CymitQuimica logo
Tirosina quinasa / adaptadores

Tirosina quinasa / adaptadores

Los inhibidores de tirosina quinasa y adaptadores son compuestos que se dirigen a las tirosina quinasas y sus proteínas adaptadoras asociadas, las cuales desempeñan roles cruciales en la señalización celular, el crecimiento y la diferenciación. Estos inhibidores son herramientas esenciales en la investigación del cáncer, ya que muchas tirosina quinasas están involucradas en las vías de señalización que impulsan el crecimiento tumoral y la metástasis. Al inhibir las tirosina quinasas, estos compuestos pueden bloquear cascadas de señalización críticas, ofreciendo potenciales estrategias terapéuticas para varios tipos de cáncer y otras enfermedades que implican una señalización celular anormal. En CymitQuimica, ofrecemos una amplia gama de inhibidores de tirosina quinasa y adaptadores de alta calidad para apoyar su investigación en oncología, biología molecular y desarrollo de terapias dirigidas.

Subcategorías de "Tirosina quinasa / adaptadores"

Mostrar 13 subcategorías más

Se han encontrado 1342 productos de "Tirosina quinasa / adaptadores"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
productos por página.
  • CG 428
    Targetmol
    + Info

    CG 428

    CAS:
    <p>CG 428 is a potent tropomyosin receptor Kinase (TRK) Degrader (uSMITETM) with a DC50 of 0.36 nM.</p>
    Fórmula:C43H43FN10O6
    Pureza:99.83%
    Forma y color:Solid
    Peso molecular:814.86

    Ref: TM-T41224

  • Edralbrutinib
    Targetmol
    + Info

    Edralbrutinib

    CAS:
    <p>Edralbrutinib (TG-1701) is a potent BTK inhibitor with anticancer activity and is used in the treatment of tumors, immune system disorders, and blood and</p>
    Fórmula:C26H21F2N5O3
    Pureza:99.41%
    Forma y color:Solid
    Peso molecular:489.47

    Ref: TM-T63272

  • TYRA-300
    Targetmol
    + Info

    TYRA-300

    CAS:
    <p>TYRA-300 is an oral and selective FGFR3 inhibito, in the Ba/F3 cell line for the treatment of metastatic uroepithelial carcinomas (mUCs) and chondrodysplasia.</p>
    Fórmula:C25H24Cl2N6O3S
    Pureza:99.66%
    Forma y color:Solid
    Peso molecular:559.47

    Ref: TM-T88841

  • DYRKs-IN-2
    Targetmol
    + Info

    DYRKs-IN-2

    CAS:
    <p>DYRKs-IN-2 has antitumor activity. DYRKs-IN-2 is a potent DYRKs inhibitor with IC50s of 30.6 nM and 12.8 nM for DYRK1B and DYRK1A, respectively.</p>
    Fórmula:C32H38ClN9O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:632.16

    Ref: TM-T11133

  • c-met-IN-1
    Targetmol
    + Info

    c-met-IN-1

    CAS:
    <p>c-met-IN-1 is a potent and selective c-Met inhibitor (IC50: 1.1 nM) with antitumor activity.</p>
    Fórmula:C35H37FN6O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:640.7

    Ref: TM-T10653

  • HKI-357
    Targetmol
    + Info

    HKI-357

    CAS:
    <p>HKI-357 irreversibly inhibits EGFR/ERBB2 (IC50: 34/33 nM), blocks EGFR Y1068 autophosphorylation, and AKT/MAPK phosphorylation.</p>
    Fórmula:C31H29ClFN5O3
    Pureza:99.91%
    Forma y color:Solid
    Peso molecular:574.05

    Ref: TM-T11569

  • BMX-IN-1
    Targetmol
    + Info

    BMX-IN-1

    CAS:
    <p>BMX-IN-1 (BMX kinase inhibitor) is a selective inhibitor of bone marrow tyrosine kinase on chromosome X (BMX, IC50 = 8 nM) and the related Bruton’s tyrosine</p>
    Fórmula:C29H24N4O4S
    Pureza:98.38%
    Forma y color:Solid
    Peso molecular:524.59

