Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(1.025 productos)
- ACK(1 productos)
- AChR(647 productos)
- ATP Citrato Liasa(17 productos)
- Receptor adrenérgico(3.025 productos)
- BACE(37 productos)
- Beta amiloide(230 productos)
- CAMK(73 productos)
- Inhibidores de ciclooxigenasa (COX)(602 productos)
- Receptor de dopamina(445 productos)
- Receptor GABA(373 productos)
- Gamma-secretasa(62 productos)
- GluR(265 productos)
- GlyT(26 productos)
- Receptor de histamina(385 productos)
- LRRK2(43 productos)
- Receptor de melatonina(26 productos)
- NMDAR(10 productos)
- Receptor de OX(41 productos)
- Receptor de opioides(327 productos)
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Se han encontrado 5639 productos de "Neurociencia"
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EB-42486
CAS:EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.Fórmula:C22H22N8OPureza:99.53%Forma y color:SolidPeso molecular:414.46Ref: TM-T39972
1mg66,00€2mg87,00€5mg147,00€1mL*10mM (DMSO)161,00€10mg215,00€25mg388,00€50mg577,00€100mg820,00€200mg1.099,00€Choline Chloride-13C3
Choline Chloride-13C3 is a 13C-labeled variant of choline (chloride). This organic compound and quaternary ammonium salt serves as a substrate for acyl receptors and choline acetyltransferase. Additionally, it acts as a photosynthesis enhancer in plants and is employed as a feed additive for poultry and livestock, promoting egg and offspring production.Forma y color:Odour SolidDISC-0974
DISC-0974 is a humanized antibody targeting RGMC/HFE2, which can be used to study urogenital system diseases.Forma y color:LiquidPeso molecular:145.66 kDaDalidnetug
CAS:Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.Forma y color:LiquidMethylatropine (nitrate)
CAS:Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.Fórmula:C18H26N2O6Forma y color:SolidPeso molecular:366.414BChE-IN-12
CAS:BChE-IN-12, non-competitive BChE inhibitor from Bletilla striata, IC50=2.3μM; potential Alzheimer’s research.Fórmula:C31H30O5Forma y color:SolidPeso molecular:482.57BChE-IN-16
BChE-IN-16 (compound 87) is a potent inhibitor of human butyrylcholinesterase (hBChE) exhibiting an inhibition concentration half-maximum (IC50) of 3.8 nM.Fórmula:C28H32FNO2Forma y color:SolidPeso molecular:433.56β-Amyloid (1-11)
CAS:Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFórmula:C56H76N16O22Pureza:98%Forma y color:SolidPeso molecular:1325.3VVZ-149
VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.Forma y color:SolidTIM-098a
TIM-098a is a selective AAK1 inhibitor with an IC50 of 0.24 µM. It does not inhibit CaMKK isoforms. By inhibiting AAK1 kinase activity, TIM-098a disrupts AAK1-regulated endocytosis.
Fórmula:C18H11N3O2Peso molecular:301.085134-Methylamphetamine hydrochloride
CAS:4-Methylamphetamine hydrochloride is a 5-HT1A receptor agonist that induces a decrease in body temperature in rats by binding to the 5-HT1A receptor. Additionally, it increases the extracellular levels of neurotransmitters norepinephrine (NE), dopamine (DA), and serotonin (5-HT) by affecting their transporters. 4-Methylamphetamine hydrochloride is applicable in the study of neurological disorders.Fórmula:C10H16ClNForma y color:SolidPeso molecular:185.69Xylamidine
CAS:Xylamidine is a biochemical.Fórmula:C19H24N2O2Forma y color:SolidPeso molecular:312.41KGP-25
KGP-25 is an inhibitor of the voltage-gated sodium channel 1.8 (Nav1.8), utilized for analgesia by targeting the peripheral nervous system (PNS). Additionally, it targets the γ-aminobutyric acid subtype A receptor (GABAA) in the central nervous system (CNS) for use as a general anesthetic.Forma y color:Odour SolidZZL-7
CAS:ZZL-7 is a rapid antidepressant targeting nNOS & SERT in DRN, crosses blood-brain barrier, with MDD research potential.Fórmula:C11H20N2O4Pureza:99.64%Forma y color:SoildPeso molecular:244.29SKF-83566 hydrochloride
CAS:SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.Fórmula:C17H19BrClNOPureza:99.27%Forma y color:SoildPeso molecular:368.69Desfesoterodine
CAS:Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.Fórmula:C22H31NO2Pureza:99.77%Forma y color:SolidPeso molecular:341.49Ref: TM-T6364
1mg63,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg205,00€25mg353,00€50mg520,00€100mg750,00€500mg1.521,00€nAChR agonist 2
CAS:Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,Fórmula:C11H16N2Forma y color:SolidPeso molecular:176.263γ-Acetylenic GABA hydrochloride
CAS:γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.Fórmula:C6H10ClNO2Pureza:97.83% - 99.44%Forma y color:SolidPeso molecular:163.6Amyloid β Peptide (42-1)(human) acetate
Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42).Pureza:95.20%Forma y color:SoildRiluzole-13C,15N2
CAS:Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.Fórmula:CC7H5F3OS15N2Forma y color:SolidPeso molecular:237.18Ethylpropyltryptamine
CAS:Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.Fórmula:C15H22N2Forma y color:SolidPeso molecular:230.35AChE-IN-49
AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.Fórmula:C31H28BrClN2O3Peso molecular:590.09718K1833
K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$.Forma y color:Odour SolidmHTT-IN-1
CAS:mHTT-IN-1 is a potent inhibitor of toxic mHTT, linked to Huntington's disease, with an EC50 of 46 nM.Fórmula:C18H19N7OSForma y color:SolidPeso molecular:381.45AMI-193
CAS:AMI-193 (Spiramide) is a selective 5-HT2 & D2 receptor antagonist with antipsychotic properties.Fórmula:C22H26FN3O2Pureza:99.65%Forma y color:SolidPeso molecular:383.46Methoxy-X04
CAS:Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).
