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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5400 productos de "Neurociencia"

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  • Mirtazapine N-oxide

    CAS:
    <p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>
    Fórmula:C17H19N3O
    Forma y color:Solid
    Peso molecular:281.359
  • BuChE-IN-13


    <p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>
    Forma y color:Odour Solid
  • Azocarnil


    <p>Azocarnil is a GABAergic agonist-enhancer used in neurological system research.</p>
    Forma y color:Odour Solid
  • FFN246

    CAS:
    <p>FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and</p>
    Fórmula:C15H13FN2O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:256.27
  • Biperiden Hydrochloride

    CAS:
    <p>Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.</p>
    Fórmula:C21H30ClNO
    Pureza:98%
    Forma y color:Solid
    Peso molecular:347.92
  • (Met(O)35)-Amyloid β-Protein (1-42)


    <p>(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of</p>
    Fórmula:C203H311N55O61S
    Forma y color:Solid
    Peso molecular:4530.04
  • SIB 1553A

    CAS:
    <p>SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.</p>
    Fórmula:C13H19NOS
    Pureza:99.79%
    Forma y color:Soild
    Peso molecular:237.36
  • SAHM1

    CAS:
    <p>Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.</p>
    Fórmula:C94H162N36O23S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2196.58
  • Calmodulin-Dependent Protein Kinase II 290-309 acetate


    <p>Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).</p>
    Fórmula:C105H189N31O26S
    Pureza:96.7%
    Forma y color:Solid
    Peso molecular:2333.88
  • RAGE antagonist peptide

    CAS:
    <p>RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.</p>
    Fórmula:C57H101N13O17S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1272.56
  • β-Amyloid (22-40)

    CAS:
    <p>This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.</p>
    Fórmula:C78H135N21O26S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1815.1
  • Bensultap

    CAS:
    <p>Bensultap is an agricultural chemical typically used as a pesticide.</p>
    Fórmula:C17H21NO4S4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:431.61
  • ECPLA

    CAS:
    <p>ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.</p>
    Fórmula:C21H25N3O
    Forma y color:Solid
    Peso molecular:335.44
  • Bleformin A

    CAS:
    <p>Bleformin A, a natural BChE inhibitor from Bletilla striata, has a 5.2 μM IC50 and is studied for Alzheimer's research.</p>
    Fórmula:C23H20O5
    Forma y color:Solid
    Peso molecular:376.4
  • OM99-2

    CAS:
    <p>OM99-2, an 8-residue peptidomimetic, binds memapsin 2 with 9.58 nM Ki; promising for Alzheimer's research.</p>
    Fórmula:C41H64N8O14
    Forma y color:Solid
    Peso molecular:893.005
  • Osmanthuside B

    CAS:
    <p>Osmanthuside B, isolated from Pseuderanthemum carruthersii (Seem.) Guill.</p>
    Fórmula:C29H36O13
    Forma y color:Solid
    Peso molecular:592.59
  • Acetyl-Tau Peptide (273-284) amide

    CAS:
    <p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>
    Fórmula:C64H116N18O17
    Forma y color:Solid
    Peso molecular:1409.72
  • MAO-B-IN-38


    <p>MAO-B-IN-38 (Compound 6b) is a reversible, competitive inhibitor of MAO-B, exhibiting IC50 values of 0.03 µM for MAO-B and 21.46 µM for MAO-A. This compound is applicable in research on neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.</p>
    Fórmula:C14H17FN4O2S3
    Forma y color:Solid
    Peso molecular:388.504
  • HDAC6-IN-49


    <p>HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.</p>
    Forma y color:Odour Solid
  • Biotin-β-Amyloid (1-42), human TFA


    <p>Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the</p>
    Fórmula:C215H326F3N57O64S2
    Forma y color:Solid
    Peso molecular:4854.36
  • (±)-Acetylcarnitine chloride

    CAS:
    <p>(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with neuroprotective properties and can be used in studies of neuritis.</p>
    Fórmula:C9H18ClNO4
    Pureza:99.98%
    Forma y color:White Crystalline Powder
    Peso molecular:239.7
  • Anti-Amyloid β Antibody (scFv59)


    <p>Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>
    Forma y color:Odour Liquid
  • ALEPH hydrochloride

    CAS:
    <p>ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.</p>
    Fórmula:C12H20ClNO2S
    Forma y color:Solid
    Peso molecular:277.81
  • β-Amyloid (1-43)(human) TFA


    <p>β-Amyloid (1-43)(human) TFA exhibits greater aggregation tendencies and heightened toxicity compared to its well-established counterpart, Aβ1-42.</p>
    Fórmula:C209H319F3N56O64S
    Forma y color:Solid
    Peso molecular:4729.21
  • (Gln22)-Amyloid β-Protein (1-42)

    CAS:
    <p>(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].</p>
    Fórmula:C203H312N56O59S
    Forma y color:Solid
    Peso molecular:4513.05
  • Orexin B, rat, mouse TFA


