Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 707 productos de "Síntesis de ADN / ARN"
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Nedaplatin
CAS:<p>Nedaplatin, a cisplatin derivative, induces tumor DNA damage (IC50: 94 μM) through platinum-DNA cross-links, causing apoptosis.</p>Fórmula:C2H8N2O3PtPureza:99.88% - >99.99%Forma y color:Straw Yellow PowderPeso molecular:303.17DNA2 inhibitor C5
CAS:<p>DNA2 inhibitor C5 is a specific cancer sensitizer with an IC50 of 20 μM, targeting multiple DNA2 activities.</p>Fórmula:C10H6N2O5Pureza:99.05%Forma y color:SolidPeso molecular:234.16Capecitabine
CAS:<p>Capecitabine is a prodrug in the antimetabolite class, transformed into cytotoxic 5-FU by tumor cells, inhibiting DNA and RNA synthesis.</p>Fórmula:C15H22FN3O6Pureza:99.81% - >99.99%Forma y color:Less Solid Colourless SolidPeso molecular:359.35BMVC-8C3O
CAS:<p>BMVC-8C3O is a DNA G-quadruplex (G4) ligand.Cost-effective and quality-assured.</p>Fórmula:C42H53I3N4O3Pureza:99.72%Forma y color:SolidPeso molecular:1042.61Xanthopterin (hydrate)
CAS:<p>Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species.</p>Fórmula:C6H7N5O3Pureza:98.99% - 99.93%Forma y color:Yellow To Orange Crystalline PowderPeso molecular:197.15Hycanthone
CAS:<p>Hycanthone (Etrenol(mesylate)) is a potent drug of antischistosomal.</p>Fórmula:C20H24N2O2SPureza:98.78%Forma y color:Yellow-Orange Powder (Ntp 1992)Peso molecular:356.48Floxuridine
CAS:Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.Fórmula:C9H11FN2O5Pureza:98.92% - 99.96%Forma y color:SolidPeso molecular:246.19Vitamin D2
CAS:<p>Ergocaliferol (Vitamin D2), derived from ergosterol by UV, inhibits bladder tumor promotion and leukemia, and blocks DNA Polymerase.</p>Fórmula:C28H44OPureza:98.73% - 99.89%Forma y color:Prisms From Acetone 1998)Peso molecular:396.65Farudodstat
CAS:<p>Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH with antitumor activity. It has the potential to be a first-in-class candidate in AML.</p>Fórmula:C19H14F2N2O3Pureza:98.36%Forma y color:SolidPeso molecular:356.32Dithranol
CAS:<p>Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially</p>Fórmula:C14H10O3Pureza:93.49% - 99.33%Forma y color:Physical Description Lemon Yellow Leaflets Or Plates Or An Orange Powder MeltingPeso molecular:226.23MALAT1-IN-1
CAS:<p>MALAT1-IN-1 is an effective dose-dependent Malat1 inhibitor, not altering Neat1 expression.</p>Fórmula:C19H21N3O2Pureza:99.58%Forma y color:SolidPeso molecular:323.39Fludarabine
CAS:<p>Fludarabine (Fludarabinum) is a fluorinated purine analog, an inhibitor of nucleic acid synthesis and an inhibitor of STAT1 activation.</p>Fórmula:C10H12FN5O4Pureza:99.65% - 99.89%Forma y color:White SolidPeso molecular:285.23Enrofloxacin
CAS:<p>Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.</p>Fórmula:C19H22FN3O3Pureza:99.43% - >99.99%Forma y color:Pale Yellow CrystalsPeso molecular:359.39DI-87
CAS:<p>DI-87 (TRE-515) is a novel and orally available dCK (deoxycytidine kinase) inhibitor. DI-87 binds to dCK reduces the production of dNTP inhibits tumor growth.</p>Fórmula:C23H30N6O3S2Pureza:99.76%Forma y color:SolidPeso molecular:502.65Enoxacin
CAS:<p>Enoxacin (NSC-629661) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.</p>Fórmula:C15H17FN4O3Pureza:98.68% - 99.89%Forma y color:Off-White To Yellow CrystalsPeso molecular:320.32Metarrestin
CAS:<p>Metarrestin (ML246) is a first-in-class perinucleolar compartment inhibitor with a favorable PK profile, which effectively suppresses metastasis.</p>Fórmula:C31H30N4OPureza:99.45%Forma y color:SolidPeso molecular:474.6NMDI14
CAS:<p>NMDI14 is an inhibitor of nonsense mediated RNA decay (NMD).</p>Fórmula:C21H25N3O4SPureza:97.79% - 99.37%Forma y color:SolidPeso molecular:415.51Procaine hydrochloride
CAS:<p>Procaine HCl is a benzoic acid derivative used as a local anesthetic, blocking nerve impulses and sensation.</p>Fórmula:C13H20N2O2·HClPureza:99.1% - 99.22%Forma y color:White Crystalline PowderPeso molecular:272.77Oxaliplatin
CAS:<p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>Fórmula:C8H14N2O4PtPureza:97% - 99.93%Forma y color:SolidPeso molecular:397.29DHODH-IN-11
CAS:<p>DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03.</p>Fórmula:C15H11N3O2Pureza:98.14%Forma y color:SolidPeso molecular:265.27Rifapentine
CAS:<p>Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.</p>Fórmula:C47H64N4O12Pureza:95.74% - ≥98%Forma y color:SolidPeso molecular:877.03PTC299
CAS:<p>PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA</p>Fórmula:C25H20Cl2N2O3Pureza:99.72%Forma y color:SolidPeso molecular:467.34Carboplatin
CAS:<p>Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.</p>Fórmula:C6H12N2O4PtPureza:98% - 99.72%Forma y color:White Crystalline PowderPeso molecular:371.25Rifaximin
