Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(939 productos)
- ACK(1 productos)
- AChR(575 productos)
- ATP Citrato Liasa(16 productos)
- Receptor adrenérgico(2.945 productos)
- BACE(36 productos)
- Beta amiloide(205 productos)
- CAMK(69 productos)
- Inhibidores de ciclooxigenasa (COX)(561 productos)
- Receptor de dopamina(407 productos)
- Receptor GABA(336 productos)
- Gamma-secretasa(59 productos)
- GluR(255 productos)
- GlyT(24 productos)
- Receptor de histamina(358 productos)
- LRRK2(33 productos)
- Receptor de melatonina(24 productos)
- NMDAR(28 productos)
- Receptor de OX(40 productos)
- Receptor de opioides(297 productos)
Mostrar 12 subcategorías más
Se han encontrado 5398 productos de "Neurociencia"
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LY450108
CAS:<p>LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.</p>Fórmula:C19H22F2N2O3SPureza:98.87% - 99.91%Forma y color:SolidPeso molecular:396.45PGP-4008
CAS:<p>PGP-4008 is a selective and potent P-glycoprotein (Pgp) inhibitor that inhibits tumor growth by co-administration with Doxorubicin.</p>Fórmula:C26H23N3OPureza:98.07% - 98.95%Forma y color:SolidPeso molecular:393.48JY-XHe-053
CAS:<p>JY-XHe-053 is a selective modulator of GABAA receptors.</p>Fórmula:C22H16FN3O2Pureza:98%Forma y color:SolidPeso molecular:373.38RS-0466
CAS:<p>RS-0466 is an β-amyloid-induced cytotoxicity inhibitor.</p>Fórmula:C17H17N5O2Pureza:98%Forma y color:SolidPeso molecular:323.35Suclofenide
CAS:<p>Suclofenide: a benzenesulfonamide anticonvulsant, effective in mouse seizure models, with side effects like lethargy and diarrhea.</p>Fórmula:C16H13ClN2O4SPureza:98%Forma y color:SolidPeso molecular:364.8hMAO-B-IN-6
CAS:<p>Compound 17d (hMAO-B-IN-6) is an effective and selective hMAO-B inhibitor, demonstrating an IC 50 of 67.02 nM. It significantly ameliorates cognitive deficits induced by Scopolamine in Alzheimer's disease (AD) mice [1].</p>Fórmula:C19H20N2O5Forma y color:SolidPeso molecular:356.37SSAO inhibitor-3
CAS:<p>SSAO inhibitor-3 targets human AOC1/SSAO in atherosclerosis, diabetes, obesity, CKD, and more, with IC50s of 0.1-10 μM/<10 nM.</p>Fórmula:C15H23FN4O3Forma y color:SolidPeso molecular:326.37Ifoxetine sulfate
CAS:<p>Ifoxetine sulfate, an atypical 5-HT inhibitor, may show unique therapeutic effects and side-effects.</p>Fórmula:C13H19NO2H2O4SPureza:98%Forma y color:SolidPeso molecular:270.34BChE-IN-9
CAS:<p>BChE-IN-9 (Azepano-11-deoxo-glycyrrhetol) is a hybrid BChE inhibitor (Ki: 0.21 μM).</p>Fórmula:C30H51NOForma y color:SolidPeso molecular:441.735-HT2A receptor agonist-2
CAS:<p>Potent 5-HT2A receptor agonist-2 targets 5-HT2A/B/C with EC50 1.7, 0.58, 0.50 nM.</p>Fórmula:C20H21ClN2O3Forma y color:SolidPeso molecular:372.85(RS)-4-Carboxyphenylglycine
CAS:<p>(RS)-4-Carboxyphenylglycine is a racemic mixture. (S)-4-Carboxyphenylglycine is a selective mGlu1α receptor antagonist.</p>Fórmula:C9H9NO4Pureza:99.04% - >99.99%Forma y color:SolidPeso molecular:195.17BMS-902483
CAS:<p>BMS-902483: potent α7 partial agonist; enhances rodent cognition; α7 EC50=9.3nM; 5-HT3A IC50=480nM.</p>Fórmula:C18H20N4OPureza:98%Forma y color:SolidPeso molecular:308.38Ph-HTBA
CAS:<p>Ph-HTBA: high-affinity CaMKIIα modulator, brain-penetrant, Kd 757 nM, used in ischemia/neurodegeneration research.</p>Fórmula:C19H18O3Forma y color:SolidPeso molecular:294.34Lofepramine hydrochloride
