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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5389 productos de "Neurociencia"

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  • WAY208466 dihydrochloride

    CAS:
    <p>WAY208466 dihydrochloride is a 5-HT6 receptor agonist (EC50=7.3 nM) with antidepressant and anxiolytic activity.</p>
    Fórmula:C17H20Cl2FN3O2S
    Pureza:98.43%
    Forma y color:Solid
    Peso molecular:420.33
  • VU0463841

    CAS:
    <p>VU0463841 is a mGlu5 negative allosteric modulators.</p>
    Fórmula:C13H8ClFN4O
    Forma y color:Solid
    Peso molecular:290.68
  • Lesogaberan

    CAS:
    <p>Lesogaberan: selective GABAB agonist, EC50 8.6 nM, Ki 5.1 nM in rats, weak GABAA affinity (Ki 1.4 μM).</p>
    Fórmula:C3H9FNO2P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:141.08
  • VU 0360172 hydrochloride

    CAS:
    <p>positive allosteric modulator of mGlu5 receptors</p>
    Fórmula:C18H16ClFN2O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:330.78
  • BChE-IN-6

    CAS:
    <p>BChE-IN-6 inhibits BChE with a Ki of 0.182 μM and chelates Zn 2+, useful in AD research.</p>
    Fórmula:C24H29N3O2
    Forma y color:Solid
    Peso molecular:391.51
  • Alvameline

    CAS:
    Alvameline (Lu25-109) is a partial M1 agonist. Alvameline (Lu25-109) also is a M2/M3 antagonist.
    Fórmula:C9H15N5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:193.25
  • 2-Iodomelatonin

    CAS:
    <p>2-Iodomelatonin, Ki 28 pM, is an MT1 agonist, &gt;5x selective over MT2, used to map melatonin sites in brain/tissues.</p>
    Fórmula:C13H15IN2O2
    Pureza:99.7%
    Forma y color:Solid
    Peso molecular:358.17
  • Tracazolate hydrochloride

    CAS:
    <p>Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.</p>
    Fórmula:C16H25ClN4O2
    Pureza:99.52%
    Forma y color:Solid
    Peso molecular:340.85
  • CBP501

    CAS:
    <p>CBP501 peptide inhibits kinases like MAPKAP-K2/C-Tak1/CHK1, preventing Cdc25C function and blocking the entry into mitosis.</p>
    Fórmula:C86H122F5N29O17
    Forma y color:Solid
    Peso molecular:1929.06
  • DREADD agonist 21 dihydrochloride

    CAS:
    <p>DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].</p>
    Fórmula:C17H20Cl2N4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:351.27
  • CIA-1 hcl(452087-38-6 Free base)

    CAS:
    <p>CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of</p>
    Fórmula:C17H20ClN3O2S
    Pureza:99.02%
    Forma y color:Solid
    Peso molecular:365.88
  • Lilly 51641

    CAS:
    <p>Lilly 51641 is used as a MAO inhibitor.</p>
    Fórmula:C11H14ClNO
    Pureza:98%
    Forma y color:Solid
    Peso molecular:211.69
  • GR 113808

    CAS:
    <p>GR 113808 is a 5-HT4 receptor antagonist that inhibits 5-HT1B and 5-HT3 receptors and attenuates morphine-stimulated dopamine release in the rat striatum.</p>
    Fórmula:C19H27N3O4S
    Pureza:98.16%
    Forma y color:Solid
    Peso molecular:393.5
  • Foliglurax

    CAS:
    Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).
    Fórmula:C23H23N3O3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:421.51
  • TIK-301

    CAS:
    <p>TIK-301 is a chlorinated melatonin derivative and a potent, high-affinity, and orally active melatonin MT1 and MT2 receptors agonist (Kis: 0.081 nM and 0.042 nM</p>
    Fórmula:C14H17ClN2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:280.75
  • DL-AP4 Sodium salt

    CAS:
    Broad spectrum EAA ligand
    Fórmula:C4H10NNaO5P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:206.09
  • Trimipramine

    CAS:
    <p>Trimipramine is an antidepressant with an anxiety-reducing sedative component to its action.</p>
    Fórmula:C20H26N2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:294.43
  • 2-Hydroxysaclofen