CAS:<p>Rifaximin: an oral semi-synthetic antibiotic from rifamycin SV; targets bacterial RNA polymerase to halt growth.</p>Fórmula:C43H51N3O11Pureza:99.18% - 99.40%Forma y color:Red-Orange Crystalline PowderPeso molecular:785.88Cytarabine
CAS:<p>Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).</p>Fórmula:C9H13N3O5Pureza:99.83% - 99.93%Forma y color:Fine Off-White Crystalline PowderPeso molecular:243.22Novobiocin Sodium
CAS:<p>Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.</p>Fórmula:C31H35N2NaO11Pureza:99% - 99.28%Forma y color:SolidPeso molecular:634.61Gemcitabine
CAS:<p>Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Fórmula:C9H11F2N3O4Pureza:98.66% - 99.67%Forma y color:SolidPeso molecular:263.25-Fluorouridine
CAS:<p>5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine.</p>Fórmula:C9H11FN2O6Pureza:99.76% - 99.85%Forma y color:White PowderPeso molecular:262.19Phleomycin
CAS:<p>Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage.</p>Fórmula:C48H69N17O20S2Pureza:98%Forma y color:SolidPeso molecular:1268.29Levofloxacin hydrate
CAS:<p>Levofloxacin hydrate (Cravit hydrate) is a third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Fórmula:C18H20FN3O4H2OPureza:98.26%Forma y color:Pale Yellow SolidPeso molecular:370.38TK216
CAS:<p>TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.</p>Fórmula:C19H15Cl2NO3Pureza:97.22%Forma y color:SolidPeso molecular:376.23ART558
CAS:<p>ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM).</p>Fórmula:C21H21F3N4O2Pureza:99.18% - 99.67%Forma y color:SolidPeso molecular:418.41Carmofur
CAS:<p>Carmofur (HCFU) is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.</p>Fórmula:C11H16FN3O3Pureza:98.53% - 99.98%Forma y color:SolidPeso molecular:257.26Folic acid
CAS:<p>Folic acid (Vitamin B9) is a vitamin B9 that is essential for the synthesis of DNA/RNA and for the production new cells. Cost-effective and quality-assured.</p>Fórmula:C19H19N7O6Pureza:99.19% - 99.27%Forma y color:Yellowish-Orange Crystals; Extremely Thin Platelets (Elongated @ 2 Ends) From Hot Water 482°FPeso molecular:441.40Foscarnet sodium
CAS:<p>Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis.</p>Fórmula:CNa3O5PPureza:98.52%Forma y color:White Or Almost White Crystalline PowderPeso molecular:191.95N-Dodecyl-β-D-maltoside
CAS:<p>N-Dodecyl-β-D-maltoside (Lauryl Maltoside) has also been employed in applications such as in the purification and stabilization of RNA polymerase and the</p>Fórmula:C24H46O11Pureza:99.7% - >99.99%Forma y color:White PowderPeso molecular:510.62Enoxacin hydrate
CAS:<p>Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.</p>Fórmula:C15H17FN4O3H2OPureza:99.50%Forma y color:SolidPeso molecular:347.34RG7800
CAS:<p>RG7800 (RO6885247) has the potential for spinal muscular atrophy treatment. RG7800 is an SMN2 splicing modifier.</p>Fórmula:C24H28N6OPureza:99.44%Forma y color:SolidPeso molecular:416.52Hydroxyurea
CAS:<p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>Fórmula:CH4N2O2Pureza:99.85% - 99.92%Forma y color:SolidPeso molecular:76.05JH-RE-06
CAS:<p>JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ.</p>Fórmula:C20H16Cl3N3O4Pureza:99.29%Forma y color:SolidPeso molecular:468.72BAY-2402234
CAS:<p>BAY-2402234: a selective DHODH inhibitor targeting myeloid cancers with low-nanomolar potency.</p>Fórmula:C21H18ClF5N4O4Pureza:98.9%Forma y color:SolidPeso molecular:520.84Adenine
CAS:<p>Adenine: a purine nucleobase vital for ATP, NAD, FAD production, and DNA/RNA synthesis.</p>Fórmula:C5H5N5Pureza:99.39% - 99.95%Forma y color:SolidPeso molecular:135.13Doxifluridine
CAS:<p>Doxifluridine (AMC 0101) is a fluoropyrimidine derivative and oral prodrug of the antineoplastic agent 5-fluorouracil (5-FU) with antitumor activity.</p>Fórmula:C9H11FN2O5Pureza:99.47% - 99.86%Forma y color:White SolidPeso molecular:246.19Cinoxacin
CAS:<p>Cinoxacin (Compound 64716), an older synthetic antimicrobial, was related to the quinolone class of antibiotics.</p>Fórmula:C12H10N2O5Pureza:99.62% - 99.98%Forma y color:SolidPeso molecular:262.22Methotrexate
CAS:<p>Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.</p>Fórmula:C20H22N8O5Pureza:96.84% - 99.91%Forma y color:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisPeso molecular:454.44PZL-A
CAS:<p>PZL-A, PZL-A, an activator of mtDNA synthesis, restored the activity of POLγ mutant variant.</p>Fórmula:C19H17ClN4O2Pureza:99.88%Forma y color:SoildPeso molecular:368.82Famciclovir
CAS:<p>Famciclovir (BRL 42810) inhibits Herpes virus DNA polymerase by mimicking nucleosides.</p>Fórmula:C14H19N5O4Pureza:99.85%Forma y color:Off-White PowderPeso molecular:321.33Procaine
CAS:<p>Procaine (Vitamin H3) is a slow-acting ester local anesthetic with a short effect, used for infiltration, nerve, and spinal blocks.</p>Fórmula:C13H20N2O2Pureza:99.57% - 99.73%Forma y color:Anhydrous Plates Tables From Ligroin Or Ether SolidPeso molecular:236.31Oxolinic acid