    Ref: TM-T14692

  • PF-06250112
    Targetmol
    + Info

    PF-06250112

    CAS:
    <p>PF-06250112 is an effective and highly selective BTK inhibitor (IC50: 0.5 nM.</p>
    Fórmula:C22H20F2N6O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:438.43

    Ref: TM-T12673L

  • PF-06459988
    Targetmol
    + Info

    PF-06459988

    CAS:
    PF-06459988 is a novel, effective, orally active, irreversible, and selective epidermal growth factor receptor (EGFR) mutant inhibitor.
    Fórmula:C19H22ClN7O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:431.88

    Ref: TM-T16492

  • EGFR-IN-30
    Targetmol
    + Info

    EGFR-IN-30

    CAS:
    <p>EGFR-IN-30 is an EGFR inhibitor (IC50: 1-10 nM, &lt;1 nM WT/mutants) with potential in cancer research.</p>
    Fórmula:C28H33BrN7O2P
    Forma y color:Solid
    Peso molecular:610.49

    Ref: TM-T73108

  • HER2-IN-5
    Targetmol
    + Info

    HER2-IN-5

    CAS:
    <p>HER2-IN-5 is an effective inhibitor of orally active HER-2.</p>
    Fórmula:C27H33N7O3
    Forma y color:Solid
    Peso molecular:503.6

    Ref: TM-T63432

  • Nazartinib S-enantiomer
    Targetmol
    + Info

    Nazartinib S-enantiomer

    CAS:
    <p>Nazartinib is an EGFR inhibitor. Nazartinib S-enantiomer is the less active S-enantiomer of Nazartinib.</p>
    Fórmula:C26H31ClN6O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:495.02

    Ref: TM-T11156

  • MS 154
    Targetmol
    + Info

    MS 154

    CAS:
    MS 154 is a potent PROTAC® targeting mutant EGFR in lung cancer, sparing WT-EGFR; effective in mice, with DC50 of 11-25 nM.
    Fórmula:C46H54ClFN8O8
    Forma y color:Solid
    Peso molecular:901.42

    Ref: TM-T41155

  • TL02-59
    Targetmol
    + Info

    TL02-59

    CAS:
    <p>TL02-59: Fgr inhibitor (IC50=0.03nM), also targets Lyn (0.1nM), Hck (160nM), halts acute myelogenous leukemia growth.</p>
    Fórmula:C32H34F3N5O4
    Pureza:98.77%
    Forma y color:Solid
    Peso molecular:609.64

    Ref: TM-T13186

  • EGFR-IN-32
    Targetmol
    + Info

    EGFR-IN-32

    CAS:
    <p>EGFR-IN-32, a potent EGFR blocker, shows promise for EGFR-mutated illnesses. (Patent WO2021185297A1, compound 2)</p>
    Fórmula:C31H34N6O3
    Forma y color:Solid
    Peso molecular:538.64

    Ref: TM-T63798

  • Vepafestinib
    Targetmol
    + Info

    Vepafestinib

    CAS:
    <p>Vepafestinib is a RET inhibitor with potential antineoplastic activity[1].</p>
    Fórmula:C26H30N6O3
    Pureza:98.56%
    Forma y color:Solid
    Peso molecular:474.55

    Ref: TM-T9445

  • OTS447
    Targetmol
    + Info

    OTS447

    CAS:
    <p>OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .</p>
    Fórmula:C27H32ClN3O2
    Pureza:98.78%
    Forma y color:Solid
    Peso molecular:466.02

    Ref: TM-T62979

  • FGFR3-IN-6
    Targetmol
    + Info

    FGFR3-IN-6

    CAS:
    <p>FGFR3-IN-6 is a potent, selective inhibitor of FGFR 3, exhibiting an IC50 value of less than 350 nM , and is utilized in cancer research [1].</p>
    Fórmula:C25H23FN8O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:486.5

    Ref: TM-T82405

  • Labuxtinib
    Targetmol
    + Info

    Labuxtinib

    CAS:
    <p>Labutinib is a selective inhibitor of the c-kit tyrosine kinase [1].</p>
    Fórmula:C20H16FN5O2
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:377.37

    Ref: TM-T79851

  • c-Fms-IN-14
    Targetmol
    + Info

    c-Fms-IN-14

    CAS:
    <p>c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].</p>
    Fórmula:C26H24N6O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:436.51

    Ref: TM-T79815