Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(1.025 productos)
- ACK(1 productos)
- AChR(648 productos)
- ATP Citrato Liasa(17 productos)
- Receptor adrenérgico(3.028 productos)
- BACE(37 productos)
- Beta amiloide(231 productos)
- CAMK(73 productos)
- Inhibidores de ciclooxigenasa (COX)(602 productos)
- Receptor de dopamina(445 productos)
- Receptor GABA(372 productos)
- Gamma-secretasa(63 productos)
- GluR(265 productos)
- GlyT(26 productos)
- Receptor de histamina(385 productos)
- LRRK2(42 productos)
- Receptor de melatonina(26 productos)
- NMDAR(10 productos)
- Receptor de OX(42 productos)
- Receptor de opioides(327 productos)
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Se han encontrado 5637 productos de "Neurociencia"
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LY3027788
CAS:LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.Fórmula:C25H31F2NO11SForma y color:SolidPeso molecular:591.58Syk Inhibitor II hydrochloride
CAS:Syk signaling is key in lupus. Syk inhibitors reduce inflammation and sepsis severity in FcgRIIb-/- mice, lowering cytokines and organ damage.Fórmula:C14H16ClF3N6OPureza:99.05%Forma y color:SolidPeso molecular:376.77LY3027788 hydrochloride
CAS:LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.Fórmula:C25H32ClF2NO11SForma y color:SolidPeso molecular:628.03Anabaseine
CAS:Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.Fórmula:C10H12N2Forma y color:SolidPeso molecular:160.22AHN-683
CAS:AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.Fórmula:C42H32FN3O7Pureza:98%Forma y color:SolidPeso molecular:709.72RuBi-GABA
CAS:Ruthenium-bipyridine-triphenylphosphine caged GABAFórmula:C42H39F6N5O2P2RuPureza:98%Forma y color:SolidPeso molecular:922.8LP 12 hydrochloride
CAS:LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).Fórmula:C32H40ClN3OForma y color:SolidPeso molecular:518.14Heliosupine
Heliosupine is a useful organic compound for research related to life sciences and the catalog number is T125038.Fórmula:C20H31NO7Forma y color:SolidPeso molecular:397.468Methyllycaconitine citrate
CAS:Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.Fórmula:C43H58N2O17Pureza:98.03% - 98.91%Forma y color:SolidPeso molecular:874.92Dehydrodiscretamine chloride
CAS:Dehydrodiscretamine chloride, a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibits IC50 values of 17.8 μM and 118.8 μM,Fórmula:C19H18ClNO4Forma y color:SolidPeso molecular:359.8Bencycloquidium Bromide
CAS:Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.Fórmula:C21H32BrNO2Forma y color:SolidPeso molecular:410.39AChE/BuChE-IN-6
AChE/BuChE-IN-6 (Compound 11f) is an inhibitor of AChE and BuChE, with IC50 values of 1.24 and 1.85 μg/mL, respectively. It exhibits strong DPPH radical scavenging activity (IC50 = 3.15 μg/mL). In vivo toxicity studies demonstrate that AChE/BuChE-IN-6 is safe, showing no significant differences in blood and biochemical parameters compared to controls, and no abnormalities in liver and kidney tissues. This compound shows potential for Alzheimer's disease research.Fórmula:C24H20ClN3O3Forma y color:SolidPeso molecular:433.887hAChE/hBuChE-IN-1
hAChE/hBuChE-IN-1 (compound C2) acts as a dual inhibitor of cholinesterases, exhibiting IC50 values of 514 nM for hAChE and 358 nM for hBuChE. It is orally active and capable of enhancing cognitive function and spatial memory.Fórmula:C30H31FN2O3Forma y color:SolidPeso molecular:486.577β-Amyloid (29-40)
CAS:β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical propertiesFórmula:C49H88N12O13SPureza:98%Forma y color:SolidPeso molecular:1085.36α-Conotoxin EI
CAS:Selective antagonist of neuromuscular nicotinic receptors α1β1γδFórmula:C83H125N27O27S5Pureza:98%Forma y color:SolidPeso molecular:2093.37Asenapine citrate
CAS:Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).Fórmula:C23H24ClNO8Forma y color:SolidPeso molecular:477.89Pseudocoptisine acetate
CAS:Pseudocoptisine acetate is a quaternary alkaloid isolated from the tubers of Corydalis turtschaninovii,with anti-inflammatory properties.Fórmula:C21H17NO6Pureza:98%Forma y color:SolidPeso molecular:379.36Fasciculic acid A
CAS:Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Fórmula:C36H60O8Forma y color:SolidPeso molecular:620.868AChE-IN-37
AChE-IN-37 (compound A2) is an acetylcholinesterase inhibitor with an inhibitory concentration (IC50) of 0.23 µM.Fórmula:C21H12ClNO7SForma y color:SolidPeso molecular:457.84Br-PBTC
CAS:Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.Fórmula:C14H15BrN2OSForma y color:SolidPeso molecular:339.25Orexin B, human
CAS:Orexin B, human agonizes Orexin receptors (OX1 Ki=420 nM, OX2 Ki=36 nM), promotes feeding in rats, and is a neuropeptide.Fórmula:C123H212N44O35SPureza:98%Forma y color:SolidPeso molecular:2899.34Orexin A (human, rat, mouse)
