Proteasas / Proteasoma
Los inhibidores de proteasas y proteasomas son compuestos que bloquean la actividad de las proteasas y del proteasoma, que están involucrados en la degradación y renovación de proteínas. Estos inhibidores son vitales para estudiar la regulación de la homeostasis proteica, el control del ciclo celular y la apoptosis. Los inhibidores de proteasas y proteasomas también se utilizan en el tratamiento de enfermedades como el cáncer, donde la degradación anormal de proteínas desempeña un papel en la progresión de la enfermedad. Al inhibir las proteasas o el proteasoma, estos compuestos pueden inducir la muerte celular en células cancerosas y son herramientas esenciales tanto en la investigación básica como en el desarrollo terapéutico. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteasas y proteasomas de alta calidad para apoyar su investigación en bioquímica, biología celular y desarrollo de fármacos.
Subcategorías de "Proteasas / Proteasoma"
- Acetil-CoA Carboxilasa(36 productos)
- Cisteína proteasa(110 productos)
- DPP-4(24 productos)
- Glutaminasa(44 productos)
- Proteasa del VIH(496 productos)
- PAI-1(26 productos)
- Inhibidores de la proteasa(50 productos)
- Receptor activado por proteasa(54 productos)
- Proteasoma(87 productos)
- Serina proteasa(51 productos)
- p97(15 productos)
Mostrar 3 subcategorías más
Se han encontrado 992 productos de "Proteasas / Proteasoma"
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Ro 32-7315
CAS:Ro 32-7315 is a selective inhibitor of ADAM17.Fórmula:C22H35N3O5SPureza:98%Forma y color:SolidPeso molecular:453.6LU-005i
CAS:LU-005i is a powerful inhibitor targeting the β5i subunit of immunoproteasomes, displaying a high potency with an IC 50 value of 6.6 nM, and exhibits selectivity by preferring β5i over the β5c subunit, which has an IC 50 value of 287 nM [1].Fórmula:C31H46N4O7Forma y color:SolidPeso molecular:586.72GSK-2485852
CAS:GSK-2485852, a NS5B inhibitor, is used potentially for treatment of HCV infection.Fórmula:C27H25BF2N2O6SForma y color:SolidPeso molecular:554.37XL-784 free base
CAS:XL-784 free base selectively inhibits MMPs with IC50: MMP-1 (1.9µM), MMP-2 (0.81nM), MMP-3 (120nM), MMP-8 (10.8nM), MMP-9 (18nM), MMP-13 (0.56nM).Fórmula:C21H22ClF2N3O8SPureza:98%Forma y color:SolidPeso molecular:549.93MDL-101146, (R)-
CAS:MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.Fórmula:C29H37F5N4O6Pureza:98%Forma y color:SolidPeso molecular:632.62SSR 69071
CAS:SSR69071: selective neutrophil elastase inhibitor, stronger for humans (Ki=0.0168 nM), may treat COPD, asthma, and reduce heart injury.Fórmula:C27H32N4O7SForma y color:SolidPeso molecular:556.63LONP1-IN-2
CAS:LONP1-IN-2: Potent LONP1 inhibitor, IC50=0.187μM; weak on 20S proteasome (>10μM); for cancer research.Fórmula:C16H27BN4O4Forma y color:SolidPeso molecular:350.22MMP3 inhibitor 1
CAS:MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).Fórmula:C23H31N3O6SPureza:98%Forma y color:SolidPeso molecular:477.57Phe-Pro-Ala-pNA
CAS:Phe-Pro-Ala-pNA is a chromogenic substrate utilized for assessing tripeptidyl peptidase activity.Fórmula:C23H27N5O5Forma y color:SolidPeso molecular:453.49Flovagatran sodium
CAS:Flovagatran sodium, a thrombin inhibitor, is used potentially for the treatment of thrombosis.Fórmula:C27H36BN3NaO7Pureza:98%Forma y color:SolidPeso molecular:548.4MDL 27324
CAS:MDL 27324 is an inhibitor of human neutrophil elastase.Fórmula:C29H38F3N5O6SPureza:98%Forma y color:SolidPeso molecular:641.7LMP7-IN-2
CAS:LMP7-IN-2 is an inhibitor of LMP7 and may be utilized in the treatment of associated inflammatory diseases and disorders [1].Fórmula:C28H27N3O3SForma y color:SolidPeso molecular:485.6MMP-7-IN-3
CAS:MMP-7-IN-3 (compound 15) is a potent and selective MMP-7 inhibitor, inhibiting renal fibrosis in a unilateral ureteral obstruction mouse model.Fórmula:C34H43ClF3N7O9SPureza:99.915%Forma y color:SolidPeso molecular:818.26BAY-678
CAS:BAY-678: Oral selective human neutrophil elastase inhibitor; IC50: 20 nM; SGC-approved chemical probe.Fórmula:C20H15F3N4O2Pureza:99.36%Forma y color:SolidPeso molecular:400.35Ref: TM-T10473
5mg37,00€10mg60,00€25mg119,00€50mg173,00€100mg264,00€200mg374,00€1mL*10mM (DMSO)42,00€Z-FG-NHO-BzOME
CAS:Z-FG-NHO-BzOME is a chemical compound functioning as a cysteine protease inhibitor, selectively targeting and inhibiting cathepsin B, cathepsin L, cathepsin S,Fórmula:C27H27N3O7Forma y color:SolidPeso molecular:505.52KB-R7785
CAS:KB-R7785 is a novel ADAM12/MMP inhibitor improving heart function and insulin sensitivity by blocking HB-EGF and TNF-alpha.Fórmula:C18H27N3O4Forma y color:SolidPeso molecular:349.42BAY-320
CAS:BAY-320 is a Bub1 inhibitor. With an IC50 of 680 nM for human Bub1 in the presence of 2 mM ATP.Fórmula:C26H26F2N6O2Pureza:98%Forma y color:SolidPeso molecular:492.52MDL 101146
CAS:MDL 101146 is an orally active neutrophil elastase inhibitor.Fórmula:C29H37F5N4O6Pureza:98%Forma y color:SolidPeso molecular:632.62O-Benzoylhydroxylamine
CAS:O-Benzoyl hydroxylamine exhibits properties as a dipeptidyl peptidase-IV (DPP-IV) inhibitor and demonstrates antidiabetic effects[1].Fórmula:C7H7NO2Forma y color:SolidPeso molecular:137.14Mergetpa
CAS:Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].Fórmula:C7H15N3O2S2Pureza:98%Forma y color:SolidPeso molecular:237.34