    CAS:
    2-Hydroxysaclofen is a GABAB receptor antagonist.
    Fórmula:C9H12ClNO4S
    Pureza:98%
    Forma y color:White Solid
    Peso molecular:265.71
  • VU6001376

    CAS:
    <p>VU6001376 is an effective and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (EC50: 50.1 nM).</p>
    Fórmula:C18H14F2N6OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:400.41
  • VU0090157

    CAS:
    <p>VU0090157, a novel allosteric potentiators of M1 muscarinic receptor, may provide novel treatments for schizophrenia and Alzheimer's disease.</p>
    Fórmula:C19H21N3O7
    Pureza:98%
    Forma y color:Solid
    Peso molecular:403.39
  • (S)-VQW-765


    <p>(S)-VQW-765, oral α7 nAChR partial agonist, may improve cognition in Alzheimer's and schizophrenia.</p>
    Fórmula:C19H22N2O
    Forma y color:Solid
    Peso molecular:294.39
  • PRX933 hydrochloride

    CAS:
    <p>PRX933 hydrochloride (GW876167 hydrochloride) is an agonist of 5-HT2C receptor and can be used in studies about hypertension acute treatment.</p>
    Fórmula:C16H22ClN5O2
    Pureza:99.51% - 99.89%
    Forma y color:Solid
    Peso molecular:351.84
  • 8-M-PDOT

    CAS:
    <p>8-M-PDOT (AH-002) is an MT2 receptor agonist that inhibits MT1.8-M-PDOT has anxiolytic activity and may be used in the study of neuropathic pain.</p>
    Fórmula:C14H19NO2
    Pureza:99.54% - 99.54%
    Forma y color:Solid
    Peso molecular:233.31
  • Thiochrome

    CAS:
    <p>Thiochrome is a selective enhancer of M4 muscarinic receptor of acetylcholine (ACh) affinity.</p>
    Fórmula:C12H14N4OS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:262.33
  • S-22153

    CAS:
    <p>S22153 is an antagonist of melatonin receptor.</p>
    Fórmula:C14H17NOS
    Forma y color:Solid
    Peso molecular:247.36
  • 2-PAT

    CAS:
    <p>2-PAT: reversible MAO-A inhib., IC50=0.721 µM; MAO-B inactivator, IC50=14.6 µM; potential in Parkinson's/depression study.</p>
    Fórmula:C13H15N
    Forma y color:Solid
    Peso molecular:185.26
  • GR 128107

    CAS:
    <p>GR 128107 is an antagonist of melatonin receptor.</p>
    Fórmula:C16H20N2O2
    Forma y color:Solid
    Peso molecular:272.34
  • Cimetropium Bromide

    CAS:
    <p>Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.</p>
    Fórmula:C21H28BrNO4
    Forma y color:Solid
    Peso molecular:438.36
  • SGC-AAK1-1N

    CAS:
    <p>SGC-AAK1-1N is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) with an IC 50 of 1.8 μM [1].</p>
    Fórmula:C20H22N4O3S
    Forma y color:Solid
    Peso molecular:398.48
  • Chrysamine G

    CAS:
    <p>Chrysamine G, Congo red analog, blocks Aβ toxicity, probes Alzheimer's amyloid.</p>
    Fórmula:C26H16N4Na2O6
    Forma y color:Solid
    Peso molecular:526.416
  • CGS 20625

    CAS:
    <p>partial agonist for the benzodiazepine binding site of the GABAA receptor</p>
    Fórmula:C18H19N3O2
    Pureza:99.61%
    Forma y color:Solid
    Peso molecular:309.36
  • Pralidoxime

    CAS:
    <p>Pralidoxime reactivates AChE blocked by nerve agents, aiding as an organophosphate poisoning antidote.</p>
    Fórmula:C7H9N2O
    Forma y color:Solid
    Peso molecular:137.16
  • SX-3228

    CAS:
    SX-3228 is a selective agonist of benzodiazepine1 (BZ1) receptor(IC50 of 17 nM).
    Fórmula:C18H18N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:338.36
  • SC58451

    CAS:
    <p>SC58451 is a novel potent, orally active and selective COX-2 inhibitor.SC58451 showed anti-inflammatory activity in a rat model of arthritis.</p>
    Fórmula:C20H19FO2S
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:342.43
  • Beperidium iodide