CAS:<p>Oxolinic acid (Nidantin) is a synthetic antimicrobial related to NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.</p>Fórmula:C13H11NO5Pureza:98.39% - 99.72%Forma y color:Crystals From Dimethylformamide White Crystalline PowderPeso molecular:261.23Daunorubicin hydrochloride
CAS:<p>Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and protein</p>Fórmula:C27H29NO10·HClPureza:96.21% - 99.53%Forma y color:Cancer DrugPeso molecular:563.99Epirubicin hydrochloride
CAS:<p>Epirubicin hydrochloride (Pharmorubicin) is a Topo and Foxp3 inhibitor. Epirubicin hydrochloride has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C27H30ClNO11Pureza:98.13% - 99.79%Forma y color:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.98EFdA-TP
CAS:<p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>Fórmula:C12H15FN5O12P3Forma y color:SolidPeso molecular:533.195DMT-dG(ib) Phosphoramidite
CAS:<p>DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.</p>Fórmula:C44H54N7O8PPureza:99.21%Forma y color:SolidPeso molecular:839.9223-Oxa-OSW-1
CAS:<p>23-Oxa-OSW-1 (SBF-1), a derivative of OSW-1, serves as a potent inhibitor of the osterol-binding protein (OSBP) with demonstrated antitumor activity [1] [2].</p>Fórmula:C54H82O16Forma y color:SolidPeso molecular:987.22Tilatamig samrotecan
<p>Tilatamig samrotecan (AZD9592) is an antibody-drug conjugate (ADC) designed to deliver a topoisomerase I inhibitor (TOP1i). It targets epidermal growth factor receptor (EGFR) and c-MET and demonstrates antitumor activity. The compound induces DNA double-strand breaks, elevates pRAD50 and γH2AX expression, and inhibits the growth of non-small cell lung cancer.</p>Forma y color:Odour SolidLIN28-IN-2
<p>LIN28-IN-2 (Compound Ln268) blocks the interaction between the zinc finger domain (ZKD) of Lin28 and RNA substrates, inhibiting both Lin28a and Lin28b. It also suppresses the proliferation of Lin28-positive cancer cells and the growth of 3D spheroids.</p>Fórmula:C9H7FN2O2SForma y color:SolidPeso molecular:226.227RNase L ligand 1
<p>RNase L ligand 1 (Compound F1-COOH) serves as a ligand for RNase L and is utilized in the synthesis of F1-RIBOTAC.</p>Fórmula:C21H21Cl2NO3Forma y color:SolidPeso molecular:406.302DIZ-3
CAS:<p>DIZ-3: Selective G4 ligand, stabilizes structure, inhibits ALT cancer cell growth by inducing cell cycle arrest and apoptosis.</p>Fórmula:C46H44F2N8Forma y color:SolidPeso molecular:746.895'-O-DMT-rI
CAS:<p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>Fórmula:C31H30N4O7Forma y color:SolidPeso molecular:570.59KWR137
<p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>Fórmula:C33H31ClF3N9O4Forma y color:SolidPeso molecular:710.105Clofarabine-5'-triphosphate
CAS:<p>Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.</p>Fórmula:C10H14ClFN5O12P3Forma y color:SolidPeso molecular:543.625'-O-DMT-PAC-dA
CAS:<p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>Fórmula:C39H37N5O7Forma y color:SolidPeso molecular:687.74LB80317
CAS:<p>LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.</p>Fórmula:C10H14N5O5PForma y color:SolidPeso molecular:315.22S-MGB-234
CAS:<p>S-MGB-234 treats AAT, effective against T. congolense and T. vivax, no cross-resistance or shared transport with diamidines.</p>Fórmula:C30H32N8O4Forma y color:SolidPeso molecular:568.638RNA recruiter 2
<p>RNA recruiter 2 serves as a QSOX1mRNA ligand. This compound functions as a target RNA ligand (RIBOTAC's target RNA ligand) and aids in developing RIBOTAC RNA degraders with antitumor activity. Additionally, RNA recruiter 2 is utilized in the synthesis of F1-RIBOTAC.</p>Fórmula:C20H16FNO4SForma y color:SolidPeso molecular:385.409Deoxythymidine-5'-triphosphate sodium hydrate
<p>dTTP sodium hydrate, a DNA synthesis component, is a nucleoside triphosphate.</p>Fórmula:C10H17N2O14P3·xNa·xH2OForma y color:SolidPeso molecular:C10H17N2O14P3.xNa.xH2OGuanosine triphosphate
CAS:<p>Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].</p>Fórmula:C10H16N5O14P3Forma y color:SolidPeso molecular:523.18DNA31
CAS:<p>DNA31 is a potent RNA polymerase inhibitor.</p>Fórmula:C48H58N4O13Pureza:98%Forma y color:SolidPeso molecular:898.997-TFA-ap-7-Deaza-ddG
CAS:<p>Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.</p>Fórmula:C16H16F3N5O4Forma y color:SolidPeso molecular:399.33Phen-DC3 Trifluoromethanesulfonate
CAS:<p>Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.</p>Fórmula:C36H26F6N6O8S2Pureza:98%Forma y color:SolidPeso molecular:848.75m7GpppGmpG
CAS:<p>m7GpppGmpG, a trinucleotide 5′ cap analog, exhibits capping efficiencies of 86% for the RNAs obtained [1].</p>Fórmula:C32H43N15O25P4Forma y color:SolidPeso molecular:1161.66Nuclease S1
