Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(36 productos)
- Cisteína proteasa(110 productos)
- DPP-4(23 productos)
- Glutaminasa(44 productos)
- Proteasa del VIH(495 productos)
- PAI-1(26 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(54 productos)
- Proteasoma(88 productos)
- Serina proteasa(51 productos)
- p97(15 productos)
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Se han encontrado 998 productos de "Proteasas / Proteasoma"
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ABT-518
CAS:ABT-518 is an inhibitor of matrix metalloproteinases, which are associated with tumor growth and development of metastasis.Fórmula:C21H22F3NO8SForma y color:SolidPeso molecular:505.46ACH-806
CAS:ACH-806 is an NS4A antagonist. It can inhibit Hepatitis C Virus (HCV) replication with an EC50 of 14 nM.Fórmula:C19H20F3N3O2SPureza:98%Forma y color:SolidPeso molecular:411.44MK-2048
CAS:MK-2048 is a potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.Fórmula:C21H21ClFN5O4Pureza:98%Forma y color:SolidPeso molecular:461.87AZD-1236
CAS:AZD1236 is a selective inhibitor for human MMP-9/MMP-12, less effective in rodents, and reduces lung injury and inflammation.Fórmula:C15H19ClN4O5SForma y color:SolidPeso molecular:402.85Butabindide
CAS:Butabindide (UCL-1397) selectively inhibits TPP II, protecting CCK-8, with Ki of 10 μM (TPP I) and 7 nM (TPP II).Fórmula:C17H25N3O2Forma y color:SolidPeso molecular:303.4GM 1489
CAS:GM 1489 is an MMP inhibitor, effective against MMP-1, -2, -3, -8, -9, reduces cancer cell invasion, and prevents ear thickening in mice.Fórmula:C27H33N3O4Forma y color:SolidPeso molecular:463.57GSK2793660 free base
CAS:GSK-2793660, a cathepsin C inhibitor, may treat cystic fibrosis and related lung conditions.Fórmula:C22H31N3O3Forma y color:SolidPeso molecular:385.5THDP-17
CAS:THDP-17 is a inhibitor of glutaminase. THDP-17 shows a partial uncompetitive inhibition in vitro.Fórmula:C12H16N2SPureza:98%Forma y color:SolidPeso molecular:220.33Garvagliptin
CAS:Garvagliptin has antidiabetic activity.Fórmula:C18H23F2N3O3SPureza:98%Forma y color:SolidPeso molecular:399.46Cysteine protease inhibitor-2
CAS:Cysteine protease inhibitor from US20070032499A1; halts DCT116 at 6.5μM, PC3 at 4.4μM.Fórmula:C13H5N5OPureza:98%Forma y color:SolidPeso molecular:247.21TPO agonist 1
CAS:TPO agonist 1, Thrombopoietin (TPO) mimetic, promotes platelet/megakaryocyte production, for thrombocytopenia research.Fórmula:C25H22N8O2Pureza:98%Forma y color:SolidPeso molecular:466.49ZD8321
CAS:ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).Fórmula:C18H28F3N3O5Pureza:98%Forma y color:SolidPeso molecular:423.43Proteasome-IN-1
CAS:Proteasome-IN-1 is an inhibitor of proteasome.Fórmula:C42H35N5O3Pureza:98%Forma y color:SolidPeso molecular:657.76TAPI-1
CAS:TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.Fórmula:C26H37N5O5Pureza:≥95%Forma y color:SolidPeso molecular:499.6GS-9256
CAS:GS-9256 is a selective inhibitor of the HCV NS3 protease, exhibiting favorable pharmacokinetic properties and antiviral activity [1].Fórmula:C46H56ClF2N6O8PSPureza:98%Forma y color:SolidPeso molecular:957.46Z-LLF-CHO
CAS:Z-LLF-CHO (Z-Leu-Leu-Phe-CHO) effectively inhibits the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex with a Ki value of 460 nM.Fórmula:C29H39N3O5Pureza:98%Forma y color:SolidPeso molecular:509.64MMP13-IN-4
CAS:MMP13-IN-4 (compound 13) is a potent, selective MMP-13 inhibitor with an IC50 of 14.6 μM, implicated in the pathology of osteoarthritis (OA) [1].Fórmula:C21H17BrN4O5Pureza:98%Forma y color:SolidPeso molecular:485.29ND-322 HCl
CAS:ND-322 HCl (ND 322 Hydrochloride) is a selective inhibitor of MT1-MMP and MMP2 and reduces in vitro melanoma cell growth, migration and invasion.Fórmula:C15H16ClNO3S2Pureza:99.49%Forma y color:SolidPeso molecular:357.88Ref: TM-T28145
1mg152,00€5mg334,00€10mg492,00€25mg780,00€50mg1.044,00€100mg1.414,00€1mL*10mM (DMSO)349,00€PF-00356231 hydrochloride
CAS:PF-00356231 hydrochloride is an inhibitor of matrix metalloproteinase MMP-12 with IC50 of 1.4 μM.Fórmula:C25H21ClN2O3SPureza:98.39%Forma y color:SolidPeso molecular:464.96NNGH
CAS:NNGH is a matrix metalloproteinase 3 (MMP-3) inhibitor with anticancer activity that counteracts the inhibitory effects of E2 and DHT on RANKL membrane-binding.Fórmula:C13H20N2O5SPureza:98.41%Forma y color:SolidPeso molecular:316.37