Fórmula:C23H20O3Pureza:98.96%Forma y color:SolidPeso molecular:344.4Vanutide cridificar
CAS:Vanutide cridificar (ACC-001) is an aminoterminal Aβ1-7 peptide conjugate, employed in Alzheimer’s disease (AD) research [1].Forma y color:LiquidOrexin A (human, rat, mouse) acetate
Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.Fórmula:C154H247N47O46S4Forma y color:SolidPeso molecular:3621.15[Ala11,D-Leu15]-Orexin B acetate
[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).Fórmula:C122H210N44O37SPureza:98.18%Forma y color:SolidPeso molecular:2917.31Coumarinic acid
CAS:Coumarinic acid serves as a brain-penetrating inhibitor of AChE (acetylcholinesterase) and β-amyloid, with applications in anti-Alzheimer's drug research [1].Fórmula:C9H8O3Forma y color:SolidPeso molecular:164.16Aceclidine (hydrochloride)
CAS:agonist of muscarinic receptorsFórmula:C9H16ClNO2Pureza:98%Forma y color:SolidPeso molecular:205.68Rovalpituzumab MMAE
Rovalpituzumab-MMAE (Anti-DLL3 Reference Antibody), produced in CHO cells, consists of a huIgG1 heavy chain and a hukappa light chain. The molecular weight of this antibody is predicted to be 145.02 kDa.Forma y color:LiquidPeso molecular:145 kDa2,3-Dehydrosilybin A
CAS:2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.Fórmula:C25H20O10Forma y color:SolidPeso molecular:480.43SIB 1553A
CAS:SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.Fórmula:C13H19NOSPureza:99.79%Forma y color:SoildPeso molecular:237.36Millmerranone A
Millmerranone A shows the acetylcholinesterase inhibitory property.Fórmula:C27H28O9Forma y color:SolidPeso molecular:496.51Paecilomide
CAS:Paecilomide is a pyridone alkaloid and acetylcholinesterase inhibitor [1] .Fórmula:C12H15NO4Forma y color:SolidPeso molecular:237.25Small Cardioactive Peptide B (SCPB)
CAS:SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).Fórmula:C52H80N14O11S2Pureza:98%Forma y color:SolidPeso molecular:1141.41ACG548B
CAS:ACG548B inhibits AChE/BChE with IC50s of 1.78/0.496 μM; favors AChE over BChE/ChoK.Fórmula:C38H34Br2Cl2N4Forma y color:SolidPeso molecular:777.43TAT-CN21
TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.Fórmula:C169H303N69O43Forma y color:SolidPeso molecular:3989.65Aloveroside A
CAS:Aloveroside A, a triglucosylnaphthalene derivative extracted from Aloe vera using ethanol, exhibits modest inhibitory activity against bACE, demonstratingFórmula:C30H40O17Forma y color:SolidPeso molecular:672.63Fabesetron
CAS:Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.
Fórmula:C18H19N3OForma y color:SolidPeso molecular:293.37AChE-IN-60
AChE-IN-60 (compound 6k) is a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 27 nM and 43 nM, respectively. It also inhibits monoamine oxidase MAO-A and MAO-B, with IC50 values of 353 nM and 716 nM, respectively.Fórmula:C24H29N3O4S3Peso molecular:519.13202M1/M4 muscarinic agonist 2
Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].Forma y color:Odour Solid5α-Androst-16-en-3α-ol
CAS:5α-Androst-16-en-3α-ol is a steroid pheromone that has been found in boar testes and human male axillary sweat and has diverse biological activities.1,2ItFórmula:C19H30OForma y color:SolidPeso molecular:274.448Trontinemab
CAS:Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).Pureza:96.77% - 99%Forma y color:LiquidPeso molecular:194.25 kDaSerazapine
CAS:Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.
Fórmula:C22H23N3O2Pureza:98.71% - 99.57%Forma y color:SolidPeso molecular:361.44Isograndifoliol
CAS:Isograndifoliol: BChE inhibitor (IC50=0.9μM), weaker AChE inhibitor (IC50=342.9μM), with vasorelaxant and anti-tumor properties.Fórmula:C19H26O3Forma y color:SolidPeso molecular:302.41Lanuginosine
CAS:Lanuginosine, an aporphine alkaloid, exhibits cytotoxicity against U251.Fórmula:C18H11NO4Forma y color:SolidPeso molecular:305.28Biperiden Hydrochloride
CAS:Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.Fórmula:C21H30ClNOPureza:98%Forma y color:SolidPeso molecular:347.92
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