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Proteasas / Proteasoma

Proteasas / Proteasoma

Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.

Subcategorías de "Proteasas / Proteasoma"

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Se han encontrado 1094 productos de "Proteasas / Proteasoma"

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  • MK-0608

    CAS:
    MK-0608 is an orally bioavailable HCV replication inhibitor in vitro(EC50 = 0.3 μM and EC90=1.3 μM in the subgenomic-replicon assay).
    Fórmula:C12H16N4O4
    Pureza:98.48%
    Forma y color:Solid
    Peso molecular:280.28
  • Trelagliptin

    CAS:
    Trelagliptin (SYR-472) is a highly specific and long-acting DPP-4 inhibitor.
    Fórmula:C18H20FN5O2
    Pureza:98.88%
    Forma y color:Solid
    Peso molecular:357.38
  • Sitagliptin

    CAS:
    Sitagliptin (MK0431), an oral DPP-4 inhibitor, treats type 2 diabetes alone or with metformin/thiazolidinedione by increasing incretins and insulin.
    Fórmula:C16H15F6N5O
    Pureza:99.33% - 99.83%
    Forma y color:Yellow Grease
    Peso molecular:407.31
  • Elsulfavirine

    CAS:
    Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.
    Fórmula:C24H17BrCl2FN3O5S
    Pureza:99.66%
    Forma y color:Solid
    Peso molecular:629.28
  • LDN-27219

    CAS:
    LDN-27219 is a potent hTGase inhibitor with IC50 of 0.6 uM.
    Fórmula:C20H16N4O2S2
    Pureza:99.01% - 99.38%
    Forma y color:Solid
    Peso molecular:408.5
  • RAMB4

    CAS:
    RAMB4 (PTP1B-IN-9) is a ubiquitin-proteasome system (UPS)-stressor,with anticancer activity.
    Fórmula:C19H13Cl4NO
    Pureza:98.89% - 99.38%
    Forma y color:Solid
    Peso molecular:413.12
  • Sofosbuvir impurity G

    CAS:
    Sofosbuvir impurity G is both a diastereomer of Sofosbuvir and an impurity of Sofosbuvir which is an inhibitor of HCV RNA replication.
    Fórmula:C22H29FN3O9P
    Pureza:98.04%
    Forma y color:Solid
    Peso molecular:529.45
  • BJJF078

    CAS:
    BJJF078, an aminopiperidine, inhibits human/mouse TG2 (IC50: 41/54 nM) and TG1 (IC50: 0.16 μM), may be used in MS studies.
    Fórmula:C27H29N3O6S
    Pureza:99.56%
    Forma y color:Soild
    Peso molecular:523.6
  • BRD-6929

    CAS:
    BRD-6929, a brain-targeted HDAC1/2 inhibitor (IC50 1/8 nM), enhances gnidimacrin's anti-HIV effect, useful in mood behavior studies.
    Fórmula:C19H17N3O2S
    Pureza:98.01% - 99.05%
    Forma y color:Solid
    Peso molecular:351.42
  • Islatravir

    CAS:
    Islatravir (MK-8591) is an effective anti-HIV-1 agent.
    Fórmula:C12H12FN5O3
    Pureza:98.77%
    Forma y color:Solid
    Peso molecular:293.25
  • Probenecid

    CAS:
    <p>Probenecid (Benemid) is a benzoic acid derivative with antihyperuricemic property.</p>
    Fórmula:C13H19NO4S
    Pureza:98.95% - 99.84%
    Forma y color:Crystals From Dil Alcohol Pleasant Aftertaste (Ntp 1992)
    Peso molecular:285.36
  • Ruzasvir

    CAS:
    Ruzasvir (MK-8408) is a novel and potent pan-genotypic inhibitor of hepatitis C virus NS5A with antiviral activity.
    Fórmula:C49H55FN10O7S
    Pureza:96.87% - 99.93%
    Forma y color:Solid
    Peso molecular:947.09
  • LSP-249

    CAS:
    <p>LSP-249 is a plasma kallikrein inhibitor under the study for angioedema, with an EC50 less than 100 nM in cell.</p>
    Fórmula:C24H22ClN5O
    Pureza:99.51%
    Forma y color:Solid
    Peso molecular:431.92
  • ML604440

    CAS:
    ML604440 is a cell permeable proteasome β1i (LMP2) subunit inhibitor.
    Fórmula:C17H24BF3N2O4
    Pureza:97.06%
    Forma y color:Solid
    Peso molecular:388.19
  • Q-VD-OPH

    CAS:
    <p>Q-VD-OPh is an irreversible caspase inhibitor with an IC50 value of 48 nM against caspase-7 and between 25 and 400 nM against caspase-1, 3, 8, 9, 10, 12.</p>
    Fórmula:C26H25F2N3O6
    Pureza:97.8% - 98.95%
    Forma y color:Solid
    Peso molecular:513.5
  • Ref: IN-DA0048C1

    1mg
    50,00€
    5mg
    50,00€
    25mg
    155,00€
    50mg
    197,00€
    100mg
    331,00€
    250mg
    531,00€
  • Ref: IN-DA0072SK

    1g
    A consultar
    5mg
    68,00€
    10mg
    90,00€
    25mg
    124,00€
    50mg
    168,00€
    100mg
    229,00€
    250mg
    500,00€
    500mg
    A consultar
  • Avoralstat

    CAS:
    Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema.
    Fórmula:C28H27N5O5
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:513.54
  • Mecarbinate

    CAS:
    Mecarbinate (Dimecarbin) is arbidol hydrochloride's chemical intermediate.
    Fórmula:C13H15NO3
    Pureza:99.28%
    Forma y color:Off-White Crystalline Powder
    Peso molecular:233.26
  • Sofosbuvir impurity F

    CAS:
    <p>Sofosbuvir impurity F (Sofosbuvir 3',5'-Bis-(S)-phosphate) is both a diastereomer of Sofosbuvir and an impurity of Sofosbuvir which is an inhibitor of HCV RNA</p>
    Fórmula:C34H45FN4O13P2
    Pureza:98.05%
    Forma y color:Solid
    Peso molecular:798.69