Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(1.025 productos)
- ACK(1 productos)
- AChR(648 productos)
- ATP Citrato Liasa(17 productos)
- Receptor adrenérgico(3.028 productos)
- BACE(37 productos)
- Beta amiloide(231 productos)
- CAMK(73 productos)
- Inhibidores de ciclooxigenasa (COX)(602 productos)
- Receptor de dopamina(445 productos)
- Receptor GABA(372 productos)
- Gamma-secretasa(63 productos)
- GluR(265 productos)
- GlyT(26 productos)
- Receptor de histamina(385 productos)
- LRRK2(42 productos)
- Receptor de melatonina(26 productos)
- NMDAR(10 productos)
- Receptor de OX(42 productos)
- Receptor de opioides(327 productos)
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Se han encontrado 5637 productos de "Neurociencia"
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Orexin A (human, rat, mouse) (TFA)
Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.Fórmula:C154H244N47F3O46S4Pureza:98%Forma y color:SolidPeso molecular:3675.12Lupanine hydrochloride
CAS:Lupanine hydrochloride, a Sparteine derivative, binds to nAChR with a Ki of 500 nM and has ganglioplegic properties.Fórmula:C15H25ClN2OForma y color:SolidPeso molecular:284.83β-Amyloid (10-35), amide
CAS:β-Amyloid (10-35), amide, is a chemical compound consisting of 26 amino acids, specifically residues 10-35 of the Aβ peptide.Fórmula:C133H205N35O36SPureza:98%Forma y color:SolidPeso molecular:2902.33Lesogaberan napadisylate
CAS:Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.Fórmula:C13H17FNO5PSForma y color:SolidPeso molecular:349.31L-AP3
CAS:L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).Fórmula:C3H8NO5PForma y color:White Hygroscopic SolidPeso molecular:169.073(+)-Cinchonaminone
CAS:(+)-Cinchonaminone shows monoamine oxidase (MAO) inhibitory activity.Fórmula:C19H24N2O2Forma y color:SolidPeso molecular:312.413Heliosupine N-oxide
Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.Fórmula:C20H31NO8Forma y color:SolidPeso molecular:413.467BChE-IN-19
BChE-IN-19 (Compound 7b), a para-substituted indone derivative, exhibits potent inhibitory activity against butyryl cholinesterase (BChE) with an IC50 value ofFórmula:C25H31NO5Forma y color:SolidPeso molecular:425.52Fluphenazine-N-2-chloroethane (hydrochloride)
CAS:Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.Fórmula:C22H27Cl3F3N3SForma y color:SolidPeso molecular:528.89I2-IRs ligand-1
I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.Fórmula:C21H23ClFN2O4PForma y color:SolidPeso molecular:452.84PSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Forma y color:Solidrac-Desethyl Oxybutynin (hydrochloride)
CAS:rac-Desethyl oxybutynin, active oxybutynin metabolite, binds to mAChRs; K_i values 3.12-16 nM; lowers rat micturition pressure.Fórmula:C20H28ClNO3Forma y color:SolidPeso molecular:365.89α-Bungarotoxin
CAS:Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).Fórmula:C338H529N97O105S11Pureza:98%Forma y color:SolidPeso molecular:7984.14Xenopus orexin B
CAS:Xenopus orexin B, a neuropeptide identified as an endogenous ligand for an orphan G-protein-coupled receptor, acts as a potent agonist of OX2R [1].Fórmula:C130H219N45O40S2Forma y color:SolidPeso molecular:3116.54Alverine hydrochloride
CAS:Alverine hydrochloride is a parasympatholytic.Fórmula:C20H28ClNForma y color:SolidPeso molecular:317.91-Ethyl-1H-indole
CAS:1-Ethyl-1H-indole exhibits inhibitory activity against AChE (IC₅₀ = 101 µM) and can be used in related research in the field of life sciences.Fórmula:C10H11NPureza:98.80%Forma y color:SolidPeso molecular:145.2BACE1-IN-15
BACE1-IN-15 (Compound 72) is a selective β-secretase 1 (BACE-1) inhibitor with oral bioavailability and blood-brain barrier permeability, exhibiting an IC50 value of 121.65 nM, and an IC50 of 480.92 nM for BACE-2. BACE1-IN-15 is applicable for research in the field of Alzheimer's disease.Forma y color:Odour SolidAChE/BChE-IN-20
AChE/BChE-IN-20 (compound 3m) serves as an inhibitor for both acetylcholinesterase (AChE, IC50=34.81 µM) and butyrylcholinesterase (BChE, IC50=20.66 µM). The affinity for the critical enzyme pockets and the favorable interaction profiles were established through molecular docking and kinetics simulation, making it relevant for the study of Alzheimer's disease.Forma y color:Odour SolidCalmodulin-Dependent Protein Kinase II (281-309)
CAS:Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).Fórmula:C146H254N46O39S3Pureza:98%Forma y color:SolidPeso molecular:3374.06DOAM
CAS:DOAM is an antagonist of the 5-HT2 receptor.Fórmula:C16H27NO2Forma y color:SolidPeso molecular:265.39Amyloid-Forming peptide GNNQQNY
CAS:Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental inFórmula:C33H48N12O14Forma y color:SolidPeso molecular:836.815-HT5AR/5-HT6R ligand-1
