Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(1.025 productos)
- ACK(1 productos)
- AChR(647 productos)
- ATP Citrato Liasa(17 productos)
- Receptor adrenérgico(3.024 productos)
- BACE(37 productos)
- Beta amiloide(230 productos)
- CAMK(73 productos)
- Inhibidores de ciclooxigenasa (COX)(602 productos)
- Receptor de dopamina(445 productos)
- Receptor GABA(373 productos)
- Gamma-secretasa(62 productos)
- GluR(265 productos)
- GlyT(26 productos)
- Receptor de histamina(385 productos)
- LRRK2(43 productos)
- Receptor de melatonina(26 productos)
- NMDAR(10 productos)
- Receptor de OX(41 productos)
- Receptor de opioides(327 productos)
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Se han encontrado 5637 productos de "Neurociencia"
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α-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFórmula:C83H125N27O27S5Pureza:98%Forma y color:SolidPeso molecular:2093.37Asenapine citrate
CAS:Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).Fórmula:C23H24ClNO8Forma y color:SolidPeso molecular:477.89Pseudocoptisine acetate
CAS:Pseudocoptisine acetate is a quaternary alkaloid isolated from the tubers of Corydalis turtschaninovii,with anti-inflammatory properties.Fórmula:C21H17NO6Pureza:98%Forma y color:SolidPeso molecular:379.36Fasciculic acid A
CAS:Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Fórmula:C36H60O8Forma y color:SolidPeso molecular:620.868AChE-IN-37
AChE-IN-37 (compound A2) is an acetylcholinesterase inhibitor with an inhibitory concentration (IC50) of 0.23 µM.Fórmula:C21H12ClNO7SForma y color:SolidPeso molecular:457.84Br-PBTC
CAS:Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.Fórmula:C14H15BrN2OSForma y color:SolidPeso molecular:339.25Orexin B, human
CAS:Orexin B, human agonizes Orexin receptors (OX1 Ki=420 nM, OX2 Ki=36 nM), promotes feeding in rats, and is a neuropeptide.Fórmula:C123H212N44O35SPureza:98%Forma y color:SolidPeso molecular:2899.34Orexin A (human, rat, mouse)
CAS:Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.Fórmula:C152H243N47O44S4Pureza:98%Forma y color:SolidPeso molecular:3561.1PD24
PD24 serves as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with inhibitory concentrations (IC50) of 1.72 μM for humanFórmula:C24H22N2O6Forma y color:SolidPeso molecular:434.44Naratriptan D3 Hydrochloride
CAS:Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.Fórmula:C17H26ClN3O2SPureza:98%Forma y color:SolidPeso molecular:374.94LU-32-176B
CAS:LU32-176B is a bioactive chemical.Fórmula:C23H24F2N2O2Forma y color:SolidPeso molecular:398.45Feralolide
CAS:Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) andFórmula:C18H16O7Forma y color:SolidPeso molecular:344.32AChE-IN-36
AChE-IN-36 (compound A4) is an acetylcholinesterase inhibitor with an IC50 of 0.04 μM, influencing ROS levels and modulating the gene expression of NRF2 [1].Fórmula:C25H21ClO5SForma y color:SolidPeso molecular:468.95Tabernanthalog
CAS:TBG is a 5-HT2A agonist reducing alcohol/heroin cravings and promoting neuroplasticity with antidepressant effects in rodents.Fórmula:C14H18N2OPureza:99.82% - 99.89%Forma y color:SoildPeso molecular:230.31Ref: TM-T60221
1mg175,00€2mg264,00€1mL*10mM (DMSO)344,00€5mg404,00€10mg592,00€25mg888,00€50mg1.243,00€100mg1.701,00€500mg3.402,00€3-Aminopropylphosphinic acid
CAS:3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).