CAS:<p>Nuclease S1 breaks down ssDNA and RNA, trims protruding ends of dsDNA.</p>Forma y color:SolidUCK2 Inhibitor-3
CAS:<p>UCK2 Inhibitor-3 blocks UCK2 (IC50: 16.6μM) and DNA polymerases eta/kappa (IC50s: 56μM/16μM), aiding uridine salvage in certain cells.</p>Fórmula:C19H13BrFN5O2SForma y color:SolidPeso molecular:474.31FF-10502
CAS:<p>FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.</p>Fórmula:C9H12FN3O3SForma y color:SolidPeso molecular:261.27PRV-IN-1
<p>PRV-IN-1 (compound c14) demonstrates significant antiviral activity against pseudorabies virus (PRV) with an EC50 of 14 pM and a CC50 of 343.7 μM. It effectively inhibits the replication of PRV.</p>Fórmula:C20H28N4O3Forma y color:SolidPeso molecular:372.461Agrocin 84
CAS:<p>Agrocin 84 is a microbial metabolite that inhibits DNA and protein synthesis, as well as amino acid transport, in the susceptible and virulent Agrobacterium strain H-38-9.</p>Fórmula:C22H36N6O16P2Forma y color:SolidPeso molecular:702.499RAD51-IN-3
CAS:<p>RAD51-IN-3 is a Rad51 inhibitor.</p>Fórmula:C31H41N5O5S2Forma y color:SolidPeso molecular:627.82Votoplam HCl
CAS:<p>Votoplam HCl is a systemically acting gene splicing regulator that down-regulates the levels of huntingtin protein, which to inhibit Huntington's disease (HD).</p>Fórmula:C21H26ClN9OPureza:99.02%Forma y color:SoildPeso molecular:455.94KC12
<p>KC12 acts as an inhibitor of the FOXM1 transcription factor. In cancer cells of the MDA-MB-231 line, KC12 exhibits cytotoxicity with an IC50 of 6.13 µM.</p>Fórmula:C23H17F3N2O3SForma y color:SolidPeso molecular:458.453Anticancer agent 262
<p>Anticanceragent 262 (compound 3h) is a DNA-intercalating antineoplastic agent with an IC50 value of 5.7 µM against A549 cancer cells.</p>Fórmula:C26H31N3OForma y color:SolidPeso molecular:401.544dUTP trisodium
CAS:<p>dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.</p>Fórmula:C9H12N2Na3O14P3Pureza:100.00%Forma y color:SolidPeso molecular:534.09TH1085
CAS:<p>TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).</p>Fórmula:C17H21N3Pureza:99.99%Forma y color:SolidPeso molecular:267.37m7Gpppm6AmpG
CAS:<p>m7Gpppm6AmpG, a trinucleotide mRNA 5’ cap analog, facilitates RNA synthesis in vitro [1].</p>Fórmula:C33H45N15O24P4Forma y color:SolidPeso molecular:1159.69NLS (PKKKRKV)
CAS:<p>NLS (PKKKRKV) peptide from SV40 big T antigen boosts nuclear entry for gene transfer studies.</p>Fórmula:C40H78N14O8Pureza:98%Forma y color:SolidPeso molecular:883.14m7GpppApG
CAS:<p>M7GpppApG is a trinucleotide mRNA 5' cap analog utilized for in vitro RNA synthesis [1].</p>Fórmula:C31H41N15O24P4Forma y color:SolidPeso molecular:1131.64Bisucaberin
CAS:<p>Bisucaberin: a siderophore with anticancer properties; inhibits L1210/1MC cells and enhances 1023 cell cytolysis.</p>Fórmula:C18H32N4O6Forma y color:SolidPeso molecular:400.476T-2513
CAS:<p>T-2513 inhibits topoisomerase I by covalently bonding to its DNA complex, blocking DNA replication and causing cell death.</p>Fórmula:C25H27N3O5Forma y color:SolidPeso molecular:449.507WRN inhibitor 17
CAS:<p>WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.</p>Fórmula:C33H34F4N4O6SForma y color:SolidPeso molecular:690.71Orotidine 5′-monophosphate trisodium
CAS:<p>Orotidine 5'-monophosphate trisodium, a pyrimidine nucleotide, is synthesized through the de novo DNA synthesis pathway by various microorganisms, including M.</p>Fórmula:C10H10N2Na3O11PForma y color:SolidPeso molecular:434.14Dezecapavir
CAS:<p>Dezecapavir (example 4) acts as an effective inhibitor of viral replication, exhibiting an EC50 value of 0.025 nM in MT2 cells with a CC50 greater than 0.5 μM.</p>Fórmula:C37H29ClF9N9O5SForma y color:SolidPeso molecular:918.19Ac-dA Phosphoramidite
CAS:<p>Ac-dA Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Fórmula:C42H50N7O7PForma y color:SolidPeso molecular:795.878SD49-7
CAS:<p>SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 µM.</p>Fórmula:C18H14N2O3Pureza:99.91%Forma y color:SoildPeso molecular:306.32Emicoron
CAS:Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.Fórmula:C52H58N6O4Pureza:98%Forma y color:SolidPeso molecular:831.05VPC-18005
CAS:<p>VPC-18005: a luciferase inhibitor that blocks ERG-induced transcription by binding ERG-ETS, hindering DNA attachment.</p>Fórmula:C15H17N3O3SPureza:99.95%Forma y color:SoildPeso molecular:319.385-Iminodaunorubicin
CAS:<p>5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.</p>Fórmula:C27H30N2O9Forma y color:SolidPeso molecular:526.545'-O-TBDMS-dU
CAS:<p>5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides.</p>Fórmula:C15H26N2O5SiForma y color:SolidPeso molecular:342.4672'-(2-Nitrobenzyl)-ATP trisodium
<p>2'-(2-Nitrobenzyl)-ATP trisodium is an rATP analogue that acts as a transcription terminator. It inhibits T7 RNA polymerase from continuing RNA chain extension.</p>Fórmula:C17H18N6Na3O15P3Forma y color:SolidPeso molecular:707.973615'-O-DMT-2'-O-TBDMS-Bz-rC