    <p>Orexin B, rat/mouse TFA, activates OX1-R &amp; OX2-R receptors, influencing food intake, energy, and sleep regulation.</p>
    Fórmula:C128H216F3N45O36S
    Forma y color:Solid
    Peso molecular:3050.42
  • Stacofylline

    CAS:
    <p>Stacofylline is a xanthine derivative that is used to treat migraine headaches.</p>
    Fórmula:C20H33N7O3
    Pureza:99.54% - >99.99%
    Forma y color:Solid
    Peso molecular:419.52
  • Velnacrine

    CAS:
    <p>Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.</p>
    Fórmula:C13H14N2O
    Pureza:99.83%
    Forma y color:Solid
    Peso molecular:214.26
  • AZD4694 Precursor

    CAS:
    <p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>
    Fórmula:C22H25N3O7
    Forma y color:Solid
    Peso molecular:443.45
  • Neocarzinostatin

    CAS:
    <p>Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.</p>
    Pureza:98%
    Forma y color:Solid
    Peso molecular:N/A
  • 5-MeO-pyr-T

    CAS:
    <p>5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.</p>
    Fórmula:C15H20N2O
    Forma y color:Solid
    Peso molecular:244.33
  • Sintamil

    CAS:
    <p>Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.</p>
    Fórmula:C18H20ClN3O4
    Forma y color:Solid
    Peso molecular:377.82
  • C18 L-erythro Ceramide (d18:1/18:0)

    CAS:
    <p>C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.</p>
    Fórmula:C36H71NO3
    Forma y color:Solid
    Peso molecular:565.95
  • β-Amyloid (33-40)

    CAS:
    <p>β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.</p>
    Fórmula:C32H58N8O9S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:730.92
  • OXA(17-33) TFA


    <p>OXA(17-33) TFA: Potent OX1 agonist, ~23x more selective for OX1 (EC50=8.29nM) than OX2 (187nM).</p>
    Fórmula:C81H126F3N23O24
    Forma y color:Solid
    Peso molecular:1863
  • DDC 2′,3′-O-disulfate


    <p>DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].</p>
    Fórmula:C17H16O11S2
    Forma y color:Solid
    Peso molecular:460.43
  • Tiflucarbine

    CAS:
    <p>Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of soluble</p>
    Fórmula:C16H17FN2S
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:288.38
  • (Rac)-5-Carboxy tolterodine

    CAS:
    <p>(Rac)-5-Carboxy tolterodine is an inactive metabolite of Tolterodine, which acts as a muscarinic acetylcholine receptor antagonist.</p>
    Fórmula:C22H29NO3
    Forma y color:Solid
    Peso molecular:355.47
  • Alverine hydrochloride

    CAS:
    <p>Alverine hydrochloride is a parasympatholytic.</p>
    Fórmula:C20H28ClN
    Forma y color:Solid
    Peso molecular:317.9
  • Donitriptan hydrochloride

    CAS:
    <p>Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively</p>
    Fórmula:C23H26ClN5O2
    Pureza:99.8% - 99.86%
    Forma y color:Solid
    Peso molecular:439.94
  • bPiDDB

    CAS:
    <p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>
    Fórmula:C24H38Br2N2
    Pureza:98.72%
    Forma y color:Solid
    Peso molecular:514.38
  • MPPG

    CAS:
    <p>MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).</p>
    Fórmula:C9H12NO5P
    Forma y color:Solid
    Peso molecular:245.171
  • JNJ-67569762

    CAS:
    <p>JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).</p>
    Fórmula:C22H22F4N4O5S
    Forma y color:Solid
    Peso molecular:530.49
  • Aβ-IN-7


    <p>Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomers</p>
    Fórmula:C14H10N2S
    Forma y color:Solid
    Peso molecular:238.31
  • Exosome Compound Library


    <p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>
    Forma y color:Odour Solid
  • Rivanicline 2HCl


    <p>Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.</p>
    Fórmula:C10H16Cl2N2
    Pureza:99.4%
    Forma y color:Soild
    Peso molecular:235.15
  • Furosemide

    CAS:
    <p>Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.</p>
    Fórmula:C12H11ClN2O5S
    Pureza:99.32% - 99.89%
    Forma y color:Crystals From Aqueous Ethanol Tasteless (Ntp 1992)
    Peso molecular:330.744
  • LY 344864 racemate

    CAS:
    <p>LY 344864 racemate is a 5-HT1F receptor agonist.</p>
    Fórmula:C21H22FN3O
    Pureza:99.75%
    Forma y color:Soild
    Peso molecular:351.42
  • PF-03382792

    CAS:
    <p>PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.</p>
    Fórmula:C23H32FN3O4
    Pureza:99.64%
    Forma y color:Solid
    Peso molecular:433.52
  • Fasciculic acid C

    CAS:
    <p>Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>
    Fórmula:C38H63NO11
    Pureza:98%
    Forma y color:Solid
    Peso molecular:709.91