5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.Fórmula:C25H30N4O2SForma y color:SolidPeso molecular:450.6U92016A
CAS:U92016A is a highly potent and selective agonist of 5-HT1A receptor.Fórmula:C19H25N3Pureza:98%Forma y color:SolidPeso molecular:295.42β-Amyloid (1-9)
CAS:This is an N-terminal fragment of beta amyloid.Fórmula:C42H60N14O17Pureza:98%Forma y color:SolidPeso molecular:1033.01α-Conotoxin AuIB
CAS:Selective antagonist of α3β4 nicotinic acetylcholine receptors.Fórmula:C65H89N17O21S4Pureza:98%Forma y color:SolidPeso molecular:1572.76Salvianolic acid H
CAS:Salvianolic acid H is a strong inhibitor of acetylcholinesterase (AChE) [1].Fórmula:C27H22O12Forma y color:SolidPeso molecular:538.46C175-0062
CAS:C175-0062, a monoamine oxidase B (MAO-B) inhibitor, is applicable in research focused on neurodegenerative disorders such as Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS) [1].Fórmula:C21H18N2O5Forma y color:SolidPeso molecular:378.38BSB
CAS:BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.Fórmula:C24H17BrO6Pureza:95.53%Forma y color:SolidPeso molecular:481.29Iloperidone metabolite P95
CAS:Iloperidone metabolite P95, a non-brain penetrating compound, binds 5-HT2A, α1-, α2B-, α2C-receptors with Ki of 7.08-83.18 nM.Fórmula:C23H25FN2O5Forma y color:SolidPeso molecular:428.46AChE-IN-70
AChE-IN-70 (compound 4) is an acetylcholinesterase inhibitor. It exhibits larvicidal activity against mosquito larvae (Culex pipiens L.), making it useful for mosquito control research.Forma y color:Odour SolidEncecalinol
CAS:Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].Fórmula:C14H18O3Forma y color:SolidPeso molecular:234.29β-Secretase Inhibitor I
CAS:β-Secretase Inhibitor I is a highly potent inhibitor of the β-secretase enzyme.Fórmula:C18H18F3N5O2SForma y color:SolidPeso molecular:425.43Quetiapine-d4 fumarate
CAS:Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.Fórmula:C25H29N3O6SPureza:98%Forma y color:SolidPeso molecular:503.61Emamectin B1a
CAS:Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.
Fórmula:C49H75NO13Forma y color:SolidPeso molecular:886.133Kynuramine
CAS:Kynuramine is an aromatic ketone containing the aniline structure.
Fórmula:C9H12N2OForma y color:SolidPeso molecular:164.20nAChR modulator-2
CAS:nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .Fórmula:C12H8ClN3O2Forma y color:SolidPeso molecular:261.66Antipsychotic agent-2
Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.Fórmula:C22H26FN5OForma y color:SolidPeso molecular:395.47AChE/BChE-IN-13
AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximalFórmula:C21H18N8O7Forma y color:SolidPeso molecular:494.422-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione
CAS:2-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione exhibits acetylcholinesterase inhibitory activity with an IC50 of 0.08 µM.Fórmula:C22H24N2O2Pureza:99.41%Peso molecular:348.44Octamylamine
CAS:Octamylamine is a bioactive chemical.Fórmula:C13H29NForma y color:SolidPeso molecular:199.3761β-Amyloid (10-20)
CAS:Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-Fórmula:C71H99N17O16Pureza:98%Forma y color:Lyophilized PowderPeso molecular:1446.65Anisatin
Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.Fórmula:C15H20O8Forma y color:SolidPeso molecular:328.317Ethylpropyltryptamine
CAS:Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.Fórmula:C15H22N2Forma y color:SolidPeso molecular:230.355α-Androst-16-en-3α-ol
CAS:5α-Androst-16-en-3α-ol is a steroid pheromone that has been found in boar testes and human male axillary sweat and has diverse biological activities.1,2ItFórmula:C19H30OForma y color:SolidPeso molecular:274.448AChE-IN-42
Compound AChE-IN-42, also known as Compound 28, is an acetylcholinesterase (AChE) inhibitor with an inhibition constant (K i) of 0.44 μM [1].Forma y color:Odour Solid3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt)
CAS:3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt) can be used in related research in the field of life sciences.Fórmula:C10H10ClNaO3Forma y color:SolidPeso molecular:236.63LtIA-F
LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.Fórmula:C86H121N25O22S4Forma y color:SolidPeso molecular:1985.31Navicixizumab
CAS:Navicixizumab, a bispecific VEGF/DLL4 inhibitor, pairs with Paclitaxel in ovarian and other cancer research.Forma y color:LiquidBiphenyl-3′,3,4,4′-tetrol
CAS:Biphenyl-3′,3,4,4′-tetrol (BPT) is a potent inhibitor of Aβ40 aggregation and can be utilized in research related to neurodegenerative diseases such as Alzheimer's.Fórmula:C12H10O4Forma y color:SolidPeso molecular:218.21
