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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5400 productos de "Neurociencia"

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  • Tebideutorexant
    Targetmol
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    Tebideutorexant

    CAS:
    <p>Tebideutorexant, an orexin-1 receptor antagonist, shows anti-panic effects in rodents and humans, providing a tool for stress response and psychiatric research.</p>
    Fórmula:C23H16D2F4N4O2
    Pureza:98.89%
    Forma y color:Solid
    Peso molecular:460.42

    Ref: TM-T70332

  • hMAO-B-IN-10
    Targetmol
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    hMAO-B-IN-10

    <p>hMAO-B-IN-10 (compound 7) is an inhibitor of MAO-A/B with IC50 values of 424.1 nM and 177.9 nM, respectively. It has demonstrated neuroprotective effects in the MPTP-induced mouse model of Parkinson's Disease (PD).</p>
    Fórmula:C16H12N4O4
    Forma y color:Solid
    Peso molecular:324.29

    Ref: TM-T201531

  • Relicpixant
    Targetmol
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    Relicpixant

    CAS:
    <p>Relicpixant is a potent purine receptor (P2X) antagonist.</p>
    Fórmula:C20H19ClF2N4O5S
    Forma y color:Solid
    Peso molecular:500.9

    Ref: TM-T200883

  • AChE/BuChE-IN-3
    Targetmol
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    AChE/BuChE-IN-3

    CAS:
    <p>AChE/BuChE-IN-3 inhibits AChE (IC50: 0.65 μM), BuChE (IC50: 5.77 μM), crosses BBB, and hinders Aβ1-42 aggregation for Alzheimer's research.</p>
    Fórmula:C30H30F3N3O6
    Forma y color:Solid
    Peso molecular:585.57

    Ref: TM-T64137

  • Logo de CymitQuimica
    Targetmol
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    MAO-B-IN-6

    <p>MAO-B-IN-6 is a selective, potent, orally active MAO-B inhibitor (IC50: 0.019 μM). MAO-B-IN-6 is superior to Safinamide both in vitro and in vivo.</p>
    Forma y color:Solid

    Ref: TM-T64271

  • BF-168
    Targetmol
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    BF-168

    CAS:
    <p>BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).</p>
    Fórmula:C18H17FN2O2
    Forma y color:Solid
    Peso molecular:312.34

    Ref: TM-T10529

  • CB2R/5-HT1AR agonist 1
    Targetmol
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    CB2R/5-HT1AR agonist 1

    CAS:
    <p>Compound 2o, also known as CB2R/5-HT1AR agonist 1, serves as a partial orally active agonist for the CB2 receptor (EC50 = 479.6 nM) and a full agonist for the 5-HT1A receptor (EC50 = 2.7 μM). This compound demonstrates both anti-anxiety and anti-depressive effects and has favorable pharmacokinetic properties [1].</p>
    Fórmula:C24H33NO3
    Forma y color:Solid
    Peso molecular:383.52

    Ref: TM-T86012

  • RTIOXA-43
    Targetmol
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    RTIOXA-43

    CAS:
    <p>RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.</p>
    Fórmula:C37H37N5O5S
    Pureza:99.17%
    Forma y color:Solid
    Peso molecular:663.79

    Ref: TM-T87345

  • Logo de CymitQuimica
    Targetmol
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    ChE/Aβ1-42-IN-1

    <p>ChE/Aβ1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Aβ 1-42 with excellent BBB permeability.</p>
    Fórmula:C19H24N2O3
    Forma y color:Solid
    Peso molecular:328.41

    Ref: TM-T60940

  • AAZ-A 154 mesylate
    Targetmol
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    AAZ-A 154 mesylate

    CAS:
    <p>AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.</p>
    Fórmula:C15H24N2O4S
    Forma y color:Solid
    Peso molecular:328.43

    Ref: TM-T200486

  • CL-13
    Targetmol
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    CL-13

