Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(940 productos)
- ACK(1 productos)
- AChR(574 productos)
- ATP Citrato Liasa(16 productos)
- Receptor adrenérgico(2.942 productos)
- BACE(36 productos)
- Beta amiloide(204 productos)
- CAMK(68 productos)
- Inhibidores de ciclooxigenasa (COX)(562 productos)
- Receptor de dopamina(407 productos)
- Receptor GABA(336 productos)
- Gamma-secretasa(59 productos)
- GluR(255 productos)
- GlyT(24 productos)
- Receptor de histamina(358 productos)
- LRRK2(33 productos)
- Receptor de melatonina(24 productos)
- NMDAR(28 productos)
- Receptor de OX(40 productos)
- Receptor de opioides(296 productos)
Mostrar 12 subcategorías más
Se han encontrado 5400 productos de "Neurociencia"
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NCS-382 sodium
CAS:<p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>Fórmula:C13H13NaO3Pureza:98%Forma y color:SolidPeso molecular:240.235-HT2A&5-HT2C agonist-1
CAS:<p>5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.</p>Fórmula:C14H20N2OPureza:98%Forma y color:SolidPeso molecular:232.32AMPA receptor modulator-6
CAS:<p>AMPA receptor modulator-6, an AMPA receptor positive allosteric modulator (PAM), is utilized in the research of neurological diseases [1].</p>Fórmula:C24H36N2O4S2Pureza:98%Forma y color:SolidPeso molecular:480.68Nevadistinel
CAS:<p>Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, indicated for mitigating cognitive deficits</p>Fórmula:C15H18N2O3Pureza:98%Forma y color:SolidPeso molecular:274.32Brasofensine sulfate
CAS:<p>Brasofensine sulfate is a dopamine reuptake inhibitor.</p>Fórmula:C16H22Cl2N2O5SForma y color:SolidPeso molecular:425.33rel-HDMP 28 hydrochloride
CAS:<p>Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].</p>Fórmula:C18H22ClNO2Forma y color:SolidPeso molecular:319.83JM-1232
CAS:<p>JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.</p>Fórmula:C24H27N3O2Forma y color:SolidPeso molecular:389.49CGP-54626 free base
CAS:<p>CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).</p>Fórmula:C18H28Cl2NO3PPureza:98%Forma y color:SolidPeso molecular:408.3L-772,405
CAS:<p>L-772,405 is a highly selective agonists of h5-HT(1D) receptor.</p>Fórmula:C26H31FN6OPureza:98%Forma y color:SolidPeso molecular:462.56Adenylyl cyclase-IN-1
CAS:<p>Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].</p>Fórmula:C9H8N2S3Forma y color:SolidPeso molecular:240.37Physostigmine hemisulfate
CAS:<p>cholinesterase inhibitor</p>Fórmula:C15H21N302H204SPureza:98%Forma y color:SolidPeso molecular:324.39β-Secretase Inhibitor IV
CAS:<p>β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).</p>Fórmula:C31H38N4O5SPureza:98%Forma y color:SolidPeso molecular:578.72DU-125530
CAS:<p>DU-125530 is a 5-HT1A receptor antagonist.</p>Fórmula:C23H26ClN3O5SForma y color:SolidPeso molecular:491.99Yhhu-3792 hydrochloride
CAS:<p>Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].</p>Fórmula:C24H25ClN4O2Forma y color:SolidPeso molecular:436.933-Bromocytisine
CAS:<p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>Fórmula:C11H13BrN2OPureza:99.974%Forma y color:SolidPeso molecular:269.14(1α,1'S,4β)-Lanabecestat
CAS:<p>(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay),</p>Fórmula:C26H28N4OForma y color:SolidPeso molecular:412.53ASS234
CAS:<p>ASS234 is a multi-target propylamine used in the treatment of Alzheimer's disease.</p>Fórmula:C29H37N3OForma y color:SolidPeso molecular:443.62MTPG
CAS:<p>Group II/group III metabotropic glutamate receptor antagonist</p>Fórmula:C10H11N5O2Pureza:98%Forma y color:SolidPeso molecular:233.23AChE-IN-44
CAS:<p>AChE-IN-44 (Compound Tap4), an AChE inhibitor, is convertible into its thiazole salt form known as Tat2 [1].</p>Fórmula:C31H38ClN3OS2Forma y color:SolidPeso molecular:568.24Afizagabar
CAS:<p>Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.</p>Fórmula:C19H12FN3O2SForma y color:SolidPeso molecular:365.38mGAT-IN-1
CAS:<p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>Fórmula:C28H34ClN3O2S2Forma y color:SolidPeso molecular:544.17CGP 54626 hydrochloride
CAS:<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Fórmula:C18H29Cl3NO3PPureza:98%Forma y color:SolidPeso molecular:444.765-HT3 antagonist 1