CAS:Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.Fórmula:C152H243N47O44S4Pureza:98%Forma y color:SolidPeso molecular:3561.1PD24
PD24 serves as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with inhibitory concentrations (IC50) of 1.72 μM for humanFórmula:C24H22N2O6Forma y color:SolidPeso molecular:434.44Naratriptan D3 Hydrochloride
CAS:Naratriptan D3 Hydrochloride is the deuterium labeled Naratriptan, is a selective agonist of 5-HT1 receptor subtype.Fórmula:C17H26ClN3O2SPureza:98%Forma y color:SolidPeso molecular:374.94LU-32-176B
CAS:LU32-176B is a bioactive chemical.Fórmula:C23H24F2N2O2Forma y color:SolidPeso molecular:398.45Feralolide
CAS:Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) andFórmula:C18H16O7Forma y color:SolidPeso molecular:344.32AChE-IN-36
AChE-IN-36 (compound A4) is an acetylcholinesterase inhibitor with an IC50 of 0.04 μM, influencing ROS levels and modulating the gene expression of NRF2 [1].Fórmula:C25H21ClO5SForma y color:SolidPeso molecular:468.95Tabernanthalog
CAS:TBG is a 5-HT2A agonist reducing alcohol/heroin cravings and promoting neuroplasticity with antidepressant effects in rodents.Fórmula:C14H18N2OPureza:99.82% - 99.89%Forma y color:SoildPeso molecular:230.31Ref: TM-T60221
1mg175,00€2mg264,00€1mL*10mM (DMSO)344,00€5mg404,00€10mg592,00€25mg888,00€50mg1.243,00€100mg1.701,00€500mg3.402,00€3-Aminopropylphosphinic acid
CAS:3-Aminopropylphosphinic acid (3-APPA) is a phosphonic analog of gamma-aminobutyric acid (GABA).
Fórmula:C3H10NO2PForma y color:SolidPeso molecular:123.092Cyclodrine
CAS:Cyclodrine (Cyclopent) is a cholinergic (muscarinic, nicotinic) (mAChR and nAChR) receptor antagonist.Fórmula:C19H29NO3Pureza:97.62%Forma y color:SoildPeso molecular:319.44Ref: TM-T10914L
1mg73,00€1mL*10mM (DMSO)148,00€5mg149,00€10mg212,00€25mg319,00€50mg447,00€100mg610,00€200mg822,00€BMS-906024
CAS:BMS-906024 (Osugacestat) is a gamma secretase inhibitor, a Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity.Fórmula:C26H26F6N4O3Pureza:99.88% - >99.99%Forma y color:SolidPeso molecular:556.5XL01126
XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.Fórmula:C50H64ClFN10O6S2Forma y color:SolidPeso molecular:1019.69α-Conotoxin PIA
CAS:Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nMFórmula:C79H125N27O25S4Pureza:98%Forma y color:SolidPeso molecular:1981.3AC3-I, myristoylated
Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).
Fórmula:C78H137N21O20Pureza:98%Forma y color:SolidPeso molecular:1689.05FRM-024
CAS:FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment ofFórmula:C22H22ClN5O2Forma y color:SolidPeso molecular:423.9MmTx1 toxin
Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].Fórmula:C295H455N95O97S10Pureza:98%Forma y color:SolidPeso molecular:7205CaMKIIα-PHOTAC
CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).Fórmula:C54H58Cl2N10O11Pureza:98%Forma y color:SolidPeso molecular:1094GAD65(247-266) epitope TFA
GAD65(247-266) epitope TFA, a T cell epitope derived from islet antigens, exhibits competitive binding to the type I diabetes-associated molecule I-A g7, albeitFórmula:C111H174F3N27O29S4Pureza:98%Forma y color:SolidPeso molecular:2535.99Calmodulin Kinase IINtide, Myristoylated
Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].Fórmula:C156H275N47O43Pureza:98%Forma y color:SolidPeso molecular:3497.14p-HTAA
CAS:Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].Fórmula:C24H16O4S5Forma y color:SolidPeso molecular:528.71Sintamil
CAS:Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.Fórmula:C18H20ClN3O4Forma y color:SolidPeso molecular:377.82PZ-1922
PZ-1922 (Compound 16), able to cross the blood-brain barrier, is a dual antagonist for 5-HT6R and 5-HT3R with K i values of 17 nM and 0.45 nM, respectively.Pureza:98%Forma y color:Odour Solid2-Methyl-1-indanone
CAS:2-Methyl-1-indanone is an acetylcholinesterase inhibitor and can be used for biochemical experiments and drug synthesis.Fórmula:C10H10OPureza:96.6%Forma y color:SolidPeso molecular:146.19β-Amyloid (11-22)
CAS:β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’sFórmula:C70H102N18O18Pureza:98%Forma y color:SolidPeso molecular:1483.67IHC3
IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.Fórmula:C17H12FN3OPureza:98%Forma y color:SolidPeso molecular:293.3MAOA-IN-1
MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.Fórmula:C13H16Cl2N2O2Pureza:98%Forma y color:SolidPeso molecular:303.18BuChE-IN-21
BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.Fórmula:C16H23NO2Forma y color:SolidPeso molecular:261.17288GABA receptor Antagonist 1
GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.Pureza:98%Forma y color:Odour SolidMGS0028
CAS:MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.Fórmula:C8H8FNO5Forma y color:SolidPeso molecular:217.15