CAS:<p>5'-O-DMT-2'-O-TBDMS-Bz-rC, a modified nucleoside, is utilized in the synthesis of DNA or RNA.</p>Fórmula:C43H49N3O8SiForma y color:SolidPeso molecular:763.95Cytarabine triphosphate
CAS:<p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>Fórmula:C9H16N3O14P3Forma y color:SolidPeso molecular:483.16Thio-ITP
CAS:<p>Thio-ITP (6-Thioinosine 5'-triphosphate) inhibits RNA polymerases I & II with Ki of 40.9 & 38.0 μM.</p>Fórmula:C10H15N4O13P3SForma y color:SolidPeso molecular:524.23TAC
CAS:<p>TAC is a TERT (telomerase reverse transcriptase) activator, promotes telomere synthesis, reduces cellular senescence and inflammatory cytokines</p>Fórmula:C14H12ClF2NO2SPureza:99.20%Forma y color:SolidPeso molecular:331.77Bromochloroacetonitrile
CAS:<p>Bromochloroacetonitrile, a water disinfection by-product, is mutagenic and can break DNA strands.</p>Fórmula:C2HBrClNForma y color:SolidPeso molecular:154.39Vanoxonin
CAS:<p>Vanoxonin is a new thymidylate synthetase inhibitor.</p>Fórmula:C18H25N3O9Pureza:98%Forma y color:SolidPeso molecular:427.41MRK-952
<p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>Fórmula:C20H20ClF3N6Forma y color:SolidPeso molecular:436.8615'-O-DMT-2'-O-TBDMS-Ac-rC
CAS:<p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C38H47N3O8SiForma y color:SolidPeso molecular:701.892Uridine triphosphate 13C9,15N2 sodium
CAS:<p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>Fórmula:C9H1415N2NaO15P3Forma y color:SolidPeso molecular:517.04Ac-rC Phosphoramidite
CAS:<p>Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.</p>Fórmula:C47H64N5O9PSiPureza:98.29%Forma y color:SolidPeso molecular:902.1Remdesivir nucleoside monophosphate
CAS:<p>Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.</p>Fórmula:C12H14N5O7PForma y color:SolidPeso molecular:371.245-BrdUTP sodium salt
CAS:<p>5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks.</p>Fórmula:C9H10BrN2Na4O14P3Pureza:98%Forma y color:SolidPeso molecular:634.97RNA splicing modulator 3
CAS:<p>RNA Splicing Modulator 3 (Compound 236) is an effective RNA splicing modulator, exhibiting an AC50 value of less than 100 nM [1].</p>Fórmula:C19H20N6OSForma y color:SolidPeso molecular:380.478-NH2-ATP
CAS:<p>8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.</p>Fórmula:C10H17N6O13P3Forma y color:SolidPeso molecular:522.203'-Deoxyuridine-5'-triphosphate trisodium
<p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>Fórmula:C9H12N2Na3O14P3Forma y color:SoildPeso molecular:534.08HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
CAS:<p>HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.</p>Fórmula:C57H62N8O10SForma y color:SolidPeso molecular:1051.212'-OMe-Ac-C Phosphoramidite
CAS:<p>2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.</p>Fórmula:C42H52N5O9PForma y color:SolidPeso molecular:801.86CW-2
<p>CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).</p>Fórmula:C43H42Cl2FN11O10PtForma y color:SolidPeso molecular:1156.21251Demycarosyl-3D-β-D-digitoxosylmithramycin SK
CAS:<p>Demycarosyl-3D-β-D-digitoxosylmithramycin SK, an analog of Mithramycin, exhibits potent anti-tumor activity.</p>Fórmula:C50H72O23Forma y color:SolidPeso molecular:1041.09Bz-rC Phosphoramidite
CAS:<p>Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Fórmula:C52H66N5O9PSiForma y color:SolidPeso molecular:964.185DNA Gyrase-IN-15
<p>DNA Gyrase-IN-15 (Compound 11) is an antibacterial agent that inhibits both DHPS and DNA gyrase, with IC50 values of 1.73 and 0.07 µM, respectively. It shows antimicrobial activity against Enterococcus faecium (MIC of 15.62 µg/mL), Acinetobacter baumannii, Enterobacter (MIC of 7.81 µg/mL), Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus. Additionally, DNA Gyrase-IN-15 exhibits antibiofilm activity against Enterococcus faecium.</p>Fórmula:C31H26N4O4S2Forma y color:SolidPeso molecular:582.693Carbazole
CAS:<p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>Fórmula:C12H9NPureza:99.82%Forma y color:SolidPeso molecular:167.211Guanosine 5'-triphosphate trisodium salt hydrate
CAS:<p>5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.</p>Fórmula:C10H18N5NaO15P3Pureza:98%Forma y color:SolidPeso molecular:564.185Ribonuclease T1
CAS:<p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>Forma y color:SolidEFdA-TP tetraammonium
<p>EFdA-TP tetraammonium is a potent HIV-1 RT inhibitor and DNA synthesis blocker, acting as an ICT or DCT.</p>Fórmula:C12H27N9O12P3Forma y color:SolidPeso molecular:601.31TS-002902
<p>TS-002902 is a small molecule inhibitor of TUT4/7, exhibiting antiproliferative activity. It holds potential for use in cancer research.</p>Forma y color:Odour Solidcis-Lomibuvir
