM, 23 nM, and 192 nM, respectively. Furthermore, this compound demonstrates stability in microsomes and induces hypothermia in mice.</p>Fórmula:C31H31N5O3Forma y color:SolidPeso molecular:521.61COX-2-IN-35
<p>COX-2-IN-35 (compound 7) is a selective inhibitor of COX-2, demonstrating anti-inflammatory activity, with an inhibitory concentration (IC 50) of 4.37 nM [1].</p>Fórmula:C22H19NO2S2Pureza:98%Forma y color:SolidPeso molecular:393.52C18 L-erythro Ceramide (d18:1/18:0)
CAS:<p>C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.</p>Fórmula:C36H71NO3Forma y color:SolidPeso molecular:565.955-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Fórmula:C25H30N4O2SForma y color:SolidPeso molecular:450.6AL 34662
CAS:<p>AL 34662 is a selective and potent 5-HT2A receptor agonist with IC50s of 0.77 nM and 1.5 nM for rat and human 5-HT2 receptors, respectively.AL 34662 is also a</p>Fórmula:C10H13N3OPureza:99.77%Forma y color:SolidPeso molecular:191.235-HT6R antagonist 6
<p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>Fórmula:C24H26N4O2SForma y color:SolidPeso molecular:434.55GABAA receptor modulator-4
<p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>Fórmula:C15H17BrO4SForma y color:SolidPeso molecular:373.26TC-2216
CAS:<p>TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.</p>Fórmula:C12H17N3Pureza:99.33%Forma y color:SolidPeso molecular:203.283-Chloroamphetamine hydrochloride
CAS:<p>3-Chloroamphetamine hydrochloride is a derivative of amphetamine that acts as a central nervous system stimulant by releasing serotonin and dopamine.</p>Fórmula:C9H13Cl2NForma y color:SolidPeso molecular:206.11Tranylcypromine
CAS:<p>Tranylcypromine (SKF 385), a potent monoamine oxidase (MAO) inhibitor [1], is used in medicinal applications.</p>Fórmula:C9H11NPureza:98%Forma y color:SolidPeso molecular:133.19JPC0323
<p>JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequate</p>Fórmula:C22H43NO4Pureza:98%Forma y color:SolidPeso molecular:385.58Anti-inflammatory agent 53
<p>Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest</p>Fórmula:C24H22N2O4SPureza:98%Forma y color:SolidPeso molecular:434.51AChE/MAO-B-IN-7
<p>AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.</p>Fórmula:C22H21N3O3Forma y color:SolidPeso molecular:375.425-HT2A receptor agonist-6
CAS:<p>5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.</p>Fórmula:C18H19N3O3Forma y color:SolidPeso molecular:325.36GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Fórmula:C18H22O2Forma y color:SolidPeso molecular:270.374-Hydroxy MPT
CAS:<p>4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.</p>Fórmula:C14H20N2OForma y color:SolidPeso molecular:232.32β-Amyloid (35-25)
CAS:<p>β-Amyloid (35-25) is the reverse sequence of β-Amyloid (25-35).</p>Fórmula:C45H81N13O14SPeso molecular:1060.27hAChE-IN-3
<p>hAChE-IN-3 (compound 5c) serves as a potent inhibitor for AChE, BuChE, MAO-B, and BACE-1, with respective IC50 values of 0.44, 0.08, 5.15, and 0.38 μM,</p>Fórmula:C30H24ClN3O5Pureza:98%Forma y color:SolidPeso molecular:541.98TB-11
CAS:<p>TB-11 is an inhibitor of Cathepsin D with IC50 values of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), and 48.8 nM (BACE1). It is primarily utilized in oncological research.</p>Fórmula:C52H78N8O12Forma y color:SolidPeso molecular:1007.22MAO-B-IN-24
<p>MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 μM.</p>Fórmula:C20H18N2OPureza:98%Forma y color:SolidPeso molecular:302.37(-)-2-Phenylpropylamine
CAS:<p>(-)-2-Phenylpropylamine ((S)-2-Phenylpropylamine) (compound 3b) functions as an inhibitor for both MAO-A and MAO-B, with Ki values of 584 μM and 156 μM, respectively.</p>Fórmula:C9H13NForma y color:SolidPeso molecular:135.21Riluzole-13C,15N2
CAS:<p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>Fórmula:CC7H5F3OS15N2Forma y color:SolidPeso molecular:237.18Timegadine hydrochloride
CAS:<p>Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine. It is an orally active inhibitor of COX and lipo-oxygenase, effectively suppressing COX in rabbit platelets and rat brain with IC50 values of 5 nM and 20 μM, respectively, and inhibiting lipo-oxygenase in horse and rabbit platelets with an IC50 of 100 μM. Timegadine hydrochloride also exhibits anti-arthritis activity.</p>Fórmula:C20H24ClN5SForma y color:SolidPeso molecular:401.96Femoxetine
CAS:<p>Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.</p>Fórmula:C20H25NO2Pureza:99.1% - 99.35%Forma y color:SolidPeso molecular:311.42