CAS:<p>5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.</p>Fórmula:C22H27N5OPureza:98%Forma y color:SolidPeso molecular:377.48R-96544
CAS:<p>R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].</p>Fórmula:C22H30ClNO3Forma y color:SolidPeso molecular:391.93mGluR5 antagonist-1
CAS:<p>mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].</p>Fórmula:C23H18N4O2Forma y color:SolidPeso molecular:382.41Brasofensine
CAS:<p>Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.</p>Fórmula:C16H20Cl2N2OForma y color:SolidPeso molecular:327.25GSM-1
CAS:<p>GSM-1 is a modulator of γ-Secretase.</p>Fórmula:C26H31ClF3NO2Forma y color:SolidPeso molecular:481.98BACE-1 inhibitor 1
CAS:<p>BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).</p>Fórmula:C17H14BrF3N4O2Pureza:98%Forma y color:SolidPeso molecular:443.22Piperidine-4-sulfonic acid
CAS:<p>Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].</p>Fórmula:C5H11NO3SPureza:98%Forma y color:SolidPeso molecular:165.21GR 125487 sulfamate
CAS:<p>GR 125487 sulfamate is a 5-HT4 receptor antagonist.</p>Fórmula:C19H29FN4O8S2Pureza:98%Forma y color:SolidPeso molecular:524.58BMS-932481
CAS:<p>BMS-932481 is a γ-secretase modulator.</p>Fórmula:C24H24FN7OForma y color:SolidPeso molecular:445.49Anti-amyloid agent-1
CAS:<p>Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].</p>Fórmula:C21H17F3N2O3Forma y color:SolidPeso molecular:402.37MFZ 10-7
CAS:<p>MFZ 10-7 is anegative allosteric modulator of the mGluR5.</p>Fórmula:C15H9FN2Pureza:99.80%Forma y color:SolidPeso molecular:236.24CP-409092
CAS:<p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>Fórmula:C17H19N3O2Pureza:98%Forma y color:SolidPeso molecular:297.355-HT2A antagonist 1
CAS:<p>5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.</p>Fórmula:C26H28N4O2Pureza:98%Forma y color:SolidPeso molecular:428.53FPTQ
CAS:<p>FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1].</p>Fórmula:C17H12FN5Pureza:99.68% - 99.88%Forma y color:SolidPeso molecular:305.31L-AP4
CAS:<p>L-APB is an effective and specific agonist for the group III mGluRs (EC50s: 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6, and mGlu7 receptors, respectively).</p>Fórmula:C4H10NO5PPureza:98%Forma y color:White To Off-White Crystalline PowderPeso molecular:183.1TPA 023
CAS:<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Fórmula:C20H22FN7OPureza:99.75%Forma y color:SolidPeso molecular:395.435-HT3-In-1
CAS:<p>5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.</p>Fórmula:C16H21ClN4O3Pureza:98%Forma y color:SolidPeso molecular:352.82Zamifenacin fumarate
CAS:<p>Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.</p>Fórmula:C31H33NO7Pureza:99.88%Forma y color:SolidPeso molecular:531.6BMS 433796
CAS:<p>BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.</p>Fórmula:C21H20F2N4O4Pureza:99.17%Forma y color:SolidPeso molecular:430.4Osemozotan Free Base
CAS:<p>Osemozotan Free Base is a 5-HT(1A) receptor agonist.</p>Fórmula:C19H21NO5Forma y color:SolidPeso molecular:343.37Calmidazolium chloride
CAS:<p>Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.</p>Fórmula:C31H23Cl7N2OPureza:98.53%Forma y color:SolidPeso molecular:687.7A-424274
CAS:<p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>Fórmula:C14H15N3Pureza:98%Forma y color:SolidPeso molecular:225.29L 687306
CAS:<p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>Fórmula:C11H15N3OForma y color:SolidPeso molecular:205.26Capeserod HCl
CAS:<p>Capeserod HCl, a 5-hydroxytriptamine 4 (5-HT4) receptor agonist, is used potentially for the treatment of Alzheimer's disease.</p>Fórmula:C23H26Cl2N4O4Pureza:98%Forma y color:SolidPeso molecular:493.38LY 53857
CAS:<p>LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.</p>Fórmula:C27H36N2O7Forma y color:SolidPeso molecular:500.592PHP 501 trifluoroacetate
CAS:<p>GABAA antagonist</p>Fórmula:C20H21N3OPureza:98%Forma y color:SolidPeso molecular:319.4FGIN-1-27
CAS:<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Fórmula:C28H37FN2OPureza:99.86%Forma y color:SolidPeso molecular:436.6BMS-933043
CAS:<p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>Fórmula:C16H19N7OPureza:98%Forma y color:SolidPeso molecular:325.37