CAS:<p>cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.</p>Fórmula:C25H35NO4SForma y color:SolidPeso molecular:445.61RNA polymerase II-IN-2
<p>RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.</p>Fórmula:C41H58N10O12SForma y color:SolidPeso molecular:915.027-TFA-ap-7-Deaza-ddA
CAS:<p>Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.</p>Fórmula:C16H16F3N5O3Forma y color:SolidPeso molecular:383.331AV-153
CAS:<p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>Fórmula:C14H19NNaO6Forma y color:SolidPeso molecular:320.2975'-O-DMT-N4-Bz-2'-F-dC
CAS:<p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>Fórmula:C37H34FN3O7Forma y color:SolidPeso molecular:651.683'Ome-m7GpppAmpG
CAS:<p>3'Ome-m7GpppAmpG is a trinucleotide cap with LNA, boosting translation; useful in mRNA vaccines and gene therapy.</p>Fórmula:C33H45N15O24P4Forma y color:SolidPeso molecular:1159.697-Deazaxanthine
CAS:<p>7-Deazaxanthine (7DX) is an inhibitor of thymidine phosphorylase (TPase) and reduces TPase activity in a concentration-dependent manner, with an IC50 value of 40 μM. Additionally, 7-Deazaxanthine exhibits significant anti-angiogenic properties.</p>Fórmula:C6H5N3O2Forma y color:SolidPeso molecular:151.12FR901463
CAS:<p>FR 901463 is a biochemical.</p>Fórmula:C27H42ClNO8Forma y color:SolidPeso molecular:544.08L82-G17
CAS:<p>L82-G17 is an uncompetitive LigI-selective inhibitor in human cells with utility as a probe of the catalytic activity and cellular functions of LigI.</p>Fórmula:C11H9ClN4O2Pureza:99.69%Forma y color:SolidPeso molecular:264.67DMT-5Me-dC(Bz)-CE Phosphoramidite
CAS:<p>DMT-5Me-dC(Bz)-CE Phosphoramidite aids in crafting LNAs for better fluorescent probes.</p>Fórmula:C47H54N5O8PForma y color:SolidPeso molecular:847.932'-Deoxy-2'-fluoro-l-uridine
CAS:<p>2'-Deoxy-2'-fluoro-1-uridine: an L-nucleoside, inhibits RNA viruses by blocking viral RNA polymerase.</p>Fórmula:C9H11FN2O5Forma y color:SolidPeso molecular:246.19Maleuric acid
CAS:<p>Maleuric acid is an anti-mitotic agent for research and boosts growth and fertility in flora and fauna.</p>Fórmula:C5H6N2O4Pureza:98.92%Forma y color:SolidPeso molecular:158.11c-Fos-IN-1
<p>c-Fos-IN-1 (Compound P16) acts as a c-Jun inhibitor, effectively reducing the mRNA and protein levels of c-Fos. It also inhibits the phosphorylation activity of ERK and the transcriptional activity of AP-1. This compound demonstrates anticancer properties through the inhibition of the ERK/c-Fos/Jun pathway. c-Fos-IN-1 curbs the proliferation and migration of gastric cancer cells, with an IC50 of 2.31 μM for MGC-803 cells, causing cell cycle arrest at the G2/M phase and inducing apoptosis in cancer cells. Additionally, c-Fos-IN-1 hampers the growth of gastric cancer tumors.</p>Fórmula:C28H35NO3Forma y color:SolidPeso molecular:433.582Deoxythymidine-5'-triphosphate
CAS:<p>Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.</p>Fórmula:C10H17N2O14P3Forma y color:SolidPeso molecular:482.1675'-O-DMT-N4-Ac-2'-F-dC
CAS:<p>5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C32H32FN3O7Forma y color:SolidPeso molecular:589.61Suricapavir
CAS:<p>Suricapavir is an effective viral replication inhibitor with antiviral activity.</p>Fórmula:C41H29ClF9N9O4SForma y color:SolidPeso molecular:950.23SR15006
CAS:<p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>Fórmula:C16H20ClN3O4SPureza:99.87%Forma y color:SoildPeso molecular:385.87N6-Methyladenine
CAS:<p>N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.</p>Fórmula:C6H7N5Pureza:99.78%Forma y color:SolidPeso molecular:149.15Diguanosine 5′-triphosphate
CAS:<p>Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.</p>Fórmula:C20H27N10O18P3Forma y color:SolidPeso molecular:788.4095'-O-DMT-rU
CAS:<p>5’-O-DMT-rU is a modified nucleoside and can be used to synthesize RNA.</p>Fórmula:C30H30N2O8Forma y color:SolidPeso molecular:546.575'-O-TBDMS-dG
CAS:<p>5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.</p>Fórmula:C16H27N5O4SiForma y color:SolidPeso molecular:381.50(+)-Glaucarubinone
<p>(+)-Glaucarubinone is a natural product that can be used as a reference standard.</p>Fórmula:C25H34O10Forma y color:SolidPeso molecular:494.537Clofarabine-5'-diphosphate trisodium
<p>Clofarabine-5'-diphosphatetrisodium (Clofarabine-DP trisodium) is the sodium salt form of Clofarabine-5'-diphosphate. As a metabolic product of Clofarabine, it results from phosphorylation by deoxycytidine kinase (dCK). Clofarabine-5'-diphosphate trisodium can undergo further phosphorylation to form Clofarabine-5'-triphosphate, demonstrating cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>Fórmula:C10H10ClFN5Na3O9P2Forma y color:SolidPeso molecular:529.58Mulnitorsen
CAS:<p>Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].</p>Fórmula:C172H217N74O82P17S17Forma y color:SolidPeso molecular:5704.66Cy5-dATP