Fórmula:C3H10NO2PForma y color:SolidPeso molecular:123.092Cyclodrine
CAS:Cyclodrine (Cyclopent) is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.Fórmula:C19H29NO3Pureza:97.62%Forma y color:SoildPeso molecular:319.44Ref: TM-T10914L
1mg73,00€1mL*10mM (DMSO)148,00€5mg149,00€10mg212,00€25mg319,00€50mg447,00€100mg610,00€200mg822,00€XL01126
XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.Fórmula:C50H64ClFN10O6S2Forma y color:SolidPeso molecular:1019.69α-Conotoxin PIA
CAS:Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nMFórmula:C79H125N27O25S4Pureza:98%Forma y color:SolidPeso molecular:1981.3FRM-024
CAS:FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment ofFórmula:C22H22ClN5O2Forma y color:SolidPeso molecular:423.9p-HTAA
CAS:Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].Fórmula:C24H16O4S5Forma y color:SolidPeso molecular:528.71Sintamil
CAS:Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.Fórmula:C18H20ClN3O4Forma y color:SolidPeso molecular:377.822-Methyl-1-indanone
CAS:2-Methyl-1-indanone is an acetylcholinesterase inhibitor and can be used for biochemical experiments and drug synthesis.Fórmula:C10H10OPureza:96.6%Forma y color:SolidPeso molecular:146.19β-Amyloid (11-22)
CAS:β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’sFórmula:C70H102N18O18Pureza:98%Forma y color:SolidPeso molecular:1483.67BuChE-IN-21
BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.Fórmula:C16H23NO2Forma y color:SolidPeso molecular:261.17288MGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Fórmula:C8H8FNO5Forma y color:SolidPeso molecular:217.15α-Conotoxin imi
CAS:alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.Fórmula:C52H78N20O15S4Pureza:98%Forma y color:SolidPeso molecular:1351.56UCM 549
CAS:UCM 549 is a bioactive chemical.Fórmula:C19H21NO2Forma y color:SolidPeso molecular:295.385H-Pyrido[4,3-b]indole
CAS:5H-Pyrido[4,3-b]indole is a potential AchE/ChE inhibitor with potential antiviral activity for the study of neurodegenerative diseases.Fórmula:C11H8N2Pureza:99.6%Forma y color:SolidPeso molecular:168.2Atagabalin
CAS:Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.Fórmula:C10H19NO2Forma y color:SolidPeso molecular:185.26Eletriptan
CAS:Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.Fórmula:C22H26N2O2SForma y color:SolidPeso molecular:382.52Sulamserod
CAS:Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular relatedFórmula:C19H28ClN3O5SPureza:98.76%Forma y color:SolidPeso molecular:445.96RA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Forma y color:Odour SolidOXA(17-33)
CAS:Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.Fórmula:C79H125N23O22Pureza:98%Forma y color:SolidPeso molecular:1749N-Ethyl-N-(3-pyridylmethyl)amine
CAS:N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.Fórmula:C8H12N2Pureza:99.65%Forma y color:SolidPeso molecular:136.19Rasagiline 13C3 mesylate racemic
CAS:Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.Fórmula:C13H17NO3SPureza:98%Forma y color:SolidPeso molecular:270.32Anticonvulsant agent 8
Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.Fórmula:C15H11N5OForma y color:SolidPeso molecular:277.28α5-GABAA receptor modulator 1
α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.Fórmula:C21H20FN3O4Forma y color:SolidPeso molecular:397.4BuChE-IN-16
BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.Fórmula:C16H22N2O3Forma y color:SolidPeso molecular:290.362'-O-Succinyl-cAMP
CAS:2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2Fórmula:C14H16N5O9PForma y color:SolidPeso molecular:429.282Xanthohumol I
Xanthohumol I is a natural product that can be used as a reference standard.Fórmula:C21H22O6Forma y color:SolidPeso molecular:370.401Notch 1 TFA
Notch 1 TFA encodes a member of the NOTCH family of proteins.Fórmula:C64H98N15F3O25S3Pureza:98%Forma y color:SolidPeso molecular:1614.81AChE/BChE-IN-15
AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (Fórmula:C29H30N6O3Forma y color:SolidPeso molecular:510.59BChE-IN-21
BChE-IN-21, a potent inhibitor of butyrylcholinesterase (BChE), exhibits an inhibition constant (IC50) of 0.14 ± 0.02 μM, indicating promise for research inForma y color:Odour Solid(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS:(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.
Fórmula:C22H32ClNO2Forma y color:SolidPeso molecular:377.95AChE-IN-29
AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electricFórmula:C18H19BrN2O2Forma y color:SolidPeso molecular:375.265-HT1AR/5-HT6R ligand-1
5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.Fórmula:C25H29ClN4O2SForma y color:SolidPeso molecular:485.04CUR-IPA
CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.Fórmula:C43H38N2O8Forma y color:SolidPeso molecular:710.77Anticonvulsant agent 9
Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.Fórmula:C22H24N4O2Forma y color:SolidPeso molecular:376.45MAO-IN-6
MAO-IN-6 (Compound 3f) is a reversible MAO-B inhibitor that can cross the blood-brain barrier, with an IC50 value of 0.09 μM. It also shows inhibitory activity against AChE and BChE, with IC50 values of 4.48 μM and 17.03 μM, respectively. MAO-IN-6 exhibits low cytotoxicity and is applicable in Alzheimer's disease research.Fórmula:C22H14F3NO2Forma y color:SolidPeso molecular:381.35
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