    CAS:
    <p>Beperidium iodide is a competitive antagonist of the acetylcholine receptor (pA2: 7.93).</p>
    Fórmula:C23H34IN3O3
    Forma y color:Solid
    Peso molecular:527.44
  • Penbutolol

    CAS:
    <p>Penbutolol is a nonselective beta-blocker utilized as an antihypertensive and an antianginal.</p>
    Fórmula:C18H29NO2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:291.43
  • Eucatropine

    CAS:
    <p>Eucatropine, an anticholinergic agent, acts as a potent inhibitor of the muscarinic acetylcholine receptor (mAChR) with an IC 50 value of 0.583 μM.</p>
    Fórmula:C17H25NO3
    Forma y color:Solid
    Peso molecular:291.39
  • AZ-4217

    CAS:
    <p>AZ-4217: potent BACE inhibitor, reduces amyloid in mice, IC50 160 pM in SH-SY5Y cells, effective in vivo.</p>
    Fórmula:C30H25FN4O
    Forma y color:Solid
    Peso molecular:476.54
  • AChE/BuChE-IN-1

    CAS:
    <p>AChE/BuChE-IN-1: BuChE inhibitor (IC50=0.48µM), weaker AChE blocker (IC50=7.16µM), ·OH scavenger (IC50=0.1674µM), may aid in AD research.</p>
    Fórmula:C19H19NO4
    Forma y color:Solid
    Peso molecular:325.36
  • PF-04781340

    CAS:
    PF-04781340 is an effective, selective, and CNS penetrant agonist of 5-HT2C receptor.
    Fórmula:C17H21N3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:267.37
  • BMS-902483

    CAS:
    <p>BMS-902483: potent α7 partial agonist; enhances rodent cognition; α7 EC50=9.3nM; 5-HT3A IC50=480nM.</p>
    Fórmula:C18H20N4O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:308.38
  • RLH 033

    CAS:
    <p>RLH 033 is a selective ligand for the sigma 1 recognition site.</p>
    Fórmula:C25H31ClN2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:458.98
  • Bradanicline HCl

    CAS:
    <p>Bradanicline(TC-5619) is the agonist of Alpha-7 Nicotinic Receptor.</p>
    Fórmula:C22H24ClN3O2
    Forma y color:Solid
    Peso molecular:397.9
  • AChE/MAO-B-IN-3


    <p>AChE/MAO-B-IN-3: dual inhibitor for AChE (IC50 = 0.0257 µM) and MAO-B (IC50 = 0.0456 µM), researched for Alzheimer's.</p>
    Fórmula:C24H28N2O4
    Forma y color:Solid
    Peso molecular:408.49
  • AT-1001

    CAS:
    <p>AT-1001 is an α3β4 nAChR partial agonist reducing nicotine relapse and withdrawal with negligible impact on food response and dopamine release.</p>
    Fórmula:C15H21BrN2
    Forma y color:Solid
    Peso molecular:309.24
  • Cyclopenin

    CAS:
    <p>Cyclopenin is an inhibitor of acetylcholinesterase (AChE; IC50 = 2.04 μM for human recombinant AChE).</p>
    Fórmula:C17H14N2O3
    Forma y color:Solid
    Peso molecular:294.3
  • 5-HT2A receptor agonist-2

    CAS:
    <p>Potent 5-HT2A receptor agonist-2 targets 5-HT2A/B/C with EC50 1.7, 0.58, 0.50 nM.</p>
    Fórmula:C20H21ClN2O3
    Forma y color:Solid
    Peso molecular:372.85
  • COX-2-IN-2

    CAS:
    <p>COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.</p>
    Fórmula:C17H12FN3O2S
    Pureza:97.62%
    Forma y color:Solid
    Peso molecular:341.36
  • Territrem B

    CAS:
    <p>Territrem B: A mycotoxin that irreversibly blocks AChE, causes tremors in mice at 0.21 mg/kg.</p>
    Fórmula:C29H34O9
    Forma y color:Solid
    Peso molecular:526.57
  • AChE-IN-20

    CAS:
    <p>AChE-IN-20: AChE inhibitor (IC50: 397.32 nM), hCA-I/II blocker (IC50: ~77 nM avg), α GLY suppressor (IC50: 52.08 nM).</p>
    Fórmula:C22H20N8O6S2
    Forma y color:Solid
    Peso molecular:556.57