<p>Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .</p>Fórmula:C47H58N7O19P3S2Forma y color:SolidPeso molecular:1182.055'-O-TBDMS-N2-ibu-dG
CAS:<p>5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.</p>Fórmula:C20H33N5O5SiForma y color:SolidPeso molecular:451.59Pyrindamycin A
CAS:<p>Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.</p>Fórmula:C26H26ClN3O8Pureza:98%Forma y color:SolidPeso molecular:543.95YL-5092
<p>YL-5092 is an inhibitor of YT521-B homology (YTH) domain-containing protein 1 (YTHDC1). It inhibits acute myeloid leukemia cells with an IC50 of 0.28-2.87 μM. YL-5092 exhibits antitumor activity in xenograft mice models using MOLM-13 or U937 cells.</p>Fórmula:C22H14F3N3O2SForma y color:SolidPeso molecular:441.435'-O-DMT-N2-DMF-dG
CAS:<p>5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.</p>Fórmula:C34H36N6O6Forma y color:SolidPeso molecular:624.698ddGTP trisodium
<p>ddGTP trisodium, a ddNTP, inhibits or serves as a substrate for DNA polymerase α, halting DNA chain elongation.</p>Fórmula:C10H13N5Na3O12P3Forma y color:SolidPeso molecular:557.13N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
CAS:<p>N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].</p>Fórmula:C21H35N12O17P3Forma y color:SolidPeso molecular:820.49(S)-DI-87
CAS:<p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>Fórmula:C23H30N6O3S2Pureza:99.42%Forma y color:SoildPeso molecular:502.65wrwycr-NH2 TFA
<p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>Forma y color:Odour SolidIBU-DC Phosphoramidite
CAS:<p>IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.</p>Fórmula:C43H54N5O8PForma y color:SolidPeso molecular:799.9062'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS:<p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>Fórmula:C10H14N5Na2O8PForma y color:SolidPeso molecular:409.202TS-002266
CAS:<p>TS-0022666 is a selective TUT4/7 inhibitor, antiproliferative and anti-leukaemic in vivo and in vitro, cancers with FOCAD deficiency.</p>Fórmula:C31H32Cl2N6O5Pureza:98.18%Forma y color:SoildPeso molecular:639.53Vasoactive intestinal contractor
CAS:<p>Vasoactive intestinal contractor, a novel member of the endothelin family, stimulates a rapid increase in intracellular Ca2+ concentration in fura-2-overexpressed Swiss 3T3 cells [1.</p>Fórmula:C116H161N27O32S4Forma y color:SolidPeso molecular:2573.94R-1479
CAS:<p>R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.</p>Fórmula:C9H12N6O5Pureza:98.11% - 99.95%Forma y color:SolidPeso molecular:284.2312R-LOX-IN-2
CAS:<p>12R-LOX-IN-2 is a 12R-LOX inhibitor that inhibits the hyperproliferation of psoriatic cells and can be used in the study of psoriasis and other skin diseases.</p>Fórmula:C19H13NOPureza:99.84%Forma y color:SolidPeso molecular:271.31Clofarabine-5'-diphosphate
CAS:<p>Clofarabine-5'-diphosphate (Clofarabine-DP) is a metabolite resulting from the phosphorylation of Clofarabine by deoxycytidine kinase (dCK). It can undergo further phosphorylation to become Clofarabine-5'-triphosphate, exhibiting cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>Fórmula:C10H13ClFN5O9P2Forma y color:SolidPeso molecular:463.645'-O-TBDMS-Bz-dA
CAS:<p>5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.</p>Fórmula:C23H31N5O4SiForma y color:SolidPeso molecular:469.617m7GpppAmpG
CAS:<p>M7GpppAmpG is a trinucleotide 5′ cap analog, exhibiting capping efficiencies of 90% for the produced RNAs [1].</p>Fórmula:C32H43N15O24P4Forma y color:SolidPeso molecular:1145.66Antipain
CAS:<p>Antipain, from Actinomycetes, blocks proteases and combats MNNG-induced genetic changes.</p>Fórmula:C27H44N10O6Pureza:98%Forma y color:SolidPeso molecular:604.713DG1
<p>DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing</p>Fórmula:C19H17N5O5SForma y color:SolidPeso molecular:427.4313-TP
<p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>Fórmula:C12H19F2N6O12P3Forma y color:SolidPeso molecular:570.23Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Fórmula:C21H25FN4O2Forma y color:SolidPeso molecular:384.45Thailanstatin C
CAS:<p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>Fórmula:C30H46ClNO9Forma y color:SolidPeso molecular:600.15BRP
BRP, a peptide related to BRINP2, exhibits anti-obesity activity through the activation of FOS. It triggers FOS activation in the central nervous system, and its effect is independent of leptin, GLP-1 receptor, and melanocortin 4 receptor.Forma y color:Odour Solid5-Methylcytidine 5′-triphosphate
CAS:<p>5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate</p>Fórmula:C10H18N3O14P3Forma y color:SolidPeso molecular:497.18Garenoxacin
CAS:<p>Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.</p>Fórmula:C23H20F2N2O4Pureza:98%Forma y color:SolidPeso molecular:426.41Ditercalinium chloride