CAS:<p>Lofepramine is a serotonin and norepinephrine reuptake inhibitor. Lofepramine is also a psychotropic IMIPRAMINE derivative.</p>Fórmula:C26H28Cl2N2OPureza:98%Forma y color:Off-White SolidPeso molecular:455.42VU6001966
CAS:<p>VU6001966: potent, selective mGlu2 inhibitor (IC50=78 nM), negative modulator, with good CNS penetration.</p>Fórmula:C17H15FN4O2Pureza:98%Forma y color:SolidPeso molecular:326.33Aβ Fibrillization modulator 1
CAS:<p>Aβ Fibrillization Modulator 1 stabilizes amyloid-beta (Aβ) monomers, preventing their aggregation into fibrils.</p>Fórmula:C17H12N4O3SSeForma y color:SolidPeso molecular:431.33BMS-911172
CAS:<p>BMS-911172 is an adaptor associated kinase 1 (AAK1 kinase) inhibitor with an IC 50 of 35 nM.</p>Fórmula:C16H19F2N3O3Forma y color:SolidPeso molecular:339.34Tarafenacin D-tartrate
CAS:<p>Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.</p>Fórmula:C25H26F4N2O8Pureza:99.86%Forma y color:SolidPeso molecular:558.48Deramciclane fumarate
CAS:<p>Deramciclane fumarate is a 5-HT(2A/C) antagonist with putative anxiolytic activity.</p>Fórmula:C24H35NO5Forma y color:SolidPeso molecular:417.54ML352
CAS:<p>ML352 inhibits choline transporter noncompetitively; Ki of 92 nM in human CHT, 166 nM in mouse synaptosomes.</p>Fórmula:C21H29N3O4Pureza:99.15%Forma y color:SolidPeso molecular:387.47Methiothepin maleate
CAS:<p>Methiothepin maleate (Metitepine) is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.</p>Fórmula:C24H28N2O4S2Pureza:98%Forma y color:SolidPeso molecular:472.62S16961
CAS:<p>S16961 (S169611) is an agonist of nicotinic receptor.</p>Fórmula:C41H71NO6Pureza:99.69%Forma y color:SolidPeso molecular:674.01Afacifenacin
CAS:<p>Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.</p>Fórmula:C27H26F3N3O2Pureza:99.83%Forma y color:SolidPeso molecular:481.51AP521
CAS:<p>AP521 is an agonist of the human 5-HT1A receptor (IC50: 94 nM).</p>Fórmula:C20H19ClN2O3SPureza:98%Forma y color:SolidPeso molecular:402.89Donitriptan
CAS:<p>Donitriptan 是一种 5-HT 受体激动剂，对 5-HT1B 和 5-HT1D 的 pKi 分别为 9.4 和 9.3。</p>Fórmula:C23H25N5O2Pureza:98.76%Forma y color:SolidPeso molecular:403.48WAY208466 dihydrochloride
CAS:<p>WAY208466 dihydrochloride is a 5-HT6 receptor agonist (EC50=7.3 nM) with antidepressant and anxiolytic activity.</p>Fórmula:C17H20Cl2FN3O2SPureza:98.43%Forma y color:SolidPeso molecular:420.33GR 113808
CAS:<p>GR 113808 is a 5-HT4 receptor antagonist that inhibits 5-HT1B and 5-HT3 receptors and attenuates morphine-stimulated dopamine release in the rat striatum.</p>Fórmula:C19H27N3O4SPureza:98.16%Forma y color:SolidPeso molecular:393.5Foliglurax
CAS:<p>Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).</p>Fórmula:C23H23N3O3SPureza:98%Forma y color:SolidPeso molecular:421.51ASP2535
CAS:<p>ASP2535 is a potent, selective, orally bioavailable, brain permeable and centrally-active glycine transporter-1 (GlyT1) inhibitor.ASP2535 can improve cognitive</p>Fórmula:C22H18N6OPureza:98%Forma y color:SolidPeso molecular:382.42TC-N 22A
CAS:<p>TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier.</p>Fórmula:C14H13N5SPureza:99.95%Forma y color:SolidPeso molecular:283.35RO 4938581
CAS:<p>RO 4938581: potent GABAA α5 inverse agonist (Ki 4.6 nM); lower affinity for α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki: 174, 185, 80 nM).</p>Fórmula:C13H8BrF2N5Pureza:98%Forma y color:SolidPeso molecular:352.14Glemanserin
CAS:<p>Glemanserin (MDL11939) is a specific 5-HT2A antagonist with Ki values of 0.54 nM, 2.5 nM and 2.89 nM for rabbit, human and rat 5-HT2A.</p>Fórmula:C20H25NOPureza:99.93%Forma y color:SolidPeso molecular:295.42Aβ42-IN-2