    <p>CL-13 is an inhibitor of butyrylcholinesterase (BChE), exhibiting an IC50 of 1.15 μM and a selectivity index (SI) of 9.2 for acetylcholinesterase. It demonstrates antioxidative activity in SH-SY5Y cells with a DPPHEC50 of 47.01 μM and has the capacity to chelate metals involved in Aβ aggregation and/or oxidative stress, showing no neurotoxicity at concentrations up to 50 μM. CL-13 can also reverse scopolamine-induced cognitive impairments without affecting motor abilities in mice.</p>
    Fórmula:C29H32N4OS
    Forma y color:Solid
    Peso molecular:484.66

    Ref: TM-T201512

  • Logo de CymitQuimica
    Targetmol
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    K027

    <p>K027 is a potent organophosphate (OP) inhibitor of acetylcholinesterase (AChE) reactivation. k027 can be used to study Alzheimer's disease.</p>
    Fórmula:C15H18Br2N4O2
    Forma y color:Solid
    Peso molecular:446.14

    Ref: TM-T62634

  • Logo de CymitQuimica
    Targetmol
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    γ-secretase modulator 5

    <p>Compound 22d is a GSM that crosses the blood-brain barrier, inhibits Aβ42 production (IC50: 60 nM), and may help study Alzheimer's.</p>
    Forma y color:Solid

    Ref: TM-T64258

  • TDI-11861
    Targetmol
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    TDI-11861

    CAS:
    <p>TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.</p>
    Fórmula:C22H25ClF2N6O3
    Forma y color:Solid
    Peso molecular:494.92

    Ref: TM-T73297

  • Nafimidone hydrochloride
    Targetmol
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    Nafimidone hydrochloride

    CAS:
    <p>Nafimidone hydrochloride, an antiepileptic agent, inhibits acetylcholinesterase, protects neurons, and ameliorates cognitive decline. It is utilized in epilepsy research.</p>
    Fórmula:C15H13ClN2O
    Forma y color:Solid
    Peso molecular:272.73

    Ref: TM-T201733

  • MADAM
    Targetmol
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    MADAM

    CAS:
    <p>MADAM demonstrates high affinity and selectivity for 5-HTT, with a Ki value of 1.6 nM. It is utilized as a PET radiotracer for visualizing serotonin transporters.</p>
    Fórmula:C16H20N2S
    Forma y color:Solid
    Peso molecular:272.408

    Ref: TM-T204693

  • AChE/BChE-IN-24
    Targetmol
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    AChE/BChE-IN-24

    CAS:
    <p>AChE/BChE-IN-24 (compound 5k) functions as a neuroprotective agent by inhibiting acetylcholinesterase. It targets both AChE and BChE, demonstrating IC50 values of 16.38 μM and 10.44 μM, respectively.</p>
    Fórmula:C20H21N3
    Forma y color:Solid
    Peso molecular:303.4

    Ref: TM-T201846

  • LY593093
    Targetmol
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    LY593093

    CAS:
    <p>LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.</p>
    Fórmula:C32H30FN3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:507.6

    Ref: TM-T27961

  • LRRK2-IN-2
    Targetmol
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    LRRK2-IN-2

    CAS:
    <p>LRRK2-IN-2: selective, potent LRRK2 inhibitor, IC50 of 0.6 nM, oral, crosses blood-brain barrier, for Parkinson's research.</p>
    Fórmula:C23H23Cl2F3N6O2
    Forma y color:Solid
    Peso molecular:543.37

    Ref: TM-T63824

  • Logo de CymitQuimica
    Targetmol
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    BACE1-IN-8

    <p>BACE1-IN-8 is a potent inhibitor of BACE1 (β-site APP lyase 1) (IC50: 3.9 μM).</p>
    Fórmula:C29H45N5O7
    Forma y color:Solid
    Peso molecular:575.7

    Ref: TM-T64074