CAS:<p>Ditercalinium chloride, an anticancer agent, inhibits human DNA polymerase gamma activity and can deplete mitochondrial DNA in both mouse and human cells. Additionally, Ditercalinium chloride is a potential ligand against the COMMD10-AP3S1 fusion protein [1] [2].</p>Fórmula:C46H50Cl2N6O2Forma y color:SolidPeso molecular:789.835-O-TBDMS-N4-Benzoyl-2-deoxycytidine
CAS:<p>5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.</p>Fórmula:C22H31N3O5SiForma y color:SolidPeso molecular:445.58HDAC-IN-85
<p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>Fórmula:C24H27FN4O5Forma y color:SolidPeso molecular:470.49RNA binder 1
<p>RNA binder 1 (Compound 4b) is an RNA-binding agent capable of crossing the blood-brain barrier. It selectively binds to the G-quadruplex structure of the G4C2 repeat sequence RNA of the C9orf72 gene. This compound significantly reduces levels of the toxic polypeptides poly(GA) and poly(GP) in cells derived from amyotrophic lateral sclerosis (ALS) patients, while it has no significant impact on the antisense polypeptide poly(PR), demonstrating selectivity for sense RNA. RNA binder 1 is useful for studying ALS and frontotemporal dementia (FTD).</p>Fórmula:C22H20N10S2Forma y color:SolidPeso molecular:488.13138POLRMT-IN-1
<p>POLRMT-IN-1 (compound S7) is an inhibitor of POLRMT, specifically utilized in cancer-related research.</p>Forma y color:Odour SolidNusinersen
CAS:<p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>Pureza:98.62%Forma y color:SolidN1-Methylpseudouridine-5′-triphosphate tetralithium
<p>N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.</p>Fórmula:C10H13Li4N2O15P3Forma y color:SolidPeso molecular:521.9Carboxy-pyridostatin
CAS:<p>Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.</p>Fórmula:C35H34N10O7Forma y color:SolidPeso molecular:706.715'-O-DMT-ibu-dC
CAS:<p>5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.</p>Fórmula:C34H37N3O7Forma y color:SolidPeso molecular:599.67ML-60218
CAS:<p>ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.</p>Fórmula:C19H15Cl2N3O2S2Pureza:98.1%Forma y color:SolidPeso molecular:452.3816,16-dimethyl Prostaglandin A1
CAS:<p>16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.</p>Fórmula:C22H36O4Forma y color:SolidPeso molecular:364.526Chrexanthomycin C
<p>Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.</p>Fórmula:C31H24O15Forma y color:SolidPeso molecular:636.51PAT-LM1
<p>PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.</p>Forma y color:Odour Liquid5'-O-DMT-Bz-rC
CAS:<p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C37H35N3O8Forma y color:SolidPeso molecular:649.695-Methylcytidine 5′-triphosphate trisodium
<p>5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while</p>Fórmula:C10H15N3Na3O14P3Forma y color:SolidPeso molecular:563.13M7G(3'-OMe-5')pppA(2'-OMe)
<p>M7G(3'-OMe-5')pppA(2'-OMe) is a cap analogue for mRNA synthesis in vitro.</p>Fórmula:C23H33N10O17P3Forma y color:SolidPeso molecular:814.49GS-443902 trisodium
CAS:<p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>Fórmula:C12H16N5O13P3·xNaForma y color:SolidCytidine 5'-diphosphate trisodium salt
CAS:<p>CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.</p>Fórmula:C9H15N3Na3O11P2Pureza:99.55%Forma y color:White Crystalline PowderPeso molecular:472.155'-O-TBDMS-dA
CAS:<p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Fórmula:C16H27N5O3SiForma y color:SolidPeso molecular:365.509Nitrosofolic acid
CAS:<p>Nitrosofolic acid is a folic acid derivaive.</p>Fórmula:C19H18N8O7Forma y color:SolidPeso molecular:470.40Carboxy pyridostatin trifluoroacetate salt
<p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>Fórmula:C37H35F3N10O9Pureza:98%Forma y color:SolidPeso molecular:820.73CTP Synthetase-IN-1 Ammonium salt
<p>CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infections</p>Fórmula:C20H22F3N7O3S2Pureza:99.97%Forma y color:SolidPeso molecular:529.56RNA splicing modulator 1
CAS:<p>RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].</p>Fórmula:C19H20N6OSForma y color:SolidPeso molecular:380.47Lorutengitide
CAS:<p>Lorutengitide is a transcription-regulating peptide with antiproliferative activity.</p>Fórmula:C30H50N8O12Forma y color:SolidPeso molecular:714.764Xanthosine-5'-Triphosphate
CAS:<p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>Fórmula:C10H15N4O15P3Forma y color:SolidPeso molecular:524.164CSN5-IN-2
<p>CSN5-IN-2 (Compound 31) is a CSN5 inhibitor with an IC50 of 0.36 μM. It increases Cullin 1 neddylation levels in cancer cells and downregulates the expression of RAD51 and PD-L1. CSN5-IN-2 exhibits antitumor activity, which is enhanced when used in combination with Talazoparib.</p>Forma y color:Odour SolidPseudorabies virus-IN-1
<p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>Fórmula:C27H23ClF2N4O2Forma y color:SolidPeso molecular:508.947