CAS:<p>Aβ42-IN-2 is a γ-secretase modulator. Aβ42-IN-2 has an IC 50 of 6.5 nM for Αβ 42. Aβ42-IN-2 can be used for the Alzheimer's disease research[1].</p>Fórmula:C24H26N6O2Pureza:98.09% - 99.87%Forma y color:SolidPeso molecular:430.5RGH 1756
CAS:<p>RGH 1756 is an atypical antipsychotic with high affinity to dopamine D(3) receptors that leads to c-Fos induction in a unique pattern.</p>Fórmula:C26H30N4O2SPureza:98%Forma y color:SolidPeso molecular:462.61MFZ 10-7 hydrochloride
CAS:<p>MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAM</p>Fórmula:C15H10ClFN2Pureza:98%Forma y color:SolidPeso molecular:272.71Palonosetron
CAS:<p>Palonosetron, a 5-HT3 antagonist with Ki of 0.17 nM, is used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).</p>Fórmula:C19H24N2OPureza:98%Forma y color:SolidPeso molecular:296.41AF-DX 384 free base
CAS:<p>AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.</p>Fórmula:C27H38N6O2Pureza:98%Forma y color:SolidPeso molecular:478.63Astrophloxine
CAS:<p>Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue and</p>Fórmula:C27H33IN2Pureza:99.89%Forma y color:SolidPeso molecular:512.47AVN-322
CAS:<p>AVN-322 is a 5-HT6 receptor antagonist. 5-HT6R antagonists improves cognition in animal models of cognitive impairment.</p>Fórmula:C17H20ClN5O2SPureza:>99.99%Forma y color:SolidPeso molecular:393.89Phenoxypropazine
CAS:<p>Phenoxypropazine, a potent monoamine oxidase (MAO) inhibitor, is utilized in depression research.</p>Fórmula:C9H14N2OForma y color:SolidPeso molecular:166.22Ziprasidone mesylate trihydrate
CAS:<p>Ziprasidone mesylate hydrate is an oral 5-HT/D2 antagonist with Ki: D2=4.8nM, 5-HT2A=0.42nM, 5-HT1A=3.4nM in rats.</p>Fórmula:C22H31ClN4O7S2Forma y color:SolidPeso molecular:563.08Naronapride
CAS:<p>Naronapride (ATI-7505) is a potent agonist of the prokinetic 5-HT4receptor and can be used to study gastrointestinal disorders.</p>Fórmula:C27H41ClN4O5Forma y color:SolidPeso molecular:537.09Bopindolol (malonate)
CAS:<p>Bopindolol is a non-selective β-adrenergic receptor antagonist.</p>Fórmula:C26H32N2O7Forma y color:SolidPeso molecular:484.549PF-04781340
CAS:<p>PF-04781340 is an effective, selective, and CNS penetrant agonist of 5-HT2C receptor.</p>Fórmula:C17H21N3Pureza:98%Forma y color:SolidPeso molecular:267.37AChE/BuChE-IN-1
CAS:<p>AChE/BuChE-IN-1: BuChE inhibitor (IC50=0.48µM), weaker AChE blocker (IC50=7.16µM), ·OH scavenger (IC50=0.1674µM), may aid in AD research.</p>Fórmula:C19H19NO4Forma y color:SolidPeso molecular:325.36AFDX384
CAS:<p>AFDX384 is potent M2/M4 selective antagonist.</p>Fórmula:C28H42N6O5SForma y color:SolidPeso molecular:574.74VU6010572
CAS:<p>VU6010572: potent, selective mGlu3 modulator, IC50 245 nM, high CNS penetration.</p>Fórmula:C20H18FNO3Forma y color:SolidPeso molecular:339.36AChE-IN-12
CAS:<p>AChE-IN-12 inhibited rat/eel AChE, crossed BBB, prevented Aβ1-42 aggregation, and has potential for Alzheimer's research.</p>Fórmula:C33H41NO7Forma y color:SolidPeso molecular:563.68ZM 169369
CAS:<p>ICI 169369, a 5-HT2/5-HT1C antagonist, can evoke endothelium-dependent relaxation in rabbit aorta.</p>Fórmula:C19H20N2SForma y color:SolidPeso molecular:308.44Milameline hydrochloride
CAS:<p>Milameline hydrochloride is a Muscarinic receptor agonist.</p>Fórmula:C8H15ClN2OPureza:98%Forma y color:SolidPeso molecular:190.67
